Protein kinases in complex with HV2

Total number of genes: 2
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 5S7IB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QALA 1.57 Active DFGin BLAminus in-in in-in HV2 HV2 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IB 1.3 Inactive DFGin BLAminus in-out in-in LU8 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric

Protein kinases in complex with HV2

Total number of genes: 2
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 5S7IB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QALA 1.57 Active DFGin BLAminus in-in in-in HV2 HV2 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7IB 1.3 Inactive DFGin BLAminus in-out in-in LU8 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 HV2 Type1 Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric Allosteric

Protein kinases in complex with HV2

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type