5FBO

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_HUMAN
Organism: Homo sapiens
Domain boundary: 402 - 653
Resolu: 1.894

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out none-out 5WH 5WE Type1.5_Back Allosteric 392 - 659 13
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       398        408        418        428 
glgYGSWEID PKDLTFLKEL GTGQFGVVKY GKWRGQYDVA 
       438        448        458        468 
IKMIKEGSMS EDEFIEEAKV MMNLSHEKLV QLYGVCTKQR 
       478        488        498        508 
PIFIITEYMA NGCLLNYLRE MRHRFQTQQL LEMCKDVCEA 
       518        528        538        548 
MEYLESKQFL HRDLAARNCL VNDQGVVKVS DFGLSryvld 
       558        568        578        588 
deytssvgSK FPVRWSPPEV LMYSKFSSKS DIWAFGVLMW 
       598        608        618        628 
EIYSLGKMPY ERFTNSETAE HIAQGLRLYR PHLASEKVYT 
       638        648        658 
IMYSCWHEKA DERPTFKILL SNILDVMDEE S
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None