| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | BLAminus | in-in | in-out | B97 MW8 | Type1 Allosteric | 44 - 330 | 8 |
| B | None | DFGin | BLAminus | in-in | in-none | B97 MW8 | Type1 Allosteric | 45 - 329 | 9 |
| C | None | DFGin | BLAminus | in-in | in-none | B97 MW8 | Type1 Allosteric | 44 - 329 | 10 |
| D | Inactive | DFGin | BLAminus | in-in | in-out | B97 MW8 | Type1 Allosteric | 44 - 331 | 8 |
| E | Inactive | DFGin | BLAminus | in-in | in-out | B97 MW8 | Type1 Allosteric | 45 - 329 | 8 |
| F | Inactive | DFGin | BLAminus | in-in | in-out | B97 MW8 | Type1 Allosteric | 45 - 329 | 9 |
Representative sequence - Chain F
- - 49 59
mgsshhhhhh ssgenlyfqg sqqfpQFHVK SGLQIKKNAI
69 79 89 99
IDDYKVTSQV LGLGINGKVL QIFNKRTQEK FALKMLQDCP
109 119 129 139
KARREVELHW RASQCPHIVR IVDVYENLYA GRKCLLIVME
149 159 169 179
CLDGGELFSR IQDRGDQAFT EREASEIMKS IGEAIQYLHS
189 199 209 219
INIAHRDVKP ENLLYTSKRP NAILKLTDFG FAKETTshns
229 239 249 259
ltepcYTPYY VAPEVLGPEK YDKSCDMWSL GVIMYILLCG
269 279 289 299
YPPFYSNHGL AISPGMKTRI RMGQYEFPNP EWSEVSEEVK
309 319 329
MLIRNLLKTE PTQRMTITEF MNHPWIMQST kvpqeplht