Protein kinases in complex with SKE

Total number of genes: 4
Total number of chains: 13
Spatial Dihedral Chains Representative
DFGin BLAminus 6 4QMUA
DFGin ABAminus 3 5DT0A
DFGin None 3 8B99A
None None 1 5OBRA

Database table as tsv
Group Gene UniprotID Protein PDB Reso Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 3AMAA 1.75 Active DFGin BLAminus in-in in-in SKE Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DPVA 2.285 Inactive DFGin ABAminus out-in in-out 5DN SKE Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR6A 2.534 Inactive DFGin ABAminus out-in in-out 5E1 SKE Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT0A 2.15 Inactive DFGin ABAminus in-in in-out SKE Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR9A 2.47 Inactive DFGin BLAminus out-out out-out SKE 5E2 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBRA 2.62 Inactive None None out-out out-out 9QT SKE Allosteric Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4QMUA 1.546 Active DFGin BLAminus in-in in-in SKE Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5USYA 2.0 Active DFGin BLAminus in-in in-in SKE Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5USYB 2.0 Active DFGin BLAminus in-in in-in SKE Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6DRWA 2.303 Inactive DFGin BLAminus in-out in-in SKE Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8B99A 1.6 Inactive DFGin None out-none out-out SKE Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5WINA 2.38 Inactive DFGin None out-none out-out SKE Type1
TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5USZA 2.103 Inactive DFGin None in-none out-out SKE Type1

Protein kinases in complex with SKE

Total number of genes: 4
Total number of chains: 13
Spatial Dihedral Chains Representative
DFGin BLAminus 6 4QMUA
DFGin ABAminus 3 5DT0A
DFGin None 3 8B99A
None None 1 5OBRA

Database table as tsv
Organism Group Gene UniprotID Protein PDB Reso Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens AGC PRKACA KAPCA_HUMAN cAMP-dependent protein kinase catalytic subunit alpha 3AMAA 1.75 Active DFGin BLAminus in-in in-in SKE Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DPVA 2.285 Inactive DFGin ABAminus out-in in-out 5DN SKE Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR6A 2.534 Inactive DFGin ABAminus out-in in-out 5E1 SKE Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DT0A 2.15 Inactive DFGin ABAminus in-in in-out SKE Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5DR9A 2.47 Inactive DFGin BLAminus out-out out-out SKE 5E2 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OBRA 2.62 Inactive None None out-out out-out 9QT SKE Allosteric Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4QMUA 1.546 Active DFGin BLAminus in-in in-in SKE Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5USYA 2.0 Active DFGin BLAminus in-in in-in SKE Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5USYB 2.0 Active DFGin BLAminus in-in in-in SKE Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 6DRWA 2.303 Inactive DFGin BLAminus in-out in-in SKE Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 8B99A 1.6 Inactive DFGin None out-none out-out SKE Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5WINA 2.38 Inactive DFGin None out-none out-out SKE Type1
Homo sapiens TYR JAK2 JAK2_HUMAN Tyrosine-protein kinase JAK2 5USZA 2.103 Inactive DFGin None in-none out-out SKE Type1

Protein kinases in complex with SKE

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative

Database table as tsv

Organism Group Gene UniprotID Protein PDB Reso Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type