4AW2

CDC42BPA (Serine/threonine-protein kinase MRCK alpha)
Group: AGC
Uniprot: MRCKA_RAT
Organism: Rattus norvegicus
Domain boundary: 77 - 343
Resolu: 1.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 22E Allosteric 2 - 417 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        11         21         31         41 
SGEVRLRQLE QFILDGPAQT NGQCFSVETL LDILICLYDE 
        51         61         71         81 
CNNSPLRREK NILEYLEWAK PFTSKVKQMR LHREDFEILK 
        91        101        111        121 
VIGRGAFGEV AVVKLKNADK VFAMKILNKW EMLKRAETAC 
       131        141        151        161 
FREERDVLVN GDSKWITTLH YAFQDDNNLY LVMDYYVGGD 
       171        181        191        201 
LLTLLSKFED RLPEEMARFY LAEMVIAIDS VHQLHYVHRD 
       211        221        231        241 
IKPDNILMDM NGHIRLADFG SCLKLMEDGT VQSSVAVGTP 
       251        261        271        281 
DYISPEILQA MEGGKGRYGP ECDWWSLGVC MYEMLYGETP 
       291        301        311        321 
FYAESLVETY GKIMNHKERF QFPTQVTDVS ENAKDLIRRL 
       331        341        351        361 
ICSREHRLGQ NGIEDFKKHP FFSGIDWDNI RNCEAPYIPE 
       371        381        391        401 
VSSPTDTSNF DVDddclkns etmpppthta fSGHHLPFVG 
       411        421          - 
FTYTSSCVLS DRSCLRvtag ptsaenlyfq shhhhhh
Lower-case residues are disordered in structure.
Mutations: D254G
Phosphorylation: None