6QA4

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 1.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in HRZ HRZ HRZ HRZ Allosteric Type1 Allosteric Type3 11 - 357 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         2         12         22         32 
mahhhhhhma aaaaagagPE MVRGQVFDVG PRYTNLSYIG 
        42         52         62         72 
EGayGMVCSA YDNVNKVRVA IKKISPFEHQ TYCQRTLREI 
        82         92        102        112 
KILLRFRHEN IIGINDIIRA PTIEQMKDVY IVQDLMETDL 
       122        132        142        152 
YKLLKTQHLS NDHICYFLYQ ILRGLKYIHS ANVLHRDLKP 
       162        172        182        192 
SNLLLNTTCD LKICDFGLAR VADPDHDHTG FLTEYVATRW 
       202        212        222        232 
YRAPEIMLNS KGYTKSIDIW SVGCILAEML SNRPIFPGKH 
       242        252        262        272 
YLDQLNHILG ILGSPSQEDL NCIINLKARN YLLSLPHKNK 
       282        292        302        312 
VPWNRLFPNA DSKALDLLDK MLTFNPHKRI EVEQALAHPY 
       322        332        342        352 
LEQYYDPSDE PIAEAPFKfd melddlPKEK LKELIFEETA 

RFQPGyrs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None