Protein kinases in complex with IRG

Total number of genes: 1
Total number of chains: 10
Spatial Dihedral Chains Representative
DFGin BLBplus 1 4EH2A
DFGin None 2 4EH4A
DFGinter None 2 4EHVA
DFGout None 1 4EH8A
None None 4 4EH3A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH2A 2.0 Inactive DFGin BLBplus in-in none-out IRG 0OK Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4DLIA 1.91 Inactive DFGin None in-in none-out IRG IRG Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH4A 2.5 Inactive DFGin None in-in none-out IRG 0OL Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A 2.1 Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA 1.6 Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A 2.2 Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH5A 2.0 Inactive None None in-in none-out IRG 0OM Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH6A 2.1 Inactive None None in-in none-out IRG 0ON Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH7A 2.1 Inactive None None in-in none-out IRG 0OO Allosteric Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH3A 2.4 Inactive None None in-out none-out NAR IRG Type1 Allosteric

Protein kinases in complex with IRG

Total number of genes: 1
Total number of chains: 10
Spatial Dihedral Chains Representative
DFGin BLBplus 1 4EH2A
DFGin None 2 4EH4A
DFGinter None 2 4EHVA
DFGout None 1 4EH8A
None None 4 4EH3A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH2A 2.0 Inactive DFGin BLBplus in-in none-out IRG 0OK Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4DLIA 1.91 Inactive DFGin None in-in none-out IRG IRG Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH4A 2.5 Inactive DFGin None in-in none-out IRG 0OL Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A 2.1 Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA 1.6 Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A 2.2 Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH5A 2.0 Inactive None None in-in none-out IRG 0OM Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH6A 2.1 Inactive None None in-in none-out IRG 0ON Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH7A 2.1 Inactive None None in-in none-out IRG 0OO Allosteric Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH3A 2.4 Inactive None None in-out none-out NAR IRG Type1 Allosteric

Protein kinases in complex with IRG

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type