MAPKAPK2 (MAP kinase-activated protein kinase 2)

Group: CAMK
Uniprot: MAPK2_HUMAN
Domain boundary: 63 - 325


Total number of chains: 117
Spatial Dihedral Chains Representative
DFGin BLAminus 105 AF-P49137-K1A
DFGin ABAminus 12 8XU4B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
8XU4A 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 351 S216G None 12
8XU4B 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 351 S216G None 11
8XU4C 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 48 - 351 S216G None 11
8XU4D 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 349 S216G None 11
8XU4E 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 353 S216G None 8
8XU4F 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 353 S216G None 11
8XU4G 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 348 S216G None 9
8XU4H 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 358 S216G None 10
8XU4I 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 347 S216G None 14
8XU4J 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 350 S216G None 15
8XU4K 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 348 S216G None 11
8XU4L 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 354 S216G None 13
AF-P49137-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 55 - 333 None None 0
3R2BC 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BD 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BE 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BF 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BG 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BH 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BI 2.9 None DFGin BLAminus in-none in-none No_ligand No_ligand 47 - 345 None None 11
3R2BJ 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BK 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
3R2BL 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
2PZYD 2.9 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 43 - 342 None None 8
3KC3G 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 43 - 342 None None 14
2JBPJ 3.31 None DFGin BLAminus in-in in-none No_ligand No_ligand 48 - 328 None None 18
4TYHA 3.0 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 400 None None 0
2OZAA 2.7 Inactive DFGin BLAminus out-in in-out No_ligand No_ligand 51 - 390 None None 0
6TCAA 3.7 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 399 None None 0
6TCAC 3.7 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 397 None None 0
6TCAE 3.7 None DFGin BLAminus out-none in-out No_ligand No_ligand 51 - 394 None None 0
6TCAG 3.7 None DFGin BLAminus out-none in-out No_ligand No_ligand 51 - 397 None None 0
8XX1A 2.55 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 364 None None 17
1KWPA 2.8 None DFGin BLAminus out-out in-none No_ligand No_ligand 46 - 385 None None 17
1KWPB 2.8 None DFGin BLAminus out-out in-none No_ligand No_ligand 44 - 378 None None 17
2ONLC 4.0 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 46 - 393 None None 0
2ONLD 4.0 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 46 - 393 None None 0
3R2BA 2.9 None DFGin BLAminus in-in in-none 05B Type1 47 - 345 None None 11
3R2BB 2.9 None DFGin BLAminus in-in in-none 05B Type1 47 - 345 None None 11
3R2YA 3.0 None DFGin BLAminus in-in in-none P4O Type1 46 - 345 None None 18
3R30A 3.2 None DFGin BLAminus in-in in-none CD2 Type1 46 - 345 None None 16
2PZYA 2.9 None DFGin BLAminus in-in in-none B18 Type1 42 - 346 None None 11
2PZYB 2.9 None DFGin BLAminus in-in in-none B18 Type1 44 - 345 None None 11
2PZYC 2.9 None DFGin BLAminus in-in in-none STU Type1 42 - 359 None None 11
3KC3A 2.9 None DFGin BLAminus in-in in-none MK2 Type1 43 - 347 None None 11
3KC3B 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 349 None None 11
3KC3C 2.9 None DFGin BLAminus in-in in-none MK2 Type1 41 - 345 None None 12
3KC3D 2.9 None DFGin BLAminus in-in in-none MK2 Type1 46 - 342 None None 15
3KC3E 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 345 None None 11
3KC3F 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 350 None None 11
3KC3H 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 350 None None 11
3KC3I 2.9 None DFGin BLAminus in-in in-none MK2 Type1 45 - 356 None None 13
3KC3J 2.9 None DFGin BLAminus in-in in-none MK2 Type1 43 - 348 None None 9
3KC3K 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 345 None None 14
3KC3L 2.9 None DFGin BLAminus in-in in-none MK2 Type1 42 - 348 None None 11
3WI6A 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
3WI6B 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
3WI6C 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
3WI6D 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
3WI6E 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
3WI6F 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
3FPMA 3.3 None DFGin BLAminus out-out in-none 793 Type1 44 - 345 None None 9
2P3GX 3.8 None DFGin BLAminus out-out in-none F10 Type1 45 - 364 None None 17
3FYJX 3.8 None DFGin BLAminus out-out in-none B97 Type1 45 - 364 None None 17
3FYKX 3.5 None DFGin BLAminus out-out in-none B98 Type1 45 - 364 None None 17
7NRYX 3.8 None DFGin BLAminus out-out in-none B97 Type1 45 - 366 None None 17
2JBOA 3.1 Inactive DFGin BLAminus in-in in-out P4O Type1 44 - 347 None None 8
2JBPA 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 15
2JBPB 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
2JBPC 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
2JBPD 3.31 None DFGin BLAminus in-in in-none P4O Type1 47 - 350 None None 11
2JBPE 3.31 None DFGin BLAminus in-in in-none P4O Type1 44 - 345 None None 11
2JBPF 3.31 None DFGin BLAminus in-in in-none P4O Type1 45 - 350 None None 11
2JBPG 3.31 None DFGin BLAminus in-in in-none P4O Type1 45 - 350 None None 10
2JBPH 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 347 None None 11
2JBPI 3.31 None DFGin BLAminus in-in in-none P4O Type1 45 - 350 None None 11
2JBPK 3.31 None DFGin BLAminus in-in in-none P4O Type1 47 - 345 None None 19
2JBPL 3.31 None DFGin BLAminus in-out in-none P4O Type1 44 - 345 None None 18
3GOKA 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 13
3GOKB 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKC 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKD 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 15
3GOKE 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKF 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKG 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 12
3GOKH 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKI 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKJ 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 15
3GOKK 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3GOKL 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
3KA0A 2.9 None DFGin BLAminus in-in in-none MK3 Type1 47 - 364 T222E None 19
1NXKA 2.7 None DFGin BLAminus in-in in-none STU Type1 42 - 345 None None 11
1NXKB 2.7 None DFGin BLAminus in-in in-none STU Type1 44 - 345 None None 11
1NXKC 2.7 None DFGin BLAminus in-in in-none STU Type1 41 - 357 None None 11
1NXKD 2.7 Inactive DFGin BLAminus in-in in-out STU Type1 43 - 342 None None 8
1NY3A 3.0 None DFGin BLAminus out-out in-none ADP Type1 46 - 345 None None 9
3KGAA 2.55 None DFGin BLAminus in-in in-none LX9 Type1 47 - 364 P237G None 0
3M2WA 2.41 None DFGin BLAminus in-in in-none L8I Type1 47 - 364 P237G None 0
3M42A 2.68 None DFGin BLAminus in-in in-none HGF Type1 47 - 364 P237G None 0
3A2CA 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 47 - 344 None None 13
3A2CB 2.9 None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric 47 - 345 None None 13
3A2CC 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 342 None None 12
3A2CD 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 13
3A2CE 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 12
3A2CF 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 47 - 345 None None 12
3A2CG 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 342 None None 12
3A2CH 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 47 - 343 None None 12
3A2CI 2.9 None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric 48 - 343 None None 12
3A2CJ 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 343 None None 12
3A2CK 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 13
3A2CL 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 12
6T8XA 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 44 - 330 T222E,T334E None 8
6T8XB 2.81 None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric 45 - 329 T222E,T334E None 9
6T8XC 2.81 None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric 44 - 329 T222E,T334E None 10
6T8XD 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 44 - 331 T222E,T334E None 8
6T8XE 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 45 - 329 T222E,T334E None 8
6T8XF 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 45 - 329 T222E,T334E None 9

MAPKAPK2 (MAP kinase-activated protein kinase 2)

Group: CAMK
Total number of chains: 117
Spatial Dihedral Chains Representative
DFGin BLAminus 105 AF-P49137-K1A
DFGin ABAminus 12 8XU4B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens MAPK2_HUMAN 8XU4A 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 351 S216G None 12
Homo sapiens MAPK2_HUMAN 8XU4B 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 351 S216G None 11
Homo sapiens MAPK2_HUMAN 8XU4C 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 48 - 351 S216G None 11
Homo sapiens MAPK2_HUMAN 8XU4D 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 349 S216G None 11
Homo sapiens MAPK2_HUMAN 8XU4E 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 353 S216G None 8
Homo sapiens MAPK2_HUMAN 8XU4F 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 353 S216G None 11
Homo sapiens MAPK2_HUMAN 8XU4G 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 348 S216G None 9
Homo sapiens MAPK2_HUMAN 8XU4H 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 358 S216G None 10
Homo sapiens MAPK2_HUMAN 8XU4I 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 347 S216G None 14
Homo sapiens MAPK2_HUMAN 8XU4J 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 350 S216G None 15
Homo sapiens MAPK2_HUMAN 8XU4K 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 348 S216G None 11
Homo sapiens MAPK2_HUMAN 8XU4L 3.4 Inactive DFGin ABAminus in-in in-none No_ligand No_ligand 47 - 354 S216G None 13
Homo sapiens MAPK2_HUMAN AF-P49137-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 55 - 333 None None 0
Homo sapiens MAPK2_HUMAN 3R2BC 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BD 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BE 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BF 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BG 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BH 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BI 2.9 None DFGin BLAminus in-none in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BJ 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BK 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BL 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 2PZYD 2.9 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 43 - 342 None None 8
Homo sapiens MAPK2_HUMAN 3KC3G 2.9 None DFGin BLAminus in-in in-none No_ligand No_ligand 43 - 342 None None 14
Homo sapiens MAPK2_HUMAN 2JBPJ 3.31 None DFGin BLAminus in-in in-none No_ligand No_ligand 48 - 328 None None 18
Homo sapiens MAPK2_HUMAN 4TYHA 3.0 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 400 None None 0
Homo sapiens MAPK2_HUMAN 2OZAA 2.7 Inactive DFGin BLAminus out-in in-out No_ligand No_ligand 51 - 390 None None 0
Homo sapiens MAPK2_HUMAN 6TCAA 3.7 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 399 None None 0
Homo sapiens MAPK2_HUMAN 6TCAC 3.7 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 51 - 397 None None 0
Homo sapiens MAPK2_HUMAN 6TCAE 3.7 None DFGin BLAminus out-none in-out No_ligand No_ligand 51 - 394 None None 0
Homo sapiens MAPK2_HUMAN 6TCAG 3.7 None DFGin BLAminus out-none in-out No_ligand No_ligand 51 - 397 None None 0
Homo sapiens MAPK2_HUMAN 8XX1A 2.55 None DFGin BLAminus in-in in-none No_ligand No_ligand 47 - 364 None None 17
Homo sapiens MAPK2_HUMAN 1KWPA 2.8 None DFGin BLAminus out-out in-none No_ligand No_ligand 46 - 385 None None 17
Homo sapiens MAPK2_HUMAN 1KWPB 2.8 None DFGin BLAminus out-out in-none No_ligand No_ligand 44 - 378 None None 17
Homo sapiens MAPK2_HUMAN 2ONLC 4.0 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 46 - 393 None None 0
Homo sapiens MAPK2_HUMAN 2ONLD 4.0 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 46 - 393 None None 0
Homo sapiens MAPK2_HUMAN 3R2BA 2.9 None DFGin BLAminus in-in in-none 05B Type1 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2BB 2.9 None DFGin BLAminus in-in in-none 05B Type1 47 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3R2YA 3.0 None DFGin BLAminus in-in in-none P4O Type1 46 - 345 None None 18
Homo sapiens MAPK2_HUMAN 3R30A 3.2 None DFGin BLAminus in-in in-none CD2 Type1 46 - 345 None None 16
Homo sapiens MAPK2_HUMAN 2PZYA 2.9 None DFGin BLAminus in-in in-none B18 Type1 42 - 346 None None 11
Homo sapiens MAPK2_HUMAN 2PZYB 2.9 None DFGin BLAminus in-in in-none B18 Type1 44 - 345 None None 11
Homo sapiens MAPK2_HUMAN 2PZYC 2.9 None DFGin BLAminus in-in in-none STU Type1 42 - 359 None None 11
Homo sapiens MAPK2_HUMAN 3KC3A 2.9 None DFGin BLAminus in-in in-none MK2 Type1 43 - 347 None None 11
Homo sapiens MAPK2_HUMAN 3KC3B 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 349 None None 11
Homo sapiens MAPK2_HUMAN 3KC3C 2.9 None DFGin BLAminus in-in in-none MK2 Type1 41 - 345 None None 12
Homo sapiens MAPK2_HUMAN 3KC3D 2.9 None DFGin BLAminus in-in in-none MK2 Type1 46 - 342 None None 15
Homo sapiens MAPK2_HUMAN 3KC3E 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 345 None None 11
Homo sapiens MAPK2_HUMAN 3KC3F 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3KC3H 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3KC3I 2.9 None DFGin BLAminus in-in in-none MK2 Type1 45 - 356 None None 13
Homo sapiens MAPK2_HUMAN 3KC3J 2.9 None DFGin BLAminus in-in in-none MK2 Type1 43 - 348 None None 9
Homo sapiens MAPK2_HUMAN 3KC3K 2.9 None DFGin BLAminus in-in in-none MK2 Type1 44 - 345 None None 14
Homo sapiens MAPK2_HUMAN 3KC3L 2.9 None DFGin BLAminus in-in in-none MK2 Type1 42 - 348 None None 11
Homo sapiens MAPK2_HUMAN 3WI6A 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
Homo sapiens MAPK2_HUMAN 3WI6B 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
Homo sapiens MAPK2_HUMAN 3WI6C 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
Homo sapiens MAPK2_HUMAN 3WI6D 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
Homo sapiens MAPK2_HUMAN 3WI6E 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
Homo sapiens MAPK2_HUMAN 3WI6F 2.99 None DFGin BLAminus out-out in-none YRZ Type1 46 - 347 None None 10
Homo sapiens MAPK2_HUMAN 3FPMA 3.3 None DFGin BLAminus out-out in-none 793 Type1 44 - 345 None None 9
Homo sapiens MAPK2_HUMAN 2P3GX 3.8 None DFGin BLAminus out-out in-none F10 Type1 45 - 364 None None 17
Homo sapiens MAPK2_HUMAN 3FYJX 3.8 None DFGin BLAminus out-out in-none B97 Type1 45 - 364 None None 17
Homo sapiens MAPK2_HUMAN 3FYKX 3.5 None DFGin BLAminus out-out in-none B98 Type1 45 - 364 None None 17
Homo sapiens MAPK2_HUMAN 7NRYX 3.8 None DFGin BLAminus out-out in-none B97 Type1 45 - 366 None None 17
Homo sapiens MAPK2_HUMAN 2JBOA 3.1 Inactive DFGin BLAminus in-in in-out P4O Type1 44 - 347 None None 8
Homo sapiens MAPK2_HUMAN 2JBPA 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 15
Homo sapiens MAPK2_HUMAN 2JBPB 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 2JBPC 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 2JBPD 3.31 None DFGin BLAminus in-in in-none P4O Type1 47 - 350 None None 11
Homo sapiens MAPK2_HUMAN 2JBPE 3.31 None DFGin BLAminus in-in in-none P4O Type1 44 - 345 None None 11
Homo sapiens MAPK2_HUMAN 2JBPF 3.31 None DFGin BLAminus in-in in-none P4O Type1 45 - 350 None None 11
Homo sapiens MAPK2_HUMAN 2JBPG 3.31 None DFGin BLAminus in-in in-none P4O Type1 45 - 350 None None 10
Homo sapiens MAPK2_HUMAN 2JBPH 3.31 None DFGin BLAminus in-in in-none P4O Type1 46 - 347 None None 11
Homo sapiens MAPK2_HUMAN 2JBPI 3.31 None DFGin BLAminus in-in in-none P4O Type1 45 - 350 None None 11
Homo sapiens MAPK2_HUMAN 2JBPK 3.31 None DFGin BLAminus in-in in-none P4O Type1 47 - 345 None None 19
Homo sapiens MAPK2_HUMAN 2JBPL 3.31 None DFGin BLAminus in-out in-none P4O Type1 44 - 345 None None 18
Homo sapiens MAPK2_HUMAN 3GOKA 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 13
Homo sapiens MAPK2_HUMAN 3GOKB 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKC 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKD 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 15
Homo sapiens MAPK2_HUMAN 3GOKE 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKF 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKG 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 12
Homo sapiens MAPK2_HUMAN 3GOKH 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKI 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKJ 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 15
Homo sapiens MAPK2_HUMAN 3GOKK 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3GOKL 3.2 None DFGin BLAminus in-in in-none P4O Type1 46 - 350 None None 11
Homo sapiens MAPK2_HUMAN 3KA0A 2.9 None DFGin BLAminus in-in in-none MK3 Type1 47 - 364 T222E None 19
Homo sapiens MAPK2_HUMAN 1NXKA 2.7 None DFGin BLAminus in-in in-none STU Type1 42 - 345 None None 11
Homo sapiens MAPK2_HUMAN 1NXKB 2.7 None DFGin BLAminus in-in in-none STU Type1 44 - 345 None None 11
Homo sapiens MAPK2_HUMAN 1NXKC 2.7 None DFGin BLAminus in-in in-none STU Type1 41 - 357 None None 11
Homo sapiens MAPK2_HUMAN 1NXKD 2.7 Inactive DFGin BLAminus in-in in-out STU Type1 43 - 342 None None 8
Homo sapiens MAPK2_HUMAN 1NY3A 3.0 None DFGin BLAminus out-out in-none ADP Type1 46 - 345 None None 9
Homo sapiens MAPK2_HUMAN 3KGAA 2.55 None DFGin BLAminus in-in in-none LX9 Type1 47 - 364 P237G None 0
Homo sapiens MAPK2_HUMAN 3M2WA 2.41 None DFGin BLAminus in-in in-none L8I Type1 47 - 364 P237G None 0
Homo sapiens MAPK2_HUMAN 3M42A 2.68 None DFGin BLAminus in-in in-none HGF Type1 47 - 364 P237G None 0
Homo sapiens MAPK2_HUMAN 3A2CA 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 47 - 344 None None 13
Homo sapiens MAPK2_HUMAN 3A2CB 2.9 None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric 47 - 345 None None 13
Homo sapiens MAPK2_HUMAN 3A2CC 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 342 None None 12
Homo sapiens MAPK2_HUMAN 3A2CD 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 13
Homo sapiens MAPK2_HUMAN 3A2CE 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 12
Homo sapiens MAPK2_HUMAN 3A2CF 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 47 - 345 None None 12
Homo sapiens MAPK2_HUMAN 3A2CG 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 342 None None 12
Homo sapiens MAPK2_HUMAN 3A2CH 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 47 - 343 None None 12
Homo sapiens MAPK2_HUMAN 3A2CI 2.9 None DFGin BLAminus in-out in-none PDY PDY Type1 Allosteric 48 - 343 None None 12
Homo sapiens MAPK2_HUMAN 3A2CJ 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 343 None None 12
Homo sapiens MAPK2_HUMAN 3A2CK 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 13
Homo sapiens MAPK2_HUMAN 3A2CL 2.9 None DFGin BLAminus in-in in-none PDY PDY Type1 Allosteric 48 - 344 None None 12
Homo sapiens MAPK2_HUMAN 6T8XA 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 44 - 330 T222E,T334E None 8
Homo sapiens MAPK2_HUMAN 6T8XB 2.81 None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric 45 - 329 T222E,T334E None 9
Homo sapiens MAPK2_HUMAN 6T8XC 2.81 None DFGin BLAminus in-in in-none B97 MW8 Type1 Allosteric 44 - 329 T222E,T334E None 10
Homo sapiens MAPK2_HUMAN 6T8XD 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 44 - 331 T222E,T334E None 8
Homo sapiens MAPK2_HUMAN 6T8XE 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 45 - 329 T222E,T334E None 8
Homo sapiens MAPK2_HUMAN 6T8XF 2.81 Inactive DFGin BLAminus in-in in-out B97 MW8 Type1 Allosteric 45 - 329 T222E,T334E None 9

MAPKAPK2 (MAP kinase-activated protein kinase 2)

No non-human structures known.