5WP1

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 1.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in B7S BEZ Type1 Allosteric 15 - 357 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        13         23         33         43 
aaaagagpem vRGQVFDVGP RYTNLSYIGE GAYGMVCSAY 
        53         63         73         83 
DNVNKVRVAI KKISPFEHQT YCQRTLREIK ILLRFRHENI 
        93        103        113        123 
IGINDIIRAP TIEQMKDVYI VQDLMETDLY KLLKTQHLSN 
       133        143        153        163 
DHICYFLYQI LRGLKYIHSA NVLHRDLKPS NLLLNTTCDL 
       173        183        193        203 
KICDFGLARV ADPDHDHTGF LTEYVATRWY RAPEIMLNSK 
       213        223        233        243 
GYTKSIDIWS VGCILAEMLS NRPIFPGKHY LDQLNHILGI 
       253        263        273        283 
LGSPSQEDLN CIINLKARNY LLSLPHKNKV PWNRLFPNAD 
       293        303        313        323 
SKALDLLDKM LTFNPHKRIE VEQALAHPYL EQYYDPSDEP 
       333        343        353 
IAEAPFKFDM ELDDLPKEKL KELIFEETAR FQPGyrs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None