7JY4

ALK (ALK tyrosine kinase receptor)
Group: TYR
Uniprot: ALK_HUMAN
Organism: Homo sapiens
Domain boundary: 1116 - 1385
Resolu: 2.42

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-out out-out W47 W47 Allosteric Type1 1096 - 1399 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1094       1104       1114       1124 
gamgstdynp nYCFAGKTSS ISDLKEVPRK NITLIRGLGH 
      1134       1144       1154       1164 
GAFGEVYEGQ VSgmpndpsP LQVAVKTLPE VCSEQDELDF 
      1174       1184       1194       1204 
LMEALIISKF NHQNIVRCIG VSLQSLPRFI LLELMAGGDL 
      1214       1224       1234       1244 
KSFLRETRPR PSQPSSLAML DLLHVARDIA CGCQYLEENH 
      1254       1264       1274       1284 
FIHRDIAARN CLLTCPGPGR VAKIGDFGMA RDIYrasyyr 
      1294       1304       1314       1324 
kGGCAMLPVK WMPPEAFMEG IFTSKTDTWS FGVLLWEIFS 
      1334       1344       1354       1364 
LGYMPYPSKS NQEVLEFVTS GGRMDPPKNC PGPVYRIMTQ 
      1374       1384       1394       1404 
CWQHQPEDRP NFAIILERIE YCTQDPDVIN TALPIeygpl 

ve
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None