8FLL

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_HUMAN
Organism: Homo sapiens
Domain boundary: 402 - 653
Resolu: 1.498

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-none out-out Y7W BTB Type1.5_Front Allosteric 395 - 658 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       396        406        416        426 
gmglgygsWE IDPKDLTFLK ELGTGQFGVV KYGKWRGQYD 
       436        446        456        466 
VAIKMIKEGS MSEDEFIEEA KVMMNLSHEK LVQLYGVCTK 
       476        486        496        506 
QRPIFIITEY MANGCLLNYL REMRHRFQTQ QLLEMCKDVC 
       516        526        536        546 
EAMEYLESKQ FLHRDLAARN CLVNDQGVVK VSDFGLSRYV 
       556        566        576        586 
LDDEYTSSVG SKFPVRWSPP EVLMYSKFSS KSDIWAFGVL 
       596        606        616        626 
MWEIYSLGKM PYERFTNSET AEHIAQGLRL YRPHLASEKV 
       636        646        656 
YTIMYSCWHE KADERPTFKI LLSNILDVMD EEs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None