MAPK14 (Mitogen-activated protein kinase 14)

Group: CMGC
Uniprot: MK14_HUMAN
Domain boundary: 24 - 308


Total number of chains: 265
Spatial Dihedral Chains Representative
DFGin BLAminus 8 AF-Q16539-K1A
DFGin BLAplus 3 3HUBA
DFGin BLBminus 34 5XYYA
DFGin BLBplus 78 3GC7A
DFGin None 40 1WBOA
DFGinter None 12 5WJJA
DFGout BBAminus 44 3KQ7A
DFGout None 27 1WBSA
None None 19 8A8MA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q16539-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 16 - 316 None None 0
3HVCA 2.1 None DFGin BLAminus in-in none-none No_ligand No_ligand 5 - 352 None None 14
1WBWA 2.41 Inactive DFGin BLAminus in-in out-out LI4 Type1 4 - 355 None None 0
6ZQSA 1.95 Inactive DFGin BLAminus out-out in-in 3FF Type1 4 - 353 None X180,X182 0
6TCAB 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 6 - 354 None X180,X182 0
6TCAD 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 4 - 353 None X180,X182 0
6TCAF 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 6 - 353 None X180,X182 0
6TCAH 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 4 - 353 None X180,X182 0
3HUBA 2.25 Inactive DFGin BLAplus in-in none-none 469 Type1 4 - 352 C119S,C162S,A172C,F327L None 14
3UVPA 2.4 Inactive DFGin BLAplus in-in none-out 048 Type1 5 - 352 None None 11
3UVQA 2.2 Inactive DFGin BLAplus in-in none-none FS8 Type1 5 - 353 None None 13
5N68A 1.85 Inactive DFGin BLBminus in-in none-none 8OK Allosteric 4 - 351 None None 14
2Y8OA 1.95 Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 4 - 353 C162S None 11
1R3CA 2.0 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 C162S None 0
2LGCA 999.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand 2 - 354 None None 0
5ETAA 2.8 Inactive DFGin BLBminus out-out none-none No_ligand No_ligand 4 - 354 None None 15
5ETAB 2.8 Inactive DFGin BLBminus out-out none-none No_ligand No_ligand 4 - 353 None None 15
1R39A 2.3 Inactive DFGin BLBminus in-out none-out No_ligand No_ligand 4 - 351 None None 3
2OKRA 2.0 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 None None 10
2OKRD 2.0 Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 5 - 355 None None 12
2ONLA 4.0 Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 4 - 352 None None 11
2ONLB 4.0 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 None None 10
5ETFA 2.4 Inactive DFGin BLBminus out-none none-out No_ligand No_ligand 4 - 353 None None 12
1BMKA 2.4 Inactive DFGin BLBminus in-out out-out SB5 Type1 4 - 354 None None 0
3MW1A 2.8 Inactive DFGin BLBminus in-in none-out MIH Type1 4 - 352 None None 2
1DI9A 2.6 Inactive DFGin BLBminus in-in out-out MSQ Type1 4 - 351 None None 0
1W7HA 2.214 Inactive DFGin BLBminus in-in out-out 3IP Type1 4 - 355 None None 0
1W84A 2.2 Inactive DFGin BLBminus in-in out-out L12 Type1 4 - 355 None None 0
2ZB0A 2.1 Inactive DFGin BLBminus in-in out-out GK3 Type1 4 - 352 None None 0
1M7QA 2.4 Inactive DFGin BLBminus in-in out-out DQO Type1 4 - 351 None None 0
1OUKA 2.5 Inactive DFGin BLBminus in-in out-out 084 Type1 4 - 351 None None 0
1OUYA 2.5 Inactive DFGin BLBminus in-in out-out 094 Type1 4 - 353 None None 0
1YQJA 2.0 Inactive DFGin BLBminus in-out out-out 6NP Type1 2 - 352 None None 0
3ZYAA 1.9 Inactive DFGin BLBminus out-in none-out 2A8 Type1 1 - 353 None None 12
1OZ1A 2.1 Inactive DFGin BLBminus in-in out-out FPH Type1 5 - 352 None None 0
3FLQA 1.9 Inactive DFGin BLBminus in-in out-out 891 Type1 4 - 352 None None 0
3FMJA 2.0 Inactive DFGin BLBminus in-in out-out FMJ Type1 4 - 352 None None 2
3FSFA 2.1 Inactive DFGin BLBminus in-in none-out FSS Type1 5 - 352 None None 3
1A9UA 2.5 Inactive DFGin BLBminus in-in out-out SB2 Type1 4 - 354 None None 0
1BL6A 2.5 Inactive DFGin BLBminus in-in out-out SB6 Type1 4 - 354 None None 0
1BL7A 2.5 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 354 None None 0
3MPAA 2.1 Inactive DFGin BLBminus in-in none-none SB2 Type1 5 - 352 D168G None 14
2ZB1A 2.5 Inactive DFGin BLBminus in-in none-out GK4 Type1.5_Back 4 - 352 None None 2
5XYXA 2.61 Inactive DFGin BLBminus in-in none-out FTZ Type1.5_Back 4 - 353 None None 3
5XYYA 1.7 Inactive DFGin BLBminus in-in out-out P0F Type1.5_Back 4 - 353 None None 0
3NEWA 2.51 Inactive DFGin BLBplus in-in none-none 3NE Allosteric 5 - 352 C162S None 12
4EH2A 2.0 Inactive DFGin BLBplus in-in none-out IRG 0OK Allosteric Type1 4 - 354 None None 12
3MH2A 2.3 Inactive DFGin BLBplus in-out none-none No_ligand No_ligand 5 - 352 F169Y None 14
5ETIA 2.8 Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 1 - 352 None None 0
3FI4A 2.2 Inactive DFGin BLBplus in-in none-out FI4 Type1 4 - 352 R57K None 3
3FKOA 2.0 Inactive DFGin BLBplus in-in none-out FKO Type1 5 - 352 R57K None 3
3FLNC 1.9 Inactive DFGin BLBplus in-in none-out 3FN Type1 3 - 352 R57K None 3
6OHDA 2.5 Inactive DFGin BLBplus in-in out-out MKP Type1 4 - 352 None None 10
1OVEA 2.1 Inactive DFGin BLBplus in-in out-out 358 Type1 4 - 352 C162S None 0
3GC7A 1.8 Inactive DFGin BLBplus in-in out-out B45 Type1 4 - 352 C162S None 0
3S3IA 1.8 Inactive DFGin BLBplus in-in out-out CQ0 Type1 4 - 352 None None 0
1ZZLA 2.0 Inactive DFGin BLBplus in-in out-out TZY Type1 4 - 354 None None 0
2YIXA 2.3 Inactive DFGin BLBplus in-in out-out YIX Type1 4 - 354 None None 0
3HRBA 2.2 Inactive DFGin BLBplus in-in out-out I39 Type1 4 - 352 None None 0
1ZYJA 2.0 Inactive DFGin BLBplus in-in none-none BI5 Type1 5 - 352 None None 13
1ZZ2A 2.0 Inactive DFGin BLBplus in-in none-out B11 Type1 5 - 352 None None 11
2ZAZA 1.8 Inactive DFGin BLBplus in-in out-out GK1 Type1 4 - 352 None None 0
3D7ZA 2.1 Inactive DFGin BLBplus in-in out-out GK5 Type1 4 - 352 None None 0
3IPHA 2.1 Inactive DFGin BLBplus in-in none-out G11 Type1 4 - 352 None None 2
3KF7A 2.0 Inactive DFGin BLBplus in-in none-out L9G Type1 5 - 352 None None 11
3RINA 2.2 Inactive DFGin BLBplus in-in out-out I2O Type1 4 - 352 None None 0
5MTXA 1.8 Inactive DFGin BLBplus in-in none-none FJI Type1 5 - 352 None None 13
5MTYA 2.31 Inactive DFGin BLBplus in-in none-none HB9 Type1 5 - 352 None None 14
5TBEA 2.44 Inactive DFGin BLBplus in-in none-none 78L Type1 5 - 353 None None 13
5TCOA 2.1 Inactive DFGin BLBplus in-in none-none 79Q Type1 6 - 352 None None 13
6M9LA 2.45 Inactive DFGin BLBplus in-in none-none J9G Type1 5 - 352 None None 14
3DS6A 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 6
3DS6B 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 6
3DS6C 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 0
3DS6D 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 0
3GFEA 2.1 Inactive DFGin BLBplus in-in out-out P37 Type1 1 - 352 None None 0
3ITZA 2.25 Inactive DFGin BLBplus in-in out-out P66 Type1 1 - 353 None None 0
3LHJA 3.31 Inactive DFGin BLBplus in-in none-out LHJ Type1 5 - 352 None None 7
3U8WA 2.15 Inactive DFGin BLBplus in-in out-out 09J Type1 4 - 352 None None 0
2BALA 2.1 Inactive DFGin BLBplus in-in none-out PQA Type1 5 - 353 None None 11
4AA4A 2.3 Inactive DFGin BLBplus in-in out-out QC0 Type1 5 - 355 None None 0
4AA5A 2.38 Inactive DFGin BLBplus in-in out-out NQB Type1 5 - 352 None None 3
4AACA 2.5 Inactive DFGin BLBplus in-in out-out AAV Type1 5 - 359 None None 0
2QD9A 1.7 Inactive DFGin BLBplus in-in none-none LGF Type1 5 - 352 None None 13
3MVLA 2.8 Inactive DFGin BLBplus in-in out-none 38P Type1 5 - 353 None None 10
3MVLB 2.8 Inactive DFGin BLBplus in-in out-none 38P Type1 5 - 353 None None 10
3MVMA 2.0 Inactive DFGin BLBplus in-in out-none 39P Type1 4 - 352 None None 9
3MVMB 2.0 Inactive DFGin BLBplus in-in out-none 39P Type1 5 - 351 None None 11
3NWWA 2.09 Inactive DFGin BLBplus in-in out-none 3NW Type1 5 - 353 None None 10
3S4QA 2.27 Inactive DFGin BLBplus in-in none-out NK0 Type1 4 - 352 None None 11
4KINA 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 5 - 352 None None 8
4KINB 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 4 - 352 None None 8
4KINC 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 4 - 352 None None 9
4KIND 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 4 - 354 None None 9
4KIPA 2.27 Inactive DFGin BLBplus in-in none-out 1R9 Type1 5 - 352 None None 11
4KIPB 2.27 Inactive DFGin BLBplus in-in none-out 1R9 Type1 5 - 352 None None 10
4KIQA 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
4KIQB 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
4KIQC 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
4KIQD 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
3FKLA 2.0 Inactive DFGin BLBplus in-in none-out FKL Type1 4 - 352 None None 5
3FKNA 2.0 Inactive DFGin BLBplus in-in none-out FKN Type1 4 - 352 None None 3
3FL4A 1.8 Inactive DFGin BLBplus in-in none-out FL4 Type1 4 - 352 None None 4
3FLSA 2.3 Inactive DFGin BLBplus in-in none-out FLS Type1 4 - 352 None None 2
3FLWA 2.1 Inactive DFGin BLBplus in-in none-out FLW Type1 4 - 352 None None 3
3FLYA 1.8 Inactive DFGin BLBplus in-in none-out FLY Type1 4 - 352 None None 2
3FLZA 2.23 Inactive DFGin BLBplus in-in none-out FLZ Type1 4 - 352 None None 2
3FMHA 1.9 Inactive DFGin BLBplus in-in none-out 533 Type1 4 - 352 None None 2
3FMKA 1.7 Inactive DFGin BLBplus in-in none-out FMK Type1 4 - 352 None None 3
3FMMA 2.0 Inactive DFGin BLBplus in-in none-out XI2 Type1 4 - 352 None None 3
3FMNA 1.9 Inactive DFGin BLBplus in-in none-out 530 Type1 4 - 352 None None 4
3E92A 2.0 Inactive DFGin BLBplus in-in none-out G6A Type1 3 - 352 None None 1
3MPTA 1.89 Inactive DFGin BLBplus in-in none-out 1GK Type1 4 - 352 None None 2
3DT1A 2.8 Inactive DFGin BLBplus in-in out-out P40 Type1 1 - 352 None None 0
4F9YA 1.85 Inactive DFGin BLBplus in-in none-out LM3 Type1 5 - 353 None None 10
3HL7A 1.88 Inactive DFGin BLBplus in-in none-out I47 I46 Type1 Allosteric 6 - 352 None None 11
3ROCA 1.7 Inactive DFGin BLBplus in-out none-out 29A 29B Type1 Allosteric 5 - 352 None None 11
3HLLA 1.95 Inactive DFGin BLBplus in-out none-out I45 I46 PO2 Type1 Allosteric Allosteric 5 - 352 None None 11
2I0HA 2.0 Inactive DFGin BLBplus in-in out-out 222 222 Type1 Type1 4 - 352 C162S None 0
2RG5A 2.4 Inactive DFGin BLBplus in-in out-none 279 Type1.5_Back 4 - 351 None None 11
3BX5A 2.4 Inactive DFGin BLBplus in-in out-none 304 Type1.5_Back 5 - 352 None None 10
3L8XA 2.4 Inactive DFGin BLBplus in-in out-out N4D Type1.5_Back 4 - 352 None None 10
2RG6A 1.72 Inactive DFGin BLBplus in-in out-out 287 287 Type1.5_Back Allosteric 4 - 352 None None 10
4E6AA 2.09 Inactive DFGin None in-in none-none 0O9 Allosteric 4 - 351 None None 16
4E6CA 2.39 Inactive DFGin None in-in none-none 0O8 Allosteric 4 - 351 None None 15
5N67A 1.9 Inactive DFGin None in-in none-out 8ON Allosteric 5 - 353 None None 14
4DLIA 1.91 Inactive DFGin None in-in none-out IRG IRG Allosteric Allosteric 5 - 354 None None 12
4EH4A 2.5 Inactive DFGin None in-in none-out IRG 0OL Allosteric Type1 4 - 354 None None 10
3C5UA 2.8 Inactive DFGin None in-in none-out P41 P41 Allosteric Type1 4 - 352 None None 11
4E5AX 1.87 Inactive DFGin None in-in none-out No_ligand No_ligand 3 - 353 W197A None 14
3OD6X 2.682 Inactive DFGin None in-in in-out No_ligand No_ligand 4 - 352 Y323T None 0
3OEFX 1.6 Inactive DFGin None in-in out-none No_ligand No_ligand 5 - 352 Y323F None 11
3ODYX 2.2 Inactive DFGin None out-out none-out No_ligand No_ligand 4 - 353 Y323Q None 10
3MGYA 2.1 Inactive DFGin None in-in none-none No_ligand No_ligand 5 - 352 None None 15
4E5BA 2.0 Inactive DFGin None in-in none-none No_ligand No_ligand 4 - 351 None None 16
3ODZX 2.3 Inactive DFGin None out-out none-out No_ligand No_ligand 4 - 353 Y323R None 10
5ETCA 2.422 Inactive DFGin None in-out out-out No_ligand No_ligand 1 - 352 None None 0
1WFCA 2.3 Inactive DFGin None in-out none-out No_ligand No_ligand 5 - 351 None None 5
3MH0A 2.0 Inactive DFGin None in-in none-none No_ligand No_ligand 5 - 352 F169A None 12
3IW6A 2.1 Inactive DFGin None in-in none-out PP0 Type1 4 - 353 C119S,C162S,A172C,F327L None 11
3IW7A 2.4 Inactive DFGin None in-in none-out IPK Type1 4 - 352 C119S,C162S,A172C,F327L None 12
2BAQA 2.8 Inactive DFGin None in-in none-out PQB Type1 5 - 351 V30I None 9
1WBOA 2.16 Inactive DFGin None in-in out-out 2CH Type1 4 - 354 None None 0
5OMGA 2.0 Inactive DFGin None in-in none-out 9Y8 Type1 4 - 353 None None 10
3QUDA 2.0 Inactive DFGin None in-in out-out N3F Type1 4 - 354 None None 6
3QUEA 2.7 Inactive DFGin None in-in out-out 3FF Type1 5 - 353 None None 6
3ZSIA 2.4 Inactive DFGin None in-in none-none 52P Type1 6 - 352 None None 13
3FC1X 2.4 Inactive DFGin None in-in none-out 52P Type1 5 - 353 None None 8
3BV2A 2.4 Inactive DFGin None in-in out-out P38 Type1 5 - 351 None None 10
3OCGA 2.21 Inactive DFGin None in-in none-none OCG Type1 4 - 352 None None 13
2GFSA 1.752 Inactive DFGin None in-in none-out PQB Type1 5 - 352 None None 4
3FMLA 2.1 Inactive DFGin None in-in out-out FML Type1 4 - 352 None None 1
3FSKA 2.0 Inactive DFGin None in-in none-out RO6 Type1 5 - 352 None None 6
3HA8A 2.48 Inactive DFGin None in-out none-out 5JZ Type1 4 - 352 None None 7
4F9WA 2.0 Inactive DFGin None in-out none-out LM4 Type1 5 - 352 None None 12
4FA2A 2.0 Inactive DFGin None in-in none-out SB0 Type1 4 - 353 None None 11
4ZTHA 2.15 Inactive DFGin None in-in none-out VVT Type1 4 - 353 None None 11
3O8PA 2.1 Inactive DFGin None in-out none-out BMU Type1 5 - 351 D168G None 11
3OBGA 2.8 Inactive DFGin None in-in none-none SB2 Type1 5 - 352 F169G None 12
4EWQA 2.1 Inactive DFGin None in-in out-out MWL MWL Type1 Allosteric 5 - 353 None X180 2
4R3CA 2.06 Inactive DFGin None in-out none-out 3GF 3GF Type1 Allosteric 4 - 352 None None 13
3HP2A 2.15 Inactive DFGin None in-in none-out P36 I46 I46 Type1 Allosteric Allosteric 4 - 355 None None 11
3HP5A 2.3 Inactive DFGin None in-in none-out 52P I46 I46 Type1 Allosteric Allosteric 6 - 352 None None 12
4EH9A 2.1 Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3 5 - 354 None None 11
3GCPA 2.25 Inactive DFGinter None in-in none-none SB2 Type1 4 - 352 C119S,C162S,A172C,F327L None 12
5WJJA 1.6 Inactive DFGinter None in-in out-out AQY Type1 5 - 352 None None 6
6ANLA 2.0 Inactive DFGinter None in-in none-out T75 Type1 4 - 352 C119S,C162S None 11
5ML5A 1.9 Inactive DFGinter None in-in none-none 1VI Type1 5 - 352 None None 14
3HUCA 1.8 Inactive DFGinter None in-in none-out G97 Type1 4 - 352 None None 12
3ZS5A 1.6 Inactive DFGinter None in-in none-out SB2 Type1 2 - 352 None None 12
3ZSGA 1.89 Inactive DFGinter None in-in none-out T75 Type1 4 - 352 None None 12
6HWTA 1.7 Inactive DFGinter None in-in out-none GXH Type1 5 - 352 None None 11
6HWUA 2.3 Inactive DFGinter None in-in none-out GE5 Type1 5 - 353 None None 11
6HWVA 1.7 Inactive DFGinter None in-in none-none GEW Type1 5 - 352 None None 12
4EHVA 1.6 Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric 5 - 352 None None 11
6QDZA 1.73 Inactive DFGout BBAminus in-in none-out I46 HYK Allosteric Type2 5 - 352 None None 13
6QE1A 1.85 Inactive DFGout BBAminus in-in none-out I46 HYW Allosteric Type2 5 - 352 None None 13
3GCQA 2.0 Inactive DFGout BBAminus in-out none-out 1BU Type2 4 - 355 C119S,C162S,A172C,F327L None 12
3GCSA 2.1 Inactive DFGout BBAminus in-out none-none BAX Type2 5 - 352 C119S,C162S,A172C,F327L None 14
3GCVA 2.3 Inactive DFGout BBAminus in-in none-out SS6 Type2 4 - 353 C119S,C162S,A172C,F327L None 10
3HV3A 2.0 Inactive DFGout BBAminus in-in none-out R49 Type2 4 - 353 C119S,C162S,A172C,F327L None 12
3LFEA 2.3 Inactive DFGout BBAminus in-in none-out Z84 Type2 4 - 353 C119S,C162S,A172C,F327L None 13
3LFFA 1.5 Inactive DFGout BBAminus in-in none-out Z83 Type2 5 - 352 C119S,C162S,A172C,F327L None 13
3PG3A 2.0 Inactive DFGout BBAminus out-out none-out DG7 Type2 4 - 353 C119S,C162S,A172C,F327L None 13
6SFIA 1.6 Inactive DFGout BBAminus in-in out-out LB5 Type2 4 - 353 None None 10
6SFJA 1.95 Inactive DFGout BBAminus in-in out-out LBB Type2 4 - 353 None None 9
6SFOA 1.75 Inactive DFGout BBAminus in-in none-out LBE Type2 5 - 352 None None 12
6ZWPA 1.9 Inactive DFGout BBAminus in-in none-out OE8 Type2 4 - 353 None None 12
3CTQA 1.95 Inactive DFGout BBAminus in-in none-out 337 Type2 5 - 352 None None 12
5MZ3A 2.15 Inactive DFGout BBAminus in-in out-out 8EN Type2 4 - 353 C162S None 0
3HEGA 2.2 Inactive DFGout BBAminus in-in none-out BAX Type2 5 - 352 None None 11
1W83A 2.5 Inactive DFGout BBAminus in-in out-out L11 Type2 4 - 355 None None 0
1WBNA 2.4 Inactive DFGout BBAminus in-in out-out L09 Type2 4 - 355 None None 0
3D83A 1.9 Inactive DFGout BBAminus in-in out-out GK6 Type2 4 - 352 None None 0
3GCUA 2.1 Inactive DFGout BBAminus in-in none-out R48 Type2 4 - 352 None None 10
3GCUB 2.1 Inactive DFGout BBAminus in-in none-out R48 Type2 5 - 352 None None 11
3HV4A 2.6 Inactive DFGout BBAminus in-in none-out L51 Type2 4 - 352 None None 10
3HV4B 2.6 Inactive DFGout BBAminus in-in none-out L51 Type2 5 - 352 None None 10
3HV5A 2.25 Inactive DFGout BBAminus in-in none-out R24 Type2 4 - 352 None None 10
3HV5B 2.25 Inactive DFGout BBAminus in-in none-out R24 Type2 4 - 352 None None 10
3HV6A 1.95 Inactive DFGout BBAminus in-out none-out R39 Type2 4 - 352 None None 12
2BAKA 2.2 Inactive DFGout BBAminus in-in none-out AQZ Type2 5 - 353 None None 12
4A9YA 2.2 Inactive DFGout BBAminus in-in none-out AQZ Type2 5 - 353 None None 12
4AA0A 1.8 Inactive DFGout BBAminus in-in none-out AA0 Type2 5 - 352 None None 12
3E93A 2.0 Inactive DFGout BBAminus in-in none-out 19B Type2 4 - 353 None None 3
3KQ7A 1.8 Inactive DFGout BBAminus in-in out-out KQ7 Type2 5 - 352 None None 0
3GI3A 2.4 Inactive DFGout BBAminus in-in none-out B10 Type2 5 - 352 None None 12
3IW8A 2.0 Inactive DFGout BBAminus in-in none-out HIZ Type3 4 - 352 C119S,C162S,A172C,F327L None 13
3LFBA 2.6 Inactive DFGout BBAminus in-in none-out Z87 Type3 4 - 353 C119S,C162S,A172C,F327L None 13
3LFCA 2.8 Inactive DFGout BBAminus in-in none-out Z86 Type3 4 - 354 C119S,C162S,A172C,F327L None 13
3NNVA 2.1 Inactive DFGout BBAminus in-in out-out 437 Type3 5 - 352 None None 0
3NNXA 2.28 Inactive DFGout BBAminus in-in out-out EDD Type3 5 - 352 None X182 7
1W82A 2.2 Inactive DFGout BBAminus in-in out-out L10 Type3 4 - 355 None None 0
1WBVA 2.0 Inactive DFGout BBAminus in-in out-out LI3 Type3 4 - 355 None None 0
3HV7A 2.4 Inactive DFGout BBAminus in-in none-out 1AU Type3 5 - 352 None None 11
2BAJA 2.25 Inactive DFGout BBAminus in-in out-out 1PP Type3 2 - 353 None None 0
3O8UA 2.1 Inactive DFGout BBAminus in-in none-out BMU Type3 5 - 352 F169Y None 13
3OBJA 2.4 Inactive DFGout BBAminus in-out none-out BMU Type3 5 - 352 F169R None 12
3K3IA 1.7 Inactive DFGout BBAminus in-in none-out JZJ I46 I46 Type3 Allosteric Allosteric 5 - 352 None None 12
5N64A 2.4 Inactive DFGout None in-in none-out 8OH Allosteric 5 - 354 None None 13
5N66A 2.4 Inactive DFGout None in-in none-out BW1 B96 Allosteric Type2 6 - 353 None None 13
4EH8A 2.2 Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1 4 - 354 None None 13
2FSMX 1.86 Inactive DFGout None in-in none-out No_ligand No_ligand 4 - 352 D176A,F327S None 14
2NPQA 1.8 Inactive DFGout None in-in none-out No_ligand No_ligand 4 - 351 None None 14
4GEOA 1.66 Inactive DFGout None in-in none-none No_ligand No_ligand 5 - 351 M194A,L195A,H228A,I229A,Y258A None 12
3MH3A 2.2 Inactive DFGout None in-in none-out No_ligand No_ligand 5 - 352 F169R None 12
3MH1A 2.2 Inactive DFGout None in-out none-out No_ligand No_ligand 5 - 352 F169G None 11
3IW5A 2.5 Inactive DFGout None in-out none-out DF3 Type1 4 - 353 C119S,C162S,A172C,F327L None 12
3L8SA 2.35 Inactive DFGout None in-in none-out BFF Type1 4 - 353 C119S,C162S,A172C,F327L None 13
6SFKA 1.8 Inactive DFGout None in-in none-out LB8 Type2 4 - 353 None None 11
3HECA 2.5 Inactive DFGout None in-in none-out STI Type2 5 - 352 None None 14
3NNUA 2.4 Inactive DFGout None in-in out-out EDB Type2 5 - 352 None None 0
3NNWA 1.89 Inactive DFGout None in-in out-out EDD Type2 4 - 352 None None 0
1KV2A 2.8 Inactive DFGout None in-in none-none B96 Type2 5 - 352 None None 15
1WBSA 1.8 Inactive DFGout None in-in out-out LI2 Type2 4 - 355 None None 0
1WBTA 2.0 Inactive DFGout None in-in out-out WBT Type2 4 - 355 None None 0
3UVRA 2.1 Inactive DFGout None in-in none-out 06F Type2 5 - 351 None None 12
4L8MA 2.1 Inactive DFGout None in-in out-out F46 Type2 5 - 352 None None 7
3BV3A 2.59 Inactive DFGout None in-in none-out P39 Type2 5 - 352 None None 10
2YISA 2.0 Inactive DFGout None in-in none-out YIS I46 Type2 Allosteric 5 - 353 None None 12
2YIWA 2.0 Inactive DFGout None in-in none-out YIW I46 Type2 Allosteric 5 - 353 None None 12
3K3JA 1.995 Inactive DFGout None in-in none-out F4C I46 Type2 Allosteric 5 - 352 None None 13
3LFDA 3.4 Inactive DFGout None in-in none-out Z85 Type3 4 - 353 C119S,C162S,A172C,F327L None 14
1KV1A 2.5 Inactive DFGout None in-in none-out BMU Type3 5 - 352 None None 13
3O8TA 2.0 Inactive DFGout None in-out none-out BMU Type3 5 - 352 F169A None 13
3OC1A 2.59 Inactive DFGout None in-in none-out BMU Type3 5 - 352 F169G None 14
4E8AA 2.7 Inactive None None in-in none-none 0OA Allosteric 4 - 351 None None 16
5N63A 2.4 Inactive None None in-in none-out 8OW Allosteric 5 - 353 None None 15
5O8UA 2.0 Inactive None None in-in none-out 9O5 Allosteric 5 - 352 S252C None 13
5O8VA 2.0 Inactive None None in-in none-out 9O2 Allosteric 5 - 354 S251C None 14
5N65A 2.0 Inactive None None in-in none-out 8OT 8OT Allosteric Type1 5 - 352 None None 15
4DLJA 2.6 Inactive None None in-in none-out 6RG 6RG Allosteric Type1 4 - 354 None None 14
4EH5A 2.0 Inactive None None in-in none-out IRG 0OM Allosteric Type1 4 - 354 None None 15
4EH6A 2.1 Inactive None None in-in none-out IRG 0ON Allosteric Type1 4 - 354 None None 14
4EH7A 2.1 Inactive None None in-in none-out IRG 0OO Allosteric Type1 4 - 354 None None 12
6QYXA 1.66 Inactive None None in-in out-out No_ligand No_ligand 4 - 352 None None 10
2FSTX 1.45 Inactive None None in-in none-out No_ligand No_ligand 5 - 352 D176A,F327L None 15
2FSLX 1.7 Inactive None None in-in none-out No_ligand No_ligand 4 - 354 D176A,F327S None 14
2FSOX 1.83 Inactive None None in-in none-out No_ligand No_ligand 5 - 353 D176A None 15
6M95A 1.8 Inactive None None in-in none-out J8S Type1 5 - 352 None None 15
3LFAA 2.1 Inactive None None in-in none-out 1N1 Type1 4 - 353 None None 15
3ZSHA 2.05 Inactive None None in-in none-out 469 Type1 4 - 352 None None 15
8A8MA 4.0 Inactive None None in-out out-out AP2 Type1 5 - 353 T180V None 0
4EH3A 2.4 Inactive None None in-out none-out NAR IRG Type1 Allosteric 4 - 354 None None 10
5OMHA 2.5 Inactive None None in-out none-out 9Y5 Type1.5_Back 5 - 353 None None 15

MAPK14 (Mitogen-activated protein kinase 14)

Group: CMGC
Total number of chains: 397
Spatial Dihedral Chains Representative
DFGin BLAminus 15 AF-Q16539-K1A
DFGin BLAplus 3 3HUBA
DFGin ABAminus 1 7PVUA
DFGin BLBminus 104 5R97A
DFGin BLBplus 100 3GC7A
DFGin None 51 1WBOA
DFGinter None 12 5WJJA
DFGout BBAminus 64 5LARA
DFGout None 28 1WBSA
None None 19 8A8MA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens MK14_HUMAN AF-Q16539-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 16 - 316 None None 0
Homo sapiens MK14_HUMAN 3HVCA 2.1 None DFGin BLAminus in-in none-none No_ligand No_ligand 5 - 352 None None 14
Homo sapiens MK14_HUMAN 1WBWA 2.41 Inactive DFGin BLAminus in-in out-out LI4 Type1 4 - 355 None None 0
Homo sapiens MK14_HUMAN 6ZQSA 1.95 Inactive DFGin BLAminus out-out in-in 3FF Type1 4 - 353 None X180,X182 0
Homo sapiens MK14_HUMAN 6TCAB 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 6 - 354 None X180,X182 0
Homo sapiens MK14_HUMAN 6TCAD 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 4 - 353 None X180,X182 0
Homo sapiens MK14_HUMAN 6TCAF 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 6 - 353 None X180,X182 0
Homo sapiens MK14_HUMAN 6TCAH 3.7 Inactive DFGin BLAminus out-out in-in 39G Type1.5_Back 4 - 353 None X180,X182 0
Homo sapiens MK14_HUMAN 3HUBA 2.25 Inactive DFGin BLAplus in-in none-none 469 Type1 4 - 352 C119S,C162S,A172C,F327L None 14
Homo sapiens MK14_HUMAN 3UVPA 2.4 Inactive DFGin BLAplus in-in none-out 048 Type1 5 - 352 None None 11
Homo sapiens MK14_HUMAN 3UVQA 2.2 Inactive DFGin BLAplus in-in none-none FS8 Type1 5 - 353 None None 13
Homo sapiens MK14_HUMAN 5N68A 1.85 Inactive DFGin BLBminus in-in none-none 8OK Allosteric 4 - 351 None None 14
Homo sapiens MK14_HUMAN 2Y8OA 1.95 Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 4 - 353 C162S None 11
Homo sapiens MK14_HUMAN 1R3CA 2.0 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 C162S None 0
Homo sapiens MK14_HUMAN 2LGCA 999.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand 2 - 354 None None 0
Homo sapiens MK14_HUMAN 5ETAA 2.8 Inactive DFGin BLBminus out-out none-none No_ligand No_ligand 4 - 354 None None 15
Homo sapiens MK14_HUMAN 5ETAB 2.8 Inactive DFGin BLBminus out-out none-none No_ligand No_ligand 4 - 353 None None 15
Homo sapiens MK14_HUMAN 1R39A 2.3 Inactive DFGin BLBminus in-out none-out No_ligand No_ligand 4 - 351 None None 3
Homo sapiens MK14_HUMAN 2OKRA 2.0 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 None None 10
Homo sapiens MK14_HUMAN 2OKRD 2.0 Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 5 - 355 None None 12
Homo sapiens MK14_HUMAN 2ONLA 4.0 Inactive DFGin BLBminus in-in out-none No_ligand No_ligand 4 - 352 None None 11
Homo sapiens MK14_HUMAN 2ONLB 4.0 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 352 None None 10
Homo sapiens MK14_HUMAN 5ETFA 2.4 Inactive DFGin BLBminus out-none none-out No_ligand No_ligand 4 - 353 None None 12
Homo sapiens MK14_HUMAN 1BMKA 2.4 Inactive DFGin BLBminus in-out out-out SB5 Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 3MW1A 2.8 Inactive DFGin BLBminus in-in none-out MIH Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 1DI9A 2.6 Inactive DFGin BLBminus in-in out-out MSQ Type1 4 - 351 None None 0
Homo sapiens MK14_HUMAN 1W7HA 2.214 Inactive DFGin BLBminus in-in out-out 3IP Type1 4 - 355 None None 0
Homo sapiens MK14_HUMAN 1W84A 2.2 Inactive DFGin BLBminus in-in out-out L12 Type1 4 - 355 None None 0
Homo sapiens MK14_HUMAN 2ZB0A 2.1 Inactive DFGin BLBminus in-in out-out GK3 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 1M7QA 2.4 Inactive DFGin BLBminus in-in out-out DQO Type1 4 - 351 None None 0
Homo sapiens MK14_HUMAN 1OUKA 2.5 Inactive DFGin BLBminus in-in out-out 084 Type1 4 - 351 None None 0
Homo sapiens MK14_HUMAN 1OUYA 2.5 Inactive DFGin BLBminus in-in out-out 094 Type1 4 - 353 None None 0
Homo sapiens MK14_HUMAN 1YQJA 2.0 Inactive DFGin BLBminus in-out out-out 6NP Type1 2 - 352 None None 0
Homo sapiens MK14_HUMAN 3ZYAA 1.9 Inactive DFGin BLBminus out-in none-out 2A8 Type1 1 - 353 None None 12
Homo sapiens MK14_HUMAN 1OZ1A 2.1 Inactive DFGin BLBminus in-in out-out FPH Type1 5 - 352 None None 0
Homo sapiens MK14_HUMAN 3FLQA 1.9 Inactive DFGin BLBminus in-in out-out 891 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 3FMJA 2.0 Inactive DFGin BLBminus in-in out-out FMJ Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3FSFA 2.1 Inactive DFGin BLBminus in-in none-out FSS Type1 5 - 352 None None 3
Homo sapiens MK14_HUMAN 1A9UA 2.5 Inactive DFGin BLBminus in-in out-out SB2 Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 1BL6A 2.5 Inactive DFGin BLBminus in-in out-out SB6 Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 1BL7A 2.5 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 3MPAA 2.1 Inactive DFGin BLBminus in-in none-none SB2 Type1 5 - 352 D168G None 14
Homo sapiens MK14_HUMAN 2ZB1A 2.5 Inactive DFGin BLBminus in-in none-out GK4 Type1.5_Back 4 - 352 None None 2
Homo sapiens MK14_HUMAN 5XYXA 2.61 Inactive DFGin BLBminus in-in none-out FTZ Type1.5_Back 4 - 353 None None 3
Homo sapiens MK14_HUMAN 5XYYA 1.7 Inactive DFGin BLBminus in-in out-out P0F Type1.5_Back 4 - 353 None None 0
Homo sapiens MK14_HUMAN 3NEWA 2.51 Inactive DFGin BLBplus in-in none-none 3NE Allosteric 5 - 352 C162S None 12
Homo sapiens MK14_HUMAN 4EH2A 2.0 Inactive DFGin BLBplus in-in none-out IRG 0OK Allosteric Type1 4 - 354 None None 12
Homo sapiens MK14_HUMAN 3MH2A 2.3 Inactive DFGin BLBplus in-out none-none No_ligand No_ligand 5 - 352 F169Y None 14
Homo sapiens MK14_HUMAN 5ETIA 2.8 Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 1 - 352 None None 0
Homo sapiens MK14_HUMAN 3FI4A 2.2 Inactive DFGin BLBplus in-in none-out FI4 Type1 4 - 352 R57K None 3
Homo sapiens MK14_HUMAN 3FKOA 2.0 Inactive DFGin BLBplus in-in none-out FKO Type1 5 - 352 R57K None 3
Homo sapiens MK14_HUMAN 3FLNC 1.9 Inactive DFGin BLBplus in-in none-out 3FN Type1 3 - 352 R57K None 3
Homo sapiens MK14_HUMAN 6OHDA 2.5 Inactive DFGin BLBplus in-in out-out MKP Type1 4 - 352 None None 10
Homo sapiens MK14_HUMAN 1OVEA 2.1 Inactive DFGin BLBplus in-in out-out 358 Type1 4 - 352 C162S None 0
Homo sapiens MK14_HUMAN 3GC7A 1.8 Inactive DFGin BLBplus in-in out-out B45 Type1 4 - 352 C162S None 0
Homo sapiens MK14_HUMAN 3S3IA 1.8 Inactive DFGin BLBplus in-in out-out CQ0 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 1ZZLA 2.0 Inactive DFGin BLBplus in-in out-out TZY Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 2YIXA 2.3 Inactive DFGin BLBplus in-in out-out YIX Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 3HRBA 2.2 Inactive DFGin BLBplus in-in out-out I39 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 1ZYJA 2.0 Inactive DFGin BLBplus in-in none-none BI5 Type1 5 - 352 None None 13
Homo sapiens MK14_HUMAN 1ZZ2A 2.0 Inactive DFGin BLBplus in-in none-out B11 Type1 5 - 352 None None 11
Homo sapiens MK14_HUMAN 2ZAZA 1.8 Inactive DFGin BLBplus in-in out-out GK1 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 3D7ZA 2.1 Inactive DFGin BLBplus in-in out-out GK5 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 3IPHA 2.1 Inactive DFGin BLBplus in-in none-out G11 Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3KF7A 2.0 Inactive DFGin BLBplus in-in none-out L9G Type1 5 - 352 None None 11
Homo sapiens MK14_HUMAN 3RINA 2.2 Inactive DFGin BLBplus in-in out-out I2O Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 5MTXA 1.8 Inactive DFGin BLBplus in-in none-none FJI Type1 5 - 352 None None 13
Homo sapiens MK14_HUMAN 5MTYA 2.31 Inactive DFGin BLBplus in-in none-none HB9 Type1 5 - 352 None None 14
Homo sapiens MK14_HUMAN 5TBEA 2.44 Inactive DFGin BLBplus in-in none-none 78L Type1 5 - 353 None None 13
Homo sapiens MK14_HUMAN 5TCOA 2.1 Inactive DFGin BLBplus in-in none-none 79Q Type1 6 - 352 None None 13
Homo sapiens MK14_HUMAN 6M9LA 2.45 Inactive DFGin BLBplus in-in none-none J9G Type1 5 - 352 None None 14
Homo sapiens MK14_HUMAN 3DS6A 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 6
Homo sapiens MK14_HUMAN 3DS6B 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 6
Homo sapiens MK14_HUMAN 3DS6C 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 3DS6D 2.9 Inactive DFGin BLBplus in-in out-out A17 Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 3GFEA 2.1 Inactive DFGin BLBplus in-in out-out P37 Type1 1 - 352 None None 0
Homo sapiens MK14_HUMAN 3ITZA 2.25 Inactive DFGin BLBplus in-in out-out P66 Type1 1 - 353 None None 0
Homo sapiens MK14_HUMAN 3LHJA 3.31 Inactive DFGin BLBplus in-in none-out LHJ Type1 5 - 352 None None 7
Homo sapiens MK14_HUMAN 3U8WA 2.15 Inactive DFGin BLBplus in-in out-out 09J Type1 4 - 352 None None 0
Homo sapiens MK14_HUMAN 2BALA 2.1 Inactive DFGin BLBplus in-in none-out PQA Type1 5 - 353 None None 11
Homo sapiens MK14_HUMAN 4AA4A 2.3 Inactive DFGin BLBplus in-in out-out QC0 Type1 5 - 355 None None 0
Homo sapiens MK14_HUMAN 4AA5A 2.38 Inactive DFGin BLBplus in-in out-out NQB Type1 5 - 352 None None 3
Homo sapiens MK14_HUMAN 4AACA 2.5 Inactive DFGin BLBplus in-in out-out AAV Type1 5 - 359 None None 0
Homo sapiens MK14_HUMAN 2QD9A 1.7 Inactive DFGin BLBplus in-in none-none LGF Type1 5 - 352 None None 13
Homo sapiens MK14_HUMAN 3MVLA 2.8 Inactive DFGin BLBplus in-in out-none 38P Type1 5 - 353 None None 10
Homo sapiens MK14_HUMAN 3MVLB 2.8 Inactive DFGin BLBplus in-in out-none 38P Type1 5 - 353 None None 10
Homo sapiens MK14_HUMAN 3MVMA 2.0 Inactive DFGin BLBplus in-in out-none 39P Type1 4 - 352 None None 9
Homo sapiens MK14_HUMAN 3MVMB 2.0 Inactive DFGin BLBplus in-in out-none 39P Type1 5 - 351 None None 11
Homo sapiens MK14_HUMAN 3NWWA 2.09 Inactive DFGin BLBplus in-in out-none 3NW Type1 5 - 353 None None 10
Homo sapiens MK14_HUMAN 3S4QA 2.27 Inactive DFGin BLBplus in-in none-out NK0 Type1 4 - 352 None None 11
Homo sapiens MK14_HUMAN 4KINA 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 5 - 352 None None 8
Homo sapiens MK14_HUMAN 4KINB 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 4 - 352 None None 8
Homo sapiens MK14_HUMAN 4KINC 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 4 - 352 None None 9
Homo sapiens MK14_HUMAN 4KIND 1.97 Inactive DFGin BLBplus in-in out-out 1M8 Type1 4 - 354 None None 9
Homo sapiens MK14_HUMAN 4KIPA 2.27 Inactive DFGin BLBplus in-in none-out 1R9 Type1 5 - 352 None None 11
Homo sapiens MK14_HUMAN 4KIPB 2.27 Inactive DFGin BLBplus in-in none-out 1R9 Type1 5 - 352 None None 10
Homo sapiens MK14_HUMAN 4KIQA 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
Homo sapiens MK14_HUMAN 4KIQB 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
Homo sapiens MK14_HUMAN 4KIQC 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
Homo sapiens MK14_HUMAN 4KIQD 2.5 Inactive DFGin BLBplus in-in none-out 1RA Type1 4 - 352 None None 11
Homo sapiens MK14_HUMAN 3FKLA 2.0 Inactive DFGin BLBplus in-in none-out FKL Type1 4 - 352 None None 5
Homo sapiens MK14_HUMAN 3FKNA 2.0 Inactive DFGin BLBplus in-in none-out FKN Type1 4 - 352 None None 3
Homo sapiens MK14_HUMAN 3FL4A 1.8 Inactive DFGin BLBplus in-in none-out FL4 Type1 4 - 352 None None 4
Homo sapiens MK14_HUMAN 3FLSA 2.3 Inactive DFGin BLBplus in-in none-out FLS Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3FLWA 2.1 Inactive DFGin BLBplus in-in none-out FLW Type1 4 - 352 None None 3
Homo sapiens MK14_HUMAN 3FLYA 1.8 Inactive DFGin BLBplus in-in none-out FLY Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3FLZA 2.23 Inactive DFGin BLBplus in-in none-out FLZ Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3FMHA 1.9 Inactive DFGin BLBplus in-in none-out 533 Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3FMKA 1.7 Inactive DFGin BLBplus in-in none-out FMK Type1 4 - 352 None None 3
Homo sapiens MK14_HUMAN 3FMMA 2.0 Inactive DFGin BLBplus in-in none-out XI2 Type1 4 - 352 None None 3
Homo sapiens MK14_HUMAN 3FMNA 1.9 Inactive DFGin BLBplus in-in none-out 530 Type1 4 - 352 None None 4
Homo sapiens MK14_HUMAN 3E92A 2.0 Inactive DFGin BLBplus in-in none-out G6A Type1 3 - 352 None None 1
Homo sapiens MK14_HUMAN 3MPTA 1.89 Inactive DFGin BLBplus in-in none-out 1GK Type1 4 - 352 None None 2
Homo sapiens MK14_HUMAN 3DT1A 2.8 Inactive DFGin BLBplus in-in out-out P40 Type1 1 - 352 None None 0
Homo sapiens MK14_HUMAN 4F9YA 1.85 Inactive DFGin BLBplus in-in none-out LM3 Type1 5 - 353 None None 10
Homo sapiens MK14_HUMAN 3HL7A 1.88 Inactive DFGin BLBplus in-in none-out I47 I46 Type1 Allosteric 6 - 352 None None 11
Homo sapiens MK14_HUMAN 3ROCA 1.7 Inactive DFGin BLBplus in-out none-out 29A 29B Type1 Allosteric 5 - 352 None None 11
Homo sapiens MK14_HUMAN 3HLLA 1.95 Inactive DFGin BLBplus in-out none-out I45 I46 PO2 Type1 Allosteric Allosteric 5 - 352 None None 11
Homo sapiens MK14_HUMAN 2I0HA 2.0 Inactive DFGin BLBplus in-in out-out 222 222 Type1 Type1 4 - 352 C162S None 0
Homo sapiens MK14_HUMAN 2RG5A 2.4 Inactive DFGin BLBplus in-in out-none 279 Type1.5_Back 4 - 351 None None 11
Homo sapiens MK14_HUMAN 3BX5A 2.4 Inactive DFGin BLBplus in-in out-none 304 Type1.5_Back 5 - 352 None None 10
Homo sapiens MK14_HUMAN 3L8XA 2.4 Inactive DFGin BLBplus in-in out-out N4D Type1.5_Back 4 - 352 None None 10
Homo sapiens MK14_HUMAN 2RG6A 1.72 Inactive DFGin BLBplus in-in out-out 287 287 Type1.5_Back Allosteric 4 - 352 None None 10
Homo sapiens MK14_HUMAN 4E6AA 2.09 Inactive DFGin None in-in none-none 0O9 Allosteric 4 - 351 None None 16
Homo sapiens MK14_HUMAN 4E6CA 2.39 Inactive DFGin None in-in none-none 0O8 Allosteric 4 - 351 None None 15
Homo sapiens MK14_HUMAN 5N67A 1.9 Inactive DFGin None in-in none-out 8ON Allosteric 5 - 353 None None 14
Homo sapiens MK14_HUMAN 4DLIA 1.91 Inactive DFGin None in-in none-out IRG IRG Allosteric Allosteric 5 - 354 None None 12
Homo sapiens MK14_HUMAN 4EH4A 2.5 Inactive DFGin None in-in none-out IRG 0OL Allosteric Type1 4 - 354 None None 10
Homo sapiens MK14_HUMAN 3C5UA 2.8 Inactive DFGin None in-in none-out P41 P41 Allosteric Type1 4 - 352 None None 11
Homo sapiens MK14_HUMAN 4E5AX 1.87 Inactive DFGin None in-in none-out No_ligand No_ligand 3 - 353 W197A None 14
Homo sapiens MK14_HUMAN 3OD6X 2.682 Inactive DFGin None in-in in-out No_ligand No_ligand 4 - 352 Y323T None 0
Homo sapiens MK14_HUMAN 3OEFX 1.6 Inactive DFGin None in-in out-none No_ligand No_ligand 5 - 352 Y323F None 11
Homo sapiens MK14_HUMAN 3ODYX 2.2 Inactive DFGin None out-out none-out No_ligand No_ligand 4 - 353 Y323Q None 10
Homo sapiens MK14_HUMAN 3MGYA 2.1 Inactive DFGin None in-in none-none No_ligand No_ligand 5 - 352 None None 15
Homo sapiens MK14_HUMAN 4E5BA 2.0 Inactive DFGin None in-in none-none No_ligand No_ligand 4 - 351 None None 16
Homo sapiens MK14_HUMAN 3ODZX 2.3 Inactive DFGin None out-out none-out No_ligand No_ligand 4 - 353 Y323R None 10
Homo sapiens MK14_HUMAN 5ETCA 2.422 Inactive DFGin None in-out out-out No_ligand No_ligand 1 - 352 None None 0
Homo sapiens MK14_HUMAN 1WFCA 2.3 Inactive DFGin None in-out none-out No_ligand No_ligand 5 - 351 None None 5
Homo sapiens MK14_HUMAN 3MH0A 2.0 Inactive DFGin None in-in none-none No_ligand No_ligand 5 - 352 F169A None 12
Homo sapiens MK14_HUMAN 3IW6A 2.1 Inactive DFGin None in-in none-out PP0 Type1 4 - 353 C119S,C162S,A172C,F327L None 11
Homo sapiens MK14_HUMAN 3IW7A 2.4 Inactive DFGin None in-in none-out IPK Type1 4 - 352 C119S,C162S,A172C,F327L None 12
Homo sapiens MK14_HUMAN 2BAQA 2.8 Inactive DFGin None in-in none-out PQB Type1 5 - 351 V30I None 9
Homo sapiens MK14_HUMAN 1WBOA 2.16 Inactive DFGin None in-in out-out 2CH Type1 4 - 354 None None 0
Homo sapiens MK14_HUMAN 5OMGA 2.0 Inactive DFGin None in-in none-out 9Y8 Type1 4 - 353 None None 10
Homo sapiens MK14_HUMAN 3QUDA 2.0 Inactive DFGin None in-in out-out N3F Type1 4 - 354 None None 6
Homo sapiens MK14_HUMAN 3QUEA 2.7 Inactive DFGin None in-in out-out 3FF Type1 5 - 353 None None 6
Homo sapiens MK14_HUMAN 3ZSIA 2.4 Inactive DFGin None in-in none-none 52P Type1 6 - 352 None None 13
Homo sapiens MK14_HUMAN 3FC1X 2.4 Inactive DFGin None in-in none-out 52P Type1 5 - 353 None None 8
Homo sapiens MK14_HUMAN 3BV2A 2.4 Inactive DFGin None in-in out-out P38 Type1 5 - 351 None None 10
Homo sapiens MK14_HUMAN 3OCGA 2.21 Inactive DFGin None in-in none-none OCG Type1 4 - 352 None None 13
Homo sapiens MK14_HUMAN 2GFSA 1.752 Inactive DFGin None in-in none-out PQB Type1 5 - 352 None None 4
Homo sapiens MK14_HUMAN 3FMLA 2.1 Inactive DFGin None in-in out-out FML Type1 4 - 352 None None 1
Homo sapiens MK14_HUMAN 3FSKA 2.0 Inactive DFGin None in-in none-out RO6 Type1 5 - 352 None None 6
Homo sapiens MK14_HUMAN 3HA8A 2.48 Inactive DFGin None in-out none-out 5JZ Type1 4 - 352 None None 7
Homo sapiens MK14_HUMAN 4F9WA 2.0 Inactive DFGin None in-out none-out LM4 Type1 5 - 352 None None 12
Homo sapiens MK14_HUMAN 4FA2A 2.0 Inactive DFGin None in-in none-out SB0 Type1 4 - 353 None None 11
Homo sapiens MK14_HUMAN 4ZTHA 2.15 Inactive DFGin None in-in none-out VVT Type1 4 - 353 None None 11
Homo sapiens MK14_HUMAN 3O8PA 2.1 Inactive DFGin None in-out none-out BMU Type1 5 - 351 D168G None 11
Homo sapiens MK14_HUMAN 3OBGA 2.8 Inactive DFGin None in-in none-none SB2 Type1 5 - 352 F169G None 12
Homo sapiens MK14_HUMAN 4EWQA 2.1 Inactive DFGin None in-in out-out MWL MWL Type1 Allosteric 5 - 353 None X180 2
Homo sapiens MK14_HUMAN 4R3CA 2.06 Inactive DFGin None in-out none-out 3GF 3GF Type1 Allosteric 4 - 352 None None 13
Homo sapiens MK14_HUMAN 3HP2A 2.15 Inactive DFGin None in-in none-out P36 I46 I46 Type1 Allosteric Allosteric 4 - 355 None None 11
Homo sapiens MK14_HUMAN 3HP5A 2.3 Inactive DFGin None in-in none-out 52P I46 I46 Type1 Allosteric Allosteric 6 - 352 None None 12
Homo sapiens MK14_HUMAN 4EH9A 2.1 Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3 5 - 354 None None 11
Homo sapiens MK14_HUMAN 3GCPA 2.25 Inactive DFGinter None in-in none-none SB2 Type1 4 - 352 C119S,C162S,A172C,F327L None 12
Homo sapiens MK14_HUMAN 5WJJA 1.6 Inactive DFGinter None in-in out-out AQY Type1 5 - 352 None None 6
Homo sapiens MK14_HUMAN 6ANLA 2.0 Inactive DFGinter None in-in none-out T75 Type1 4 - 352 C119S,C162S None 11
Homo sapiens MK14_HUMAN 5ML5A 1.9 Inactive DFGinter None in-in none-none 1VI Type1 5 - 352 None None 14
Homo sapiens MK14_HUMAN 3HUCA 1.8 Inactive DFGinter None in-in none-out G97 Type1 4 - 352 None None 12
Homo sapiens MK14_HUMAN 3ZS5A 1.6 Inactive DFGinter None in-in none-out SB2 Type1 2 - 352 None None 12
Homo sapiens MK14_HUMAN 3ZSGA 1.89 Inactive DFGinter None in-in none-out T75 Type1 4 - 352 None None 12
Homo sapiens MK14_HUMAN 6HWTA 1.7 Inactive DFGinter None in-in out-none GXH Type1 5 - 352 None None 11
Homo sapiens MK14_HUMAN 6HWUA 2.3 Inactive DFGinter None in-in none-out GE5 Type1 5 - 353 None None 11
Homo sapiens MK14_HUMAN 6HWVA 1.7 Inactive DFGinter None in-in none-none GEW Type1 5 - 352 None None 12
Homo sapiens MK14_HUMAN 4EHVA 1.6 Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric 5 - 352 None None 11
Homo sapiens MK14_HUMAN 6QDZA 1.73 Inactive DFGout BBAminus in-in none-out I46 HYK Allosteric Type2 5 - 352 None None 13
Homo sapiens MK14_HUMAN 6QE1A 1.85 Inactive DFGout BBAminus in-in none-out I46 HYW Allosteric Type2 5 - 352 None None 13
Homo sapiens MK14_HUMAN 3GCQA 2.0 Inactive DFGout BBAminus in-out none-out 1BU Type2 4 - 355 C119S,C162S,A172C,F327L None 12
Homo sapiens MK14_HUMAN 3GCSA 2.1 Inactive DFGout BBAminus in-out none-none BAX Type2 5 - 352 C119S,C162S,A172C,F327L None 14
Homo sapiens MK14_HUMAN 3GCVA 2.3 Inactive DFGout BBAminus in-in none-out SS6 Type2 4 - 353 C119S,C162S,A172C,F327L None 10
Homo sapiens MK14_HUMAN 3HV3A 2.0 Inactive DFGout BBAminus in-in none-out R49 Type2 4 - 353 C119S,C162S,A172C,F327L None 12
Homo sapiens MK14_HUMAN 3LFEA 2.3 Inactive DFGout BBAminus in-in none-out Z84 Type2 4 - 353 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 3LFFA 1.5 Inactive DFGout BBAminus in-in none-out Z83 Type2 5 - 352 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 3PG3A 2.0 Inactive DFGout BBAminus out-out none-out DG7 Type2 4 - 353 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 6SFIA 1.6 Inactive DFGout BBAminus in-in out-out LB5 Type2 4 - 353 None None 10
Homo sapiens MK14_HUMAN 6SFJA 1.95 Inactive DFGout BBAminus in-in out-out LBB Type2 4 - 353 None None 9
Homo sapiens MK14_HUMAN 6SFOA 1.75 Inactive DFGout BBAminus in-in none-out LBE Type2 5 - 352 None None 12
Homo sapiens MK14_HUMAN 6ZWPA 1.9 Inactive DFGout BBAminus in-in none-out OE8 Type2 4 - 353 None None 12
Homo sapiens MK14_HUMAN 3CTQA 1.95 Inactive DFGout BBAminus in-in none-out 337 Type2 5 - 352 None None 12
Homo sapiens MK14_HUMAN 5MZ3A 2.15 Inactive DFGout BBAminus in-in out-out 8EN Type2 4 - 353 C162S None 0
Homo sapiens MK14_HUMAN 3HEGA 2.2 Inactive DFGout BBAminus in-in none-out BAX Type2 5 - 352 None None 11
Homo sapiens MK14_HUMAN 1W83A 2.5 Inactive DFGout BBAminus in-in out-out L11 Type2 4 - 355 None None 0
Homo sapiens MK14_HUMAN 1WBNA 2.4 Inactive DFGout BBAminus in-in out-out L09 Type2 4 - 355 None None 0
Homo sapiens MK14_HUMAN 3D83A 1.9 Inactive DFGout BBAminus in-in out-out GK6 Type2 4 - 352 None None 0
Homo sapiens MK14_HUMAN 3GCUA 2.1 Inactive DFGout BBAminus in-in none-out R48 Type2 4 - 352 None None 10
Homo sapiens MK14_HUMAN 3GCUB 2.1 Inactive DFGout BBAminus in-in none-out R48 Type2 5 - 352 None None 11
Homo sapiens MK14_HUMAN 3HV4A 2.6 Inactive DFGout BBAminus in-in none-out L51 Type2 4 - 352 None None 10
Homo sapiens MK14_HUMAN 3HV4B 2.6 Inactive DFGout BBAminus in-in none-out L51 Type2 5 - 352 None None 10
Homo sapiens MK14_HUMAN 3HV5A 2.25 Inactive DFGout BBAminus in-in none-out R24 Type2 4 - 352 None None 10
Homo sapiens MK14_HUMAN 3HV5B 2.25 Inactive DFGout BBAminus in-in none-out R24 Type2 4 - 352 None None 10
Homo sapiens MK14_HUMAN 3HV6A 1.95 Inactive DFGout BBAminus in-out none-out R39 Type2 4 - 352 None None 12
Homo sapiens MK14_HUMAN 2BAKA 2.2 Inactive DFGout BBAminus in-in none-out AQZ Type2 5 - 353 None None 12
Homo sapiens MK14_HUMAN 4A9YA 2.2 Inactive DFGout BBAminus in-in none-out AQZ Type2 5 - 353 None None 12
Homo sapiens MK14_HUMAN 4AA0A 1.8 Inactive DFGout BBAminus in-in none-out AA0 Type2 5 - 352 None None 12
Homo sapiens MK14_HUMAN 3E93A 2.0 Inactive DFGout BBAminus in-in none-out 19B Type2 4 - 353 None None 3
Homo sapiens MK14_HUMAN 3KQ7A 1.8 Inactive DFGout BBAminus in-in out-out KQ7 Type2 5 - 352 None None 0
Homo sapiens MK14_HUMAN 3GI3A 2.4 Inactive DFGout BBAminus in-in none-out B10 Type2 5 - 352 None None 12
Homo sapiens MK14_HUMAN 3IW8A 2.0 Inactive DFGout BBAminus in-in none-out HIZ Type3 4 - 352 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 3LFBA 2.6 Inactive DFGout BBAminus in-in none-out Z87 Type3 4 - 353 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 3LFCA 2.8 Inactive DFGout BBAminus in-in none-out Z86 Type3 4 - 354 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 3NNVA 2.1 Inactive DFGout BBAminus in-in out-out 437 Type3 5 - 352 None None 0
Homo sapiens MK14_HUMAN 3NNXA 2.28 Inactive DFGout BBAminus in-in out-out EDD Type3 5 - 352 None X182 7
Homo sapiens MK14_HUMAN 1W82A 2.2 Inactive DFGout BBAminus in-in out-out L10 Type3 4 - 355 None None 0
Homo sapiens MK14_HUMAN 1WBVA 2.0 Inactive DFGout BBAminus in-in out-out LI3 Type3 4 - 355 None None 0
Homo sapiens MK14_HUMAN 3HV7A 2.4 Inactive DFGout BBAminus in-in none-out 1AU Type3 5 - 352 None None 11
Homo sapiens MK14_HUMAN 2BAJA 2.25 Inactive DFGout BBAminus in-in out-out 1PP Type3 2 - 353 None None 0
Homo sapiens MK14_HUMAN 3O8UA 2.1 Inactive DFGout BBAminus in-in none-out BMU Type3 5 - 352 F169Y None 13
Homo sapiens MK14_HUMAN 3OBJA 2.4 Inactive DFGout BBAminus in-out none-out BMU Type3 5 - 352 F169R None 12
Homo sapiens MK14_HUMAN 3K3IA 1.7 Inactive DFGout BBAminus in-in none-out JZJ I46 I46 Type3 Allosteric Allosteric 5 - 352 None None 12
Homo sapiens MK14_HUMAN 5N64A 2.4 Inactive DFGout None in-in none-out 8OH Allosteric 5 - 354 None None 13
Homo sapiens MK14_HUMAN 5N66A 2.4 Inactive DFGout None in-in none-out BW1 B96 Allosteric Type2 6 - 353 None None 13
Homo sapiens MK14_HUMAN 4EH8A 2.2 Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1 4 - 354 None None 13
Homo sapiens MK14_HUMAN 2FSMX 1.86 Inactive DFGout None in-in none-out No_ligand No_ligand 4 - 352 D176A,F327S None 14
Homo sapiens MK14_HUMAN 2NPQA 1.8 Inactive DFGout None in-in none-out No_ligand No_ligand 4 - 351 None None 14
Homo sapiens MK14_HUMAN 4GEOA 1.66 Inactive DFGout None in-in none-none No_ligand No_ligand 5 - 351 M194A,L195A,H228A,I229A,Y258A None 12
Homo sapiens MK14_HUMAN 3MH3A 2.2 Inactive DFGout None in-in none-out No_ligand No_ligand 5 - 352 F169R None 12
Homo sapiens MK14_HUMAN 3MH1A 2.2 Inactive DFGout None in-out none-out No_ligand No_ligand 5 - 352 F169G None 11
Homo sapiens MK14_HUMAN 3IW5A 2.5 Inactive DFGout None in-out none-out DF3 Type1 4 - 353 C119S,C162S,A172C,F327L None 12
Homo sapiens MK14_HUMAN 3L8SA 2.35 Inactive DFGout None in-in none-out BFF Type1 4 - 353 C119S,C162S,A172C,F327L None 13
Homo sapiens MK14_HUMAN 6SFKA 1.8 Inactive DFGout None in-in none-out LB8 Type2 4 - 353 None None 11
Homo sapiens MK14_HUMAN 3HECA 2.5 Inactive DFGout None in-in none-out STI Type2 5 - 352 None None 14
Homo sapiens MK14_HUMAN 3NNUA 2.4 Inactive DFGout None in-in out-out EDB Type2 5 - 352 None None 0
Homo sapiens MK14_HUMAN 3NNWA 1.89 Inactive DFGout None in-in out-out EDD Type2 4 - 352 None None 0
Homo sapiens MK14_HUMAN 1KV2A 2.8 Inactive DFGout None in-in none-none B96 Type2 5 - 352 None None 15
Homo sapiens MK14_HUMAN 1WBSA 1.8 Inactive DFGout None in-in out-out LI2 Type2 4 - 355 None None 0
Homo sapiens MK14_HUMAN 1WBTA 2.0 Inactive DFGout None in-in out-out WBT Type2 4 - 355 None None 0
Homo sapiens MK14_HUMAN 3UVRA 2.1 Inactive DFGout None in-in none-out 06F Type2 5 - 351 None None 12
Homo sapiens MK14_HUMAN 4L8MA 2.1 Inactive DFGout None in-in out-out F46 Type2 5 - 352 None None 7
Homo sapiens MK14_HUMAN 3BV3A 2.59 Inactive DFGout None in-in none-out P39 Type2 5 - 352 None None 10
Homo sapiens MK14_HUMAN 2YISA 2.0 Inactive DFGout None in-in none-out YIS I46 Type2 Allosteric 5 - 353 None None 12
Homo sapiens MK14_HUMAN 2YIWA 2.0 Inactive DFGout None in-in none-out YIW I46 Type2 Allosteric 5 - 353 None None 12
Homo sapiens MK14_HUMAN 3K3JA 1.995 Inactive DFGout None in-in none-out F4C I46 Type2 Allosteric 5 - 352 None None 13
Homo sapiens MK14_HUMAN 3LFDA 3.4 Inactive DFGout None in-in none-out Z85 Type3 4 - 353 C119S,C162S,A172C,F327L None 14
Homo sapiens MK14_HUMAN 1KV1A 2.5 Inactive DFGout None in-in none-out BMU Type3 5 - 352 None None 13
Homo sapiens MK14_HUMAN 3O8TA 2.0 Inactive DFGout None in-out none-out BMU Type3 5 - 352 F169A None 13
Homo sapiens MK14_HUMAN 3OC1A 2.59 Inactive DFGout None in-in none-out BMU Type3 5 - 352 F169G None 14
Homo sapiens MK14_HUMAN 4E8AA 2.7 Inactive None None in-in none-none 0OA Allosteric 4 - 351 None None 16
Homo sapiens MK14_HUMAN 5N63A 2.4 Inactive None None in-in none-out 8OW Allosteric 5 - 353 None None 15
Homo sapiens MK14_HUMAN 5O8UA 2.0 Inactive None None in-in none-out 9O5 Allosteric 5 - 352 S252C None 13
Homo sapiens MK14_HUMAN 5O8VA 2.0 Inactive None None in-in none-out 9O2 Allosteric 5 - 354 S251C None 14
Homo sapiens MK14_HUMAN 5N65A 2.0 Inactive None None in-in none-out 8OT 8OT Allosteric Type1 5 - 352 None None 15
Homo sapiens MK14_HUMAN 4DLJA 2.6 Inactive None None in-in none-out 6RG 6RG Allosteric Type1 4 - 354 None None 14
Homo sapiens MK14_HUMAN 4EH5A 2.0 Inactive None None in-in none-out IRG 0OM Allosteric Type1 4 - 354 None None 15
Homo sapiens MK14_HUMAN 4EH6A 2.1 Inactive None None in-in none-out IRG 0ON Allosteric Type1 4 - 354 None None 14
Homo sapiens MK14_HUMAN 4EH7A 2.1 Inactive None None in-in none-out IRG 0OO Allosteric Type1 4 - 354 None None 12
Homo sapiens MK14_HUMAN 6QYXA 1.66 Inactive None None in-in out-out No_ligand No_ligand 4 - 352 None None 10
Homo sapiens MK14_HUMAN 2FSTX 1.45 Inactive None None in-in none-out No_ligand No_ligand 5 - 352 D176A,F327L None 15
Homo sapiens MK14_HUMAN 2FSLX 1.7 Inactive None None in-in none-out No_ligand No_ligand 4 - 354 D176A,F327S None 14
Homo sapiens MK14_HUMAN 2FSOX 1.83 Inactive None None in-in none-out No_ligand No_ligand 5 - 353 D176A None 15
Homo sapiens MK14_HUMAN 6M95A 1.8 Inactive None None in-in none-out J8S Type1 5 - 352 None None 15
Homo sapiens MK14_HUMAN 3LFAA 2.1 Inactive None None in-in none-out 1N1 Type1 4 - 353 None None 15
Homo sapiens MK14_HUMAN 3ZSHA 2.05 Inactive None None in-in none-out 469 Type1 4 - 352 None None 15
Homo sapiens MK14_HUMAN 8A8MA 4.0 Inactive None None in-out out-out AP2 Type1 5 - 353 T180V None 0
Homo sapiens MK14_HUMAN 4EH3A 2.4 Inactive None None in-out none-out NAR IRG Type1 Allosteric 4 - 354 None None 10
Homo sapiens MK14_HUMAN 5OMHA 2.5 Inactive None None in-out none-out 9Y5 Type1.5_Back 5 - 353 None None 15
Mus musculus MK14_MOUSE 7PVUA 2.154 Inactive DFGin ABAminus out-out none-out No_ligand No_ligand 5 - 353 None None 12
Mus musculus MK14_MOUSE 2OZAB 2.7 None DFGin BLAminus out-out none-out No_ligand No_ligand 6 - 353 None None 8
Mus musculus MK14_MOUSE 3PY3A 2.1 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 1 - 354 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZE 2.6 Active DFGin BLAminus in-in in-in AGS Type1 4 - 353 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZF 2.6 Active DFGin BLAminus in-in in-in AGS Type1 5 - 353 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZG 2.6 Inactive DFGin BLAminus in-out in-in AGS Type1 5 - 353 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZH 2.6 None DFGin BLAminus in-none in-in AGS Type1 5 - 352 None X180,X182 0
Mus musculus MK14_MOUSE 4TYHB 3.0 None DFGin BLAminus out-out none-out 39G Type1.5_Back 6 - 353 None None 8
Mus musculus MK14_MOUSE 5R8VA 1.479 Inactive DFGin BLBminus in-in none-out SLV Allosteric 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R8WA 1.5 Inactive DFGin BLBminus in-in out-out JND Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R8XA 1.73 Inactive DFGin BLBminus in-in out-out SLY Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R93A 1.489 Inactive DFGin BLBminus in-in none-out SOJ Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R94A 1.45 Inactive DFGin BLBminus in-in none-out SOV Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R95A 1.59 Inactive DFGin BLBminus in-in none-out SQ4 Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R96A 1.767 Inactive DFGin BLBminus in-in none-out SQ7 Allosteric 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R98A 1.68 Inactive DFGin BLBminus in-in out-out SQG Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9AA 1.53 Inactive DFGin BLBminus in-in out-out SQM Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9BA 1.657 Inactive DFGin BLBminus in-in none-out JGM Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 5R9GA 1.73 Inactive DFGin BLBminus in-in out-out RGY Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9HA 1.49 Inactive DFGin BLBminus in-in none-out SQV Allosteric 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R9OA 1.6 Inactive DFGin BLBminus in-in out-out 54F Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9SA 1.7 Inactive DFGin BLBminus in-in out-out A9B Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9TA 1.8 Inactive DFGin BLBminus in-in out-out 6T5 Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9VA 1.45 Inactive DFGin BLBminus in-in out-out SSY Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9XA 1.72 Inactive DFGin BLBminus in-in out-out NZ4 Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9ZA 1.66 Inactive DFGin BLBminus in-in out-out AYS Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA3A 1.57 Inactive DFGin BLBminus in-in out-out SVD Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA4A 1.59 Inactive DFGin BLBminus in-in out-out SVG Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA5A 1.54 Inactive DFGin BLBminus in-in out-out SVJ Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 6SOIA 1.55 Inactive DFGin BLBminus in-in none-out LOK Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 6SO1A 1.66 Inactive DFGin BLBminus in-in none-out LO5 Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 6SO2A 1.6 Inactive DFGin BLBminus in-in none-out JGG Allosteric 4 - 352 None None 2
Mus musculus MK14_MOUSE 6SO4A 1.51 Inactive DFGin BLBminus in-in none-out LO8 Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 6SODA 1.87 Inactive DFGin BLBminus in-none none-out LOE Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 6SOTA 1.54 Inactive DFGin BLBminus in-in none-out LOQ Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 5R9MA 1.809 Inactive DFGin BLBminus in-in none-out A7K A7K Allosteric Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 1LEWA 2.3 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 5 - 354 None None 9
Mus musculus MK14_MOUSE 1LEZA 2.3 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 353 None None 7
Mus musculus MK14_MOUSE 4KA3A 2.707 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand 4 - 354 None None 11
Mus musculus MK14_MOUSE 3P4KA 2.304 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand 4 - 353 S28A None 12
Mus musculus MK14_MOUSE 5UOJA 2.1 Inactive DFGin BLBminus out-out none-out No_ligand No_ligand 5 - 353 None None 6
Mus musculus MK14_MOUSE 7Z9TAAA 2.6 Inactive DFGin BLBminus in-out out-out 87B Type1 5 - 353 None None 0
Mus musculus MK14_MOUSE 5R90A 1.619 Inactive DFGin BLBminus in-in none-out SNJ Type1 4 - 352 None None 2
Mus musculus MK14_MOUSE 5R91A 1.731 Inactive DFGin BLBminus in-in out-out SNV Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R92A 1.66 Inactive DFGin BLBminus in-in none-out SO7 Type1 4 - 352 None None 2
Mus musculus MK14_MOUSE 5R99A 1.89 Inactive DFGin BLBminus in-in out-out SU7 Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9CA 1.74 Inactive DFGin BLBminus in-in out-out 7ZC Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9FA 1.986 Inactive DFGin BLBminus in-in none-out SQP Type1 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R9IA 1.813 Inactive DFGin BLBminus in-in none-out SQY Type1 5 - 352 None None 2
Mus musculus MK14_MOUSE 5R9JA 1.52 Inactive DFGin BLBminus in-in none-out LXS Type1 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R9LA 1.47 Inactive DFGin BLBminus in-in none-out SRJ Type1 4 - 352 None None 2
Mus musculus MK14_MOUSE 5R9NA 1.688 Inactive DFGin BLBminus out-out out-out JFS Type1 4 - 352 None None 0
Mus musculus MK14_MOUSE 5R9PA 1.72 Inactive DFGin BLBminus in-in out-out SFY Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9RA 1.76 Inactive DFGin BLBminus in-in out-out K3D Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9YA 1.57 Inactive DFGin BLBminus in-in none-out SU7 Type1 5 - 352 None None 2
Mus musculus MK14_MOUSE 5RA0A 1.91 Inactive DFGin BLBminus in-out out-out JFS Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA2A 1.57 Inactive DFGin BLBminus in-in out-out SV4 Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA6A 1.86 Inactive DFGin BLBminus in-in out-out SVM Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 4LOPB 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 353 None None 0
Mus musculus MK14_MOUSE 4LOPC 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 4LOQA 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 3 - 354 None None 0
Mus musculus MK14_MOUSE 4LOQB 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 4LOQC 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 353 None None 0
Mus musculus MK14_MOUSE 4LOQD 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 354 None None 0
Mus musculus MK14_MOUSE 5R8UA 1.48 Inactive DFGin BLBminus in-in out-out SLS Type1.5_Back 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA7A 1.92 Inactive DFGin BLBminus in-in out-out SW7 Type1.5_Back 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA8A 1.78 Inactive DFGin BLBminus in-in out-out 2O6 Type1.5_Back 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R8YA 1.679 Inactive DFGin BLBminus in-in out-out SMV Type3 4 - 352 None None 0
Mus musculus MK14_MOUSE 5R8ZA 1.65 Inactive DFGin BLBminus in-in out-out SN4 Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R97A 1.438 Inactive DFGin BLBminus in-in out-out RUY Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9DA 1.69 Inactive DFGin BLBminus in-in out-out N9J Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9EA 1.775 Inactive DFGin BLBminus in-in none-out S7S Type3 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R9KA 1.498 Inactive DFGin BLBminus in-in out-out SR4 Type3 4 - 352 None None 0
Mus musculus MK14_MOUSE 5R9QA 1.645 Inactive DFGin BLBminus in-in out-out LVD Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9WA 1.89 Inactive DFGin BLBminus in-in out-out STV Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA1A 1.61 Inactive DFGin BLBminus in-in out-out PO6 Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA9A 1.68 Inactive DFGin BLBminus in-in out-out SWD Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 7Z9TBBB 2.6 Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric 4 - 353 None None 0
Mus musculus MK14_MOUSE 6Y7ZA 1.35 Inactive DFGin BLBplus in-in none-out OG2 SB4 Allosteric Type1 5 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y80A 1.24 Inactive DFGin BLBplus in-in out-out OFZ SB4 Allosteric Type1 5 - 359 C162S None 8
Mus musculus MK14_MOUSE 6Y85A 1.58 Inactive DFGin BLBplus in-in none-out OG8 SB4 Allosteric Type1 5 - 359 C162S None 11
Mus musculus MK14_MOUSE 1YWRA 1.95 Inactive DFGin BLBplus in-in out-out LI9 Type1 5 - 352 T180A,Y182F None 9
Mus musculus MK14_MOUSE 2GHLA 2.099 Inactive DFGin BLBplus in-in out-out LIB Type1 5 - 352 T180A,Y182F None 10
Mus musculus MK14_MOUSE 7PVUB 2.154 Inactive DFGin BLBplus in-out none-none 8DI Type1 5 - 353 None None 13
Mus musculus MK14_MOUSE 6Y8HA 1.37 Inactive DFGin BLBplus in-in none-out SB4 Type1 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 8ACMAAA 2.14 Inactive DFGin BLBplus in-in none-none SB2 Type1 4 - 353 None None 13
Mus musculus MK14_MOUSE 4LOOA 1.95 Inactive DFGin BLBplus in-in out-out SB4 Type1 5 - 353 None None 0
Mus musculus MK14_MOUSE 4LOPA 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 4LOPD 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 5O90A 2.49 Inactive DFGin BLBplus in-in none-out SB4 Type1 5 - 353 T185G None 9
Mus musculus MK14_MOUSE 6Y7WA 1.39 Inactive DFGin BLBplus in-in none-out SB4 OFW Type1 Allosteric 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y7XA 1.45 Inactive DFGin BLBplus in-in none-out SB4 OFQ Type1 Allosteric 5 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y81A 1.54 Inactive DFGin BLBplus in-in none-out SB4 OG5 Type1 Allosteric 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y82A 1.44 Inactive DFGin BLBplus in-in out-out SB4 308 Type1 Allosteric 6 - 360 C162S None 7
Mus musculus MK14_MOUSE 6YCWA 1.34 Inactive DFGin BLBplus in-in none-out SB4 OL8 Type1 Allosteric 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 6SOVA 1.31 Inactive DFGin BLBplus in-in none-out SB4 LOT LOW Type1 Allosteric Allosteric 6 - 359 None None 9
Mus musculus MK14_MOUSE 6SP9A 1.22 Inactive DFGin BLBplus in-in out-out SB4 LOT LOT Type1 Allosteric Allosteric 5 - 359 None None 7
Mus musculus MK14_MOUSE 6Y7YA 1.51 Inactive DFGin BLBplus in-in none-out SB4 OFQ LOT LOT Type1 Allosteric Allosteric Allosteric 6 - 359 C162S None 11
Mus musculus MK14_MOUSE 6SPLA 1.38 Inactive DFGin BLBplus in-in out-out SB4 LOW LOW LOW Type1 Allosteric Type1 Allosteric 6 - 359 None None 9
Mus musculus MK14_MOUSE 7Z6IAAA 2.25 Inactive DFGin BLBplus in-in out-out IIM 87B Type1 Type1 5 - 354 C162S None 0
Mus musculus MK14_MOUSE 6SOUA 1.5 Inactive DFGin None in-in out-out LPZ LPZ Allosteric Type1 5 - 352 None None 3
Mus musculus MK14_MOUSE 3TG1A 2.71 Inactive DFGin None in-in none-out No_ligand No_ligand 5 - 352 None None 14
Mus musculus MK14_MOUSE 2GHMA 2.35 Inactive DFGin None in-in none-out LIC Type1 5 - 352 T180A,Y182F None 11
Mus musculus MK14_MOUSE 1YW2A 2.01 Inactive DFGin None in-in out-out PGJ Type1 4 - 353 T180A,Y182F None 9
Mus musculus MK14_MOUSE 2GTMA 1.9 Inactive DFGin None in-in out-out LID Type1 5 - 352 None None 4
Mus musculus MK14_MOUSE 2GTNA 1.8 Inactive DFGin None in-in none-out LIE Type1 5 - 352 None None 11
Mus musculus MK14_MOUSE 8ACOAAA 2.65 Inactive DFGin None in-in none-none SB2 Type1 4 - 352 None None 15
Mus musculus MK14_MOUSE 5R9UA 1.67 Inactive DFGin None in-in out-out JMM Type1 5 - 352 None None 3
Mus musculus MK14_MOUSE 8EFJA 2.31 Inactive DFGin None in-in out-out WHQ Type1 5 - 360 None None 8
Mus musculus MK14_MOUSE 2EWAA 2.1 Inactive DFGin None in-in none-none SB2 Type1 5 - 354 None None 14
Mus musculus MK14_MOUSE 6YCUA 1.35 Inactive DFGin None in-in out-out SB4 OKZ Type1 Allosteric 6 - 359 C162S None 7
Mus musculus MK14_MOUSE 5LARA 1.5 Inactive DFGout BBAminus in-in out-out 6SH Type2 4 - 353 None None 0
Mus musculus MK14_MOUSE 6Y4TA 1.98 Inactive DFGout BBAminus in-in none-out O8W Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6Y4UA 1.86 Inactive DFGout BBAminus in-in none-out O98 Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6Y4VA 1.75 Inactive DFGout BBAminus in-in out-out O8Z Type2 5 - 355 None None 8
Mus musculus MK14_MOUSE 6Y4WA 1.86 Inactive DFGout BBAminus in-out none-out O8T Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6Y4XA 1.6 Inactive DFGout BBAminus out-out none-out O8Q Type2 1 - 360 None None 9
Mus musculus MK14_MOUSE 6Y6VA 2.1 Inactive DFGout BBAminus in-out none-out OE5 Type2 4 - 353 None None 13
Mus musculus MK14_MOUSE 6YJCA 1.741 Inactive DFGout BBAminus in-in none-out OSZ Type2 4 - 352 None None 12
Mus musculus MK14_MOUSE 6YK7A 1.9 Inactive DFGout BBAminus in-in none-out OU2 Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6ZWRA 1.9 Inactive DFGout BBAminus in-in none-out OEB Type2 5 - 353 None None 11
Mus musculus MK14_MOUSE 7BDQA 2.75 Inactive DFGout BBAminus in-none none-out TJZ Type2 5 - 353 None None 13
Mus musculus MK14_MOUSE 7BE4A 2.1 Inactive DFGout BBAminus in-out none-out TK5 Type2 4 - 352 None None 12
Mus musculus MK14_MOUSE 7BE5A 1.8 Inactive DFGout BBAminus in-in none-out TKB Type2 4 - 352 None None 13
Mus musculus MK14_MOUSE 2PUUA 2.5 Inactive DFGout BBAminus in-out none-out G2G Type2 5 - 352 N14A None 12
Mus musculus MK14_MOUSE 3P5KA 2.09 Inactive DFGout BBAminus in-in none-out P5K Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P78A 2.3 Inactive DFGout BBAminus in-in none-out P78 Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P79A 2.1 Inactive DFGout BBAminus in-in none-out P79 Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P7AA 2.31 Inactive DFGout BBAminus in-in none-out P7A Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P7BA 1.9 Inactive DFGout BBAminus in-in none-out P7B Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P7CA 2.3 Inactive DFGout BBAminus in-in none-out P7C Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 7BDOA 2.7 Inactive DFGout None in-out none-out TBK Type2 5 - 353 None None 12

MAPK14 (Mitogen-activated protein kinase 14)

Group: CMGC
Total number of chains: 132
Spatial Dihedral Chains Representative
DFGin BLAminus 7 3PY3A
DFGin ABAminus 1 7PVUA
DFGin BLBminus 70 5R97A
DFGin BLBplus 22 4LOOA
DFGin None 11 5R9UA
DFGout BBAminus 20 5LARA
DFGout None 1 7BDOA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Mus musculus MK14_MOUSE 7PVUA 2.154 Inactive DFGin ABAminus out-out none-out No_ligand No_ligand 5 - 353 None None 12
Mus musculus MK14_MOUSE 2OZAB 2.7 None DFGin BLAminus out-out none-out No_ligand No_ligand 6 - 353 None None 8
Mus musculus MK14_MOUSE 3PY3A 2.1 Inactive DFGin BLAminus out-out in-out No_ligand No_ligand 1 - 354 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZE 2.6 Active DFGin BLAminus in-in in-in AGS Type1 4 - 353 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZF 2.6 Active DFGin BLAminus in-in in-in AGS Type1 5 - 353 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZG 2.6 Inactive DFGin BLAminus in-out in-in AGS Type1 5 - 353 None X180,X182 0
Mus musculus MK14_MOUSE 5NZZH 2.6 None DFGin BLAminus in-none in-in AGS Type1 5 - 352 None X180,X182 0
Mus musculus MK14_MOUSE 4TYHB 3.0 None DFGin BLAminus out-out none-out 39G Type1.5_Back 6 - 353 None None 8
Mus musculus MK14_MOUSE 5R8VA 1.479 Inactive DFGin BLBminus in-in none-out SLV Allosteric 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R8WA 1.5 Inactive DFGin BLBminus in-in out-out JND Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R8XA 1.73 Inactive DFGin BLBminus in-in out-out SLY Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R93A 1.489 Inactive DFGin BLBminus in-in none-out SOJ Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R94A 1.45 Inactive DFGin BLBminus in-in none-out SOV Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R95A 1.59 Inactive DFGin BLBminus in-in none-out SQ4 Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R96A 1.767 Inactive DFGin BLBminus in-in none-out SQ7 Allosteric 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R98A 1.68 Inactive DFGin BLBminus in-in out-out SQG Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9AA 1.53 Inactive DFGin BLBminus in-in out-out SQM Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9BA 1.657 Inactive DFGin BLBminus in-in none-out JGM Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 5R9GA 1.73 Inactive DFGin BLBminus in-in out-out RGY Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9HA 1.49 Inactive DFGin BLBminus in-in none-out SQV Allosteric 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R9OA 1.6 Inactive DFGin BLBminus in-in out-out 54F Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9SA 1.7 Inactive DFGin BLBminus in-in out-out A9B Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9TA 1.8 Inactive DFGin BLBminus in-in out-out 6T5 Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9VA 1.45 Inactive DFGin BLBminus in-in out-out SSY Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9XA 1.72 Inactive DFGin BLBminus in-in out-out NZ4 Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9ZA 1.66 Inactive DFGin BLBminus in-in out-out AYS Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA3A 1.57 Inactive DFGin BLBminus in-in out-out SVD Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA4A 1.59 Inactive DFGin BLBminus in-in out-out SVG Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA5A 1.54 Inactive DFGin BLBminus in-in out-out SVJ Allosteric 5 - 352 None None 0
Mus musculus MK14_MOUSE 6SOIA 1.55 Inactive DFGin BLBminus in-in none-out LOK Allosteric 4 - 352 None None 1
Mus musculus MK14_MOUSE 6SO1A 1.66 Inactive DFGin BLBminus in-in none-out LO5 Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 6SO2A 1.6 Inactive DFGin BLBminus in-in none-out JGG Allosteric 4 - 352 None None 2
Mus musculus MK14_MOUSE 6SO4A 1.51 Inactive DFGin BLBminus in-in none-out LO8 Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 6SODA 1.87 Inactive DFGin BLBminus in-none none-out LOE Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 6SOTA 1.54 Inactive DFGin BLBminus in-in none-out LOQ Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 5R9MA 1.809 Inactive DFGin BLBminus in-in none-out A7K A7K Allosteric Allosteric 5 - 352 None None 2
Mus musculus MK14_MOUSE 1LEWA 2.3 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 5 - 354 None None 9
Mus musculus MK14_MOUSE 1LEZA 2.3 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand 4 - 353 None None 7
Mus musculus MK14_MOUSE 4KA3A 2.707 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand 4 - 354 None None 11
Mus musculus MK14_MOUSE 3P4KA 2.304 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand 4 - 353 S28A None 12
Mus musculus MK14_MOUSE 5UOJA 2.1 Inactive DFGin BLBminus out-out none-out No_ligand No_ligand 5 - 353 None None 6
Mus musculus MK14_MOUSE 7Z9TAAA 2.6 Inactive DFGin BLBminus in-out out-out 87B Type1 5 - 353 None None 0
Mus musculus MK14_MOUSE 5R90A 1.619 Inactive DFGin BLBminus in-in none-out SNJ Type1 4 - 352 None None 2
Mus musculus MK14_MOUSE 5R91A 1.731 Inactive DFGin BLBminus in-in out-out SNV Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R92A 1.66 Inactive DFGin BLBminus in-in none-out SO7 Type1 4 - 352 None None 2
Mus musculus MK14_MOUSE 5R99A 1.89 Inactive DFGin BLBminus in-in out-out SU7 Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9CA 1.74 Inactive DFGin BLBminus in-in out-out 7ZC Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9FA 1.986 Inactive DFGin BLBminus in-in none-out SQP Type1 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R9IA 1.813 Inactive DFGin BLBminus in-in none-out SQY Type1 5 - 352 None None 2
Mus musculus MK14_MOUSE 5R9JA 1.52 Inactive DFGin BLBminus in-in none-out LXS Type1 4 - 352 None None 1
Mus musculus MK14_MOUSE 5R9LA 1.47 Inactive DFGin BLBminus in-in none-out SRJ Type1 4 - 352 None None 2
Mus musculus MK14_MOUSE 5R9NA 1.688 Inactive DFGin BLBminus out-out out-out JFS Type1 4 - 352 None None 0
Mus musculus MK14_MOUSE 5R9PA 1.72 Inactive DFGin BLBminus in-in out-out SFY Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9RA 1.76 Inactive DFGin BLBminus in-in out-out K3D Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9YA 1.57 Inactive DFGin BLBminus in-in none-out SU7 Type1 5 - 352 None None 2
Mus musculus MK14_MOUSE 5RA0A 1.91 Inactive DFGin BLBminus in-out out-out JFS Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA2A 1.57 Inactive DFGin BLBminus in-in out-out SV4 Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA6A 1.86 Inactive DFGin BLBminus in-in out-out SVM Type1 5 - 352 None None 0
Mus musculus MK14_MOUSE 4LOPB 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 353 None None 0
Mus musculus MK14_MOUSE 4LOPC 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 4LOQA 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 3 - 354 None None 0
Mus musculus MK14_MOUSE 4LOQB 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 4LOQC 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 353 None None 0
Mus musculus MK14_MOUSE 4LOQD 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1 4 - 354 None None 0
Mus musculus MK14_MOUSE 5R8UA 1.48 Inactive DFGin BLBminus in-in out-out SLS Type1.5_Back 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA7A 1.92 Inactive DFGin BLBminus in-in out-out SW7 Type1.5_Back 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA8A 1.78 Inactive DFGin BLBminus in-in out-out 2O6 Type1.5_Back 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R8YA 1.679 Inactive DFGin BLBminus in-in out-out SMV Type3 4 - 352 None None 0
Mus musculus MK14_MOUSE 5R8ZA 1.65 Inactive DFGin BLBminus in-in out-out SN4 Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R97A 1.438 Inactive DFGin BLBminus in-in out-out RUY Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9DA 1.69 Inactive DFGin BLBminus in-in out-out N9J Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9EA 1.775 Inactive DFGin BLBminus in-in none-out S7S Type3 5 - 352 None None 1
Mus musculus MK14_MOUSE 5R9KA 1.498 Inactive DFGin BLBminus in-in out-out SR4 Type3 4 - 352 None None 0
Mus musculus MK14_MOUSE 5R9QA 1.645 Inactive DFGin BLBminus in-in out-out LVD Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5R9WA 1.89 Inactive DFGin BLBminus in-in out-out STV Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA1A 1.61 Inactive DFGin BLBminus in-in out-out PO6 Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 5RA9A 1.68 Inactive DFGin BLBminus in-in out-out SWD Type3 5 - 352 None None 0
Mus musculus MK14_MOUSE 7Z9TBBB 2.6 Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric 4 - 353 None None 0
Mus musculus MK14_MOUSE 6Y7ZA 1.35 Inactive DFGin BLBplus in-in none-out OG2 SB4 Allosteric Type1 5 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y80A 1.24 Inactive DFGin BLBplus in-in out-out OFZ SB4 Allosteric Type1 5 - 359 C162S None 8
Mus musculus MK14_MOUSE 6Y85A 1.58 Inactive DFGin BLBplus in-in none-out OG8 SB4 Allosteric Type1 5 - 359 C162S None 11
Mus musculus MK14_MOUSE 1YWRA 1.95 Inactive DFGin BLBplus in-in out-out LI9 Type1 5 - 352 T180A,Y182F None 9
Mus musculus MK14_MOUSE 2GHLA 2.099 Inactive DFGin BLBplus in-in out-out LIB Type1 5 - 352 T180A,Y182F None 10
Mus musculus MK14_MOUSE 7PVUB 2.154 Inactive DFGin BLBplus in-out none-none 8DI Type1 5 - 353 None None 13
Mus musculus MK14_MOUSE 6Y8HA 1.37 Inactive DFGin BLBplus in-in none-out SB4 Type1 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 8ACMAAA 2.14 Inactive DFGin BLBplus in-in none-none SB2 Type1 4 - 353 None None 13
Mus musculus MK14_MOUSE 4LOOA 1.95 Inactive DFGin BLBplus in-in out-out SB4 Type1 5 - 353 None None 0
Mus musculus MK14_MOUSE 4LOPA 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 4LOPD 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1 3 - 353 None None 0
Mus musculus MK14_MOUSE 5O90A 2.49 Inactive DFGin BLBplus in-in none-out SB4 Type1 5 - 353 T185G None 9
Mus musculus MK14_MOUSE 6Y7WA 1.39 Inactive DFGin BLBplus in-in none-out SB4 OFW Type1 Allosteric 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y7XA 1.45 Inactive DFGin BLBplus in-in none-out SB4 OFQ Type1 Allosteric 5 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y81A 1.54 Inactive DFGin BLBplus in-in none-out SB4 OG5 Type1 Allosteric 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 6Y82A 1.44 Inactive DFGin BLBplus in-in out-out SB4 308 Type1 Allosteric 6 - 360 C162S None 7
Mus musculus MK14_MOUSE 6YCWA 1.34 Inactive DFGin BLBplus in-in none-out SB4 OL8 Type1 Allosteric 6 - 359 C162S None 10
Mus musculus MK14_MOUSE 6SOVA 1.31 Inactive DFGin BLBplus in-in none-out SB4 LOT LOW Type1 Allosteric Allosteric 6 - 359 None None 9
Mus musculus MK14_MOUSE 6SP9A 1.22 Inactive DFGin BLBplus in-in out-out SB4 LOT LOT Type1 Allosteric Allosteric 5 - 359 None None 7
Mus musculus MK14_MOUSE 6Y7YA 1.51 Inactive DFGin BLBplus in-in none-out SB4 OFQ LOT LOT Type1 Allosteric Allosteric Allosteric 6 - 359 C162S None 11
Mus musculus MK14_MOUSE 6SPLA 1.38 Inactive DFGin BLBplus in-in out-out SB4 LOW LOW LOW Type1 Allosteric Type1 Allosteric 6 - 359 None None 9
Mus musculus MK14_MOUSE 7Z6IAAA 2.25 Inactive DFGin BLBplus in-in out-out IIM 87B Type1 Type1 5 - 354 C162S None 0
Mus musculus MK14_MOUSE 6SOUA 1.5 Inactive DFGin None in-in out-out LPZ LPZ Allosteric Type1 5 - 352 None None 3
Mus musculus MK14_MOUSE 3TG1A 2.71 Inactive DFGin None in-in none-out No_ligand No_ligand 5 - 352 None None 14
Mus musculus MK14_MOUSE 2GHMA 2.35 Inactive DFGin None in-in none-out LIC Type1 5 - 352 T180A,Y182F None 11
Mus musculus MK14_MOUSE 1YW2A 2.01 Inactive DFGin None in-in out-out PGJ Type1 4 - 353 T180A,Y182F None 9
Mus musculus MK14_MOUSE 2GTMA 1.9 Inactive DFGin None in-in out-out LID Type1 5 - 352 None None 4
Mus musculus MK14_MOUSE 2GTNA 1.8 Inactive DFGin None in-in none-out LIE Type1 5 - 352 None None 11
Mus musculus MK14_MOUSE 8ACOAAA 2.65 Inactive DFGin None in-in none-none SB2 Type1 4 - 352 None None 15
Mus musculus MK14_MOUSE 5R9UA 1.67 Inactive DFGin None in-in out-out JMM Type1 5 - 352 None None 3
Mus musculus MK14_MOUSE 8EFJA 2.31 Inactive DFGin None in-in out-out WHQ Type1 5 - 360 None None 8
Mus musculus MK14_MOUSE 2EWAA 2.1 Inactive DFGin None in-in none-none SB2 Type1 5 - 354 None None 14
Mus musculus MK14_MOUSE 6YCUA 1.35 Inactive DFGin None in-in out-out SB4 OKZ Type1 Allosteric 6 - 359 C162S None 7
Mus musculus MK14_MOUSE 5LARA 1.5 Inactive DFGout BBAminus in-in out-out 6SH Type2 4 - 353 None None 0
Mus musculus MK14_MOUSE 6Y4TA 1.98 Inactive DFGout BBAminus in-in none-out O8W Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6Y4UA 1.86 Inactive DFGout BBAminus in-in none-out O98 Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6Y4VA 1.75 Inactive DFGout BBAminus in-in out-out O8Z Type2 5 - 355 None None 8
Mus musculus MK14_MOUSE 6Y4WA 1.86 Inactive DFGout BBAminus in-out none-out O8T Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6Y4XA 1.6 Inactive DFGout BBAminus out-out none-out O8Q Type2 1 - 360 None None 9
Mus musculus MK14_MOUSE 6Y6VA 2.1 Inactive DFGout BBAminus in-out none-out OE5 Type2 4 - 353 None None 13
Mus musculus MK14_MOUSE 6YJCA 1.741 Inactive DFGout BBAminus in-in none-out OSZ Type2 4 - 352 None None 12
Mus musculus MK14_MOUSE 6YK7A 1.9 Inactive DFGout BBAminus in-in none-out OU2 Type2 5 - 355 None None 10
Mus musculus MK14_MOUSE 6ZWRA 1.9 Inactive DFGout BBAminus in-in none-out OEB Type2 5 - 353 None None 11
Mus musculus MK14_MOUSE 7BDQA 2.75 Inactive DFGout BBAminus in-none none-out TJZ Type2 5 - 353 None None 13
Mus musculus MK14_MOUSE 7BE4A 2.1 Inactive DFGout BBAminus in-out none-out TK5 Type2 4 - 352 None None 12
Mus musculus MK14_MOUSE 7BE5A 1.8 Inactive DFGout BBAminus in-in none-out TKB Type2 4 - 352 None None 13
Mus musculus MK14_MOUSE 2PUUA 2.5 Inactive DFGout BBAminus in-out none-out G2G Type2 5 - 352 N14A None 12
Mus musculus MK14_MOUSE 3P5KA 2.09 Inactive DFGout BBAminus in-in none-out P5K Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P78A 2.3 Inactive DFGout BBAminus in-in none-out P78 Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P79A 2.1 Inactive DFGout BBAminus in-in none-out P79 Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P7AA 2.31 Inactive DFGout BBAminus in-in none-out P7A Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P7BA 1.9 Inactive DFGout BBAminus in-in none-out P7B Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 3P7CA 2.3 Inactive DFGout BBAminus in-in none-out P7C Type3 5 - 352 None None 13
Mus musculus MK14_MOUSE 7BDOA 2.7 Inactive DFGout None in-out none-out TBK Type2 5 - 353 None None 12