RPS6KA6 (Ribosomal protein S6 kinase alpha-6)

RPS6KA6 has two kinase domains in its sequence, labeled here as RPS6KA6-1 and RPS6KA6-2. Structures with both domains are given in the last table and labeled as RPS6KA6-12.
Domain_1: RPS6KA6-1
Group: AGC
Example Uniprot: KS6A6_HUMAN
Domain boundary: 73 - 330

Total number of chains: 7
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q9UK32-K1A
DFGin None 2 6G77A
DFGinter None 4 6G76A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment

Database table as tsv
Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KS6A6_HUMAN AF-Q9UK32-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 65 - 338 None None 0
Homo sapiens KS6A6_HUMAN 6G77A 2.499 Inactive DFGin None none-none out-in ANP ANP Allosteric Type1 51 - 349 None None 0
Homo sapiens KS6A6_HUMAN 6G77B 2.499 Inactive DFGin None none-none out-in ANP ANP Allosteric Type1 51 - 349 None None 0
Homo sapiens KS6A6_HUMAN 6G76B 3.0 Inactive DFGinter None none-none out-none ANP Type1 51 - 349 None X232 11
Homo sapiens KS6A6_HUMAN 6G78A 2.5 Inactive DFGinter None none-none out-out ANP Type1 51 - 349 S232E None 8
Homo sapiens KS6A6_HUMAN 6G78B 2.5 Inactive DFGinter None none-none out-out ANP Type1 51 - 349 S232E None 10
Homo sapiens KS6A6_HUMAN 6G76A 3.0 Inactive DFGinter None none-none out-in ANP ANP Type1 Allosteric 51 - 349 None X232 0

RPS6KA6 (Ribosomal protein S6 kinase alpha-6)

Domain_2: RPS6KA6-2
Group: CAMK
Example Uniprot: KS6A6_HUMAN
Domain boundary: 426 - 683

Total number of chains in: 1
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-Q9UK32-K2A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment

Database table as tsv
Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KS6A6_HUMAN AF-Q9UK32-K2A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 418 - 691 None None 0

RPS6KA6 (Ribosomal protein S6 kinase alpha-6)

Domain_12: RPS6KA6-12
Total number of chains in: 0. Analysis of 2nd kinase domain given in table below.