RPS6KA5 (Ribosomal protein S6 kinase alpha-5)

RPS6KA5 has two kinase domains in its sequence, labeled here as RPS6KA5-1 and RPS6KA5-2. Structures with both domains are given in the last table and labeled as RPS6KA5-12.
Domain_1: RPS6KA5-1
Group: AGC
Example Uniprot: KS6A5_HUMAN
Domain boundary: 49 - 318

Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLAminus 1 AF-O75582-K1A
DFGinter None 1 1VZOA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment

Database table as tsv
Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KS6A5_HUMAN AF-O75582-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 41 - 326 None None 0
Homo sapiens KS6A5_HUMAN 1VZOA 1.8 Inactive DFGinter None out-out out-out No_ligand No_ligand 24 - 345 S212D None 0

RPS6KA5 (Ribosomal protein S6 kinase alpha-5)

Domain_2: RPS6KA5-2
Group: CAMK
Example Uniprot: KS6A5_HUMAN
Domain boundary: 426 - 687

Total number of chains in: 14
Spatial Dihedral Chains Representative
DFGin BLAminus 14 AF-O75582-K2A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment

Database table as tsv
Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KS6A5_HUMAN AF-O75582-K2A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 415 - 695 None None 0
Homo sapiens KS6A5_HUMAN 3KN6A 2.0 None DFGin BLAminus in-in in-none No_ligand No_ligand 415 - 729 None None 0
Homo sapiens KS6A5_HUMAN 3KN6B 2.0 None DFGin BLAminus in-in in-none No_ligand No_ligand 415 - 729 None None 0
Homo sapiens KS6A5_HUMAN 3KN5A 2.4 None DFGin BLAminus in-in in-none ANP Type1 415 - 729 None None 0
Homo sapiens KS6A5_HUMAN 3KN5B 2.4 None DFGin BLAminus in-in in-none ANP Type1 415 - 729 None None 0
Homo sapiens KS6A5_HUMAN 7UP4A 3.0 None DFGin BLAminus in-in in-none O1K Type1 415 - 723 None None 0
Homo sapiens KS6A5_HUMAN 7UP4B 3.0 None DFGin BLAminus in-in in-none O1K Type1 415 - 728 None None 0
Homo sapiens KS6A5_HUMAN 7UP5A 2.8 None DFGin BLAminus in-in in-none O1R Type1 415 - 723 None None 0
Homo sapiens KS6A5_HUMAN 7UP5B 2.8 None DFGin BLAminus in-in in-none O1R Type1 415 - 728 None None 0
Homo sapiens KS6A5_HUMAN 7UP7A 2.8 None DFGin BLAminus in-in in-none 1LE Type1 415 - 725 None None 0
Homo sapiens KS6A5_HUMAN 7UP7B 2.8 None DFGin BLAminus in-in in-none 1LE Type1 416 - 728 None None 0
Homo sapiens KS6A5_HUMAN 7UP8A 2.9 None DFGin BLAminus in-in in-none O10 Type1 415 - 723 None None 0
Homo sapiens KS6A5_HUMAN 7UP8B 2.9 None DFGin BLAminus in-in in-none O10 Type1 415 - 727 None None 0
Homo sapiens KS6A5_HUMAN 7UP6A 2.6 None DFGin BLAminus in-in in-none SUU OXM OXM Type1 Allosteric Allosteric 416 - 707 None None 0

RPS6KA5 (Ribosomal protein S6 kinase alpha-5)

Domain_12: RPS6KA5-12
Total number of chains in: 0. Analysis of 2nd kinase domain given in table below.