Protein kinases in complex with SB4

Total number of genes: 1
Total number of chains: 1
Spatial Dihedral Chains Representative
DFGin BLBminus 1 1BL7A
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BL7A 2.5 Inactive DFGin BLBminus in-in out-out SB4 Type1

Protein kinases in complex with SB4

Total number of genes: 2
Total number of chains: 26
Spatial Dihedral Chains Representative
DFGin BLAminus 1 3ERKA
DFGin BLBminus 7 4LOPB
DFGin BLBplus 17 4LOOA
DFGin None 1 6YCUA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BL7A 2.5 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPB 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPC 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQA 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQB 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQC 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQD 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7ZA 1.35 Inactive DFGin BLBplus in-in none-out OG2 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y80A 1.24 Inactive DFGin BLBplus in-in out-out OFZ SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y85A 1.58 Inactive DFGin BLBplus in-in none-out OG8 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y8HA 1.37 Inactive DFGin BLBplus in-in none-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOOA 1.95 Inactive DFGin BLBplus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPA 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPD 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5O90A 2.49 Inactive DFGin BLBplus in-in none-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7WA 1.39 Inactive DFGin BLBplus in-in none-out SB4 OFW Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7XA 1.45 Inactive DFGin BLBplus in-in none-out SB4 OFQ Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y81A 1.54 Inactive DFGin BLBplus in-in none-out SB4 OG5 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y82A 1.44 Inactive DFGin BLBplus in-in out-out SB4 308 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCWA 1.34 Inactive DFGin BLBplus in-in none-out SB4 OL8 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOVA 1.31 Inactive DFGin BLBplus in-in none-out SB4 LOT LOW Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SP9A 1.22 Inactive DFGin BLBplus in-in out-out SB4 LOT LOT Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7YA 1.51 Inactive DFGin BLBplus in-in none-out SB4 OFQ LOT LOT Type1 Allosteric Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SPLA 1.38 Inactive DFGin BLBplus in-in out-out SB4 LOW LOW LOW Type1 Allosteric Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCUA 1.35 Inactive DFGin None in-in out-out SB4 OKZ Type1 Allosteric
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 3ERKA 2.1 Inactive DFGin BLAminus out-out in-in SB4 Type1

Protein kinases in complex with SB4

Total number of genes: 2
Total number of chains: 25
Spatial Dihedral Chains Representative
DFGin BLAminus 1 3ERKA
DFGin BLBminus 6 4LOPB
DFGin BLBplus 17 4LOOA
DFGin None 1 6YCUA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPB 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPC 2.049 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQA 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQB 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQC 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQD 2.319 Inactive DFGin BLBminus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7ZA 1.35 Inactive DFGin BLBplus in-in none-out OG2 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y80A 1.24 Inactive DFGin BLBplus in-in out-out OFZ SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y85A 1.58 Inactive DFGin BLBplus in-in none-out OG8 SB4 Allosteric Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y8HA 1.37 Inactive DFGin BLBplus in-in none-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOOA 1.95 Inactive DFGin BLBplus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPA 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPD 2.049 Inactive DFGin BLBplus in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5O90A 2.49 Inactive DFGin BLBplus in-in none-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7WA 1.39 Inactive DFGin BLBplus in-in none-out SB4 OFW Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7XA 1.45 Inactive DFGin BLBplus in-in none-out SB4 OFQ Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y81A 1.54 Inactive DFGin BLBplus in-in none-out SB4 OG5 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y82A 1.44 Inactive DFGin BLBplus in-in out-out SB4 308 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCWA 1.34 Inactive DFGin BLBplus in-in none-out SB4 OL8 Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOVA 1.31 Inactive DFGin BLBplus in-in none-out SB4 LOT LOW Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SP9A 1.22 Inactive DFGin BLBplus in-in out-out SB4 LOT LOT Type1 Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6Y7YA 1.51 Inactive DFGin BLBplus in-in none-out SB4 OFQ LOT LOT Type1 Allosteric Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SPLA 1.38 Inactive DFGin BLBplus in-in out-out SB4 LOW LOW LOW Type1 Allosteric Type1 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6YCUA 1.35 Inactive DFGin None in-in out-out SB4 OKZ Type1 Allosteric
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 3ERKA 2.1 Inactive DFGin BLAminus out-out in-in SB4 Type1