| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | BLBplus | out-out | out-out | 746 | Type1 | 395 - 659 | 0 |
| B | Inactive | DFGin | BLBplus | out-out | out-out | 746 PE4 | Type1 Allosteric | 395 - 659 | 0 |
| C | Inactive | DFGin | BLBplus | out-out | out-out | 746 PE4 | Type1 Allosteric | 395 - 659 | 0 |
| D | Inactive | DFGin | BLBplus | out-out | out-out | 746 | Type1 | 395 - 659 | 0 |
Representative sequence - Chain D
403 413 423 433
aWEIDPKDLT FLKELGTGQF GVVKYGKWRG QYDVAIKMIK
443 453 463 473
EGSMSEDEFI EEAKVMMNLS HEKLVQLYGV CTKQRPIFII
483 493 503 513
TEYMANGCLL NYLREMRHRF QTQQLLEMCK DVCEAMEYLE
523 533 543 553
SKQFLHRDLA ARNCLVNDQG VVKVSDFGMT RFVLDDEYTS
563 573 583 593
STGTKFPVKW ASPEVLMYSK FSSKSDIWAF GVLMWEIYSL
603 613 623 633
GKMPYERFTN SETAEHIAQG LRLPRPHLAS ERVYAIMYSC
643 653
WHEKADERPT FKILLSNILD VMDEES