CDC7 (Cell division cycle 7-related protein kinase)

Group: OTHER

Uniprot: CDC7_HUMAN

Domain boundary: 58 - 569

Total number of chains: 10

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	10	AF-O00311-K1A

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-O00311-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	50 - 574	None	None	0
4F99A	2.33	None	DFGin	BLAminus	in-in	in-none	ADP	Type1	41 - 572	None	None	20
4F9AA	2.17	None	DFGin	BLAminus	in-in	in-none	ADP	Type1	39 - 572	None	None	20
4F9AC	2.17	None	DFGin	BLAminus	in-in	in-none	ADP	Type1	37 - 572	None	None	20
4F9BA	2.5	None	DFGin	BLAminus	in-in	in-none	0SY	Type1	39 - 572	None	None	17
4F9BC	2.5	None	DFGin	BLAminus	in-in	in-none	0SY	Type1	37 - 572	None	None	21
4F9CA	2.08	None	DFGin	BLAminus	in-in	in-none	0SX	Type1	41 - 572	None	None	26
6YA7A	1.67	Active	DFGin	BLAminus	in-in	in-in	ADP	Type1	39 - 573	None	None	5
6YA8A	1.79	Active	DFGin	BLAminus	in-in	in-in	ADP BEF	Type1 Allosteric	38 - 572	None	None	13
6YA6A	1.44	Active	DFGin	BLAminus	in-in	in-in	0SX BO3	Type1 Type1	38 - 573	None	None	12

CDC7 (Cell division cycle 7-related protein kinase)

Group: OTHER

Total number of chains: 15

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	11	AF-O00311-K1A
DFGin	BLAplus	1	7P5Z1
DFGin	ABAminus	3	7PT68

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	CDC7_HUMAN	AF-O00311-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	50 - 574	None	None	0
Homo sapiens	CDC7_HUMAN	4F99A	2.33	None	DFGin	BLAminus	in-in	in-none	ADP	Type1	41 - 572	None	None	20
Homo sapiens	CDC7_HUMAN	4F9AA	2.17	None	DFGin	BLAminus	in-in	in-none	ADP	Type1	39 - 572	None	None	20
Homo sapiens	CDC7_HUMAN	4F9AC	2.17	None	DFGin	BLAminus	in-in	in-none	ADP	Type1	37 - 572	None	None	20
Homo sapiens	CDC7_HUMAN	4F9BA	2.5	None	DFGin	BLAminus	in-in	in-none	0SY	Type1	39 - 572	None	None	17
Homo sapiens	CDC7_HUMAN	4F9BC	2.5	None	DFGin	BLAminus	in-in	in-none	0SY	Type1	37 - 572	None	None	21
Homo sapiens	CDC7_HUMAN	4F9CA	2.08	None	DFGin	BLAminus	in-in	in-none	0SX	Type1	41 - 572	None	None	26
Homo sapiens	CDC7_HUMAN	6YA7A	1.67	Active	DFGin	BLAminus	in-in	in-in	ADP	Type1	39 - 573	None	None	5
Homo sapiens	CDC7_HUMAN	6YA8A	1.79	Active	DFGin	BLAminus	in-in	in-in	ADP BEF	Type1 Allosteric	38 - 572	None	None	13
Homo sapiens	CDC7_HUMAN	6YA6A	1.44	Active	DFGin	BLAminus	in-in	in-in	0SX BO3	Type1 Type1	38 - 573	None	None	12
Saccharomyces cerevisiae	CDC7_YEAST	7PT68	3.2	Inactive	DFGin	ABAminus	in-in	in-in	AGS	Type1	10 - 475	None	None	46
Saccharomyces cerevisiae	CDC7_YEAST	7PT6H	3.2	Inactive	DFGin	ABAminus	in-in	in-in	AGS	Type1	10 - 475	None	None	46
Saccharomyces cerevisiae	CDC7_YEAST	7PT78	3.8	Inactive	DFGin	ABAminus	in-out	in-in	ADP BEF	Type1 Allosteric	10 - 475	None	None	46
Saccharomyces cerevisiae	CDC7_YEAST	7V3VH	2.9	Active	DFGin	BLAminus	in-in	in-in	AGS	Type1	12 - 473	None	None	62
Saccharomyces cerevisiae	CDC7_YEAST	7P5Z1	3.3	Inactive	DFGin	BLAplus	in-out	in-in	No_ligand	No_ligand	16 - 471	None	None	46

CDC7 (Cell division cycle 7-related protein kinase)

Group: OTHER

Total number of chains: 5

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	1	7V3VH
DFGin	BLAplus	1	7P5Z1
DFGin	ABAminus	3	7PT68

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Saccharomyces cerevisiae	CDC7_YEAST	7PT68	3.2	Inactive	DFGin	ABAminus	in-in	in-in	AGS	Type1	10 - 475	None	None	46
Saccharomyces cerevisiae	CDC7_YEAST	7PT6H	3.2	Inactive	DFGin	ABAminus	in-in	in-in	AGS	Type1	10 - 475	None	None	46
Saccharomyces cerevisiae	CDC7_YEAST	7PT78	3.8	Inactive	DFGin	ABAminus	in-out	in-in	ADP BEF	Type1 Allosteric	10 - 475	None	None	46
Saccharomyces cerevisiae	CDC7_YEAST	7V3VH	2.9	Active	DFGin	BLAminus	in-in	in-in	AGS	Type1	12 - 473	None	None	62
Saccharomyces cerevisiae	CDC7_YEAST	7P5Z1	3.3	Inactive	DFGin	BLAplus	in-out	in-in	No_ligand	No_ligand	16 - 471	None	None	46