EGFR (Epidermal growth factor receptor)

Group: TYR
Uniprot: EGFR_HUMAN
Domain boundary: 712 - 970


Total number of chains: 439
Spatial Dihedral Chains Representative
DFGin BLAminus 154 AF-P00533-K1A
DFGin BLAplus 11 8A2AA
DFGin ABAminus 4 3IKAA
DFGin BLBminus 4 8A2DA
DFGin BLBplus 146 6V66D
DFGin BLBtrans 81 6V66A
DFGin None 13 4RIYD
DFGinter None 8 2JIUB
DFGout BBAminus 12 5HG8A
DFGout None 5 4I1ZA
None None 1 8DSWA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
3IKAA 2.9 Inactive DFGin ABAminus in-in in-in 0UN Type1 696 - 1020 T790M None 0
7ER2A 2.662 Inactive DFGin ABAminus in-in in-in JAU Type1 697 - 1018 T790M,C797S None 7
4LL0A 4.0 Inactive DFGin ABAminus in-out in-in YUN Type1 697 - 1017 T790M,L858R None 13
4LL0B 4.0 Inactive DFGin ABAminus in-out in-in YUN Type1 698 - 1017 T790M,L858R None 14
8HV4A 2.2 Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1 696 - 1020 E865A,E866A,K867A None 3
8HV6A 2.2 Active DFGin BLAminus in-in in-in PE5 N86 Allosteric Type1 696 - 1020 E865A,E866A,K867A None 0
8HV7A 2.69 Active DFGin BLAminus in-in in-in PE5 N8O Allosteric Type1 696 - 1019 E865A,E866A,K867A None 6
8HV8A 2.4 Active DFGin BLAminus in-in in-in PE5 N99 Allosteric Type1 696 - 1019 C797S,E865A,E866A,K867A None 0
8HV9A 2.5 Active DFGin BLAminus in-in in-in PE5 N9L Allosteric Type1 696 - 1019 E865A,E866A,K867A None 0
8HV1A 2.4 Active DFGin BLAminus in-in in-in PE5 N6N Allosteric Type1 696 - 1019 E865A,E866A,K867A None 0
8HV3A 2.4 Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1 696 - 1020 E865A,E866A,K867A None 0
8HV5A 2.2 Active DFGin BLAminus in-in in-in PE5 N7C Allosteric Type1 696 - 1019 E865A,E866A,K867A None 0
2JITA 3.1 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1016 T790M None 0
3UG1A 2.75 Active DFGin BLAminus in-in in-in No_ligand No_ligand 697 - 1018 G719S,T790M None 0
AF-P00533-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 704 - 978 None None 0
2J5EA 3.1 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1020 None None 0
2GS2A 2.8 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1018 None None 0
2GS6A 2.6 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1019 None None 0
4WRGA 1.9 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1019 None None 2
7SI1A 1.6 Active DFGin BLAminus in-in in-in No_ligand No_ligand 695 - 1020 None None 0
4TKSA 3.202 Active DFGin BLAminus in-in in-in No_ligand No_ligand 697 - 1019 None None 0
1M14A 2.6 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1020 None None 0
2EB2A 2.5 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1019 None None 1
4R3PA 2.905 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
4R3RA 3.25 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
5CZHA 2.8 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
5CZIA 2.6 Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
8H7XA 3.404 Active DFGin BLAminus in-in in-in 6GY Type1 697 - 1019 T790M,C797S None 0
5XGNA 3.0 Active DFGin BLAminus in-in in-in 85X Type1 697 - 1020 T790M,C797S None 0
6JRXA 2.201 Active DFGin BLAminus in-in in-in 9JO Type1 696 - 1017 T790M,C797S None 3
5J9YA 2.8 Active DFGin BLAminus in-in in-in 6HL Type1 697 - 1019 None None 3
8EMEB 3.32 None DFGin BLAminus out-out none-none ZNL Type1 702 - 1007 T790M,V948R None 19
5J9ZA 2.5 Active DFGin BLAminus in-in in-in 6HJ Type1 696 - 1020 T790M None 15
7A6IA 2.4 Inactive DFGin BLAminus out-out in-in R1W Type1 703 - 984 T790M,V948R None 0
5X2KA 3.201 Active DFGin BLAminus in-in in-in 0UN Type1 696 - 1020 T790M None 6
2JIUA 3.05 Inactive DFGin BLAminus in-out in-in AEE Type1 696 - 1016 T790M None 0
5FEQA 3.4 Active DFGin BLAminus in-in in-in 5XH Type1 697 - 1017 T790M None 5
4G5PA 3.17 Active DFGin BLAminus in-in in-in 0WN Type1 696 - 1016 T790M None 0
5GMPA 2.797 Inactive DFGin BLAminus in-in in-out F62 Type1 696 - 1019 T790M None 11
5GTZA 2.999 Active DFGin BLAminus in-in in-in 81C Type1 697 - 1020 T790M None 7
5XDKA 2.346 Active DFGin BLAminus in-in in-in 8JC Type1 696 - 1018 T790M None 0
6JX4A 2.531 Active DFGin BLAminus in-in in-in YY3 Type1 696 - 1018 T790M None 8
4WD5A 3.3 Inactive DFGin BLAminus out-out in-out 3LH Type1 694 - 1021 T790M None 0
5Y9TA 3.25 Active DFGin BLAminus in-in in-in 8RC Type1 697 - 1020 T790M None 0
3UG2A 2.5 Inactive DFGin BLAminus in-out in-in IRE Type1 697 - 1018 G719S,T790M None 0
3VJNA 2.34 Inactive DFGin BLAminus in-out in-in ANP Type1 697 - 1018 G719S,T790M None 0
7VRAA 2.41 Active DFGin BLAminus in-in in-in I0A Type1 696 - 1018 T790M,C797S None 11
7VREA 2.507 Active DFGin BLAminus in-in in-in 7VH Type1 696 - 1018 T790M,C797S None 8
6S89A 2.701 Active DFGin BLAminus in-in in-in L0Q Type1 697 - 1017 T790M,C797S,E865A,E866A,K867A None 0
6S8AA 2.6 Active DFGin BLAminus in-in in-in L0N Type1 697 - 1018 T790M,C797S,E865A,E866A,K867A None 0
7ZYMA 2.5 Active DFGin BLAminus in-in in-in 6GY Type1 696 - 1020 T790M,C797S,E865A,E866A,K867A None 0
7ZYNA 2.3 Active DFGin BLAminus in-in in-in 0UN Type1 697 - 1018 T790M,C797S,E865A,E866A,K867A None 0
7ZYPA 2.8 None DFGin BLAminus in-none in-in R25 Type1 695 - 1019 T790M,C797S,E865A,E866A,K867A None 0
7OXBA 2.56 Active DFGin BLAminus in-in in-in 35Z Type1 696 - 1019 None None 6
8WD4A 2.55 Active DFGin BLAminus in-in in-in W7W Type1 696 - 1019 T790M,C797S,L858R None 11
6LUBA 2.315 Active DFGin BLAminus in-in in-in EUX Type1 696 - 1018 T790M,C797S,L858R,E865A,E866A,K867A None 0
6LUDA 2.05 Active DFGin BLAminus in-in in-in YY3 Type1 696 - 1018 T790M,C797S,L858R,E865A,E866A,K867A None 0
8HVAA 2.77 Active DFGin BLAminus in-in in-in N9R Type1 696 - 1020 E865A,E866A,K867A None 4
6JZ0A 2.86 Active DFGin BLAminus in-in in-in CKO Type1 696 - 1019 None None 0
2ITWA 2.88 Inactive DFGin BLAminus in-out in-in ITQ Type1 696 - 1018 None None 0
2ITXA 2.98 Active DFGin BLAminus in-in in-in ANP Type1 697 - 1019 None None 4
2ITYA 3.42 Active DFGin BLAminus in-in in-in IRE Type1 697 - 1019 None None 10
2J5FA 3.0 Active DFGin BLAminus in-in in-in DJK Type1 696 - 1020 None None 8
2J6MA 3.1 Active DFGin BLAminus in-in in-in AEE Type1 697 - 1020 None None 0
6VH4A 2.8 Active DFGin BLAminus in-in in-in QQM Type1 696 - 1019 None None 3
6VHNA 2.4 Active DFGin BLAminus in-in in-in QQJ Type1 696 - 1019 None None 13
6VHPA 3.6 Active DFGin BLAminus in-in in-in QP1 Type1 696 - 1019 None None 5
8G63A 2.5 Active DFGin BLAminus in-in in-in YXT Type1 696 - 1017 None None 14
7UKVA 2.4 Active DFGin BLAminus in-in in-in ZRT Type1 696 - 1018 None None 6
5FEDA 2.651 Active DFGin BLAminus in-in in-in 5X4 Type1 697 - 1017 None None 4
7T4IA 2.61 Active DFGin BLAminus in-in in-in R28 Type1 697 - 1017 None None 0
4JQ7A 2.73 Active DFGin BLAminus in-in in-in KJQ Type1 696 - 1019 None None 0
4JQ8A 2.83 Active DFGin BLAminus in-in in-in KJ8 Type1 696 - 1019 None None 0
4JR3A 2.7 Active DFGin BLAminus in-in in-in KJR Type1 696 - 1019 None None 0
4JRVA 2.8 Active DFGin BLAminus in-in in-in KJV Type1 696 - 1019 None None 0
4LI5A 2.64 Active DFGin BLAminus in-in in-in 1WY Type1 696 - 1020 None None 0
4I23A 2.8 Active DFGin BLAminus in-in in-in 1C9 Type1 695 - 1018 None None 0
5UGBA 2.53 Active DFGin BLAminus in-in in-in 8BM Type1 695 - 1018 None None 0
7AEIA 2.65 Active DFGin BLAminus in-in in-in R85 Type1 697 - 1018 None None 0
5JEBA 3.298 Active DFGin BLAminus in-in in-in 6JS Type1 699 - 999 V948R None 0
4WKQA 1.85 Active DFGin BLAminus in-in in-in IRE Type1 696 - 1020 None None 0
4ZAUA 2.8 Active DFGin BLAminus in-in in-in YY3 Type1 698 - 1017 None None 5
5CAVA 2.73 Active DFGin BLAminus in-in in-in 4ZQ Type1 697 - 1020 None None 0
5EM8A 2.8 Active DFGin BLAminus in-in in-in 5Q4 Type1 696 - 1018 None None 2
7KXZA 2.4 Active DFGin BLAminus in-in in-in XA4 Type1 696 - 1017 None None 0
7U99A 2.5 Active DFGin BLAminus in-in in-in M0R Type1 695 - 1018 None None 0
7U9AA 2.6 Active DFGin BLAminus in-in in-in M19 Type1 695 - 1018 None None 4
8F1HA 2.8 Active DFGin BLAminus in-in in-in X9H Type1 697 - 1018 None None 0
8F1XA 2.3 Active DFGin BLAminus in-in in-in R28 Type1 696 - 1018 None None 0
8F1YA 2.75 Active DFGin BLAminus in-in in-in R2E Type1 696 - 1019 None None 3
8TJLA 2.7 Active DFGin BLAminus in-in in-in HZ6 Type1 696 - 1019 None None 2
8HV2A 2.8 Active DFGin BLAminus in-in in-in MWU Type1 697 - 1019 None None 5
1M17A 2.6 Active DFGin BLAminus in-in in-in AQ4 Type1 696 - 1019 None None 0
7B85A 2.5 Active DFGin BLAminus in-in in-in R28 Type1 697 - 1020 None None 2
3VJOA 2.64 Inactive DFGin BLAminus in-out in-in ANP Type1 696 - 1018 None None 0
7AEMA 2.65 Active DFGin BLAminus in-in in-in 6GY Type1 695 - 1018 None None 0
2ITNA 2.47 Active DFGin BLAminus in-in in-in ANP Type1 696 - 1019 G719S None 9
2ITOA 3.25 Active DFGin BLAminus in-in in-in IRE Type1 696 - 1019 G719S None 9
2ITPA 2.74 Active DFGin BLAminus in-in in-in AEE Type1 697 - 1018 G719S None 0
2ITQA 2.68 Active DFGin BLAminus in-in in-in ITQ Type1 697 - 1018 G719S None 0
6S9BA 3.25 Active DFGin BLAminus in-in in-in L1H Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 12
6S9CA 2.73 Active DFGin BLAminus in-in in-in L1K Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 12
6S9DA 2.67 Active DFGin BLAminus in-in in-in L3Z Type1 696 - 1017 T790M,L858R,E865A,E866A,K867A None 11
8HY7A 2.91 Inactive DFGin BLAminus in-out in-in NSO Type1 696 - 1019 E865A,E866A,K867A None 14
4RJ4A 2.78 Active DFGin BLAminus in-in in-in 3QW Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
4RJ7A 2.55 Active DFGin BLAminus in-in in-in 3R1 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
4RJ8A 2.5 Active DFGin BLAminus in-in in-in 3QS Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
5C8KA 3.0 Active DFGin BLAminus in-in in-in 4YV Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 15
5C8MA 2.9 Active DFGin BLAminus in-in in-in 4YW Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 14
5C8NA 2.401 Active DFGin BLAminus in-in in-in 4YX Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
5CALA 2.7 Active DFGin BLAminus in-in in-in 4Z8 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 15
5CANA 2.8 Active DFGin BLAminus in-in in-in 4ZB Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
5CAOA 2.6 None DFGin BLAminus in-in none-in 4ZG Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 16
5CAPA 2.4 Active DFGin BLAminus in-in in-in 4ZH Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 15
5EM7A 2.81 Active DFGin BLAminus in-in in-in 5Q4 Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
5HCXA 2.6 Active DFGin BLAminus in-in in-in 60B Type1 696 - 1018 T790M,L858R,E865A,E866A,K867A None 14
5HCZA 2.62 Active DFGin BLAminus in-in in-in 60E Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
5HIBA 2.85 Active DFGin BLAminus in-in in-in 63M Type1 696 - 1018 T790M,L858R,E865A,E866A,K867A None 5
6JRKA 2.796 Inactive DFGin BLAminus in-out in-in C6O Type1 696 - 1018 E865A,E866A,K867A None 15
2ITTA 2.73 Active DFGin BLAminus in-in in-in AEE Type1 697 - 1019 L858R None 9
2ITUA 2.8 Inactive DFGin BLAminus in-out in-in ITQ Type1 696 - 1019 L858R None 10
2ITVA 2.47 Active DFGin BLAminus in-in in-in ANP Type1 696 - 1019 L858R None 9
2ITZA 2.8 Inactive DFGin BLAminus in-out in-in IRE Type1 697 - 1020 L858R None 10
5X26A 2.951 Active DFGin BLAminus in-in in-in 7XO Type1 697 - 1020 L858R None 9
5X27A 2.952 Active DFGin BLAminus in-in in-in 7XR Type1 697 - 1020 L858R None 9
5X28A 2.952 Active DFGin BLAminus in-in in-in 7XU Type1 697 - 1020 L858R None 9
5XDLA 2.7 None DFGin BLAminus in-in in-none 8JC Type1 696 - 1018 L858R None 15
6JWLA 2.551 Active DFGin BLAminus in-in in-in YY3 Type1 696 - 1020 L858R None 6
4LQMA 2.5 Active DFGin BLAminus in-in in-in DJK Type1 697 - 1019 L858R None 7
7LGSA 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 702 - 984 V948R None 0
7LGSB 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 702 - 984 V948R None 0
7LGSC 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 701 - 984 V948R None 0
7LGSD 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 701 - 984 V948R None 0
7T4JA 2.2 Active DFGin BLAminus in-in in-in R28 Type1 701 - 984 V948R None 0
7T4JB 2.2 Active DFGin BLAminus in-in in-in R28 Type1 701 - 984 V948R None 0
4LRMA 3.526 Active DFGin BLAminus in-in in-in YUN Type1 696 - 999 None None 0
4LRMB 3.526 Active DFGin BLAminus in-in in-in YUN Type1 695 - 984 None None 0
4LRMC 3.526 Active DFGin BLAminus in-in in-in YUN Type1 694 - 983 None None 0
4LRMD 3.526 Active DFGin BLAminus in-in in-in YUN Type1 696 - 981 None None 0
4LRME 3.526 Active DFGin BLAminus in-in in-in YUN Type1 697 - 983 None None 0
6JX0A 2.53 Active DFGin BLAminus in-in in-in YY3 YY3 Type1 Allosteric 701 - 989 T790M None 0
4G5JA 2.8 Active DFGin BLAminus in-in in-in 0WN 0WM 0WM Type1 Allosteric Allosteric 696 - 1016 None None 0
8D73A 2.17 Active DFGin BLAminus in-in in-in QCR Type1.5_Back 703 - 1011 T790M,L858R,V948R None 0
8D73B 2.17 Active DFGin BLAminus in-in in-in QCR Type1.5_Back 704 - 1012 T790M,L858R,V948R None 0
8D76A 2.4 Active DFGin BLAminus in-in in-in QFO Type1.5_Back 703 - 1014 T790M,L858R,V948R None 0
8D76B 2.4 Active DFGin BLAminus in-in in-in QFO Type1.5_Back 702 - 1014 T790M,L858R,V948R None 0
6D8EA 2.537 Active DFGin BLAminus in-in in-in FZP Type1.5_Back 696 - 1019 None None 5
8F1ZA 2.4 Active DFGin BLAminus in-in in-in X9B Type1.5_Back 695 - 1018 None None 0
4RJ5A 3.1 None DFGin BLAminus in-in none-in 3QY Type1.5_Back 697 - 1019 T790M,L858R,E865A,E866A,K867A None 16
5CAQA 2.5 Active DFGin BLAminus in-in in-in 4ZJ Type1.5_Back 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
5CASA 2.1 Active DFGin BLAminus in-in in-in 4ZQ Type1.5_Back 696 - 1019 T790M,L858R,E865A,E866A,K867A None 13
5CAUA 2.25 Active DFGin BLAminus in-in in-in 4ZR Type1.5_Back 696 - 1018 T790M,L858R,E865A,E866A,K867A None 14
5HCYA 2.46 Active DFGin BLAminus in-in in-in 60D Type1.5_Back 696 - 1019 T790M,L858R,E865A,E866A,K867A None 13
5HICA 2.6 Active DFGin BLAminus in-in in-in 63N Type1.5_Back 697 - 1019 T790M,L858R,E865A,E866A,K867A None 14
4R5SA 3.001 Inactive DFGin BLAminus in-out in-in FI3 Type1.5_Back 697 - 1018 L858R None 9
3W2OA 2.35 Inactive DFGin BLAminus out-out in-in 03P Type1.5_Front 698 - 1017 T790M,L858R None 0
3W2PA 2.05 Inactive DFGin BLAminus out-out in-in W2P Type1.5_Front 698 - 1018 T790M,L858R None 0
3W2QA 2.2 Inactive DFGin BLAminus out-out in-in HKI Type1.5_Front 698 - 1017 T790M,L858R None 0
5EDPA 2.9 Inactive DFGin BLAplus in-in none-in No_ligand No_ligand 697 - 1018 T790M,L858R,E865A,E866A,K867A None 15
5XGMA 2.952 Inactive DFGin BLAplus in-in none-out 85X Type1 696 - 1019 T790M None 16
6JRJA 2.943 Inactive DFGin BLAplus in-out in-none C6O Type1 696 - 1018 T790M,C797S,E865A,E866A,K867A None 15
5Y25A 3.102 Inactive DFGin BLAplus in-in none-in 8LU Type1 698 - 1017 T790M,L858R None 16
5EDRA 2.6 Inactive DFGin BLAplus in-in none-in 5N4 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 16
5EM5A 2.65 Inactive DFGin BLAplus in-in none-in 5Q2 Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 16
2EB3A 2.84 Inactive DFGin BLAplus in-in in-in ANP Type1 696 - 1018 None None 14
6TFUB 2.0 Inactive DFGin BLAplus out-none none-out N7K Type1.5_Back 700 - 984 T790M,V948R None 16
5EDQA 2.8 Inactive DFGin BLAplus in-in none-in 5N3 Type1.5_Back 697 - 1018 T790M,L858R,E865A,E866A,K867A None 16
8A27A 1.07 Inactive DFGin BLAplus out-out none-out KY9 Type3 701 - 985 None None 16
8A2AA 1.43 Inactive DFGin BLAplus out-out out-out KY9 Type3 700 - 1019 None None 8
7JXIC 3.0 Inactive DFGin BLBminus out-out none-in 8BS Type1 700 - 1007 T790M,V948R None 18
4RJ6A 2.7 Inactive DFGin BLBminus in-in in-in 3R0 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
5EM6A 2.78 Inactive DFGin BLBminus in-in in-in 5Q3 Type1.5_Back 697 - 1019 T790M,L858R,E865A,E866A,K867A None 14
8A2DA 1.11 Inactive DFGin BLBminus out-out none-in KXY Type3 701 - 1021 L858R,V948R None 10
6WXNA 1.76 Inactive DFGin BLBplus out-out none-out No_ligand No_ligand 699 - 1014 T790M,V948R None 16
7UKWA 2.6 Inactive DFGin BLBplus out-out out-in No_ligand No_ligand 702 - 1014 T790M,V948R None 2
7TVDA 2.96 Inactive DFGin BLBplus in-out none-out No_ligand No_ligand 698 - 1009 None None 16
5ZTOA 2.649 Inactive DFGin BLBplus in-in none-none 9JO Type1 697 - 1017 T790M,C797S None 17
6P1LB 2.8 Inactive DFGin BLBplus out-out out-out ANP Type1 702 - 1008 T790M,V948R None 15
6V66D 1.79 Inactive DFGin BLBplus out-out out-in QP1 Type1 701 - 1014 T790M,V948R None 0
6V6KA 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 700 - 1014 T790M,V948R None 13
6V6KC 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 700 - 1014 T790M,V948R None 13
6V6KD 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 701 - 1014 T790M,V948R None 0
6V6KF 2.2 Inactive DFGin BLBplus out-out out-out QQJ Type1 701 - 1014 T790M,V948R None 8
6V6KG 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 701 - 1014 T790M,V948R None 0
6V6OC 2.1 Inactive DFGin BLBplus out-out out-out QQM Type1 701 - 1011 T790M,V948R None 12
6V6OD 2.1 Inactive DFGin BLBplus out-out out-in QQM Type1 701 - 1014 T790M,V948R None 0
6V6OE 2.1 Inactive DFGin BLBplus out-out out-in QQM Type1 701 - 1014 T790M,V948R None 11
6V6OH 2.1 Inactive DFGin BLBplus out-out out-in QQM Type1 700 - 1014 T790M,V948R None 11
6V5NA 2.4 Inactive DFGin BLBplus out-out out-in QP7 Type1 701 - 1014 T790M,V948R None 0
6V5PA 2.3 Inactive DFGin BLBplus out-out out-in QP4 Type1 701 - 1014 T790M,V948R None 0
6WAKA 2.4 Inactive DFGin BLBplus out-out out-in ANP Type1 702 - 1013 T790M,V948R None 10
6WAKD 2.4 Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 T790M,V948R None 14
8FV3A 2.1 Inactive DFGin BLBplus out-out out-in ANP Type1 701 - 1014 T790M,V948R None 12
8FV4C 2.2 Inactive DFGin BLBplus out-out out-out ANP Type1 702 - 1013 T790M,V948R None 11
4ZSED 1.97 Inactive DFGin BLBplus out-out out-in ANP Type1 701 - 1015 T790M,V948R None 12
5D41B 2.31 Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 T790M,V948R None 12
5X2AD 1.85 Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 T790M,V948R None 10
7JXKB 3.1 Inactive DFGin BLBplus out-out none-in ANP Type1 700 - 1007 T790M,V948R None 18
7JXLB 2.4 Inactive DFGin BLBplus out-out out-in VO7 Type1 700 - 1005 T790M,V948R None 15
7JXLC 2.4 Inactive DFGin BLBplus out-out out-out VO7 Type1 700 - 1007 T790M,V948R None 14
7JXLD 2.4 Inactive DFGin BLBplus out-out out-none VO7 Type1 700 - 1007 T790M,V948R None 16
7JXMC 2.192 Inactive DFGin BLBplus out-out out-in ANP Type1 702 - 1006 T790M,V948R None 15
7KY0A 3.1 Inactive DFGin BLBplus out-out out-in XA4 Type1 701 - 1007 T790M,V948R None 14
6TFYA 1.7 Inactive DFGin BLBplus out-out none-out N7Z Type1 699 - 982 T790M,V948R None 15
7A6JB 2.0 Inactive DFGin BLBplus out-out out-out R2E Type1 699 - 984 T790M,V948R None 15
7ZYQA 2.1 Inactive DFGin BLBplus out-none out-out V58 Type1 700 - 984 T790M,V948R None 15
5FEEA 2.7 Inactive DFGin BLBplus in-in in-in 5X4 Type1 697 - 1018 T790M None 5
5GTYA 3.14 Inactive DFGin BLBplus out-out out-in 816 Type1 700 - 1014 T790M None 11
5GTYC 3.14 Inactive DFGin BLBplus out-out out-none 816 Type1 700 - 1013 T790M None 15
5GTYF 3.14 Inactive DFGin BLBplus out-none out-out 816 Type1 700 - 1013 T790M None 13
5CNOB 1.55 Inactive DFGin BLBplus out-out out-out ANP Type1 698 - 1015 V948R None 12
5CNNA 1.9 Inactive DFGin BLBplus out-out out-in ANP Type1 699 - 1014 I706Q None 13
6P1DB 2.4 Inactive DFGin BLBplus out-out out-out ANP NQ1 Type1 Type3 702 - 1013 None None 12
6P1LA 2.8 Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3 701 - 1007 T790M,V948R None 17
6P1LC 2.8 Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3 702 - 1005 T790M,V948R None 17
6P1LD 2.8 Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3 702 - 1015 T790M,V948R None 17
6P8QA 1.9 Inactive DFGin BLBplus out-out out-in ANP O57 Type1 Type3 699 - 1019 T790M,V948R None 12
6P8QB 1.9 Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3 698 - 1007 T790M,V948R None 10
6P8QC 1.9 Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3 699 - 1014 T790M,V948R None 0
6P8QD 1.9 Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3 700 - 1007 T790M,V948R None 12
6XL4A 2.06 Inactive DFGin BLBplus out-out out-in Q6K NQ1 Type1 Type3 700 - 1007 T790M,V948R None 15
6XL4D 2.06 Inactive DFGin BLBplus out-out out-in ANP NQ1 Type1 Type3 700 - 1013 T790M,V948R None 11
5D41A 2.31 Inactive DFGin BLBplus out-out none-in ANP 57N Type1 Type3 698 - 1014 T790M,V948R None 17
6DUKA 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 701 - 1006 T790M,V948R None 0
6DUKB 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 699 - 1007 T790M,V948R None 13
6DUKC 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 699 - 1007 T790M,V948R None 14
6DUKD 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 701 - 1007 T790M,V948R None 0
6DUKE 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 698 - 1007 T790M,V948R None 12
6DUKF 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 701 - 1009 T790M,V948R None 11
7JXKA 3.1 Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3 700 - 1007 T790M,V948R None 15
7JXKC 3.1 Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3 701 - 1007 T790M,V948R None 15
7JXKD 3.1 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 14
7JXKE 3.1 Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3 700 - 1007 T790M,V948R None 16
7JXKF 3.1 Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3 700 - 1007 T790M,V948R None 16
7JXMB 2.192 Inactive DFGin BLBplus out-out none-in YY3 9LL Type1 Type3 701 - 1012 T790M,V948R None 16
7JXMD 2.192 Inactive DFGin BLBplus out-out none-in ANP 9LL Type1 Type3 700 - 1007 T790M,V948R None 17
7JXPA 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 0
7JXPB 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 0
7JXPD 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 14
7JXPF 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 14
7JXQB 1.83 Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3 701 - 1007 T790M,V948R None 10
7JXQD 1.83 Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3 700 - 1007 T790M,V948R None 10
7JXWA 2.5 Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 16
7JXWB 2.5 Inactive DFGin BLBplus out-out none-none YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 17
7JXWC 2.5 Inactive DFGin BLBplus out-out out-in YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 15
7JXWD 2.5 Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 17
7LTXA 2.3 Inactive DFGin BLBplus out-out none-out ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 16
7LTXB 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 15
7LTXC 2.3 Inactive DFGin BLBplus out-out none-in ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 16
7LTXD 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 15
8GB4A 2.59 Inactive DFGin BLBplus out-out none-out ANP YW5 Type1 Type3 700 - 1007 T790M,V948R None 16
8GB4B 2.59 Inactive DFGin BLBplus out-out none-none ANP YW5 Type1 Type3 700 - 1007 T790M,V948R None 18
8GB4C 2.59 Inactive DFGin BLBplus out-out none-out ANP YW5 Type1 Type3 700 - 1012 T790M,V948R None 16
8GB4D 2.59 Inactive DFGin BLBplus out-out none-none ANP YW5 Type1 Type3 700 - 1007 T790M,V948R None 17
6Z4BA 2.5 Inactive DFGin BLBplus out-none out-out Q6K 9LL Type1 Type3 700 - 982 T790M,V948R None 12
6Z4BB 2.5 Inactive DFGin BLBplus out-out none-out Q6K 9LL Type1 Type3 699 - 984 T790M,V948R None 18
6Z4DB 2.0 Inactive DFGin BLBplus out-none none-out 8BS 57N Type1 Type3 700 - 984 T790M,V948R None 15
7K1IA 3.202 Inactive DFGin BLBplus out-out none-in ANP VNS Type1 Type3 700 - 1007 L858R,V948R None 17
5GNKA 1.796 Inactive DFGin BLBplus out-out out-out 80U Type1.5_Back 697 - 985 T790M None 12
6WA2A 2.4 Inactive DFGin BLBplus out-out out-out TOV Type1.5_Back 699 - 1014 T790M,V948R None 12
6WA2B 2.4 Inactive DFGin BLBplus out-out out-in TOV Type1.5_Back 701 - 1014 T790M,V948R None 0
6WA2C 2.4 Inactive DFGin BLBplus out-out out-in TOV Type1.5_Back 701 - 1014 T790M,V948R None 12
6WA2D 2.4 Inactive DFGin BLBplus out-out out-in TOV Type1.5_Back 701 - 1014 T790M,V948R None 0
8FV3C 2.1 Inactive DFGin BLBplus out-out none-out YA6 Type1.5_Back 701 - 1009 T790M,V948R None 17
8FV4D 2.2 Inactive DFGin BLBplus out-out out-in YAA Type1.5_Back 701 - 1005 T790M,V948R None 13
6TFUA 2.0 Inactive DFGin BLBplus out-out out-in N7K Type1.5_Back 700 - 982 T790M,V948R None 14
6TFVA 1.5 Inactive DFGin BLBplus out-none none-in N7Q Type1.5_Back 700 - 985 T790M,V948R None 16
6TFVB 1.5 Inactive DFGin BLBplus out-out none-in N7Q Type1.5_Back 698 - 984 T790M,V948R None 16
6TFWA 2.0 Inactive DFGin BLBplus out-out out-in N7W Type1.5_Back 700 - 982 T790M,V948R None 14
6TFWB 2.0 Inactive DFGin BLBplus out-out none-out N7W Type1.5_Back 700 - 984 T790M,V948R None 18
6TFYB 1.7 Inactive DFGin BLBplus out-out none-out N7Z Type1.5_Back 699 - 984 T790M,V948R None 17
6TFZA 1.8 Inactive DFGin BLBplus out-none none-in N7B Type1.5_Back 701 - 982 T790M,V948R None 16
6TFZB 1.8 Inactive DFGin BLBplus out-none out-in N7B Type1.5_Back 700 - 984 T790M,V948R None 14
6TG0A 1.5 Inactive DFGin BLBplus out-out none-in N78 Type1.5_Back 700 - 985 T790M,V948R None 18
6TG0B 1.5 Inactive DFGin BLBplus out-out out-in N78 Type1.5_Back 698 - 984 T790M,V948R None 11
6TG1A 1.6 Inactive DFGin BLBplus out-out none-out N82 Type1.5_Back 699 - 984 T790M,V948R None 18
6TG1B 1.6 Inactive DFGin BLBplus out-none none-out N82 Type1.5_Back 698 - 984 T790M,V948R None 16
2JIVB 3.5 Inactive DFGin BLBplus out-out out-out HKI Type1.5_Back 699 - 982 T790M None 11
5GTYB 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 700 - 1014 T790M None 12
5GTYD 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 701 - 1014 T790M None 12
5GTYE 3.14 Inactive DFGin BLBplus out-none out-out 816 Type1.5_Back 701 - 1014 T790M None 12
5GTYG 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 699 - 1014 T790M None 12
5GTYH 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 700 - 1016 T790M None 12
3W2RA 2.05 Inactive DFGin BLBplus out-out out-in W2R Type1.5_Back 698 - 1017 T790M,L858R None 14
2RGPA 2.0 Inactive DFGin BLBplus out-out out-in HYZ Type1.5_Back 702 - 1016 None None 8
3BELA 2.3 Inactive DFGin BLBplus out-out out-in POX Type1.5_Back 702 - 1015 None None 8
3LZBA 2.7 Inactive DFGin BLBplus out-out none-out ITI Type1.5_Back 703 - 983 V948R None 16
3LZBB 2.7 Inactive DFGin BLBplus out-out none-in ITI Type1.5_Back 703 - 983 V948R None 16
3LZBC 2.7 Inactive DFGin BLBplus out-out none-in ITI Type1.5_Back 704 - 983 V948R None 16
3LZBD 2.7 Inactive DFGin BLBplus out-out none-in ITI Type1.5_Back 703 - 983 V948R None 16
3POZA 1.5 Inactive DFGin BLBplus out-out out-in 03P Type1.5_Back 701 - 1017 None None 7
3W2SA 1.9 Inactive DFGin BLBplus out-out out-out W2R Type1.5_Back 701 - 1019 None None 12
3W32A 1.8 Inactive DFGin BLBplus out-out out-in W32 Type1.5_Back 701 - 1017 None None 0
3W33A 1.7 Inactive DFGin BLBplus out-out out-in W19 Type1.5_Back 701 - 1018 None None 12
1XKKA 2.4 Inactive DFGin BLBplus out-out out-out FMM Type1.5_Back 702 - 1018 None None 8
6WAKC 2.4 Inactive DFGin BLBplus out-out none-out TQA Type1.5_Front 701 - 1014 T790M,V948R None 15
6WXNC 1.76 Inactive DFGin BLBplus out-out none-out UEJ Type1.5_Front 701 - 1014 T790M,V948R None 16
6WXND 1.76 Inactive DFGin BLBplus out-out out-in UEJ Type1.5_Front 702 - 1014 T790M,V948R None 13
7LG8B 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type1.5_Front Type1 702 - 1002 T790M,V948R None 15
5ZWJA 2.9 Inactive DFGin BLBplus out-none none-out 9LL Type3 702 - 985 T790M,C797S,V948R None 17
8A2BA 1.69 Inactive DFGin BLBplus out-out none-out KY9 Type3 702 - 990 L858R,V948R None 17
6P1DC 2.4 Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1 702 - 1006 None None 13
6P1DD 2.4 Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1 701 - 1008 None None 13
6XL4B 2.06 Inactive DFGin BLBplus out-out none-in NQ1 Q6K Type3 Type1 700 - 1007 T790M,V948R None 16
7JXPC 2.16 Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1 700 - 1007 T790M,V948R None 16
7JXPE 2.16 Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1 700 - 1007 T790M,V948R None 16
7JXQA 1.83 Inactive DFGin BLBplus out-out out-out VNS ANP Type3 Type1 700 - 1007 T790M,V948R None 12
7JXQC 1.83 Inactive DFGin BLBplus out-out out-in VNS ANP Type3 Type1 700 - 1007 T790M,V948R None 10
7LG8A 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1 702 - 1006 T790M,V948R None 15
7LG8C 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1 703 - 1004 T790M,V948R None 15
7LG8D 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type3 Type1 702 - 1003 T790M,V948R None 17
7A2AA 1.9 Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1 700 - 984 T790M,V948R None 17
7A2AB 1.9 Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1 699 - 984 T790M,V948R None 18
7K1HA 2.602 Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 16
7K1HB 2.602 Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1 701 - 1008 L858R,V948R None 17
7K1HC 2.602 Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 17
7K1HD 2.602 Inactive DFGin BLBplus out-out out-out VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 15
7K1HE 2.602 Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1 703 - 1007 L858R,V948R None 16
7K1HF 2.602 Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 17
6XL4C 2.06 Inactive DFGin BLBtrans out-out out-in No_ligand No_ligand 700 - 1011 T790M,V948R None 7
7UKWD 2.6 Inactive DFGin BLBtrans out-out out-in No_ligand No_ligand 702 - 1012 T790M,V948R None 6
8FV4B 2.2 Inactive DFGin BLBtrans out-out out-in No_ligand No_ligand 702 - 1007 T790M,V948R None 3
2RFDA 3.6 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 K823E None 11
2RFDB 3.6 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 K823E None 8
2RFEA 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 702 - 1002 K823E None 8
2RFEB 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1012 K823E None 11
2RFEC 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 702 - 983 K823E None 11
2RFED 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 K823E None 11
6P1DA 2.4 Inactive DFGin BLBtrans out-out out-in ANP Type1 700 - 1021 None None 13
6V66A 1.79 Inactive DFGin BLBtrans out-out out-in QP1 Type1 701 - 1014 T790M,V948R None 0
6V66B 1.79 Inactive DFGin BLBtrans out-out out-out QP1 Type1 701 - 1014 T790M,V948R None 12
6V66C 1.79 Inactive DFGin BLBtrans out-out out-in QP1 Type1 701 - 1012 T790M,V948R None 13
6V6KB 2.2 Inactive DFGin BLBtrans out-out out-none QQJ Type1 700 - 1014 T790M,V948R None 14
6V6KE 2.2 Inactive DFGin BLBtrans out-out out-in QQJ Type1 701 - 1014 T790M,V948R None 11
6V6KH 2.2 Inactive DFGin BLBtrans out-out out-out QQJ Type1 701 - 1014 T790M,V948R None 0
6V6OA 2.1 Inactive DFGin BLBtrans out-out out-in QQM Type1 701 - 1007 T790M,V948R None 0
6V6OB 2.1 Inactive DFGin BLBtrans out-out out-out QQM Type1 701 - 1014 T790M,V948R None 0
6V6OF 2.1 Inactive DFGin BLBtrans out-out out-in QQM Type1 701 - 1012 T790M,V948R None 13
6V6OG 2.1 Inactive DFGin BLBtrans out-out out-in QQM Type1 701 - 1009 T790M,V948R None 15
6V5NB 2.4 Inactive DFGin BLBtrans out-out out-in QP7 Type1 700 - 1008 T790M,V948R None 12
6V5NC 2.4 Inactive DFGin BLBtrans out-out out-out QP7 Type1 701 - 1007 T790M,V948R None 13
6V5ND 2.4 Inactive DFGin BLBtrans out-out out-in QP7 Type1 701 - 1008 T790M,V948R None 0
6V5PB 2.3 Inactive DFGin BLBtrans out-out out-out QP4 Type1 701 - 1012 T790M,V948R None 13
6V5PC 2.3 Inactive DFGin BLBtrans out-out out-in QP4 Type1 701 - 1008 T790M,V948R None 13
6V5PD 2.3 Inactive DFGin BLBtrans out-out out-in QP4 Type1 701 - 1008 T790M,V948R None 0
6WAKB 2.4 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1020 T790M,V948R None 4
6WXNB 1.76 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1021 T790M,V948R None 11
7UKWB 2.6 Inactive DFGin BLBtrans out-out none-in ZRT Type1 702 - 1010 T790M,V948R None 17
7UKWC 2.6 Inactive DFGin BLBtrans out-out out-in ZRT Type1 700 - 1005 T790M,V948R None 13
8FV3B 2.1 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1021 T790M,V948R None 12
8FV3D 2.1 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1008 T790M,V948R None 12
8FV4A 2.2 Inactive DFGin BLBtrans out-out out-out ANP Type1 701 - 1013 T790M,V948R None 13
4ZSEA 1.97 Inactive DFGin BLBtrans out-out out-in ANP Type1 699 - 1007 T790M,V948R None 12
4ZSEB 1.97 Inactive DFGin BLBtrans out-out out-in ANP Type1 698 - 1022 T790M,V948R None 12
4ZSEC 1.97 Inactive DFGin BLBtrans out-out out-in ANP Type1 700 - 1013 T790M,V948R None 13
5X2AC 1.85 Inactive DFGin BLBtrans out-out out-out 7XO Type1 700 - 1015 T790M,V948R None 13
5X2CA 2.05 Inactive DFGin BLBtrans out-out out-out 7XR Type1 700 - 1015 T790M,V948R None 12
5X2CB 2.05 Inactive DFGin BLBtrans out-out out-out 7XR Type1 701 - 1014 T790M,V948R None 11
5X2FA 2.2 Inactive DFGin BLBtrans out-out out-out 7XU Type1 700 - 1014 T790M,V948R None 12
5X2FB 2.2 Inactive DFGin BLBtrans out-out out-in 7XU Type1 699 - 1010 T790M,V948R None 0
5X2FC 2.2 Inactive DFGin BLBtrans out-out out-in 7XU Type1 700 - 1014 T790M,V948R None 13
5X2FD 2.2 Inactive DFGin BLBtrans out-out out-out 7XU Type1 697 - 1014 T790M,V948R None 7
7JXIA 3.0 Inactive DFGin BLBtrans out-out none-in 8BS Type1 700 - 1006 T790M,V948R None 17
7JXID 3.0 Inactive DFGin BLBtrans out-out out-in 8BS Type1 702 - 1006 T790M,V948R None 13
7JXLA 2.4 Inactive DFGin BLBtrans out-out out-in VO7 Type1 701 - 1013 T790M,V948R None 14
7JXMA 2.192 Inactive DFGin BLBtrans out-out out-in ANP Type1 700 - 1007 T790M,V948R None 14
7KY0B 3.1 Inactive DFGin BLBtrans out-out out-out XA4 Type1 700 - 1007 T790M,V948R None 14
7KY0D 3.1 Inactive DFGin BLBtrans out-out out-in XA4 Type1 700 - 1007 T790M,V948R None 14
7U98B 3.42 Inactive DFGin BLBtrans out-out out-out M1O Type1 701 - 1005 T790M,V948R None 12
7U98C 3.42 Inactive DFGin BLBtrans out-out out-out M1O Type1 702 - 1007 T790M,V948R None 14
7U98D 3.42 Inactive DFGin BLBtrans out-out none-out M1O Type1 701 - 1007 T790M,V948R None 16
8F1WA 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 701 - 1007 T790M,V948R None 4
8F1WB 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 700 - 1007 T790M,V948R None 14
8F1WC 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 700 - 1007 T790M,V948R None 14
8F1WD 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 700 - 1007 T790M,V948R None 4
6Z4DA 2.0 Inactive DFGin BLBtrans out-out out-out 8BS Type1 701 - 984 T790M,V948R None 13
7A6JA 2.0 Inactive DFGin BLBtrans out-out out-out R2E Type1 699 - 982 T790M,V948R None 14
7A6KA 2.0 Inactive DFGin BLBtrans out-out out-out R28 Type1 700 - 984 T790M,V948R None 14
7A6KB 2.0 Inactive DFGin BLBtrans out-none none-out R28 Type1 700 - 982 T790M,V948R None 17
7A6KC 2.0 Inactive DFGin BLBtrans out-none none-out R28 Type1 700 - 984 T790M,V948R None 17
7A6KD 2.0 Inactive DFGin BLBtrans out-out none-out R28 Type1 702 - 984 T790M,V948R None 18
4I24A 1.8 Inactive DFGin BLBtrans out-out out-out 1C9 Type1 700 - 1014 T790M None 13
4I24B 1.8 Inactive DFGin BLBtrans out-out out-in 1C9 Type1 700 - 1014 T790M None 11
5YU9A 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 700 - 1017 T790M None 12
5YU9B 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 699 - 1011 T790M None 13
5YU9C 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 697 - 1021 T790M None 12
5YU9D 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 700 - 1012 T790M None 13
4I22A 1.71 Inactive DFGin BLBtrans out-out out-out IRE Type1 700 - 1014 T790M,L858R,V948R None 13
2GS7A 2.6 Inactive DFGin BLBtrans out-out out-out ANP Type1 703 - 1012 V948R None 4
2GS7B 2.6 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1016 V948R None 3
3GT8A 2.955 Inactive DFGin BLBtrans out-out out-none ANP Type1 700 - 1014 V948R None 15
3GT8B 2.955 Inactive DFGin BLBtrans out-out out-none ANP Type1 701 - 1007 V948R None 15
3GT8C 2.955 Inactive DFGin BLBtrans out-out out-in ANP Type1 699 - 1007 V948R None 13
3GT8D 2.955 Inactive DFGin BLBtrans out-out out-none ANP Type1 701 - 1010 V948R None 15
5CNOA 1.55 Inactive DFGin BLBtrans out-out out-out ANP Type1 700 - 1015 V948R None 11
4HJOA 2.75 Inactive DFGin BLBtrans out-out out-out AQ4 Type1 703 - 984 V948R None 0
5CNNB 1.9 Inactive DFGin BLBtrans out-out out-out ANP Type1 700 - 1014 I706Q None 11
6JXTA 2.307 Inactive DFGin BLBtrans out-out out-in YY3 Type1 697 - 984 E865A,E866A,K867A None 2
5X2AA 1.85 Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Allosteric 700 - 1011 T790M,V948R None 13
5X2AB 1.85 Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Type1 700 - 1022 T790M,V948R None 0
8EMEA 3.32 Inactive DFGin None out-out none-none No_ligand No_ligand 700 - 1007 T790M,V948R None 21
3GOPA 2.8 Inactive DFGin None in-none none-in No_ligand No_ligand 676 - 1018 K745M None 18
7JXIB 3.0 Inactive DFGin None out-out none-in 8BS Type1 702 - 1004 T790M,V948R None 17
7KY0C 3.1 Inactive DFGin None out-out out-in XA4 Type1 700 - 1007 T790M,V948R None 14
7U98A 3.42 Inactive DFGin None out-out out-none M1O Type1 701 - 1007 T790M,V948R None 14
7ZYQB 2.1 Inactive DFGin None out-out none-out V58 Type1 700 - 984 T790M,V948R None 19
4RIWB 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 4
4RIWD 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 0
4RIXB 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 4
4RIXD 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 0
4RIYB 2.981 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 4
4RIYD 2.981 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 0
2JIVA 3.5 Inactive DFGin None out-out out-in HKI Type1.5_Back 700 - 984 T790M None 14
8H7XB 3.404 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1018 T790M,C797S None 7
5XGNB 3.0 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1019 T790M,C797S None 4
2JITB 3.1 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1018 T790M None 0
2JIUB 3.05 Inactive DFGinter None in-in in-in No_ligand No_ligand 695 - 1004 T790M None 0
4G5PB 3.17 Inactive DFGinter None in-in out-out No_ligand No_ligand 697 - 1018 T790M None 8
3IKAB 2.9 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1017 T790M None 2
4WD5B 3.3 Inactive DFGinter None in-out out-out No_ligand No_ligand 697 - 1016 T790M None 5
5UWDA 3.06 Inactive DFGinter None out-out out-out 8OV Type1 702 - 984 T790M,L858R,V948R None 12
2RF9A 3.5 Inactive DFGout BBAminus out-none in-in No_ligand No_ligand 699 - 983 None None 2
4ZJVA 2.7 Inactive DFGout BBAminus out-out in-in No_ligand No_ligand 703 - 985 None None 0
4ZJVB 2.7 Inactive DFGout BBAminus out-out in-in No_ligand No_ligand 703 - 982 None None 0
5HG5A 1.52 Inactive DFGout BBAminus out-out in-in 633 Type1 700 - 1001 T790M,L858R,V948R None 0
5HG7A 1.85 Inactive DFGout BBAminus out-out in-in 630 Type1 702 - 984 T790M,L858R,V948R None 0
5HG8A 1.42 Inactive DFGout BBAminus out-out in-in 634 Type1 700 - 999 T790M,L858R,V948R None 0
5HG9A 2.15 Inactive DFGout BBAminus out-out in-in 63A Type1 702 - 985 T790M,L858R,V948R None 0
5U8LA 1.6 Inactive DFGout BBAminus out-out in-in O44 Type1 702 - 990 None None 0
5UG8A 1.46 Inactive DFGout BBAminus out-out in-in 8BP Type1 702 - 985 T790M,L858R,V948R None 0
5UG9A 1.33 Inactive DFGout BBAminus out-out in-in 8AM Type1 702 - 985 T790M,L858R,V948R None 0
5UGAA 1.82 Inactive DFGout BBAminus out-out in-in 8BM Type1 703 - 985 T790M,L858R,V948R None 0
5UGCA 1.58 Inactive DFGout BBAminus out-out in-in 8BS Type1 702 - 985 T790M,L858R,V948R None 0
4I1ZA 3.0 Inactive DFGout None out-out in-in No_ligand No_ligand 701 - 987 T790M,L858R,V948R None 0
4I21A 3.37 Inactive DFGout None out-out in-in No_ligand No_ligand 703 - 1019 T790M,L858R None 0
4I21B 3.37 Inactive DFGout None out-out in-in No_ligand No_ligand 703 - 1020 T790M,L858R None 0
2RF9B 3.5 Inactive DFGout None out-none in-out No_ligand No_ligand 701 - 985 None None 6
4I20A 3.34 Inactive DFGout None out-out in-in No_ligand No_ligand 701 - 987 L858R,V948R None 0
8DSWA 2.39 Inactive None None none-none in-in ANP Type1 696 - 1017 None None 9

EGFR (Epidermal growth factor receptor)

Group: TYR
Total number of chains: 439
Spatial Dihedral Chains Representative
DFGin BLAminus 154 AF-P00533-K1A
DFGin BLAplus 11 8A2AA
DFGin ABAminus 4 3IKAA
DFGin BLBminus 4 8A2DA
DFGin BLBplus 146 6V66D
DFGin BLBtrans 81 6V66A
DFGin None 13 4RIYD
DFGinter None 8 2JIUB
DFGout BBAminus 12 5HG8A
DFGout None 5 4I1ZA
None None 1 8DSWA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens EGFR_HUMAN 3IKAA 2.9 Inactive DFGin ABAminus in-in in-in 0UN Type1 696 - 1020 T790M None 0
Homo sapiens EGFR_HUMAN 7ER2A 2.662 Inactive DFGin ABAminus in-in in-in JAU Type1 697 - 1018 T790M,C797S None 7
Homo sapiens EGFR_HUMAN 4LL0A 4.0 Inactive DFGin ABAminus in-out in-in YUN Type1 697 - 1017 T790M,L858R None 13
Homo sapiens EGFR_HUMAN 4LL0B 4.0 Inactive DFGin ABAminus in-out in-in YUN Type1 698 - 1017 T790M,L858R None 14
Homo sapiens EGFR_HUMAN 8HV4A 2.2 Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1 696 - 1020 E865A,E866A,K867A None 3
Homo sapiens EGFR_HUMAN 8HV6A 2.2 Active DFGin BLAminus in-in in-in PE5 N86 Allosteric Type1 696 - 1020 E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 8HV7A 2.69 Active DFGin BLAminus in-in in-in PE5 N8O Allosteric Type1 696 - 1019 E865A,E866A,K867A None 6
Homo sapiens EGFR_HUMAN 8HV8A 2.4 Active DFGin BLAminus in-in in-in PE5 N99 Allosteric Type1 696 - 1019 C797S,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 8HV9A 2.5 Active DFGin BLAminus in-in in-in PE5 N9L Allosteric Type1 696 - 1019 E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 8HV1A 2.4 Active DFGin BLAminus in-in in-in PE5 N6N Allosteric Type1 696 - 1019 E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 8HV3A 2.4 Active DFGin BLAminus in-in in-in PE5 MWU Allosteric Type1 696 - 1020 E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 8HV5A 2.2 Active DFGin BLAminus in-in in-in PE5 N7C Allosteric Type1 696 - 1019 E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 2JITA 3.1 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1016 T790M None 0
Homo sapiens EGFR_HUMAN 3UG1A 2.75 Active DFGin BLAminus in-in in-in No_ligand No_ligand 697 - 1018 G719S,T790M None 0
Homo sapiens EGFR_HUMAN AF-P00533-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 704 - 978 None None 0
Homo sapiens EGFR_HUMAN 2J5EA 3.1 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1020 None None 0
Homo sapiens EGFR_HUMAN 2GS2A 2.8 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1018 None None 0
Homo sapiens EGFR_HUMAN 2GS6A 2.6 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 4WRGA 1.9 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1019 None None 2
Homo sapiens EGFR_HUMAN 7SI1A 1.6 Active DFGin BLAminus in-in in-in No_ligand No_ligand 695 - 1020 None None 0
Homo sapiens EGFR_HUMAN 4TKSA 3.202 Active DFGin BLAminus in-in in-in No_ligand No_ligand 697 - 1019 None None 0
Homo sapiens EGFR_HUMAN 1M14A 2.6 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1020 None None 0
Homo sapiens EGFR_HUMAN 2EB2A 2.5 Active DFGin BLAminus in-in in-in No_ligand No_ligand 696 - 1019 None None 1
Homo sapiens EGFR_HUMAN 4R3PA 2.905 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
Homo sapiens EGFR_HUMAN 4R3RA 3.25 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
Homo sapiens EGFR_HUMAN 5CZHA 2.8 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
Homo sapiens EGFR_HUMAN 5CZIA 2.6 Inactive DFGin BLAminus out-out in-in No_ligand No_ligand 696 - 1018 L858R None 0
Homo sapiens EGFR_HUMAN 8H7XA 3.404 Active DFGin BLAminus in-in in-in 6GY Type1 697 - 1019 T790M,C797S None 0
Homo sapiens EGFR_HUMAN 5XGNA 3.0 Active DFGin BLAminus in-in in-in 85X Type1 697 - 1020 T790M,C797S None 0
Homo sapiens EGFR_HUMAN 6JRXA 2.201 Active DFGin BLAminus in-in in-in 9JO Type1 696 - 1017 T790M,C797S None 3
Homo sapiens EGFR_HUMAN 5J9YA 2.8 Active DFGin BLAminus in-in in-in 6HL Type1 697 - 1019 None None 3
Homo sapiens EGFR_HUMAN 8EMEB 3.32 None DFGin BLAminus out-out none-none ZNL Type1 702 - 1007 T790M,V948R None 19
Homo sapiens EGFR_HUMAN 5J9ZA 2.5 Active DFGin BLAminus in-in in-in 6HJ Type1 696 - 1020 T790M None 15
Homo sapiens EGFR_HUMAN 7A6IA 2.4 Inactive DFGin BLAminus out-out in-in R1W Type1 703 - 984 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 5X2KA 3.201 Active DFGin BLAminus in-in in-in 0UN Type1 696 - 1020 T790M None 6
Homo sapiens EGFR_HUMAN 2JIUA 3.05 Inactive DFGin BLAminus in-out in-in AEE Type1 696 - 1016 T790M None 0
Homo sapiens EGFR_HUMAN 5FEQA 3.4 Active DFGin BLAminus in-in in-in 5XH Type1 697 - 1017 T790M None 5
Homo sapiens EGFR_HUMAN 4G5PA 3.17 Active DFGin BLAminus in-in in-in 0WN Type1 696 - 1016 T790M None 0
Homo sapiens EGFR_HUMAN 5GMPA 2.797 Inactive DFGin BLAminus in-in in-out F62 Type1 696 - 1019 T790M None 11
Homo sapiens EGFR_HUMAN 5GTZA 2.999 Active DFGin BLAminus in-in in-in 81C Type1 697 - 1020 T790M None 7
Homo sapiens EGFR_HUMAN 5XDKA 2.346 Active DFGin BLAminus in-in in-in 8JC Type1 696 - 1018 T790M None 0
Homo sapiens EGFR_HUMAN 6JX4A 2.531 Active DFGin BLAminus in-in in-in YY3 Type1 696 - 1018 T790M None 8
Homo sapiens EGFR_HUMAN 4WD5A 3.3 Inactive DFGin BLAminus out-out in-out 3LH Type1 694 - 1021 T790M None 0
Homo sapiens EGFR_HUMAN 5Y9TA 3.25 Active DFGin BLAminus in-in in-in 8RC Type1 697 - 1020 T790M None 0
Homo sapiens EGFR_HUMAN 3UG2A 2.5 Inactive DFGin BLAminus in-out in-in IRE Type1 697 - 1018 G719S,T790M None 0
Homo sapiens EGFR_HUMAN 3VJNA 2.34 Inactive DFGin BLAminus in-out in-in ANP Type1 697 - 1018 G719S,T790M None 0
Homo sapiens EGFR_HUMAN 7VRAA 2.41 Active DFGin BLAminus in-in in-in I0A Type1 696 - 1018 T790M,C797S None 11
Homo sapiens EGFR_HUMAN 7VREA 2.507 Active DFGin BLAminus in-in in-in 7VH Type1 696 - 1018 T790M,C797S None 8
Homo sapiens EGFR_HUMAN 6S89A 2.701 Active DFGin BLAminus in-in in-in L0Q Type1 697 - 1017 T790M,C797S,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 6S8AA 2.6 Active DFGin BLAminus in-in in-in L0N Type1 697 - 1018 T790M,C797S,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 7ZYMA 2.5 Active DFGin BLAminus in-in in-in 6GY Type1 696 - 1020 T790M,C797S,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 7ZYNA 2.3 Active DFGin BLAminus in-in in-in 0UN Type1 697 - 1018 T790M,C797S,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 7ZYPA 2.8 None DFGin BLAminus in-none in-in R25 Type1 695 - 1019 T790M,C797S,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 7OXBA 2.56 Active DFGin BLAminus in-in in-in 35Z Type1 696 - 1019 None None 6
Homo sapiens EGFR_HUMAN 8WD4A 2.55 Active DFGin BLAminus in-in in-in W7W Type1 696 - 1019 T790M,C797S,L858R None 11
Homo sapiens EGFR_HUMAN 6LUBA 2.315 Active DFGin BLAminus in-in in-in EUX Type1 696 - 1018 T790M,C797S,L858R,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 6LUDA 2.05 Active DFGin BLAminus in-in in-in YY3 Type1 696 - 1018 T790M,C797S,L858R,E865A,E866A,K867A None 0
Homo sapiens EGFR_HUMAN 8HVAA 2.77 Active DFGin BLAminus in-in in-in N9R Type1 696 - 1020 E865A,E866A,K867A None 4
Homo sapiens EGFR_HUMAN 6JZ0A 2.86 Active DFGin BLAminus in-in in-in CKO Type1 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 2ITWA 2.88 Inactive DFGin BLAminus in-out in-in ITQ Type1 696 - 1018 None None 0
Homo sapiens EGFR_HUMAN 2ITXA 2.98 Active DFGin BLAminus in-in in-in ANP Type1 697 - 1019 None None 4
Homo sapiens EGFR_HUMAN 2ITYA 3.42 Active DFGin BLAminus in-in in-in IRE Type1 697 - 1019 None None 10
Homo sapiens EGFR_HUMAN 2J5FA 3.0 Active DFGin BLAminus in-in in-in DJK Type1 696 - 1020 None None 8
Homo sapiens EGFR_HUMAN 2J6MA 3.1 Active DFGin BLAminus in-in in-in AEE Type1 697 - 1020 None None 0
Homo sapiens EGFR_HUMAN 6VH4A 2.8 Active DFGin BLAminus in-in in-in QQM Type1 696 - 1019 None None 3
Homo sapiens EGFR_HUMAN 6VHNA 2.4 Active DFGin BLAminus in-in in-in QQJ Type1 696 - 1019 None None 13
Homo sapiens EGFR_HUMAN 6VHPA 3.6 Active DFGin BLAminus in-in in-in QP1 Type1 696 - 1019 None None 5
Homo sapiens EGFR_HUMAN 8G63A 2.5 Active DFGin BLAminus in-in in-in YXT Type1 696 - 1017 None None 14
Homo sapiens EGFR_HUMAN 7UKVA 2.4 Active DFGin BLAminus in-in in-in ZRT Type1 696 - 1018 None None 6
Homo sapiens EGFR_HUMAN 5FEDA 2.651 Active DFGin BLAminus in-in in-in 5X4 Type1 697 - 1017 None None 4
Homo sapiens EGFR_HUMAN 7T4IA 2.61 Active DFGin BLAminus in-in in-in R28 Type1 697 - 1017 None None 0
Homo sapiens EGFR_HUMAN 4JQ7A 2.73 Active DFGin BLAminus in-in in-in KJQ Type1 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 4JQ8A 2.83 Active DFGin BLAminus in-in in-in KJ8 Type1 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 4JR3A 2.7 Active DFGin BLAminus in-in in-in KJR Type1 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 4JRVA 2.8 Active DFGin BLAminus in-in in-in KJV Type1 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 4LI5A 2.64 Active DFGin BLAminus in-in in-in 1WY Type1 696 - 1020 None None 0
Homo sapiens EGFR_HUMAN 4I23A 2.8 Active DFGin BLAminus in-in in-in 1C9 Type1 695 - 1018 None None 0
Homo sapiens EGFR_HUMAN 5UGBA 2.53 Active DFGin BLAminus in-in in-in 8BM Type1 695 - 1018 None None 0
Homo sapiens EGFR_HUMAN 7AEIA 2.65 Active DFGin BLAminus in-in in-in R85 Type1 697 - 1018 None None 0
Homo sapiens EGFR_HUMAN 5JEBA 3.298 Active DFGin BLAminus in-in in-in 6JS Type1 699 - 999 V948R None 0
Homo sapiens EGFR_HUMAN 4WKQA 1.85 Active DFGin BLAminus in-in in-in IRE Type1 696 - 1020 None None 0
Homo sapiens EGFR_HUMAN 4ZAUA 2.8 Active DFGin BLAminus in-in in-in YY3 Type1 698 - 1017 None None 5
Homo sapiens EGFR_HUMAN 5CAVA 2.73 Active DFGin BLAminus in-in in-in 4ZQ Type1 697 - 1020 None None 0
Homo sapiens EGFR_HUMAN 5EM8A 2.8 Active DFGin BLAminus in-in in-in 5Q4 Type1 696 - 1018 None None 2
Homo sapiens EGFR_HUMAN 7KXZA 2.4 Active DFGin BLAminus in-in in-in XA4 Type1 696 - 1017 None None 0
Homo sapiens EGFR_HUMAN 7U99A 2.5 Active DFGin BLAminus in-in in-in M0R Type1 695 - 1018 None None 0
Homo sapiens EGFR_HUMAN 7U9AA 2.6 Active DFGin BLAminus in-in in-in M19 Type1 695 - 1018 None None 4
Homo sapiens EGFR_HUMAN 8F1HA 2.8 Active DFGin BLAminus in-in in-in X9H Type1 697 - 1018 None None 0
Homo sapiens EGFR_HUMAN 8F1XA 2.3 Active DFGin BLAminus in-in in-in R28 Type1 696 - 1018 None None 0
Homo sapiens EGFR_HUMAN 8F1YA 2.75 Active DFGin BLAminus in-in in-in R2E Type1 696 - 1019 None None 3
Homo sapiens EGFR_HUMAN 8TJLA 2.7 Active DFGin BLAminus in-in in-in HZ6 Type1 696 - 1019 None None 2
Homo sapiens EGFR_HUMAN 8HV2A 2.8 Active DFGin BLAminus in-in in-in MWU Type1 697 - 1019 None None 5
Homo sapiens EGFR_HUMAN 1M17A 2.6 Active DFGin BLAminus in-in in-in AQ4 Type1 696 - 1019 None None 0
Homo sapiens EGFR_HUMAN 7B85A 2.5 Active DFGin BLAminus in-in in-in R28 Type1 697 - 1020 None None 2
Homo sapiens EGFR_HUMAN 3VJOA 2.64 Inactive DFGin BLAminus in-out in-in ANP Type1 696 - 1018 None None 0
Homo sapiens EGFR_HUMAN 7AEMA 2.65 Active DFGin BLAminus in-in in-in 6GY Type1 695 - 1018 None None 0
Homo sapiens EGFR_HUMAN 2ITNA 2.47 Active DFGin BLAminus in-in in-in ANP Type1 696 - 1019 G719S None 9
Homo sapiens EGFR_HUMAN 2ITOA 3.25 Active DFGin BLAminus in-in in-in IRE Type1 696 - 1019 G719S None 9
Homo sapiens EGFR_HUMAN 2ITPA 2.74 Active DFGin BLAminus in-in in-in AEE Type1 697 - 1018 G719S None 0
Homo sapiens EGFR_HUMAN 2ITQA 2.68 Active DFGin BLAminus in-in in-in ITQ Type1 697 - 1018 G719S None 0
Homo sapiens EGFR_HUMAN 6S9BA 3.25 Active DFGin BLAminus in-in in-in L1H Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 12
Homo sapiens EGFR_HUMAN 6S9CA 2.73 Active DFGin BLAminus in-in in-in L1K Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 12
Homo sapiens EGFR_HUMAN 6S9DA 2.67 Active DFGin BLAminus in-in in-in L3Z Type1 696 - 1017 T790M,L858R,E865A,E866A,K867A None 11
Homo sapiens EGFR_HUMAN 8HY7A 2.91 Inactive DFGin BLAminus in-out in-in NSO Type1 696 - 1019 E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 4RJ4A 2.78 Active DFGin BLAminus in-in in-in 3QW Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 4RJ7A 2.55 Active DFGin BLAminus in-in in-in 3R1 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 4RJ8A 2.5 Active DFGin BLAminus in-in in-in 3QS Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5C8KA 3.0 Active DFGin BLAminus in-in in-in 4YV Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 15
Homo sapiens EGFR_HUMAN 5C8MA 2.9 Active DFGin BLAminus in-in in-in 4YW Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5C8NA 2.401 Active DFGin BLAminus in-in in-in 4YX Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5CALA 2.7 Active DFGin BLAminus in-in in-in 4Z8 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 15
Homo sapiens EGFR_HUMAN 5CANA 2.8 Active DFGin BLAminus in-in in-in 4ZB Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5CAOA 2.6 None DFGin BLAminus in-in none-in 4ZG Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 16
Homo sapiens EGFR_HUMAN 5CAPA 2.4 Active DFGin BLAminus in-in in-in 4ZH Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 15
Homo sapiens EGFR_HUMAN 5EM7A 2.81 Active DFGin BLAminus in-in in-in 5Q4 Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5HCXA 2.6 Active DFGin BLAminus in-in in-in 60B Type1 696 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5HCZA 2.62 Active DFGin BLAminus in-in in-in 60E Type1 696 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5HIBA 2.85 Active DFGin BLAminus in-in in-in 63M Type1 696 - 1018 T790M,L858R,E865A,E866A,K867A None 5
Homo sapiens EGFR_HUMAN 6JRKA 2.796 Inactive DFGin BLAminus in-out in-in C6O Type1 696 - 1018 E865A,E866A,K867A None 15
Homo sapiens EGFR_HUMAN 2ITTA 2.73 Active DFGin BLAminus in-in in-in AEE Type1 697 - 1019 L858R None 9
Homo sapiens EGFR_HUMAN 2ITUA 2.8 Inactive DFGin BLAminus in-out in-in ITQ Type1 696 - 1019 L858R None 10
Homo sapiens EGFR_HUMAN 2ITVA 2.47 Active DFGin BLAminus in-in in-in ANP Type1 696 - 1019 L858R None 9
Homo sapiens EGFR_HUMAN 2ITZA 2.8 Inactive DFGin BLAminus in-out in-in IRE Type1 697 - 1020 L858R None 10
Homo sapiens EGFR_HUMAN 5X26A 2.951 Active DFGin BLAminus in-in in-in 7XO Type1 697 - 1020 L858R None 9
Homo sapiens EGFR_HUMAN 5X27A 2.952 Active DFGin BLAminus in-in in-in 7XR Type1 697 - 1020 L858R None 9
Homo sapiens EGFR_HUMAN 5X28A 2.952 Active DFGin BLAminus in-in in-in 7XU Type1 697 - 1020 L858R None 9
Homo sapiens EGFR_HUMAN 5XDLA 2.7 None DFGin BLAminus in-in in-none 8JC Type1 696 - 1018 L858R None 15
Homo sapiens EGFR_HUMAN 6JWLA 2.551 Active DFGin BLAminus in-in in-in YY3 Type1 696 - 1020 L858R None 6
Homo sapiens EGFR_HUMAN 4LQMA 2.5 Active DFGin BLAminus in-in in-in DJK Type1 697 - 1019 L858R None 7
Homo sapiens EGFR_HUMAN 7LGSA 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 702 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 7LGSB 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 702 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 7LGSC 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 701 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 7LGSD 3.1 Active DFGin BLAminus in-in in-in Q6K Type1 701 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 7T4JA 2.2 Active DFGin BLAminus in-in in-in R28 Type1 701 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 7T4JB 2.2 Active DFGin BLAminus in-in in-in R28 Type1 701 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 4LRMA 3.526 Active DFGin BLAminus in-in in-in YUN Type1 696 - 999 None None 0
Homo sapiens EGFR_HUMAN 4LRMB 3.526 Active DFGin BLAminus in-in in-in YUN Type1 695 - 984 None None 0
Homo sapiens EGFR_HUMAN 4LRMC 3.526 Active DFGin BLAminus in-in in-in YUN Type1 694 - 983 None None 0
Homo sapiens EGFR_HUMAN 4LRMD 3.526 Active DFGin BLAminus in-in in-in YUN Type1 696 - 981 None None 0
Homo sapiens EGFR_HUMAN 4LRME 3.526 Active DFGin BLAminus in-in in-in YUN Type1 697 - 983 None None 0
Homo sapiens EGFR_HUMAN 6JX0A 2.53 Active DFGin BLAminus in-in in-in YY3 YY3 Type1 Allosteric 701 - 989 T790M None 0
Homo sapiens EGFR_HUMAN 4G5JA 2.8 Active DFGin BLAminus in-in in-in 0WN 0WM 0WM Type1 Allosteric Allosteric 696 - 1016 None None 0
Homo sapiens EGFR_HUMAN 8D73A 2.17 Active DFGin BLAminus in-in in-in QCR Type1.5_Back 703 - 1011 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 8D73B 2.17 Active DFGin BLAminus in-in in-in QCR Type1.5_Back 704 - 1012 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 8D76A 2.4 Active DFGin BLAminus in-in in-in QFO Type1.5_Back 703 - 1014 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 8D76B 2.4 Active DFGin BLAminus in-in in-in QFO Type1.5_Back 702 - 1014 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 6D8EA 2.537 Active DFGin BLAminus in-in in-in FZP Type1.5_Back 696 - 1019 None None 5
Homo sapiens EGFR_HUMAN 8F1ZA 2.4 Active DFGin BLAminus in-in in-in X9B Type1.5_Back 695 - 1018 None None 0
Homo sapiens EGFR_HUMAN 4RJ5A 3.1 None DFGin BLAminus in-in none-in 3QY Type1.5_Back 697 - 1019 T790M,L858R,E865A,E866A,K867A None 16
Homo sapiens EGFR_HUMAN 5CAQA 2.5 Active DFGin BLAminus in-in in-in 4ZJ Type1.5_Back 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5CASA 2.1 Active DFGin BLAminus in-in in-in 4ZQ Type1.5_Back 696 - 1019 T790M,L858R,E865A,E866A,K867A None 13
Homo sapiens EGFR_HUMAN 5CAUA 2.25 Active DFGin BLAminus in-in in-in 4ZR Type1.5_Back 696 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5HCYA 2.46 Active DFGin BLAminus in-in in-in 60D Type1.5_Back 696 - 1019 T790M,L858R,E865A,E866A,K867A None 13
Homo sapiens EGFR_HUMAN 5HICA 2.6 Active DFGin BLAminus in-in in-in 63N Type1.5_Back 697 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 4R5SA 3.001 Inactive DFGin BLAminus in-out in-in FI3 Type1.5_Back 697 - 1018 L858R None 9
Homo sapiens EGFR_HUMAN 3W2OA 2.35 Inactive DFGin BLAminus out-out in-in 03P Type1.5_Front 698 - 1017 T790M,L858R None 0
Homo sapiens EGFR_HUMAN 3W2PA 2.05 Inactive DFGin BLAminus out-out in-in W2P Type1.5_Front 698 - 1018 T790M,L858R None 0
Homo sapiens EGFR_HUMAN 3W2QA 2.2 Inactive DFGin BLAminus out-out in-in HKI Type1.5_Front 698 - 1017 T790M,L858R None 0
Homo sapiens EGFR_HUMAN 5EDPA 2.9 Inactive DFGin BLAplus in-in none-in No_ligand No_ligand 697 - 1018 T790M,L858R,E865A,E866A,K867A None 15
Homo sapiens EGFR_HUMAN 5XGMA 2.952 Inactive DFGin BLAplus in-in none-out 85X Type1 696 - 1019 T790M None 16
Homo sapiens EGFR_HUMAN 6JRJA 2.943 Inactive DFGin BLAplus in-out in-none C6O Type1 696 - 1018 T790M,C797S,E865A,E866A,K867A None 15
Homo sapiens EGFR_HUMAN 5Y25A 3.102 Inactive DFGin BLAplus in-in none-in 8LU Type1 698 - 1017 T790M,L858R None 16
Homo sapiens EGFR_HUMAN 5EDRA 2.6 Inactive DFGin BLAplus in-in none-in 5N4 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 16
Homo sapiens EGFR_HUMAN 5EM5A 2.65 Inactive DFGin BLAplus in-in none-in 5Q2 Type1 697 - 1019 T790M,L858R,E865A,E866A,K867A None 16
Homo sapiens EGFR_HUMAN 2EB3A 2.84 Inactive DFGin BLAplus in-in in-in ANP Type1 696 - 1018 None None 14
Homo sapiens EGFR_HUMAN 6TFUB 2.0 Inactive DFGin BLAplus out-none none-out N7K Type1.5_Back 700 - 984 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 5EDQA 2.8 Inactive DFGin BLAplus in-in none-in 5N3 Type1.5_Back 697 - 1018 T790M,L858R,E865A,E866A,K867A None 16
Homo sapiens EGFR_HUMAN 8A27A 1.07 Inactive DFGin BLAplus out-out none-out KY9 Type3 701 - 985 None None 16
Homo sapiens EGFR_HUMAN 8A2AA 1.43 Inactive DFGin BLAplus out-out out-out KY9 Type3 700 - 1019 None None 8
Homo sapiens EGFR_HUMAN 7JXIC 3.0 Inactive DFGin BLBminus out-out none-in 8BS Type1 700 - 1007 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 4RJ6A 2.7 Inactive DFGin BLBminus in-in in-in 3R0 Type1 697 - 1018 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 5EM6A 2.78 Inactive DFGin BLBminus in-in in-in 5Q3 Type1.5_Back 697 - 1019 T790M,L858R,E865A,E866A,K867A None 14
Homo sapiens EGFR_HUMAN 8A2DA 1.11 Inactive DFGin BLBminus out-out none-in KXY Type3 701 - 1021 L858R,V948R None 10
Homo sapiens EGFR_HUMAN 6WXNA 1.76 Inactive DFGin BLBplus out-out none-out No_ligand No_ligand 699 - 1014 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7UKWA 2.6 Inactive DFGin BLBplus out-out out-in No_ligand No_ligand 702 - 1014 T790M,V948R None 2
Homo sapiens EGFR_HUMAN 7TVDA 2.96 Inactive DFGin BLBplus in-out none-out No_ligand No_ligand 698 - 1009 None None 16
Homo sapiens EGFR_HUMAN 5ZTOA 2.649 Inactive DFGin BLBplus in-in none-none 9JO Type1 697 - 1017 T790M,C797S None 17
Homo sapiens EGFR_HUMAN 6P1LB 2.8 Inactive DFGin BLBplus out-out out-out ANP Type1 702 - 1008 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 6V66D 1.79 Inactive DFGin BLBplus out-out out-in QP1 Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6KA 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 700 - 1014 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V6KC 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 700 - 1014 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V6KD 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6KF 2.2 Inactive DFGin BLBplus out-out out-out QQJ Type1 701 - 1014 T790M,V948R None 8
Homo sapiens EGFR_HUMAN 6V6KG 2.2 Inactive DFGin BLBplus out-out out-in QQJ Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6OC 2.1 Inactive DFGin BLBplus out-out out-out QQM Type1 701 - 1011 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6V6OD 2.1 Inactive DFGin BLBplus out-out out-in QQM Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6OE 2.1 Inactive DFGin BLBplus out-out out-in QQM Type1 701 - 1014 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 6V6OH 2.1 Inactive DFGin BLBplus out-out out-in QQM Type1 700 - 1014 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 6V5NA 2.4 Inactive DFGin BLBplus out-out out-in QP7 Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V5PA 2.3 Inactive DFGin BLBplus out-out out-in QP4 Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6WAKA 2.4 Inactive DFGin BLBplus out-out out-in ANP Type1 702 - 1013 T790M,V948R None 10
Homo sapiens EGFR_HUMAN 6WAKD 2.4 Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 8FV3A 2.1 Inactive DFGin BLBplus out-out out-in ANP Type1 701 - 1014 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 8FV4C 2.2 Inactive DFGin BLBplus out-out out-out ANP Type1 702 - 1013 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 4ZSED 1.97 Inactive DFGin BLBplus out-out out-in ANP Type1 701 - 1015 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 5D41B 2.31 Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 5X2AD 1.85 Inactive DFGin BLBplus out-out out-out ANP Type1 701 - 1014 T790M,V948R None 10
Homo sapiens EGFR_HUMAN 7JXKB 3.1 Inactive DFGin BLBplus out-out none-in ANP Type1 700 - 1007 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 7JXLB 2.4 Inactive DFGin BLBplus out-out out-in VO7 Type1 700 - 1005 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7JXLC 2.4 Inactive DFGin BLBplus out-out out-out VO7 Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7JXLD 2.4 Inactive DFGin BLBplus out-out out-none VO7 Type1 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXMC 2.192 Inactive DFGin BLBplus out-out out-in ANP Type1 702 - 1006 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7KY0A 3.1 Inactive DFGin BLBplus out-out out-in XA4 Type1 701 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 6TFYA 1.7 Inactive DFGin BLBplus out-out none-out N7Z Type1 699 - 982 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7A6JB 2.0 Inactive DFGin BLBplus out-out out-out R2E Type1 699 - 984 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7ZYQA 2.1 Inactive DFGin BLBplus out-none out-out V58 Type1 700 - 984 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 5FEEA 2.7 Inactive DFGin BLBplus in-in in-in 5X4 Type1 697 - 1018 T790M None 5
Homo sapiens EGFR_HUMAN 5GTYA 3.14 Inactive DFGin BLBplus out-out out-in 816 Type1 700 - 1014 T790M None 11
Homo sapiens EGFR_HUMAN 5GTYC 3.14 Inactive DFGin BLBplus out-out out-none 816 Type1 700 - 1013 T790M None 15
Homo sapiens EGFR_HUMAN 5GTYF 3.14 Inactive DFGin BLBplus out-none out-out 816 Type1 700 - 1013 T790M None 13
Homo sapiens EGFR_HUMAN 5CNOB 1.55 Inactive DFGin BLBplus out-out out-out ANP Type1 698 - 1015 V948R None 12
Homo sapiens EGFR_HUMAN 5CNNA 1.9 Inactive DFGin BLBplus out-out out-in ANP Type1 699 - 1014 I706Q None 13
Homo sapiens EGFR_HUMAN 6P1DB 2.4 Inactive DFGin BLBplus out-out out-out ANP NQ1 Type1 Type3 702 - 1013 None None 12
Homo sapiens EGFR_HUMAN 6P1LA 2.8 Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3 701 - 1007 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 6P1LC 2.8 Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3 702 - 1005 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 6P1LD 2.8 Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3 702 - 1015 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 6P8QA 1.9 Inactive DFGin BLBplus out-out out-in ANP O57 Type1 Type3 699 - 1019 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6P8QB 1.9 Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3 698 - 1007 T790M,V948R None 10
Homo sapiens EGFR_HUMAN 6P8QC 1.9 Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3 699 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6P8QD 1.9 Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3 700 - 1007 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6XL4A 2.06 Inactive DFGin BLBplus out-out out-in Q6K NQ1 Type1 Type3 700 - 1007 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 6XL4D 2.06 Inactive DFGin BLBplus out-out out-in ANP NQ1 Type1 Type3 700 - 1013 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 5D41A 2.31 Inactive DFGin BLBplus out-out none-in ANP 57N Type1 Type3 698 - 1014 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 6DUKA 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 701 - 1006 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6DUKB 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 699 - 1007 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6DUKC 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 699 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 6DUKD 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 701 - 1007 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6DUKE 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 698 - 1007 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6DUKF 2.2 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 701 - 1009 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 7JXKA 3.1 Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3 700 - 1007 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7JXKC 3.1 Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3 701 - 1007 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7JXKD 3.1 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7JXKE 3.1 Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXKF 3.1 Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXMB 2.192 Inactive DFGin BLBplus out-out none-in YY3 9LL Type1 Type3 701 - 1012 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXMD 2.192 Inactive DFGin BLBplus out-out none-in ANP 9LL Type1 Type3 700 - 1007 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7JXPA 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 7JXPB 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 7JXPD 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7JXPF 2.16 Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7JXQB 1.83 Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3 701 - 1007 T790M,V948R None 10
Homo sapiens EGFR_HUMAN 7JXQD 1.83 Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3 700 - 1007 T790M,V948R None 10
Homo sapiens EGFR_HUMAN 7JXWA 2.5 Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXWB 2.5 Inactive DFGin BLBplus out-out none-none YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7JXWC 2.5 Inactive DFGin BLBplus out-out out-in YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7JXWD 2.5 Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3 700 - 1007 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7LTXA 2.3 Inactive DFGin BLBplus out-out none-out ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7LTXB 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7LTXC 2.3 Inactive DFGin BLBplus out-out none-in ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7LTXD 2.3 Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3 700 - 1007 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 8GB4A 2.59 Inactive DFGin BLBplus out-out none-out ANP YW5 Type1 Type3 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 8GB4B 2.59 Inactive DFGin BLBplus out-out none-none ANP YW5 Type1 Type3 700 - 1007 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 8GB4C 2.59 Inactive DFGin BLBplus out-out none-out ANP YW5 Type1 Type3 700 - 1012 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 8GB4D 2.59 Inactive DFGin BLBplus out-out none-none ANP YW5 Type1 Type3 700 - 1007 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 6Z4BA 2.5 Inactive DFGin BLBplus out-none out-out Q6K 9LL Type1 Type3 700 - 982 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6Z4BB 2.5 Inactive DFGin BLBplus out-out none-out Q6K 9LL Type1 Type3 699 - 984 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 6Z4DB 2.0 Inactive DFGin BLBplus out-none none-out 8BS 57N Type1 Type3 700 - 984 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7K1IA 3.202 Inactive DFGin BLBplus out-out none-in ANP VNS Type1 Type3 700 - 1007 L858R,V948R None 17
Homo sapiens EGFR_HUMAN 5GNKA 1.796 Inactive DFGin BLBplus out-out out-out 80U Type1.5_Back 697 - 985 T790M None 12
Homo sapiens EGFR_HUMAN 6WA2A 2.4 Inactive DFGin BLBplus out-out out-out TOV Type1.5_Back 699 - 1014 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6WA2B 2.4 Inactive DFGin BLBplus out-out out-in TOV Type1.5_Back 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6WA2C 2.4 Inactive DFGin BLBplus out-out out-in TOV Type1.5_Back 701 - 1014 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6WA2D 2.4 Inactive DFGin BLBplus out-out out-in TOV Type1.5_Back 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 8FV3C 2.1 Inactive DFGin BLBplus out-out none-out YA6 Type1.5_Back 701 - 1009 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 8FV4D 2.2 Inactive DFGin BLBplus out-out out-in YAA Type1.5_Back 701 - 1005 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6TFUA 2.0 Inactive DFGin BLBplus out-out out-in N7K Type1.5_Back 700 - 982 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 6TFVA 1.5 Inactive DFGin BLBplus out-none none-in N7Q Type1.5_Back 700 - 985 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 6TFVB 1.5 Inactive DFGin BLBplus out-out none-in N7Q Type1.5_Back 698 - 984 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 6TFWA 2.0 Inactive DFGin BLBplus out-out out-in N7W Type1.5_Back 700 - 982 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 6TFWB 2.0 Inactive DFGin BLBplus out-out none-out N7W Type1.5_Back 700 - 984 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 6TFYB 1.7 Inactive DFGin BLBplus out-out none-out N7Z Type1.5_Back 699 - 984 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 6TFZA 1.8 Inactive DFGin BLBplus out-none none-in N7B Type1.5_Back 701 - 982 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 6TFZB 1.8 Inactive DFGin BLBplus out-none out-in N7B Type1.5_Back 700 - 984 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 6TG0A 1.5 Inactive DFGin BLBplus out-out none-in N78 Type1.5_Back 700 - 985 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 6TG0B 1.5 Inactive DFGin BLBplus out-out out-in N78 Type1.5_Back 698 - 984 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 6TG1A 1.6 Inactive DFGin BLBplus out-out none-out N82 Type1.5_Back 699 - 984 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 6TG1B 1.6 Inactive DFGin BLBplus out-none none-out N82 Type1.5_Back 698 - 984 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 2JIVB 3.5 Inactive DFGin BLBplus out-out out-out HKI Type1.5_Back 699 - 982 T790M None 11
Homo sapiens EGFR_HUMAN 5GTYB 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 700 - 1014 T790M None 12
Homo sapiens EGFR_HUMAN 5GTYD 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 701 - 1014 T790M None 12
Homo sapiens EGFR_HUMAN 5GTYE 3.14 Inactive DFGin BLBplus out-none out-out 816 Type1.5_Back 701 - 1014 T790M None 12
Homo sapiens EGFR_HUMAN 5GTYG 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 699 - 1014 T790M None 12
Homo sapiens EGFR_HUMAN 5GTYH 3.14 Inactive DFGin BLBplus out-out out-out 816 Type1.5_Back 700 - 1016 T790M None 12
Homo sapiens EGFR_HUMAN 3W2RA 2.05 Inactive DFGin BLBplus out-out out-in W2R Type1.5_Back 698 - 1017 T790M,L858R None 14
Homo sapiens EGFR_HUMAN 2RGPA 2.0 Inactive DFGin BLBplus out-out out-in HYZ Type1.5_Back 702 - 1016 None None 8
Homo sapiens EGFR_HUMAN 3BELA 2.3 Inactive DFGin BLBplus out-out out-in POX Type1.5_Back 702 - 1015 None None 8
Homo sapiens EGFR_HUMAN 3LZBA 2.7 Inactive DFGin BLBplus out-out none-out ITI Type1.5_Back 703 - 983 V948R None 16
Homo sapiens EGFR_HUMAN 3LZBB 2.7 Inactive DFGin BLBplus out-out none-in ITI Type1.5_Back 703 - 983 V948R None 16
Homo sapiens EGFR_HUMAN 3LZBC 2.7 Inactive DFGin BLBplus out-out none-in ITI Type1.5_Back 704 - 983 V948R None 16
Homo sapiens EGFR_HUMAN 3LZBD 2.7 Inactive DFGin BLBplus out-out none-in ITI Type1.5_Back 703 - 983 V948R None 16
Homo sapiens EGFR_HUMAN 3POZA 1.5 Inactive DFGin BLBplus out-out out-in 03P Type1.5_Back 701 - 1017 None None 7
Homo sapiens EGFR_HUMAN 3W2SA 1.9 Inactive DFGin BLBplus out-out out-out W2R Type1.5_Back 701 - 1019 None None 12
Homo sapiens EGFR_HUMAN 3W32A 1.8 Inactive DFGin BLBplus out-out out-in W32 Type1.5_Back 701 - 1017 None None 0
Homo sapiens EGFR_HUMAN 3W33A 1.7 Inactive DFGin BLBplus out-out out-in W19 Type1.5_Back 701 - 1018 None None 12
Homo sapiens EGFR_HUMAN 1XKKA 2.4 Inactive DFGin BLBplus out-out out-out FMM Type1.5_Back 702 - 1018 None None 8
Homo sapiens EGFR_HUMAN 6WAKC 2.4 Inactive DFGin BLBplus out-out none-out TQA Type1.5_Front 701 - 1014 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 6WXNC 1.76 Inactive DFGin BLBplus out-out none-out UEJ Type1.5_Front 701 - 1014 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 6WXND 1.76 Inactive DFGin BLBplus out-out out-in UEJ Type1.5_Front 702 - 1014 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 7LG8B 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type1.5_Front Type1 702 - 1002 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 5ZWJA 2.9 Inactive DFGin BLBplus out-none none-out 9LL Type3 702 - 985 T790M,C797S,V948R None 17
Homo sapiens EGFR_HUMAN 8A2BA 1.69 Inactive DFGin BLBplus out-out none-out KY9 Type3 702 - 990 L858R,V948R None 17
Homo sapiens EGFR_HUMAN 6P1DC 2.4 Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1 702 - 1006 None None 13
Homo sapiens EGFR_HUMAN 6P1DD 2.4 Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1 701 - 1008 None None 13
Homo sapiens EGFR_HUMAN 6XL4B 2.06 Inactive DFGin BLBplus out-out none-in NQ1 Q6K Type3 Type1 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXPC 2.16 Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXPE 2.16 Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1 700 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 7JXQA 1.83 Inactive DFGin BLBplus out-out out-out VNS ANP Type3 Type1 700 - 1007 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 7JXQC 1.83 Inactive DFGin BLBplus out-out out-in VNS ANP Type3 Type1 700 - 1007 T790M,V948R None 10
Homo sapiens EGFR_HUMAN 7LG8A 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1 702 - 1006 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7LG8C 2.93 Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1 703 - 1004 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 7LG8D 2.93 Inactive DFGin BLBplus out-out none-out VNS 8RC Type3 Type1 702 - 1003 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7A2AA 1.9 Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1 700 - 984 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7A2AB 1.9 Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1 699 - 984 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 7K1HA 2.602 Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 16
Homo sapiens EGFR_HUMAN 7K1HB 2.602 Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1 701 - 1008 L858R,V948R None 17
Homo sapiens EGFR_HUMAN 7K1HC 2.602 Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 17
Homo sapiens EGFR_HUMAN 7K1HD 2.602 Inactive DFGin BLBplus out-out out-out VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 15
Homo sapiens EGFR_HUMAN 7K1HE 2.602 Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1 703 - 1007 L858R,V948R None 16
Homo sapiens EGFR_HUMAN 7K1HF 2.602 Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1 701 - 1007 L858R,V948R None 17
Homo sapiens EGFR_HUMAN 6XL4C 2.06 Inactive DFGin BLBtrans out-out out-in No_ligand No_ligand 700 - 1011 T790M,V948R None 7
Homo sapiens EGFR_HUMAN 7UKWD 2.6 Inactive DFGin BLBtrans out-out out-in No_ligand No_ligand 702 - 1012 T790M,V948R None 6
Homo sapiens EGFR_HUMAN 8FV4B 2.2 Inactive DFGin BLBtrans out-out out-in No_ligand No_ligand 702 - 1007 T790M,V948R None 3
Homo sapiens EGFR_HUMAN 2RFDA 3.6 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 K823E None 11
Homo sapiens EGFR_HUMAN 2RFDB 3.6 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 K823E None 8
Homo sapiens EGFR_HUMAN 2RFEA 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 702 - 1002 K823E None 8
Homo sapiens EGFR_HUMAN 2RFEB 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1012 K823E None 11
Homo sapiens EGFR_HUMAN 2RFEC 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 702 - 983 K823E None 11
Homo sapiens EGFR_HUMAN 2RFED 2.9 Inactive DFGin BLBtrans out-out out-out No_ligand No_ligand 703 - 1018 K823E None 11
Homo sapiens EGFR_HUMAN 6P1DA 2.4 Inactive DFGin BLBtrans out-out out-in ANP Type1 700 - 1021 None None 13
Homo sapiens EGFR_HUMAN 6V66A 1.79 Inactive DFGin BLBtrans out-out out-in QP1 Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V66B 1.79 Inactive DFGin BLBtrans out-out out-out QP1 Type1 701 - 1014 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6V66C 1.79 Inactive DFGin BLBtrans out-out out-in QP1 Type1 701 - 1012 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V6KB 2.2 Inactive DFGin BLBtrans out-out out-none QQJ Type1 700 - 1014 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 6V6KE 2.2 Inactive DFGin BLBtrans out-out out-in QQJ Type1 701 - 1014 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 6V6KH 2.2 Inactive DFGin BLBtrans out-out out-out QQJ Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6OA 2.1 Inactive DFGin BLBtrans out-out out-in QQM Type1 701 - 1007 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6OB 2.1 Inactive DFGin BLBtrans out-out out-out QQM Type1 701 - 1014 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V6OF 2.1 Inactive DFGin BLBtrans out-out out-in QQM Type1 701 - 1012 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V6OG 2.1 Inactive DFGin BLBtrans out-out out-in QQM Type1 701 - 1009 T790M,V948R None 15
Homo sapiens EGFR_HUMAN 6V5NB 2.4 Inactive DFGin BLBtrans out-out out-in QP7 Type1 700 - 1008 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 6V5NC 2.4 Inactive DFGin BLBtrans out-out out-out QP7 Type1 701 - 1007 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V5ND 2.4 Inactive DFGin BLBtrans out-out out-in QP7 Type1 701 - 1008 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6V5PB 2.3 Inactive DFGin BLBtrans out-out out-out QP4 Type1 701 - 1012 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V5PC 2.3 Inactive DFGin BLBtrans out-out out-in QP4 Type1 701 - 1008 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 6V5PD 2.3 Inactive DFGin BLBtrans out-out out-in QP4 Type1 701 - 1008 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 6WAKB 2.4 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1020 T790M,V948R None 4
Homo sapiens EGFR_HUMAN 6WXNB 1.76 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1021 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 7UKWB 2.6 Inactive DFGin BLBtrans out-out none-in ZRT Type1 702 - 1010 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7UKWC 2.6 Inactive DFGin BLBtrans out-out out-in ZRT Type1 700 - 1005 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 8FV3B 2.1 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1021 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 8FV3D 2.1 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1008 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 8FV4A 2.2 Inactive DFGin BLBtrans out-out out-out ANP Type1 701 - 1013 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 4ZSEA 1.97 Inactive DFGin BLBtrans out-out out-in ANP Type1 699 - 1007 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 4ZSEB 1.97 Inactive DFGin BLBtrans out-out out-in ANP Type1 698 - 1022 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 4ZSEC 1.97 Inactive DFGin BLBtrans out-out out-in ANP Type1 700 - 1013 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 5X2AC 1.85 Inactive DFGin BLBtrans out-out out-out 7XO Type1 700 - 1015 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 5X2CA 2.05 Inactive DFGin BLBtrans out-out out-out 7XR Type1 700 - 1015 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 5X2CB 2.05 Inactive DFGin BLBtrans out-out out-out 7XR Type1 701 - 1014 T790M,V948R None 11
Homo sapiens EGFR_HUMAN 5X2FA 2.2 Inactive DFGin BLBtrans out-out out-out 7XU Type1 700 - 1014 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 5X2FB 2.2 Inactive DFGin BLBtrans out-out out-in 7XU Type1 699 - 1010 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 5X2FC 2.2 Inactive DFGin BLBtrans out-out out-in 7XU Type1 700 - 1014 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 5X2FD 2.2 Inactive DFGin BLBtrans out-out out-out 7XU Type1 697 - 1014 T790M,V948R None 7
Homo sapiens EGFR_HUMAN 7JXIA 3.0 Inactive DFGin BLBtrans out-out none-in 8BS Type1 700 - 1006 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7JXID 3.0 Inactive DFGin BLBtrans out-out out-in 8BS Type1 702 - 1006 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 7JXLA 2.4 Inactive DFGin BLBtrans out-out out-in VO7 Type1 701 - 1013 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7JXMA 2.192 Inactive DFGin BLBtrans out-out out-in ANP Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7KY0B 3.1 Inactive DFGin BLBtrans out-out out-out XA4 Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7KY0D 3.1 Inactive DFGin BLBtrans out-out out-in XA4 Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7U98B 3.42 Inactive DFGin BLBtrans out-out out-out M1O Type1 701 - 1005 T790M,V948R None 12
Homo sapiens EGFR_HUMAN 7U98C 3.42 Inactive DFGin BLBtrans out-out out-out M1O Type1 702 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7U98D 3.42 Inactive DFGin BLBtrans out-out none-out M1O Type1 701 - 1007 T790M,V948R None 16
Homo sapiens EGFR_HUMAN 8F1WA 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 701 - 1007 T790M,V948R None 4
Homo sapiens EGFR_HUMAN 8F1WB 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 8F1WC 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 8F1WD 3.2 Inactive DFGin BLBtrans out-out out-in R2E Type1 700 - 1007 T790M,V948R None 4
Homo sapiens EGFR_HUMAN 6Z4DA 2.0 Inactive DFGin BLBtrans out-out out-out 8BS Type1 701 - 984 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 7A6JA 2.0 Inactive DFGin BLBtrans out-out out-out R2E Type1 699 - 982 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7A6KA 2.0 Inactive DFGin BLBtrans out-out out-out R28 Type1 700 - 984 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7A6KB 2.0 Inactive DFGin BLBtrans out-none none-out R28 Type1 700 - 982 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7A6KC 2.0 Inactive DFGin BLBtrans out-none none-out R28 Type1 700 - 984 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7A6KD 2.0 Inactive DFGin BLBtrans out-out none-out R28 Type1 702 - 984 T790M,V948R None 18
Homo sapiens EGFR_HUMAN 4I24A 1.8 Inactive DFGin BLBtrans out-out out-out 1C9 Type1 700 - 1014 T790M None 13
Homo sapiens EGFR_HUMAN 4I24B 1.8 Inactive DFGin BLBtrans out-out out-in 1C9 Type1 700 - 1014 T790M None 11
Homo sapiens EGFR_HUMAN 5YU9A 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 700 - 1017 T790M None 12
Homo sapiens EGFR_HUMAN 5YU9B 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 699 - 1011 T790M None 13
Homo sapiens EGFR_HUMAN 5YU9C 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 697 - 1021 T790M None 12
Homo sapiens EGFR_HUMAN 5YU9D 1.95 Inactive DFGin BLBtrans out-out out-out 1E8 Type1 700 - 1012 T790M None 13
Homo sapiens EGFR_HUMAN 4I22A 1.71 Inactive DFGin BLBtrans out-out out-out IRE Type1 700 - 1014 T790M,L858R,V948R None 13
Homo sapiens EGFR_HUMAN 2GS7A 2.6 Inactive DFGin BLBtrans out-out out-out ANP Type1 703 - 1012 V948R None 4
Homo sapiens EGFR_HUMAN 2GS7B 2.6 Inactive DFGin BLBtrans out-out out-in ANP Type1 701 - 1016 V948R None 3
Homo sapiens EGFR_HUMAN 3GT8A 2.955 Inactive DFGin BLBtrans out-out out-none ANP Type1 700 - 1014 V948R None 15
Homo sapiens EGFR_HUMAN 3GT8B 2.955 Inactive DFGin BLBtrans out-out out-none ANP Type1 701 - 1007 V948R None 15
Homo sapiens EGFR_HUMAN 3GT8C 2.955 Inactive DFGin BLBtrans out-out out-in ANP Type1 699 - 1007 V948R None 13
Homo sapiens EGFR_HUMAN 3GT8D 2.955 Inactive DFGin BLBtrans out-out out-none ANP Type1 701 - 1010 V948R None 15
Homo sapiens EGFR_HUMAN 5CNOA 1.55 Inactive DFGin BLBtrans out-out out-out ANP Type1 700 - 1015 V948R None 11
Homo sapiens EGFR_HUMAN 4HJOA 2.75 Inactive DFGin BLBtrans out-out out-out AQ4 Type1 703 - 984 V948R None 0
Homo sapiens EGFR_HUMAN 5CNNB 1.9 Inactive DFGin BLBtrans out-out out-out ANP Type1 700 - 1014 I706Q None 11
Homo sapiens EGFR_HUMAN 6JXTA 2.307 Inactive DFGin BLBtrans out-out out-in YY3 Type1 697 - 984 E865A,E866A,K867A None 2
Homo sapiens EGFR_HUMAN 5X2AA 1.85 Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Allosteric 700 - 1011 T790M,V948R None 13
Homo sapiens EGFR_HUMAN 5X2AB 1.85 Inactive DFGin BLBtrans out-out out-in 7XO ANP Type1 Type1 700 - 1022 T790M,V948R None 0
Homo sapiens EGFR_HUMAN 8EMEA 3.32 Inactive DFGin None out-out none-none No_ligand No_ligand 700 - 1007 T790M,V948R None 21
Homo sapiens EGFR_HUMAN 3GOPA 2.8 Inactive DFGin None in-none none-in No_ligand No_ligand 676 - 1018 K745M None 18
Homo sapiens EGFR_HUMAN 7JXIB 3.0 Inactive DFGin None out-out none-in 8BS Type1 702 - 1004 T790M,V948R None 17
Homo sapiens EGFR_HUMAN 7KY0C 3.1 Inactive DFGin None out-out out-in XA4 Type1 700 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7U98A 3.42 Inactive DFGin None out-out out-none M1O Type1 701 - 1007 T790M,V948R None 14
Homo sapiens EGFR_HUMAN 7ZYQB 2.1 Inactive DFGin None out-out none-out V58 Type1 700 - 984 T790M,V948R None 19
Homo sapiens EGFR_HUMAN 4RIWB 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 4
Homo sapiens EGFR_HUMAN 4RIWD 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 0
Homo sapiens EGFR_HUMAN 4RIXB 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 4
Homo sapiens EGFR_HUMAN 4RIXD 3.1 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 0
Homo sapiens EGFR_HUMAN 4RIYB 2.981 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 4
Homo sapiens EGFR_HUMAN 4RIYD 2.981 Inactive DFGin None in-in in-in ADP Type1 688 - 984 V948R,F997A,L1001A None 0
Homo sapiens EGFR_HUMAN 2JIVA 3.5 Inactive DFGin None out-out out-in HKI Type1.5_Back 700 - 984 T790M None 14
Homo sapiens EGFR_HUMAN 8H7XB 3.404 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1018 T790M,C797S None 7
Homo sapiens EGFR_HUMAN 5XGNB 3.0 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1019 T790M,C797S None 4
Homo sapiens EGFR_HUMAN 2JITB 3.1 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1018 T790M None 0
Homo sapiens EGFR_HUMAN 2JIUB 3.05 Inactive DFGinter None in-in in-in No_ligand No_ligand 695 - 1004 T790M None 0
Homo sapiens EGFR_HUMAN 4G5PB 3.17 Inactive DFGinter None in-in out-out No_ligand No_ligand 697 - 1018 T790M None 8
Homo sapiens EGFR_HUMAN 3IKAB 2.9 Inactive DFGinter None in-in out-in No_ligand No_ligand 697 - 1017 T790M None 2
Homo sapiens EGFR_HUMAN 4WD5B 3.3 Inactive DFGinter None in-out out-out No_ligand No_ligand 697 - 1016 T790M None 5
Homo sapiens EGFR_HUMAN 5UWDA 3.06 Inactive DFGinter None out-out out-out 8OV Type1 702 - 984 T790M,L858R,V948R None 12
Homo sapiens EGFR_HUMAN 2RF9A 3.5 Inactive DFGout BBAminus out-none in-in No_ligand No_ligand 699 - 983 None None 2
Homo sapiens EGFR_HUMAN 4ZJVA 2.7 Inactive DFGout BBAminus out-out in-in No_ligand No_ligand 703 - 985 None None 0
Homo sapiens EGFR_HUMAN 4ZJVB 2.7 Inactive DFGout BBAminus out-out in-in No_ligand No_ligand 703 - 982 None None 0
Homo sapiens EGFR_HUMAN 5HG5A 1.52 Inactive DFGout BBAminus out-out in-in 633 Type1 700 - 1001 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5HG7A 1.85 Inactive DFGout BBAminus out-out in-in 630 Type1 702 - 984 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5HG8A 1.42 Inactive DFGout BBAminus out-out in-in 634 Type1 700 - 999 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5HG9A 2.15 Inactive DFGout BBAminus out-out in-in 63A Type1 702 - 985 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5U8LA 1.6 Inactive DFGout BBAminus out-out in-in O44 Type1 702 - 990 None None 0
Homo sapiens EGFR_HUMAN 5UG8A 1.46 Inactive DFGout BBAminus out-out in-in 8BP Type1 702 - 985 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5UG9A 1.33 Inactive DFGout BBAminus out-out in-in 8AM Type1 702 - 985 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5UGAA 1.82 Inactive DFGout BBAminus out-out in-in 8BM Type1 703 - 985 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 5UGCA 1.58 Inactive DFGout BBAminus out-out in-in 8BS Type1 702 - 985 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 4I1ZA 3.0 Inactive DFGout None out-out in-in No_ligand No_ligand 701 - 987 T790M,L858R,V948R None 0
Homo sapiens EGFR_HUMAN 4I21A 3.37 Inactive DFGout None out-out in-in No_ligand No_ligand 703 - 1019 T790M,L858R None 0
Homo sapiens EGFR_HUMAN 4I21B 3.37 Inactive DFGout None out-out in-in No_ligand No_ligand 703 - 1020 T790M,L858R None 0
Homo sapiens EGFR_HUMAN 2RF9B 3.5 Inactive DFGout None out-none in-out No_ligand No_ligand 701 - 985 None None 6
Homo sapiens EGFR_HUMAN 4I20A 3.34 Inactive DFGout None out-out in-in No_ligand No_ligand 701 - 987 L858R,V948R None 0
Homo sapiens EGFR_HUMAN 8DSWA 2.39 Inactive None None none-none in-in ANP Type1 696 - 1017 None None 9

EGFR (Epidermal growth factor receptor)

No non-human structures known.