| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | None | DFGin | BLAminus | in-none | in-in | VX6 | Type1 | 280 - 545 | 0 |
| B | None | DFGin | BLAminus | in-none | in-in | VX6 VX6 VX6 | Type1 Allosteric Allosteric | 280 - 545 | 0 |
| C | None | DFGin | BLAminus | in-none | in-in | VX6 VX6 VX6 | Type1 Allosteric Allosteric | 281 - 544 | 0 |
Representative sequence - Chain C
- - 284 294
mghhhhhhss gvdlgtenly fqsmdkWEME RTDITMKHKL
304 314 324 334
GGGQYGEVYV GVWKKYSLTV AVKTLKedTM EVEEFLKEAA
344 354 364 374
VMKEIKHPNL VQLLGVCTLE PPFYIVTEYM PYGNLLDYLR
384 394 404 414
ECNREEVTAV VLLYMATQIS SAMEYLEKKN FIHRDLAARN
424 434 444 454
CLVGENHVVK VADFGLSRLM TGDTYTAHAG AKFPIKWTAP
464 474 484 494
ESLAYNTFSI KSDVWAFGVL LWEIATYGMS PYPGIDLSQV
504 514 524 534
YDLLEKGYRM EQPEGCPPKV YELMRACWKW SPADRPSFAE
544
THQAFETMFH ds