Human protein kinases in complex with Type3 ligands

Total number of genes: 26
Total number of chains: 260
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Total
DFGin BLAminus 0 0 0 5 0 0 0 3 1 6 15
DFGin BLAplus 0 0 0 0 0 0 0 0 2 0 2
DFGin ABAminus 0 0 0 0 0 0 0 0 0 0 0
DFGin BLBminus 0 0 0 17 0 0 0 0 1 0 18
DFGin BLBplus 0 0 0 0 0 0 54 0 68 0 122
DFGin BLBtrans 0 0 0 0 0 0 0 0 0 0 0
DFGin None 0 1 0 0 0 0 0 0 0 0 1
DFGinter BABtrans 0 0 0 0 0 0 0 0 0 0 0
DFGinter None 0 0 0 2 0 0 0 0 0 0 2
DFGout BBAminus 1 0 0 14 0 0 8 32 20 0 75
DFGout None 0 0 0 5 0 0 1 1 14 3 24
None None 0 0 0 1 0 0 0 0 0 0 1
Total - 1 1 0 44 0 0 63 36 106 9 260

Download as tsv


Group Gene UniprotID Protein PDB Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActloopCT Ligand Type
AGC AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 8Q61A Inactive DFGout BBAminus out-out out-none K06 Type3
CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 8BFMA Inactive DFGin None out-none none-none QI6 QI6 Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXFA Inactive DFGin BLBminus out-out out-out 2AN 2AN Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXZA Inactive DFGin BLBminus out-out out-out 2AN 2AN JWS Allosteric Type3 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXQA Inactive DFGin BLBminus out-out out-out 2AN 2AN 2AN Type1 Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY1A Inactive DFGin BLBminus out-out out-out SU9 2AN 2AN Type1 Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWEA Inactive DFGin BLBminus none-none none-none 7TH 7TH Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7SA0A Inactive DFGin BLBminus out-out out-out 8KQ 8KQ Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FOWA Inactive DFGin BLBminus out-out out-out 1QK 7TW Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP0A Inactive DFGin BLBminus out-out out-out RRC 7TW Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ7A Inactive DFGin BLBminus out-out out-out STU 2AN 2AN Type1 Type3 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RXOA Inactive DFGin BLBminus out-none out-out 80E Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S4TA Inactive DFGin BLBminus out-out out-out 88O Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S7AA Inactive DFGin BLBminus out-none out-out 8FI Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S84A Inactive DFGin BLBminus out-out out-out 8IL Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S85A Inactive DFGin BLBminus out-out out-out 8IQ Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S9XA Inactive DFGin BLBminus out-out out-out 8KF Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWFA Inactive DFGin BLBminus out-out out-out 7TW Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UG1A Inactive DFGin BLBminus out-out out-out N5R N5R Type3 Allosteric
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F6SA Inactive DFGout BBAminus in-in none-out 0SQ Type3
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F7JA Inactive DFGout BBAminus in-in none-out 0SU Type3
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F70A Inactive None None in-in none-out 0ST Type3
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QA4A Inactive DFGin BLAminus out-out in-in HRZ HRZ HRZ HRZ Allosteric Type1 Allosteric Type3
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAQA Inactive DFGin BLAminus out-out in-in HVQ HVQ Type3 Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3IW8A Inactive DFGout BBAminus in-in none-out HIZ Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFBA Inactive DFGout BBAminus in-in none-out Z87 Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFCA Inactive DFGout BBAminus in-in none-out Z86 Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNVA Inactive DFGout BBAminus in-in out-out 437 Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNXA Inactive DFGout BBAminus in-in out-out EDD Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1W82A Inactive DFGout BBAminus in-in out-out L10 Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1WBVA Inactive DFGout BBAminus in-in out-out LI3 Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HV7A Inactive DFGout BBAminus in-in none-out 1AU Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2BAJA Inactive DFGout BBAminus in-in out-out 1PP Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3O8UA Inactive DFGout BBAminus in-in none-out BMU Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OBJA Inactive DFGout BBAminus in-out none-out BMU Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3IA Inactive DFGout BBAminus in-in none-out JZJ I46 I46 Type3 Allosteric Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFDA Inactive DFGout None in-in none-out Z85 Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1KV1A Inactive DFGout None in-in none-out BMU Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3O8TA Inactive DFGout None in-out none-out BMU Type3
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OC1A Inactive DFGout None in-in none-out BMU Type3
CMGC MAPK7 MK07_HUMAN Mitogen-activated protein kinase 7 4ZSLA Inactive DFGin BLAminus out-out in-in 4QZ Type3
CMGC MAPK7 MK07_HUMAN Mitogen-activated protein kinase 7 4ZSJA Inactive DFGin BLAminus in-out in-in 4R0 Type3
CMGC MAPK7 MK07_HUMAN Mitogen-activated protein kinase 7 4ZSGA Inactive DFGin BLAminus in-out in-in 4QX Type3
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9A Inactive DFGout None out-out none-out 4K7 Type3
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9B Inactive DFGout None out-out none-none 4K7 Type3
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9C Inactive DFGout None out-out none-none 4K7 Type3
OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYA None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYB None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8A Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8B Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9A Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9B Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN3A Inactive DFGin BLBplus out-out out-out ATP 5Y0 Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN9A Inactive DFGin BLBplus out-out out-out ACP 2P7 Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3SLSA Inactive DFGin BLBplus out-out out-out ANP 77D Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3SLSB Inactive DFGin BLBplus out-out out-out ANP 77D Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B3MA Inactive DFGin BLBplus out-out out-out ANP SU5 Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B3MB Inactive DFGin BLBplus out-out out-out ANP SU5 Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B7RA Inactive DFGin BLBplus out-out out-out ANP T1K Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B7RB Inactive DFGin BLBplus out-out out-none ANP T1K Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B94A Inactive DFGin BLBplus out-out out-out ANP T3W Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B94B Inactive DFGin BLBplus out-out out-none ANP T3W Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B9LA Inactive DFGin BLBplus out-out out-none ANP T4N Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B9LB Inactive DFGin BLBplus out-out out-none ANP T4N Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3ORNA Inactive DFGin BLBplus out-out out-out ANP 3OR Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3OS3A Inactive DFGin BLBplus out-out out-out ATP 3OS Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3WIGA Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DV3A Inactive DFGin BLBplus out-out out-out ATP MEK Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3MBLA Inactive DFGin BLBplus out-out out-out ADP LSG Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3PP1A Inactive DFGin BLBplus out-out out-out ATP IZG Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQBA Inactive DFGin BLBplus out-out out-out ATP LUG Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U80A Inactive DFGin BLBplus out-out out-out ANP 3EX Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 1S9JA Inactive DFGin BLBplus out-out out-out ATP BBM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DY7A Inactive DFGin BLBplus out-out out-out ATP 1CX Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3E8NA Inactive DFGin BLBplus out-out out-out ATP VRA Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHA Inactive DFGin BLBplus out-out out-none ATP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHB Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHC Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4ARKA Inactive DFGin BLBplus out-out out-out ADP M3K Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4LMNA Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4MNEE Inactive DFGin BLBplus out-out out-out ACP 573 Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQGA Inactive DFGin BLBplus out-out out-out ADP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7UMBC Inactive DFGin BLBplus out-out out-out ANP U9F Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 6PP9B Inactive DFGin BLBplus out-out out-out ANP LCJ Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0VB Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0WB Inactive DFGin BLBplus out-out out-out ANP QOA Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0XB Inactive DFGin BLBplus out-out out-out ANP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0YB Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0ZB Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8DGTB Inactive DFGin BLBplus out-out out-out AGS LCJ Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 6NYBB Inactive DFGin BLBplus out-out out-out ADP LCJ Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4MNEH Inactive DFGin BLBplus out-out out-out ACP 573 573 Type1 Type3 Allosteric
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7MFDB Inactive DFGin BLBplus out-out out-out CHU Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN2A Inactive DFGin BLBplus out-out out-out EUI ACP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4ANBA Inactive DFGin BLBplus out-out out-out YQY ACP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 2P55A Inactive DFGin BLBplus out-out out-out MRA ATP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U7ZA Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U81A Inactive DFGin BLBplus out-out out-out 3EY ANP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V01A Inactive DFGin BLBplus out-out out-out 3V0 ATP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V04A Inactive DFGin BLBplus out-out out-out V04 ATP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQCA Inactive DFGin BLBplus out-out out-out 3BM AGS Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQHA Inactive DFGin BLBplus out-out out-out 5BM ADP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0TB Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0UB Inactive DFGin BLBplus out-out out-out QO7 ANP Type3 Type1
STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IA Inactive DFGin BLBplus out-out out-out ATP 5EA Type1 Type3
STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IB Inactive DFGin BLBplus out-out out-none ATP 5EA Type1 Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJIA Inactive DFGout BBAminus out-out out-in 4OQ Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJIB Inactive DFGout BBAminus out-out out-in 4OQ Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJIC Inactive DFGout BBAminus out-out out-out 4OQ Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJID Inactive DFGout BBAminus out-out in-out 4OQ Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJA Inactive DFGout BBAminus out-out out-in 4OR Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJB Inactive DFGout BBAminus out-out out-in 4OR Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJC Inactive DFGout BBAminus out-none none-out 4OR Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJD Inactive DFGout BBAminus out-none none-out 4OR Type3
STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZLOA Inactive DFGout None out-out none-out 4PV Type3
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7LB Inactive DFGin BLAminus in-out in-in LU8 XHJ XHJ XHJ XHJ Type1 Allosteric Allosteric Allosteric Type3
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S83A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJY Type1 Allosteric Allosteric Type3
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S9KB Inactive DFGin BLAminus in-out in-in LU8 YV4 Type1 Type3
TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUA Inactive DFGout BBAminus out-out out-out RXN Type3
TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUB Inactive DFGout BBAminus out-out out-out RXN Type3
TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUC Inactive DFGout BBAminus out-none out-none RXN Type3
TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUD Inactive DFGout BBAminus out-none out-out RXN Type3
TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 4TPTA Inactive DFGout BBAminus out-out out-in 35H Type3
TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 4TPTB Inactive DFGout BBAminus out-out out-in 35H Type3
TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 5NXDB Inactive DFGout BBAminus out-out out-none 9D8 Type3
TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 5NXDA Inactive DFGout None out-out out-none 9D8 Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C3EA Inactive DFGout BBAminus out-out out-out EJY Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITHA Inactive DFGout BBAminus out-out out-out RCM Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITHB Inactive DFGout BBAminus out-out out-out RCM Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITIA Inactive DFGout BBAminus out-out out-out 1HW Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITIB Inactive DFGout BBAminus out-out out-out 1HW Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NYHA Inactive DFGout BBAminus out-out out-out L8D Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NYHB Inactive DFGout BBAminus out-out out-out L8D Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 7FCZA Inactive DFGout BBAminus out-out out-out 3IF Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 7FCZB Inactive DFGout BBAminus out-out out-out 3IF Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DA Inactive DFGout BBAminus out-out out-out EJP Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DB Inactive DFGout BBAminus out-out out-out EJP Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DC Inactive DFGout BBAminus out-out out-out EJP Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DD Inactive DFGout BBAminus out-out out-out EJP Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 5HX6A Inactive DFGout BBAminus out-out out-out 65U Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 5TX5A Inactive DFGout BBAminus out-out out-out 7MJ Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6HHOA Inactive DFGout BBAminus out-out out-out G4W Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6HHOB Inactive DFGout BBAminus out-out out-none G4W Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6OCQB Inactive DFGout BBAminus out-out out-none M5J Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FA Inactive DFGout BBAminus out-out out-none JSW Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FB Inactive DFGout BBAminus out-out out-out JSW Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FC Inactive DFGout BBAminus out-out out-out JSW Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FD Inactive DFGout BBAminus out-out out-out JSW Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6RLNA Inactive DFGout BBAminus out-out out-out K8K Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NW2A Inactive DFGout BBAminus out-out out-none L4Y Type3
TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NW2B Inactive DFGout BBAminus out-out out-out L4Y Type3
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRKA Inactive DFGout BBAminus in-in out-in 9DP Type3
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 7FEHA Inactive DFGout BBAminus in-in out-in 3UI Type3
TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5BVKA Inactive DFGout None in-in out-in 4VC Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A27A Inactive DFGin BLAplus out-out none-out KY9 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2AA Inactive DFGin BLAplus out-out out-out KY9 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2DA Inactive DFGin BLBminus out-out none-in KXY Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1DB Inactive DFGin BLBplus out-out out-out ANP NQ1 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1LA Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1LC Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1LD Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QA Inactive DFGin BLBplus out-out out-in ANP O57 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QB Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QC Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QD Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6XL4A Inactive DFGin BLBplus out-out out-in Q6K NQ1 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6XL4D Inactive DFGin BLBplus out-out out-in ANP NQ1 Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5D41A Inactive DFGin BLBplus out-out none-in ANP 57N Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKA Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKB Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKC Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKD Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKE Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKF Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKA Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKC Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKD Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKE Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKF Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXMB Inactive DFGin BLBplus out-out none-in YY3 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXMD Inactive DFGin BLBplus out-out none-in ANP 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPA Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPB Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPD Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPF Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQB Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQD Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWA Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWB Inactive DFGin BLBplus out-out none-none YY3 VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWC Inactive DFGin BLBplus out-out out-in YY3 VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWD Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXA Inactive DFGin BLBplus out-out none-out ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXB Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXC Inactive DFGin BLBplus out-out none-in ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXD Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6Z4BA Inactive DFGin BLBplus out-none out-out Q6K 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6Z4BB Inactive DFGin BLBplus out-out none-out Q6K 9LL Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6Z4DB Inactive DFGin BLBplus out-none none-out 8BS 57N Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1IA Inactive DFGin BLBplus out-out none-in ANP VNS Type1 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5ZWJA Inactive DFGin BLBplus out-none none-out 9LL Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2BA Inactive DFGin BLBplus out-out none-out KY9 Type3
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1DC Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1DD Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6XL4B Inactive DFGin BLBplus out-out none-in NQ1 Q6K Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPC Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPE Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQA Inactive DFGin BLBplus out-out out-out VNS ANP Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQC Inactive DFGin BLBplus out-out out-in VNS ANP Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8A Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8C Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8D Inactive DFGin BLBplus out-out none-out VNS 8RC Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7A2AA Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7A2AB Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HA Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HB Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HC Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HD Inactive DFGin BLBplus out-out out-out VNS YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HE Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HF Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1
TYR EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 6IN0A Inactive DFGin BLAminus in-out in-in O4B O4B Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0A Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0B Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0C Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0D Inactive DFGout None in-out out-in CCX CCX Type3 Allosteric
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M0YA Inactive DFGin BLBplus out-out out-out M0Y M0Y Type1 Type3
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M14A Inactive DFGin BLBplus out-out out-out QWS QWS Type1 Type3
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M12A Inactive DFGin BLBplus out-out out-out 1YZ Type3
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M13A Inactive DFGin BLBplus out-out out-out 1E0 Type3
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M0ZA Inactive DFGin BLBplus out-out out-out M0Z M0Z Type3 Type1
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M15A Inactive DFGin BLBplus out-out out-out QWS ADP Type3 Type1
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW4A Inactive DFGout BBAminus out-out none-none S5E Type3
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW4B Inactive DFGout BBAminus out-out none-none S5E Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUUA Inactive DFGout BBAminus out-out out-in W49 Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUUB Inactive DFGout BBAminus out-out out-out W49 Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUVA Inactive DFGout BBAminus out-out out-out W3R Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUVB Inactive DFGout BBAminus out-out out-out W3R Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OV7A Inactive DFGout BBAminus out-out out-out W3W Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OVZA Inactive DFGout BBAminus out-out out-out W3N Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OVZB Inactive DFGout BBAminus out-out out-out W3N Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OWGA Inactive DFGout BBAminus out-none out-none W40 Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OWGB Inactive DFGout BBAminus out-none out-in W40 Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OWGC Inactive DFGout BBAminus out-none none-out W40 Type3
TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OW3A Inactive DFGout BBAminus out-none none-in W40 Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1ZA Inactive DFGout BBAminus in-out out-in FQD FQM Allosteric Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PL4A Inactive DFGout BBAminus in-out out-in OO7 Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D20A Inactive DFGout None out-out out-in FQD FQG Allosteric Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSPA Inactive DFGout None in-out out-in L0P Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NPTA Inactive DFGout None out-out out-in KWY Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSSA Inactive DFGout None in-out out-in L0M Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1YA Inactive DFGout None out-out out-in FQJ Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMIA Inactive DFGout None in-out out-in 6UE Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMJA Inactive DFGout None in-in out-in 6UF Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMKA Inactive DFGout None in-out out-in 6UG Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMMA Inactive DFGout None in-out out-in 6UJ Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMLA Inactive DFGout None in-out out-in 6UH Type3
TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMNA Inactive DFGout None in-out out-in 6UK Type3
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4I4FA Inactive DFGout None out-out none-out 1BR Type3

Human and Non-human protein kinases in complex with Type3 ligands

Total number of genes: 27
Total number of chains: 289
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Total
DFGin BLAminus 0 0 0 5 0 0 0 3 1 6 15
DFGin BLAplus 0 0 0 0 0 0 0 0 2 0 2
DFGin ABAminus 0 0 0 0 0 0 0 0 0 0 0
DFGin BLBminus 0 0 0 28 0 0 0 0 1 0 29
DFGin BLBplus 0 0 0 0 0 0 63 0 68 0 131
DFGin BLBtrans 0 0 0 0 0 0 0 0 0 0 0
DFGin None 0 1 0 0 0 0 0 0 0 0 1
DFGinter BABtrans 0 0 0 0 0 0 0 0 0 0 0
DFGinter None 0 0 0 2 0 0 0 0 0 0 2
DFGout BBAminus 1 0 0 20 0 0 8 32 23 0 84
DFGout None 0 0 0 5 0 0 1 1 14 3 24
None None 0 0 0 1 0 0 0 0 0 0 1
Total - 1 1 0 61 0 0 72 36 109 9 289

Download as tsv


Organism Group Gene UniprotID Protein PDB Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActloopCT Ligand Type
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3F3UB Inactive DFGout BBAminus in-out none-in 1AW Type3
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3F3TA Inactive DFGout BBAminus in-in none-out 1AU 1AU Type3 Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3F3UA Inactive DFGout BBAminus in-in none-out 1AW 1AW Type3 Type1
Homo sapiens AGC AKT2 AKT2_HUMAN RAC-beta serine/threonine-protein kinase 8Q61A Inactive DFGout BBAminus out-out out-none K06 Type3
Homo sapiens CAMK CAMK1D KCC1D_HUMAN Calcium/calmodulin-dependent protein kinase type 1D 8BFMA Inactive DFGin None out-none none-none QI6 QI6 Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXFA Inactive DFGin BLBminus out-out out-out 2AN 2AN Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXZA Inactive DFGin BLBminus out-out out-out 2AN 2AN JWS Allosteric Type3 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXQA Inactive DFGin BLBminus out-out out-out 2AN 2AN 2AN Type1 Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY1A Inactive DFGin BLBminus out-out out-out SU9 2AN 2AN Type1 Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWEA Inactive DFGin BLBminus none-none none-none 7TH 7TH Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7SA0A Inactive DFGin BLBminus out-out out-out 8KQ 8KQ Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FOWA Inactive DFGin BLBminus out-out out-out 1QK 7TW Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP0A Inactive DFGin BLBminus out-out out-out RRC 7TW Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ7A Inactive DFGin BLBminus out-out out-out STU 2AN 2AN Type1 Type3 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RXOA Inactive DFGin BLBminus out-none out-out 80E Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S4TA Inactive DFGin BLBminus out-out out-out 88O Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S7AA Inactive DFGin BLBminus out-none out-out 8FI Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S84A Inactive DFGin BLBminus out-out out-out 8IL Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S85A Inactive DFGin BLBminus out-out out-out 8IQ Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S9XA Inactive DFGin BLBminus out-out out-out 8KF Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWFA Inactive DFGin BLBminus out-out out-out 7TW Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UG1A Inactive DFGin BLBminus out-out out-out N5R N5R Type3 Allosteric
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F6SA Inactive DFGout BBAminus in-in none-out 0SQ Type3
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F7JA Inactive DFGout BBAminus in-in none-out 0SU Type3
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F70A Inactive None None in-in none-out 0ST Type3
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QA4A Inactive DFGin BLAminus out-out in-in HRZ HRZ HRZ HRZ Allosteric Type1 Allosteric Type3
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAQA Inactive DFGin BLAminus out-out in-in HVQ HVQ Type3 Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH9A Inactive DFGinter None in-out none-out IRG 0OQ Allosteric Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EHVA Inactive DFGinter None in-none none-out 0SJ 0SJ IRG 0SJ Type3 Allosteric Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3IW8A Inactive DFGout BBAminus in-in none-out HIZ Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFBA Inactive DFGout BBAminus in-in none-out Z87 Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFCA Inactive DFGout BBAminus in-in none-out Z86 Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNVA Inactive DFGout BBAminus in-in out-out 437 Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3NNXA Inactive DFGout BBAminus in-in out-out EDD Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1W82A Inactive DFGout BBAminus in-in out-out L10 Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1WBVA Inactive DFGout BBAminus in-in out-out LI3 Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HV7A Inactive DFGout BBAminus in-in none-out 1AU Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2BAJA Inactive DFGout BBAminus in-in out-out 1PP Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3O8UA Inactive DFGout BBAminus in-in none-out BMU Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OBJA Inactive DFGout BBAminus in-out none-out BMU Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3K3IA Inactive DFGout BBAminus in-in none-out JZJ I46 I46 Type3 Allosteric Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 4EH8A Inactive DFGout None in-in none-out IRG 0OP 0OP Allosteric Type3 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3LFDA Inactive DFGout None in-in none-out Z85 Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1KV1A Inactive DFGout None in-in none-out BMU Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3O8TA Inactive DFGout None in-out none-out BMU Type3
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3OC1A Inactive DFGout None in-in none-out BMU Type3
Homo sapiens CMGC MAPK7 MK07_HUMAN Mitogen-activated protein kinase 7 4ZSLA Inactive DFGin BLAminus out-out in-in 4QZ Type3
Homo sapiens CMGC MAPK7 MK07_HUMAN Mitogen-activated protein kinase 7 4ZSJA Inactive DFGin BLAminus in-out in-in 4R0 Type3
Homo sapiens CMGC MAPK7 MK07_HUMAN Mitogen-activated protein kinase 7 4ZSGA Inactive DFGin BLAminus in-out in-in 4QX Type3
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9A Inactive DFGout None out-out none-out 4K7 Type3
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9B Inactive DFGout None out-out none-none 4K7 Type3
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9C Inactive DFGout None out-out none-none 4K7 Type3
Homo sapiens OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYA None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
Homo sapiens OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYB None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
Homo sapiens OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8A Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
Homo sapiens OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8B Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
Homo sapiens OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9A Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
Homo sapiens OTHER WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9B Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN3A Inactive DFGin BLBplus out-out out-out ATP 5Y0 Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN9A Inactive DFGin BLBplus out-out out-out ACP 2P7 Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3SLSA Inactive DFGin BLBplus out-out out-out ANP 77D Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3SLSB Inactive DFGin BLBplus out-out out-out ANP 77D Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B3MA Inactive DFGin BLBplus out-out out-out ANP SU5 Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B3MB Inactive DFGin BLBplus out-out out-out ANP SU5 Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B7RA Inactive DFGin BLBplus out-out out-out ANP T1K Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B7RB Inactive DFGin BLBplus out-out out-none ANP T1K Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B94A Inactive DFGin BLBplus out-out out-out ANP T3W Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B94B Inactive DFGin BLBplus out-out out-none ANP T3W Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B9LA Inactive DFGin BLBplus out-out out-none ANP T4N Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7B9LB Inactive DFGin BLBplus out-out out-none ANP T4N Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3ORNA Inactive DFGin BLBplus out-out out-out ANP 3OR Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3OS3A Inactive DFGin BLBplus out-out out-out ATP 3OS Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3WIGA Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DV3A Inactive DFGin BLBplus out-out out-out ATP MEK Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3MBLA Inactive DFGin BLBplus out-out out-out ADP LSG Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3PP1A Inactive DFGin BLBplus out-out out-out ATP IZG Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQBA Inactive DFGin BLBplus out-out out-out ATP LUG Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U80A Inactive DFGin BLBplus out-out out-out ANP 3EX Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 1S9JA Inactive DFGin BLBplus out-out out-out ATP BBM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3DY7A Inactive DFGin BLBplus out-out out-out ATP 1CX Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3E8NA Inactive DFGin BLBplus out-out out-out ATP VRA Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHA Inactive DFGin BLBplus out-out out-none ATP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHB Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3VVHC Inactive DFGin BLBplus out-out out-out ATP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4ARKA Inactive DFGin BLBplus out-out out-out ADP M3K Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4LMNA Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4MNEE Inactive DFGin BLBplus out-out out-out ACP 573 Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQGA Inactive DFGin BLBplus out-out out-out ADP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7UMBC Inactive DFGin BLBplus out-out out-out ANP U9F Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 6PP9B Inactive DFGin BLBplus out-out out-out ANP LCJ Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0VB Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0WB Inactive DFGin BLBplus out-out out-out ANP QOA Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0XB Inactive DFGin BLBplus out-out out-out ANP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0YB Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0ZB Inactive DFGin BLBplus out-out out-out ANP CHU Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8DGTB Inactive DFGin BLBplus out-out out-out AGS LCJ Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 6NYBB Inactive DFGin BLBplus out-out out-out ADP LCJ Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4MNEH Inactive DFGin BLBplus out-out out-out ACP 573 573 Type1 Type3 Allosteric
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7MFDB Inactive DFGin BLBplus out-out out-out CHU Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4AN2A Inactive DFGin BLBplus out-out out-out EUI ACP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4ANBA Inactive DFGin BLBplus out-out out-out YQY ACP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 2P55A Inactive DFGin BLBplus out-out out-out MRA ATP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U7ZA Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4U81A Inactive DFGin BLBplus out-out out-out 3EY ANP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V01A Inactive DFGin BLBplus out-out out-out 3V0 ATP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3V04A Inactive DFGin BLBplus out-out out-out V04 ATP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQCA Inactive DFGin BLBplus out-out out-out 3BM AGS Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQHA Inactive DFGin BLBplus out-out out-out 5BM ADP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0TB Inactive DFGin BLBplus out-out out-out 3EW ANP Type3 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 7M0UB Inactive DFGin BLBplus out-out out-out QO7 ANP Type3 Type1
Homo sapiens STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IA Inactive DFGin BLBplus out-out out-out ATP 5EA Type1 Type3
Homo sapiens STE MAP2K2 MP2K2_HUMAN Dual specificity mitogen-activated protein kinase kinase 2 1S9IB Inactive DFGin BLBplus out-out out-none ATP 5EA Type1 Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJIA Inactive DFGout BBAminus out-out out-in 4OQ Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJIB Inactive DFGout BBAminus out-out out-in 4OQ Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJIC Inactive DFGout BBAminus out-out out-out 4OQ Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJID Inactive DFGout BBAminus out-out in-out 4OQ Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJA Inactive DFGout BBAminus out-out out-in 4OR Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJB Inactive DFGout BBAminus out-out out-in 4OR Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJC Inactive DFGout BBAminus out-none none-out 4OR Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZJJD Inactive DFGout BBAminus out-none none-out 4OR Type3
Homo sapiens STE PAK1 PAK1_HUMAN Serine/threonine-protein kinase PAK 1 4ZLOA Inactive DFGout None out-out none-out 4PV Type3
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7LB Inactive DFGin BLAminus in-out in-in LU8 XHJ XHJ XHJ XHJ Type1 Allosteric Allosteric Allosteric Type3
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S83A Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 XJY Type1 Allosteric Allosteric Type3
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S9KB Inactive DFGin BLAminus in-out in-in LU8 YV4 Type1 Type3
Homo sapiens TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUA Inactive DFGout BBAminus out-out out-out RXN Type3
Homo sapiens TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUB Inactive DFGout BBAminus out-out out-out RXN Type3
Homo sapiens TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUC Inactive DFGout BBAminus out-none out-none RXN Type3
Homo sapiens TKL LIMK1 LIMK1_HUMAN LIM domain kinase 1 7ATUD Inactive DFGout BBAminus out-none out-out RXN Type3
Homo sapiens TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 4TPTA Inactive DFGout BBAminus out-out out-in 35H Type3
Homo sapiens TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 4TPTB Inactive DFGout BBAminus out-out out-in 35H Type3
Homo sapiens TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 5NXDB Inactive DFGout BBAminus out-out out-none 9D8 Type3
Homo sapiens TKL LIMK2 LIMK2_HUMAN LIM domain kinase 2 5NXDA Inactive DFGout None out-out out-none 9D8 Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C3EA Inactive DFGout BBAminus out-out out-out EJY Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITHA Inactive DFGout BBAminus out-out out-out RCM Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITHB Inactive DFGout BBAminus out-out out-out RCM Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITIA Inactive DFGout BBAminus out-out out-out 1HW Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 4ITIB Inactive DFGout BBAminus out-out out-out 1HW Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NYHA Inactive DFGout BBAminus out-out out-out L8D Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NYHB Inactive DFGout BBAminus out-out out-out L8D Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 7FCZA Inactive DFGout BBAminus out-out out-out 3IF Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 7FCZB Inactive DFGout BBAminus out-out out-out 3IF Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DA Inactive DFGout BBAminus out-out out-out EJP Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DB Inactive DFGout BBAminus out-out out-out EJP Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DC Inactive DFGout BBAminus out-out out-out EJP Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6C4DD Inactive DFGout BBAminus out-out out-out EJP Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 5HX6A Inactive DFGout BBAminus out-out out-out 65U Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 5TX5A Inactive DFGout BBAminus out-out out-out 7MJ Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6HHOA Inactive DFGout BBAminus out-out out-out G4W Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6HHOB Inactive DFGout BBAminus out-out out-none G4W Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6OCQB Inactive DFGout BBAminus out-out out-none M5J Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FA Inactive DFGout BBAminus out-out out-none JSW Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FB Inactive DFGout BBAminus out-out out-out JSW Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FC Inactive DFGout BBAminus out-out out-out JSW Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6R5FD Inactive DFGout BBAminus out-out out-out JSW Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6RLNA Inactive DFGout BBAminus out-out out-out K8K Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NW2A Inactive DFGout BBAminus out-out out-none L4Y Type3
Homo sapiens TKL RIPK1 RIPK1_HUMAN Receptor-interacting serine/threonine-protein kinase 1 6NW2B Inactive DFGout BBAminus out-out out-out L4Y Type3
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 3QRKA Inactive DFGout BBAminus in-in out-in 9DP Type3
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 7FEHA Inactive DFGout BBAminus in-in out-in 3UI Type3
Homo sapiens TYR DDR1 DDR1_HUMAN Epithelial discoidin domain-containing receptor 1 5BVKA Inactive DFGout None in-in out-in 4VC Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A27A Inactive DFGin BLAplus out-out none-out KY9 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2AA Inactive DFGin BLAplus out-out out-out KY9 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2DA Inactive DFGin BLBminus out-out none-in KXY Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1DB Inactive DFGin BLBplus out-out out-out ANP NQ1 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1LA Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1LC Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1LD Inactive DFGin BLBplus out-out none-out ANP 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QA Inactive DFGin BLBplus out-out out-in ANP O57 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QB Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QC Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P8QD Inactive DFGin BLBplus out-out out-in AMP O57 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6XL4A Inactive DFGin BLBplus out-out out-in Q6K NQ1 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6XL4D Inactive DFGin BLBplus out-out out-in ANP NQ1 Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5D41A Inactive DFGin BLBplus out-out none-in ANP 57N Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKA Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKB Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKC Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKD Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKE Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6DUKF Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKA Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKC Inactive DFGin BLBplus out-out out-in 8BS JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKD Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKE Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXKF Inactive DFGin BLBplus out-out none-in 8BS JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXMB Inactive DFGin BLBplus out-out none-in YY3 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXMD Inactive DFGin BLBplus out-out none-in ANP 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPA Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPB Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPD Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPF Inactive DFGin BLBplus out-out out-in ANP JBJ Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQB Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQD Inactive DFGin BLBplus out-out out-in ANP VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWA Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWB Inactive DFGin BLBplus out-out none-none YY3 VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWC Inactive DFGin BLBplus out-out out-in YY3 VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXWD Inactive DFGin BLBplus out-out none-out YY3 VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXA Inactive DFGin BLBplus out-out none-out ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXB Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXC Inactive DFGin BLBplus out-out none-in ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LTXD Inactive DFGin BLBplus out-out out-in ANP YFA Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6Z4BA Inactive DFGin BLBplus out-none out-out Q6K 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6Z4BB Inactive DFGin BLBplus out-out none-out Q6K 9LL Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6Z4DB Inactive DFGin BLBplus out-none none-out 8BS 57N Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1IA Inactive DFGin BLBplus out-out none-in ANP VNS Type1 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5ZWJA Inactive DFGin BLBplus out-none none-out 9LL Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2BA Inactive DFGin BLBplus out-out none-out KY9 Type3
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1DC Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6P1DD Inactive DFGin BLBplus out-out out-in NQ1 ANP Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 6XL4B Inactive DFGin BLBplus out-out none-in NQ1 Q6K Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPC Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXPE Inactive DFGin BLBplus out-out none-in JBJ YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQA Inactive DFGin BLBplus out-out out-out VNS ANP Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXQC Inactive DFGin BLBplus out-out out-in VNS ANP Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8A Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8C Inactive DFGin BLBplus out-out out-out VNS 8RC Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7LG8D Inactive DFGin BLBplus out-out none-out VNS 8RC Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7A2AA Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7A2AB Inactive DFGin BLBplus out-out none-out 57N 7G9 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HA Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HB Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HC Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HD Inactive DFGin BLBplus out-out out-out VNS YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HE Inactive DFGin BLBplus out-out none-in VNS YY3 Type3 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7K1HF Inactive DFGin BLBplus out-out none-out VNS YY3 Type3 Type1
Homo sapiens TYR EPHA3 EPHA3_HUMAN Ephrin type-A receptor 3 6IN0A Inactive DFGin BLAminus in-out in-in O4B O4B Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0A Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0B Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0C Inactive DFGout BBAminus in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3LW0D Inactive DFGout None in-out out-in CCX CCX Type3 Allosteric
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M0YA Inactive DFGin BLBplus out-out out-out M0Y M0Y Type1 Type3
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M14A Inactive DFGin BLBplus out-out out-out QWS QWS Type1 Type3
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M12A Inactive DFGin BLBplus out-out out-out 1YZ Type3
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M13A Inactive DFGin BLBplus out-out out-out 1E0 Type3
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M0ZA Inactive DFGin BLBplus out-out out-out M0Z M0Z Type3 Type1
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M15A Inactive DFGin BLBplus out-out out-out QWS ADP Type3 Type1
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW4A Inactive DFGout BBAminus out-out none-none S5E Type3
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW4B Inactive DFGout BBAminus out-out none-none S5E Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUUA Inactive DFGout BBAminus out-out out-in W49 Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUUB Inactive DFGout BBAminus out-out out-out W49 Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUVA Inactive DFGout BBAminus out-out out-out W3R Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OUVB Inactive DFGout BBAminus out-out out-out W3R Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OV7A Inactive DFGout BBAminus out-out out-out W3W Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OVZA Inactive DFGout BBAminus out-out out-out W3N Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OVZB Inactive DFGout BBAminus out-out out-out W3N Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OWGA Inactive DFGout BBAminus out-none out-none W40 Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OWGB Inactive DFGout BBAminus out-none out-in W40 Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OWGC Inactive DFGout BBAminus out-none none-out W40 Type3
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 8OW3A Inactive DFGout BBAminus out-none none-in W40 Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1ZA Inactive DFGout BBAminus in-out out-in FQD FQM Allosteric Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6PL4A Inactive DFGout BBAminus in-out out-in OO7 Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D20A Inactive DFGout None out-out out-in FQD FQG Allosteric Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSPA Inactive DFGout None in-out out-in L0P Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NPTA Inactive DFGout None out-out out-in KWY Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6NSSA Inactive DFGout None in-out out-in L0M Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 6D1YA Inactive DFGout None out-out out-in FQJ Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMIA Inactive DFGout None in-out out-in 6UE Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMJA Inactive DFGout None in-in out-in 6UF Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMKA Inactive DFGout None in-out out-in 6UG Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMMA Inactive DFGout None in-out out-in 6UJ Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMLA Inactive DFGout None in-out out-in 6UH Type3
Homo sapiens TYR NTRK1 NTRK1_HUMAN High affinity nerve growth factor receptor 5KMNA Inactive DFGout None in-out out-in 6UK Type3
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 4I4FA Inactive DFGout None out-out none-out 1BR Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8YA Inactive DFGin BLBminus in-in out-out SMV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8ZA Inactive DFGin BLBminus in-in out-out SN4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R97A Inactive DFGin BLBminus in-in out-out RUY Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9DA Inactive DFGin BLBminus in-in out-out N9J Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9EA Inactive DFGin BLBminus in-in none-out S7S Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9KA Inactive DFGin BLBminus in-in out-out SR4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9QA Inactive DFGin BLBminus in-in out-out LVD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9WA Inactive DFGin BLBminus in-in out-out STV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA1A Inactive DFGin BLBminus in-in out-out PO6 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA9A Inactive DFGin BLBminus in-in out-out SWD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P5KA Inactive DFGout BBAminus in-in none-out P5K Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P78A Inactive DFGout BBAminus in-in none-out P78 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P79A Inactive DFGout BBAminus in-in none-out P79 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7AA Inactive DFGout BBAminus in-in none-out P7A Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7BA Inactive DFGout BBAminus in-in none-out P7B Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7CA Inactive DFGout BBAminus in-in none-out P7C Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUTC Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUUC Inactive DFGin BLBplus out-out out-out ANP 4BM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUVC Inactive DFGin BLBplus out-out out-out ANP VKG Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUXC Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUYC Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUZC Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JV0C Inactive DFGin BLBplus out-out out-out ANP 4BM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JV1C Inactive DFGin BLBplus out-out out-out ANP VKG Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUSC Inactive DFGin BLBplus out-out out-out VKD ANP Type3 Type1

Non-Human protein kinases in complex with Type3 ligands

Total number of genes: 3
Total number of chains: 29
Spatial Label Dihedral Label AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Total
DFGin BLAminus 0 0 0 0 0 0 0 0 0 0 0
DFGin BLAplus 0 0 0 0 0 0 0 0 0 0 0
DFGin ABAminus 0 0 0 0 0 0 0 0 0 0 0
DFGin BLBminus 0 0 0 11 0 0 0 0 0 0 11
DFGin BLBplus 0 0 0 0 0 0 9 0 0 0 9
DFGin BLBtrans 0 0 0 0 0 0 0 0 0 0 0
DFGin None 0 0 0 0 0 0 0 0 0 0 0
DFGinter BABtrans 0 0 0 0 0 0 0 0 0 0 0
DFGinter None 0 0 0 0 0 0 0 0 0 0 0
DFGout BBAminus 0 0 0 6 0 0 0 0 3 0 9
DFGout None 0 0 0 0 0 0 0 0 0 0 0
None None 0 0 0 0 0 0 0 0 0 0 0
Total - 0 0 0 17 0 0 9 0 3 0 29

Download as tsv


Organism Group Gene UniprotID Protein PDB Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActloopCT Ligand Type
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3F3UB Inactive DFGout BBAminus in-out none-in 1AW Type3
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3F3TA Inactive DFGout BBAminus in-in none-out 1AU 1AU Type3 Type1
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3F3UA Inactive DFGout BBAminus in-in none-out 1AW 1AW Type3 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8YA Inactive DFGin BLBminus in-in out-out SMV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8ZA Inactive DFGin BLBminus in-in out-out SN4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R97A Inactive DFGin BLBminus in-in out-out RUY Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9DA Inactive DFGin BLBminus in-in out-out N9J Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9EA Inactive DFGin BLBminus in-in none-out S7S Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9KA Inactive DFGin BLBminus in-in out-out SR4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9QA Inactive DFGin BLBminus in-in out-out LVD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9WA Inactive DFGin BLBminus in-in out-out STV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA1A Inactive DFGin BLBminus in-in out-out PO6 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA9A Inactive DFGin BLBminus in-in out-out SWD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB Inactive DFGin BLBminus out-out out-out 87B ATP Type3 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P5KA Inactive DFGout BBAminus in-in none-out P5K Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P78A Inactive DFGout BBAminus in-in none-out P78 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P79A Inactive DFGout BBAminus in-in none-out P79 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7AA Inactive DFGout BBAminus in-in none-out P7A Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7BA Inactive DFGout BBAminus in-in none-out P7B Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P7CA Inactive DFGout BBAminus in-in none-out P7C Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUTC Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUUC Inactive DFGin BLBplus out-out out-out ANP 4BM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUVC Inactive DFGin BLBplus out-out out-out ANP VKG Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUXC Inactive DFGin BLBplus out-out out-out ANP QOM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUYC Inactive DFGin BLBplus out-out out-out ANP EUI Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUZC Inactive DFGin BLBplus out-out out-out ANP 3EW Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JV0C Inactive DFGin BLBplus out-out out-out ANP 4BM Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JV1C Inactive DFGin BLBplus out-out out-out ANP VKG Type1 Type3
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUSC Inactive DFGin BLBplus out-out out-out VKD ANP Type3 Type1