| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Active | DFGin | BLAminus | in-in | in-in | 2A2 BI4 | Allosteric Type1 | 74 - 359 | 9 |
| B | Active | DFGin | BLAminus | in-in | in-in | 2A2 BI4 | Allosteric Type1 | 73 - 359 | 8 |
| C | Active | DFGin | BLAminus | in-in | in-in | 2A2 BI4 | Allosteric Type1 | 74 - 359 | 9 |
| D | Active | DFGin | BLAminus | in-in | in-in | 2A2 BI4 | Allosteric Type1 | 73 - 359 | 8 |
Representative sequence - Chain D
53 63 73 83
gamdpefmdg taaeprpgag slqhaqpppQ PRKKRPEDFK
93 103 113 123
FGKILGEGSF STVVLARELA TSREYAIKIL EKRHIIKENK
133 143 153 163
VPYVTRERDV MSRLDHPFFV KLYFCFQDDE KLYFGLSYAK
173 183 193 203
NGELLKYIRK IGSFDETCTR FYTAEIVSAL EYLHGKGIIH
213 223 233 243
RDLKPENILL NEDMHIQITD FGTAKVLSpe skqaraNSFV
253 263 273 283
GTAQYVSPEL LTEKSACKSS DLWALGCIIY QLVAGLPPFR
293 303 313 323
AGNEYLIFQK IIKLEYDFPE KFFPKARDLV EKLLVLDATK
333 343 353
RLGCEEMEGY GPLKAHPFFE SVTWENLHQQ TPPKLT