Protein kinases in complex with ADP

Total number of genes: 44
Total number of chains: 191
Spatial Dihedral Chains Representative
DFGin BLAminus 151 6YZHA
DFGin ABAminus 5 3LCTA
DFGin BLBminus 2 2IJMB
DFGin BLBplus 17 4M15A
DFGin None 10 4RIYD
DFGinter None 3 5L8LA
None None 3 2W5AA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AGC CDC42BPB MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta 4UAKA 1.73 Active DFGin BLAminus in-in in-in ADP Type1
AGC PRKCI KPCI_HUMAN Protein kinase C iota type 5LIHA 3.25 Active DFGin BLAminus in-in in-in ADP Type1
AGC PRKCI KPCI_HUMAN Protein kinase C iota type 5LIHB 3.25 Active DFGin BLAminus in-in in-in ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8GUWA 2.7 Inactive DFGin ABAminus out-out in-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8GUWB 2.7 Inactive DFGin ABAminus out-out none-none ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8GUWC 2.7 Inactive DFGin ABAminus out-out none-none ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1MA 2.84 Inactive DFGin BLAminus in-in in-out T4X ADP Allosteric Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1DA 2.115 Inactive DFGin BLAminus in-in in-out T2F ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1GA 1.96 Inactive DFGin BLAminus in-in in-out T3I ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1HA 2.233 Inactive DFGin BLAminus in-in in-out T3U ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1KA 2.43 Inactive DFGin BLAminus in-in in-out T4O ADP T5L Allosteric Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 4BN1A 2.499 Inactive DFGin BLAminus in-in in-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 1MQ4A 1.9 Inactive DFGin BLAminus in-in in-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 1OL5A 2.5 Active DFGin BLAminus in-in in-in ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 1OL7A 2.75 Inactive DFGin BLAminus in-in in-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4DEEA 2.3 Inactive DFGin BLAminus in-in in-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5LXMA 2.08 Active DFGin BLAminus in-in in-in ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 4CEGA 2.1 Inactive DFGin BLAminus in-in in-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5G1XA 1.72 Active DFGin BLAminus in-in in-in ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORLA 1.69 Inactive DFGin BLAminus in-in in-out ADP A4W Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORNA 2.19 Inactive DFGin BLAminus in-in in-out ADP A5E Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OROA 2.12 Inactive DFGin BLAminus in-in in-out ADP A5H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORPA 2.19 Inactive DFGin BLAminus in-in in-out ADP A5K Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORRA 2.09 Inactive DFGin BLAminus in-in in-out ADP A5Q Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORSA 1.98 Inactive DFGin BLAminus in-in in-out ADP A5W Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORTA 2.56 Inactive DFGin BLAminus in-in in-out ADP A5Z Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORVA 1.88 Inactive DFGin BLAminus in-in in-out ADP A65 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORWA 2.0 Inactive DFGin BLAminus in-in in-out ADP A6E Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORXA 1.88 Inactive DFGin BLAminus in-in in-out ADP A6H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORYA 1.99 Inactive DFGin BLAminus in-in in-out ADP AY4 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORZA 1.92 Inactive DFGin BLAminus in-in in-out ADP A6W Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS0A 1.74 Inactive DFGin BLAminus in-in in-out ADP A6Z Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS1A 1.9 Inactive DFGin BLAminus in-in in-out ADP A7H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS2A 1.92 Inactive DFGin BLAminus in-in in-out ADP A7K Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS3A 1.81 Inactive DFGin BLAminus in-in in-out ADP A7N Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS4A 1.88 Inactive DFGin BLAminus in-in in-out ADP A8H Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS6A 2.2 Inactive DFGin BLAminus in-in in-out ADP A7Q Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSEA 1.9 Inactive DFGin BLAminus in-in in-out ADP A98 Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSFA 1.89 Inactive DFGin BLAminus in-in in-out ADP A9E Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSDA 1.99 Inactive DFGin BLAminus in-in in-out ADP A9B Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS5A 1.74 Inactive DFGin BLAminus in-in in-out ADP A8K Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R49A 2.209 Inactive DFGin BLAminus in-in in-out ADP JSB Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4AA 1.937 Inactive DFGin BLAminus in-in in-out ADP JRT Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4BA 2.15 Inactive DFGin BLAminus in-in in-out ADP JSN Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4CA 2.04 Inactive DFGin BLAminus in-in in-out ADP JRQ Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4DA 2.009 Inactive DFGin BLAminus in-in in-out ADP JRW Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 7ZTLA 1.9 Active DFGin BLAminus in-in in-in ADP BCN Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8OF5A 1.97 Inactive DFGin BLAminus in-in in-out ADP MPO Type1 Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C14A 1.93 Inactive DFGin BLAminus in-in in-out ADP T5L T0L Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C15A 2.41 Inactive DFGin BLAminus in-in in-out ADP T4C T5L Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1FA 1.924 Inactive DFGin BLAminus in-in in-out ADP T5L T2O Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1IA 2.81 Inactive DFGin BLAminus in-in in-out ADP T1L T5L Type1 Allosteric Allosteric
CAMK AURKA AURKA_HUMAN Aurora kinase A 5ODTA 2.021 Inactive DFGin None out-out out-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8JA 1.68 Inactive DFGinter None out-out none-none ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8KA 1.79 Inactive DFGinter None out-out out-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8LA 1.67 Inactive DFGinter None out-out out-out ADP Type1
CAMK AURKA AURKA_HUMAN Aurora kinase A 2WQEA 2.5 Inactive None None out-none none-out ADP ADP ADP Type1 Type1 Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJSA 2.75 Active DFGin BLAminus in-in in-in ADP Type1
CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJPA 2.56 Active DFGin BLAminus in-in in-in ADP Type1
CAMK CHEK2 CHK2_HUMAN Serine/threonine-protein kinase Chk2 2CN5A 2.25 Inactive DFGin BLAminus in-out in-out ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 2W4JA 1.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3EH9A 1.7 Active DFGin BLAminus in-in in-in ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3F5GA 1.85 Active DFGin BLAminus in-in in-in ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 2W4KA 1.9 Active DFGin BLAminus in-in in-in ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3GU6A 1.49 Active DFGin BLAminus in-in in-in ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3GU7A 1.9 Active DFGin BLAminus in-in in-in ADP Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 2XUUA 1.8 Active DFGin BLAminus in-in in-in ADP Type1
CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 1NY3A 3.0 None DFGin BLAminus out-out in-none ADP Type1
CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSA 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSB 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSC 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSD 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSE 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSF 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 6QF4A 2.495 Inactive DFGin BLAminus out-out in-out ADP Type1
CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7Q7CA 2.85 None DFGin BLAminus in-in in-none ADP Type1
CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU7A 2.08 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU7B 2.08 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8A 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8B 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8C 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8D 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
CK1 TTBK1 TTBK1_HUMAN Tau-tubulin kinase 1 4BTJA 2.16 Active DFGin BLAminus in-in in-in ADP Type1
CK1 TTBK2 TTBK2_HUMAN Tau-tubulin kinase 2 6VRFA 1.5 Active DFGin BLAminus in-in in-in ADP Type1
CK1 TTBK2 TTBK2_HUMAN Tau-tubulin kinase 2 6VRFB 1.5 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 4NSTA 2.2 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 4NSTC 2.2 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK13 CDK13_HUMAN Cyclin-dependent kinase 13 5EFQA 2.0 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK13 CDK13_HUMAN Cyclin-dependent kinase 13 5EFQC 2.0 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4I3ZA 2.05 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4I3ZC 2.05 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHRA 2.17 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHRC 2.17 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHWA 1.91 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHWC 1.91 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4II5A 2.15 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4II5C 2.15 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY0A 1.44 Active DFGin BLAminus in-in in-in KC0 ADP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AE7A 1.28 Active DFGin BLAminus in-in in-in LVU ADP Allosteric Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Z19B 1.47 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OQUB 2.324 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORKB 2.143 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7QUXA 1.48 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6YZHA 1.19 Active DFGin BLAminus in-in in-in ADP Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6YPNB 1.58 Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHA 1.848 Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHB 1.848 Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8A 1.92 Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8B 1.92 Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJB 1.99 Active DFGin BLAminus in-in in-in ADP A4Q Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORKA 2.143 Active DFGin BLAminus in-in in-in ADP A4T Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYKA 1.31 Active DFGin BLAminus in-in in-in ADP KEC Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MPJA 2.14 Active DFGin BLAminus in-in in-in ADP IHP J2P Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OQUA 2.324 Active DFGin BLAminus in-in in-in ADP A4B IHP Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSLA 1.95 Active DFGin BLAminus in-in in-in ADP A9K A9K Type1 Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEB 1.89 Active DFGin BLAminus in-in in-in ADP IHP OQC OQC Type1 Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJA 1.99 Active DFGin BLAminus in-in in-in ADP A4Q A4Q IHP Type1 Allosteric Allosteric Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEA 1.89 Active DFGin BLAminus in-in in-in ADP IHP OQC OQC OQC Type1 Allosteric Allosteric Allosteric Allosteric
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM5A 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM7A 2.3 Active DFGin BLAminus in-in in-in ADP Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM0A 2.5 Active DFGin BLAminus in-in in-in ADP Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM3A 2.1 Active DFGin BLAminus in-in in-in ADP Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 1J1CA 2.1 Active DFGin BLAminus in-in in-in ADP Type1
CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 1J1CB 2.1 Active DFGin BLAminus in-in in-in ADP Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5A 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5B 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5C 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5D 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
CMGC PRPF4B PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog 4IFCA 2.13 Active DFGin BLAminus in-in in-in ADP Type1
CMGC PRPF4B PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog 4IFCB 2.13 Active DFGin BLAminus in-in in-in ADP Type1
CMGC SRPK1 SRPK1_HUMAN SRSF protein kinase 1 1WBPA 2.4 Active DFGin BLAminus in-in in-in ADP Type1
NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5AA 1.55 Inactive None None out-out out-out ADP Type1
NEK NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 2WQNA 2.3 Inactive DFGin None out-out none-none ADP Type1
OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMA 2.202 Active DFGin BLAminus in-in in-out ADP Type1
OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMB 2.202 Active DFGin BLAminus in-in in-out ADP Type1
OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4R8QA 2.31 Active DFGin BLAminus in-in in-out ADP Type1
OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZA 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZB 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F99A 2.33 None DFGin BLAminus in-in in-none ADP Type1
OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AA 2.17 None DFGin BLAminus in-in in-none ADP Type1
OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AC 2.17 None DFGin BLAminus in-in in-none ADP Type1
OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA7A 1.67 Active DFGin BLAminus in-in in-in ADP Type1
OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA8A 1.79 Active DFGin BLAminus in-in in-in ADP BEF Type1 Allosteric
OTHER EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KA 2.6 None DFGin BLAminus in-in in-none ADP Type1
OTHER EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KB 2.6 None DFGin BLAminus in-in in-none ADP Type1
OTHER EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KC 2.6 Inactive DFGin BLAminus in-in in-out ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDA 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDB 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDC 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23A 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23B 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23C 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23D 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
OTHER PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SORA 3.96 Inactive DFGin BLBminus out-out out-out ADP Type1
OTHER RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAUC 2.6 Active DFGin BLAminus in-in in-none ADP Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQIA 1.9 Inactive DFGin BLBplus out-out out-out ADP Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3MBLA 2.6 Inactive DFGin BLBplus out-out out-out ADP LSG Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4ARKA 2.6 Inactive DFGin BLBplus out-out out-out ADP M3K Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQGA 2.5 Inactive DFGin BLBplus out-out out-out ADP 4BM Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 6NYBB 4.1 Inactive DFGin BLBplus out-out out-out ADP LCJ Type1 Type3
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQHA 2.0 Inactive DFGin BLBplus out-out out-out 5BM ADP Type3 Type1
STE PAK3 PAK3_HUMAN Serine/threonine-protein kinase PAK 3 6FD3A 1.52 Active DFGin BLAminus in-in in-in ADP Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7JA 1.5 Active DFGin BLAminus in-in in-in ADP Type1
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4O27B 3.185 Inactive DFGin None in-in in-in ADP Type1
STE TAOK3 TAOK3_HUMAN Serine/threonine-protein kinase TAO3 6BDNA 1.5 Active DFGin BLAminus in-in in-in ADP Type1
TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 3G2FA 2.35 Active DFGin BLAminus in-in in-in ADP Type1
TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 3G2FB 2.35 Active DFGin BLAminus in-in in-in ADP Type1
TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 6UNPB 2.3 Active DFGin BLAminus in-in in-in ADP Type1
TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 6UNPA 2.3 Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
TKL KSR2 KSR2_HUMAN Kinase suppressor of Ras 2 7JUQB 3.22 Inactive DFGin BLBplus out-none out-out ADP Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2IA 3.12 Active DFGin BLAminus in-in in-in ADP Type1
TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2IB 3.12 Active DFGin BLAminus in-in in-in ADP Type1
TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 3LCTA 2.1 Inactive DFGin ABAminus in-none out-out ADP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIWB 3.1 Inactive DFGin None in-in in-in ADP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIWD 3.1 Inactive DFGin None in-in in-in ADP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIXB 3.1 Inactive DFGin None in-in in-in ADP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIXD 3.1 Inactive DFGin None in-in in-in ADP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIYB 2.981 Inactive DFGin None in-in in-in ADP Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIYD 2.981 Inactive DFGin None in-in in-in ADP Type1
TYR EPHB1 EPHB1_HUMAN Ephrin type-B receptor 1 7KPMA 1.608 Inactive DFGin None in-in none-none ADP Type1
TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M15A 1.52 Inactive DFGin BLBplus out-out out-out QWS ADP Type3 Type1
TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 5KHWA 2.47 Inactive DFGin ABAminus in-in in-in ADP Type1
TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 6C7YA 2.499 Active DFGin BLAminus in-in in-in ADP Type1
TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 5KHWB 2.47 Active DFGin BLAminus in-in in-in ADP Type1
TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 1PKGA 2.9 Inactive DFGin BLAminus in-out in-in ADP Type1
TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 1PKGB 2.9 Active DFGin BLAminus in-in in-in ADP Type1
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 3BRBA 1.9 Inactive DFGin BLBplus out-out none-out ADP Type1
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 3BRBB 1.9 Inactive DFGin BLBplus out-out none-none ADP Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 2IJMB 2.187 Inactive DFGin BLBminus in-out none-out ADP Type1
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 1MP8A 1.6 Inactive None None in-in none-out ADP Type1
TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 4GVJA 2.03 Active DFGin BLAminus in-in in-in ADP Type1

Protein kinases in complex with ADP

Total number of genes: 70
Total number of chains: 293
Spatial Dihedral Chains Representative
DFGin BLAminus 226 6YZHA
DFGin ABAminus 11 3LCTA
DFGin BLBminus 3 2IJMB
DFGin BLBplus 31 4M15A
DFGin None 14 5GZAA
DFGinter None 3 5L8LA
None None 5 8EWYA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana TKL BRI1 BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 5LPBA 1.98 Active DFGin BLAminus in-in in-in ADP Type1
Arabidopsis thaliana TKL BRI1 BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 5LPZA 2.48 Active DFGin BLAminus in-in in-in ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDXA 2.23 None DFGin BLAminus in-out in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDXB 2.23 None DFGin BLAminus in-in in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDYA 2.28 None DFGin BLAminus in-out in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDYB 2.28 None DFGin BLAminus in-out in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDWA 1.926 None DFGin BLAminus in-none in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDWB 1.926 None DFGin BLAminus in-none in-none ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4ZA 1.84 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C50A 2.6 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C50B 2.6 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C51A 3.55 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C51B 3.55 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9A 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9B 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9C 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9D 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Candida glabrata CK1 HRR25 Q6FS46_CANGA non-specific serine/threonine protein kinase 4XH0A 1.99 None DFGin BLAminus in-none in-in ADP Type1
Candida glabrata CK1 HRR25 Q6FS46_CANGA non-specific serine/threonine protein kinase 4XHGA 2.15 None DFGin BLAminus in-none in-out ADP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6EM6A 1.64 Inactive DFGin BLAminus in-out in-in ADP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6EM7A 1.238 Active DFGin BLAminus in-in in-in ADP Type1
Cryptosporidium parvum CMGC CDK Q5CRJ8_CRYPI Cyclin-dependent kinase 2 homolog 3NIZA 2.4 Inactive DFGin BLAminus in-in in-out ADP Type1
Danio rerio CAMK PLK1 Q4KMI8_DANRE Serine/threonine-protein kinase PLK 3D5WA 2.6 Inactive DFGin BLAminus out-out in-in ADP Type1
Danio rerio OTHER POMK SG196_DANRE Protein O-mannose kinase 5GZAA 2.0 Inactive DFGin None none-none in-out ADP ZZ1 Type1 Allosteric
Drosophila melanogaster CAMK CAMKII KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain 5FG8A 1.955 Active DFGin BLAminus in-in in-in ADP Type1
Drosophila melanogaster CAMK CAMKII KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain 5HU3A 1.885 Active DFGin BLAminus in-in in-in ADP Type1
Drosophila melanogaster CAMK OBSCN OBSCN_DROME Obscurin 8AK3A 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Drosophila melanogaster OTHER BUBR1 A1Z6I7_DROME Bub1-related kinase 6JKMA 1.95 Active DFGin BLAminus in-in in-out ADP Type1
Eimeria tenella CAMK CDPK Q3HNM4_EIMTE Calmodulin-like domain protein kinase 4YSJA 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Eimeria tenella CAMK CDPK Q3HNM4_EIMTE Calmodulin-like domain protein kinase 4YSJB 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens AGC CDC42BPB MRCKB_HUMAN Serine/threonine-protein kinase MRCK beta 4UAKA 1.73 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens AGC PRKCI KPCI_HUMAN Protein kinase C iota type 5LIHA 3.25 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens AGC PRKCI KPCI_HUMAN Protein kinase C iota type 5LIHB 3.25 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8GUWA 2.7 Inactive DFGin ABAminus out-out in-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8GUWB 2.7 Inactive DFGin ABAminus out-out none-none ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8GUWC 2.7 Inactive DFGin ABAminus out-out none-none ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1MA 2.84 Inactive DFGin BLAminus in-in in-out T4X ADP Allosteric Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1DA 2.115 Inactive DFGin BLAminus in-in in-out T2F ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1GA 1.96 Inactive DFGin BLAminus in-in in-out T3I ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1HA 2.233 Inactive DFGin BLAminus in-in in-out T3U ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1KA 2.43 Inactive DFGin BLAminus in-in in-out T4O ADP T5L Allosteric Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4BN1A 2.499 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 1MQ4A 1.9 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 1OL5A 2.5 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 1OL7A 2.75 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4DEEA 2.3 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5LXMA 2.08 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 4CEGA 2.1 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5G1XA 1.72 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORLA 1.69 Inactive DFGin BLAminus in-in in-out ADP A4W Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORNA 2.19 Inactive DFGin BLAminus in-in in-out ADP A5E Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OROA 2.12 Inactive DFGin BLAminus in-in in-out ADP A5H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORPA 2.19 Inactive DFGin BLAminus in-in in-out ADP A5K Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORRA 2.09 Inactive DFGin BLAminus in-in in-out ADP A5Q Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORSA 1.98 Inactive DFGin BLAminus in-in in-out ADP A5W Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORTA 2.56 Inactive DFGin BLAminus in-in in-out ADP A5Z Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORVA 1.88 Inactive DFGin BLAminus in-in in-out ADP A65 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORWA 2.0 Inactive DFGin BLAminus in-in in-out ADP A6E Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORXA 1.88 Inactive DFGin BLAminus in-in in-out ADP A6H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORYA 1.99 Inactive DFGin BLAminus in-in in-out ADP AY4 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ORZA 1.92 Inactive DFGin BLAminus in-in in-out ADP A6W Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS0A 1.74 Inactive DFGin BLAminus in-in in-out ADP A6Z Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS1A 1.9 Inactive DFGin BLAminus in-in in-out ADP A7H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS2A 1.92 Inactive DFGin BLAminus in-in in-out ADP A7K Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS3A 1.81 Inactive DFGin BLAminus in-in in-out ADP A7N Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS4A 1.88 Inactive DFGin BLAminus in-in in-out ADP A8H Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS6A 2.2 Inactive DFGin BLAminus in-in in-out ADP A7Q Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSEA 1.9 Inactive DFGin BLAminus in-in in-out ADP A98 Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSFA 1.89 Inactive DFGin BLAminus in-in in-out ADP A9E Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OSDA 1.99 Inactive DFGin BLAminus in-in in-out ADP A9B Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5OS5A 1.74 Inactive DFGin BLAminus in-in in-out ADP A8K Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R49A 2.209 Inactive DFGin BLAminus in-in in-out ADP JSB Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4AA 1.937 Inactive DFGin BLAminus in-in in-out ADP JRT Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4BA 2.15 Inactive DFGin BLAminus in-in in-out ADP JSN Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4CA 2.04 Inactive DFGin BLAminus in-in in-out ADP JRQ Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 6R4DA 2.009 Inactive DFGin BLAminus in-in in-out ADP JRW Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 7ZTLA 1.9 Active DFGin BLAminus in-in in-in ADP BCN Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8OF5A 1.97 Inactive DFGin BLAminus in-in in-out ADP MPO Type1 Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C14A 1.93 Inactive DFGin BLAminus in-in in-out ADP T5L T0L Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C15A 2.41 Inactive DFGin BLAminus in-in in-out ADP T4C T5L Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1FA 1.924 Inactive DFGin BLAminus in-in in-out ADP T5L T2O Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 8C1IA 2.81 Inactive DFGin BLAminus in-in in-out ADP T1L T5L Type1 Allosteric Allosteric
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5ODTA 2.021 Inactive DFGin None out-out out-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8JA 1.68 Inactive DFGinter None out-out none-none ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8KA 1.79 Inactive DFGinter None out-out out-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 5L8LA 1.67 Inactive DFGinter None out-out out-out ADP Type1
Homo sapiens CAMK AURKA AURKA_HUMAN Aurora kinase A 2WQEA 2.5 Inactive None None out-none none-out ADP ADP ADP Type1 Type1 Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJSA 2.75 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK CAMK2A KCC2A_HUMAN Calcium/calmodulin-dependent protein kinase type II subunit alpha 7UJPA 2.56 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK CHEK2 CHK2_HUMAN Serine/threonine-protein kinase Chk2 2CN5A 2.25 Inactive DFGin BLAminus in-out in-out ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 2W4JA 1.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3EH9A 1.7 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3F5GA 1.85 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 2W4KA 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3GU6A 1.49 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3GU7A 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 2XUUA 1.8 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK MAPKAPK2 MAPK2_HUMAN MAP kinase-activated protein kinase 2 1NY3A 3.0 None DFGin BLAminus out-out in-none ADP Type1
Homo sapiens CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSA 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSB 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSC 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSD 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSE 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK PASK PASK_HUMAN PAS domain-containing serine/threonine-protein kinase 3DLSF 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 6QF4A 2.495 Inactive DFGin BLAminus out-out in-out ADP Type1
Homo sapiens CAMK STK17B ST17B_HUMAN Serine/threonine-protein kinase 17B 7Q7CA 2.85 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU7A 2.08 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Homo sapiens CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU7B 2.08 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Homo sapiens CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8A 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Homo sapiens CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8B 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Homo sapiens CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8C 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Homo sapiens CK1 CSNK1D KC1D_HUMAN Casein kinase I isoform delta 6RU8D 1.92 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Homo sapiens CK1 TTBK1 TTBK1_HUMAN Tau-tubulin kinase 1 4BTJA 2.16 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CK1 TTBK2 TTBK2_HUMAN Tau-tubulin kinase 2 6VRFA 1.5 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CK1 TTBK2 TTBK2_HUMAN Tau-tubulin kinase 2 6VRFB 1.5 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 4NSTA 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK12 CDK12_HUMAN Cyclin-dependent kinase 12 4NSTC 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK13 CDK13_HUMAN Cyclin-dependent kinase 13 5EFQA 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK13 CDK13_HUMAN Cyclin-dependent kinase 13 5EFQC 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4I3ZA 2.05 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4I3ZC 2.05 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHRA 2.17 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHRC 2.17 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHWA 1.91 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QHWC 1.91 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4II5A 2.15 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4II5C 2.15 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZY0A 1.44 Active DFGin BLAminus in-in in-in KC0 ADP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 8AE7A 1.28 Active DFGin BLAminus in-in in-in LVU ADP Allosteric Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Z19B 1.47 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OQUB 2.324 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORKB 2.143 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7QUXA 1.48 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6YZHA 1.19 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6YPNB 1.58 Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHA 1.848 Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5CVHB 1.848 Active DFGin BLAminus in-in in-in ADP IHP Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8A 1.92 Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MP8B 1.92 Active DFGin BLAminus in-in in-in ADP RKN Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJB 1.99 Active DFGin BLAminus in-in in-in ADP A4Q Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORKA 2.143 Active DFGin BLAminus in-in in-in ADP A4T Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 7ZYKA 1.31 Active DFGin BLAminus in-in in-in ADP KEC Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MPJA 2.14 Active DFGin BLAminus in-in in-in ADP IHP J2P Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OQUA 2.324 Active DFGin BLAminus in-in in-in ADP A4B IHP Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5OSLA 1.95 Active DFGin BLAminus in-in in-in ADP A9K A9K Type1 Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEB 1.89 Active DFGin BLAminus in-in in-in ADP IHP OQC OQC Type1 Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5ORJA 1.99 Active DFGin BLAminus in-in in-in ADP A4Q A4Q IHP Type1 Allosteric Allosteric Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 5MOEA 1.89 Active DFGin BLAminus in-in in-in ADP IHP OQC OQC OQC Type1 Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM5A 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM7A 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM0A 2.5 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 4NM3A 2.1 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 1J1CA 2.1 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC GSK3B GSK3B_HUMAN Glycogen synthase kinase-3 beta 1J1CB 2.1 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5A 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5B 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5C 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 4IZ5D 3.19 Inactive DFGin BLAminus in-out in-out ADP Type1
Homo sapiens CMGC PRPF4B PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog 4IFCA 2.13 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC PRPF4B PRP4B_HUMAN Serine/threonine-protein kinase PRP4 homolog 4IFCB 2.13 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CMGC SRPK1 SRPK1_HUMAN SRSF protein kinase 1 1WBPA 2.4 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 2W5AA 1.55 Inactive None None out-out out-out ADP Type1
Homo sapiens NEK NEK7 NEK7_HUMAN Serine/threonine-protein kinase Nek7 2WQNA 2.3 Inactive DFGin None out-out none-none ADP Type1
Homo sapiens OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMA 2.202 Active DFGin BLAminus in-in in-out ADP Type1
Homo sapiens OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMB 2.202 Active DFGin BLAminus in-in in-out ADP Type1
Homo sapiens OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4R8QA 2.31 Active DFGin BLAminus in-in in-out ADP Type1
Homo sapiens OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZA 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
Homo sapiens OTHER BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZB 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
Homo sapiens OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F99A 2.33 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AA 2.17 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AC 2.17 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA7A 1.67 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens OTHER CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA8A 1.79 Active DFGin BLAminus in-in in-in ADP BEF Type1 Allosteric
Homo sapiens OTHER EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KA 2.6 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens OTHER EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KB 2.6 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens OTHER EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KC 2.6 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDA 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDB 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDC 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23A 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23B 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23C 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23D 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens OTHER PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SORA 3.96 Inactive DFGin BLBminus out-out out-out ADP Type1
Homo sapiens OTHER RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAUC 2.6 Active DFGin BLAminus in-in in-none ADP Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQIA 1.9 Inactive DFGin BLBplus out-out out-out ADP Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3MBLA 2.6 Inactive DFGin BLBplus out-out out-out ADP LSG Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 4ARKA 2.6 Inactive DFGin BLBplus out-out out-out ADP M3K Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQGA 2.5 Inactive DFGin BLBplus out-out out-out ADP 4BM Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 6NYBB 4.1 Inactive DFGin BLBplus out-out out-out ADP LCJ Type1 Type3
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 3EQHA 2.0 Inactive DFGin BLBplus out-out out-out 5BM ADP Type3 Type1
Homo sapiens STE PAK3 PAK3_HUMAN Serine/threonine-protein kinase PAK 3 6FD3A 1.52 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3A7JA 1.5 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 4O27B 3.185 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens STE TAOK3 TAOK3_HUMAN Serine/threonine-protein kinase TAO3 6BDNA 1.5 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 3G2FA 2.35 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 3G2FB 2.35 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 6UNPB 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TKL BMPR2 BMPR2_HUMAN Bone morphogenetic protein receptor type-2 6UNPA 2.3 Active DFGin BLAminus in-in in-in ADP ADP Type1 Allosteric
Homo sapiens TKL KSR2 KSR2_HUMAN Kinase suppressor of Ras 2 7JUQB 3.22 Inactive DFGin BLBplus out-none out-out ADP Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2IA 3.12 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TYR ABL1 ABL1_HUMAN Tyrosine-protein kinase ABL1 2G2IB 3.12 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TYR ALK ALK_HUMAN ALK tyrosine kinase receptor 3LCTA 2.1 Inactive DFGin ABAminus in-none out-out ADP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIWB 3.1 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIWD 3.1 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIXB 3.1 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIXD 3.1 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIYB 2.981 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RIYD 2.981 Inactive DFGin None in-in in-in ADP Type1
Homo sapiens TYR EPHB1 EPHB1_HUMAN Ephrin type-B receptor 1 7KPMA 1.608 Inactive DFGin None in-in none-none ADP Type1
Homo sapiens TYR ITK ITK_HUMAN Tyrosine-protein kinase ITK/TSK 4M15A 1.52 Inactive DFGin BLBplus out-out out-out QWS ADP Type3 Type1
Homo sapiens TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 5KHWA 2.47 Inactive DFGin ABAminus in-in in-in ADP Type1
Homo sapiens TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 6C7YA 2.499 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TYR JAK1 JAK1_HUMAN Tyrosine-protein kinase JAK1 5KHWB 2.47 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 1PKGA 2.9 Inactive DFGin BLAminus in-out in-in ADP Type1
Homo sapiens TYR KIT KIT_HUMAN Mast/stem cell growth factor receptor Kit 1PKGB 2.9 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 3BRBA 1.9 Inactive DFGin BLBplus out-out none-out ADP Type1
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 3BRBB 1.9 Inactive DFGin BLBplus out-out none-none ADP Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 2IJMB 2.187 Inactive DFGin BLBminus in-out none-out ADP Type1
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 1MP8A 1.6 Inactive None None in-in none-out ADP Type1
Homo sapiens TYR TYK2 TYK2_HUMAN Non-receptor tyrosine-protein kinase TYK2 4GVJA 2.03 Active DFGin BLAminus in-in in-in ADP Type1
Miscanthus lutarioriparius TKL RIPK A0A811MS43_9POAL Protein kinase domain-containing protein 8HODA 1.95 Inactive DFGin BLBplus out-out none-out ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4NTTB 3.5 Inactive DFGin ABAminus in-none in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4O21A 1.95 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1L3RE 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DH5A 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 5JR7A 3.56 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 5JR7C 3.56 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 7UJXE 2.4 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 7V0GE 1.63 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IADA 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAFA 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAIA 1.55 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAKA 1.6 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAYA 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAZA 1.85 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IB0A 1.87 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IB1A 1.63 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IB3A 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4XW6A 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 6E21A 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1JBPE 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1RDQE 1.26 Active DFGin BLAminus in-in in-in ADP ATP Type1 Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4NTTA 3.5 Inactive DFGin None in-out in-in ADP Type1
Mus musculus CAMK CAMK2A KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II subunit alpha 7B57B 1.95 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus CK1 CSNK1D KC1D_MOUSE Casein kinase I isoform delta 5X17A 2.0 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Mus musculus CK1 CSNK1D KC1D_MOUSE Casein kinase I isoform delta 5X17B 2.0 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Mus musculus CMGC GSK3B GSK3B_MOUSE Glycogen synthase kinase-3 beta 4NU1A 2.5 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3A 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3B 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4A 3.0 Inactive DFGin BLBplus out-out out-in 31K ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5A 3.4 Inactive DFGin BLBplus out-out out-in 31L ADP PEU Allosteric Type1 Allosteric
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4B 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4C 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4D 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5B 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5C 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5D 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HENA 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HENB 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HENC 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HEND 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FA 3.6 Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FB 3.6 Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYA 5.5 Inactive None None in-none in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYB 5.5 Inactive None None in-none in-in ADN ADP Allosteric Type1
Mus musculus TYR SRC SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src 8XN8A 1.95 Inactive DFGin BLBplus out-out out-out ADP Type1
Mus musculus TYR SRC SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src 6F3FA 2.418 Inactive DFGin BLBplus out-out out-out ADP Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F61A 1.8 Inactive DFGin BLBminus in-out none-none ADP Type1
Mycobacterium tuberculosis OTHER PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 4Y0XA 1.74 Inactive DFGin BLAminus out-out in-in ADP Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUQC 3.22 Inactive DFGin BLBplus out-out out-out ADP Type1
Oryza sativa OTHER FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUVA 2.09 Inactive DFGin BLAminus in-in in-out ADP Type1
Pediculus humanus OTHER PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIA 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Pediculus humanus OTHER PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIB 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Rattus norvegicus AGC PRKACA KAPCA_RAT cAMP-dependent protein kinase catalytic subunit alpha 3TNQB 3.097 Inactive DFGin ABAminus in-in in-in ADP Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4GVAA 1.83 Inactive DFGin BLAminus out-out in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9HA 1.55 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9IA 2.5 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9JA 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9FA 1.8 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2F9GA 2.1 None DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae CMGC KIN28 KIN28_YEAST Serine/threonine-protein kinase KIN28 6XI8A 3.64 Inactive DFGin BLAminus in-out in-in ADP Type1
Saccharomyces cerevisiae CMGC KIN28 KIN28_YEAST Serine/threonine-protein kinase KIN28 7KUEA 3.5 Inactive DFGin BLAminus in-out in-in ADP Type1
Saccharomyces cerevisiae CMGC SKY1 SKY1_YEAST Serine/threonine-protein kinase SKY1 1Q8YA 2.05 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae OTHER BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW9A 1.951 Active DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae OTHER CDC7 CDC7_YEAST Cell division control protein 7 7PT78 3.8 Inactive DFGin ABAminus in-out in-in ADP BEF Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOA 2.4 None DFGin BLAminus out-in in-none ADP Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOB 2.4 None DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0A 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0B 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Schistosoma mansoni TYR VKR2 A0A3Q0KQ92_SCHMA Guanylate cyclase 7ZVSA 3.07 Inactive DFGin ABAminus in-out in-in ADP Type1
Schistosoma mansoni TYR VKR2 A0A3Q0KQ92_SCHMA Guanylate cyclase 7ZVSB 3.07 Inactive DFGin ABAminus in-in in-in ADP Type1
Serratia sp. OTHER PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1TA 1.55 Inactive DFGin ABAminus in-out out-out ADP Type1

Protein kinases in complex with ADP

Total number of genes: 34
Total number of chains: 102
Spatial Dihedral Chains Representative
DFGin BLAminus 75 6EM7A
DFGin ABAminus 6 3TNQB
DFGin BLBminus 1 3F61A
DFGin BLBplus 14 8XN8A
DFGin None 4 5GZAA
None None 2 8EWYA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana TKL BRI1 BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 5LPBA 1.98 Active DFGin BLAminus in-in in-in ADP Type1
Arabidopsis thaliana TKL BRI1 BRI1_ARATH Protein BRASSINOSTEROID INSENSITIVE 1 5LPZA 2.48 Active DFGin BLAminus in-in in-in ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDXA 2.23 None DFGin BLAminus in-out in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDXB 2.23 None DFGin BLAminus in-in in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDYA 2.28 None DFGin BLAminus in-out in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDYB 2.28 None DFGin BLAminus in-out in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDWA 1.926 None DFGin BLAminus in-none in-none ADP Type1
Arabidopsis thaliana TKL FERONIA FERON_ARATH Receptor-like protein kinase FERONIA 7XDWB 1.926 None DFGin BLAminus in-none in-none ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C4ZA 1.84 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C50A 2.6 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C50B 2.6 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C51A 3.55 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3C51B 3.55 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9A 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9B 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9C 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Bos taurus AGC GRK1 GRK1_BOVIN Rhodopsin kinase GRK1 3QC9D 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Candida glabrata CK1 HRR25 Q6FS46_CANGA non-specific serine/threonine protein kinase 4XH0A 1.99 None DFGin BLAminus in-none in-in ADP Type1
Candida glabrata CK1 HRR25 Q6FS46_CANGA non-specific serine/threonine protein kinase 4XHGA 2.15 None DFGin BLAminus in-none in-out ADP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6EM6A 1.64 Inactive DFGin BLAminus in-out in-in ADP Type1
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6EM7A 1.238 Active DFGin BLAminus in-in in-in ADP Type1
Cryptosporidium parvum CMGC CDK Q5CRJ8_CRYPI Cyclin-dependent kinase 2 homolog 3NIZA 2.4 Inactive DFGin BLAminus in-in in-out ADP Type1
Danio rerio CAMK PLK1 Q4KMI8_DANRE Serine/threonine-protein kinase PLK 3D5WA 2.6 Inactive DFGin BLAminus out-out in-in ADP Type1
Danio rerio OTHER POMK SG196_DANRE Protein O-mannose kinase 5GZAA 2.0 Inactive DFGin None none-none in-out ADP ZZ1 Type1 Allosteric
Drosophila melanogaster CAMK CAMKII KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain 5FG8A 1.955 Active DFGin BLAminus in-in in-in ADP Type1
Drosophila melanogaster CAMK CAMKII KCC2A_DROME Calcium/calmodulin-dependent protein kinase type II alpha chain 5HU3A 1.885 Active DFGin BLAminus in-in in-in ADP Type1
Drosophila melanogaster CAMK OBSCN OBSCN_DROME Obscurin 8AK3A 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Drosophila melanogaster OTHER BUBR1 A1Z6I7_DROME Bub1-related kinase 6JKMA 1.95 Active DFGin BLAminus in-in in-out ADP Type1
Eimeria tenella CAMK CDPK Q3HNM4_EIMTE Calmodulin-like domain protein kinase 4YSJA 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Eimeria tenella CAMK CDPK Q3HNM4_EIMTE Calmodulin-like domain protein kinase 4YSJB 2.7 Active DFGin BLAminus in-in in-in ADP Type1
Miscanthus lutarioriparius TKL RIPK A0A811MS43_9POAL Protein kinase domain-containing protein 8HODA 1.95 Inactive DFGin BLBplus out-out none-out ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4NTTB 3.5 Inactive DFGin ABAminus in-none in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4O21A 1.95 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1L3RE 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4DH5A 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 5JR7A 3.56 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 5JR7C 3.56 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 7UJXE 2.4 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 7V0GE 1.63 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IADA 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAFA 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAIA 1.55 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAKA 1.6 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAYA 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IAZA 1.85 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IB0A 1.87 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IB1A 1.63 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4IB3A 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4XW6A 1.9 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 6E21A 2.0 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1JBPE 2.2 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 1RDQE 1.26 Active DFGin BLAminus in-in in-in ADP ATP Type1 Type1
Mus musculus AGC PRKACA KAPCA_MOUSE cAMP-dependent protein kinase catalytic subunit alpha 4NTTA 3.5 Inactive DFGin None in-out in-in ADP Type1
Mus musculus CAMK CAMK2A KCC2A_MOUSE Calcium/calmodulin-dependent protein kinase type II subunit alpha 7B57B 1.95 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus CK1 CSNK1D KC1D_MOUSE Casein kinase I isoform delta 5X17A 2.0 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Mus musculus CK1 CSNK1D KC1D_MOUSE Casein kinase I isoform delta 5X17B 2.0 Active DFGin BLAminus in-in in-in ADP Type1.5_Back
Mus musculus CMGC GSK3B GSK3B_MOUSE Glycogen synthase kinase-3 beta 4NU1A 2.5 Active DFGin BLAminus in-in in-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3A 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3B 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4A 3.0 Inactive DFGin BLBplus out-out out-in 31K ADP Allosteric Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5A 3.4 Inactive DFGin BLBplus out-out out-in 31L ADP PEU Allosteric Type1 Allosteric
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4B 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4C 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4D 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5B 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5C 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus OTHER ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5D 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HENA 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HENB 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HENC 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR EPHB2 EPHB2_MOUSE Ephrin type-B receptor 2 2HEND 2.6 None DFGin BLAminus in-in none-none ADP Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FA 3.6 Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 7T6FB 3.6 Inactive DFGin None in-out in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYA 5.5 Inactive None None in-none in-in ADN ADP Allosteric Type1
Mus musculus TYR JAK1 JAK1_MOUSE Tyrosine-protein kinase JAK1 8EWYB 5.5 Inactive None None in-none in-in ADN ADP Allosteric Type1
Mus musculus TYR SRC SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src 8XN8A 1.95 Inactive DFGin BLBplus out-out out-out ADP Type1
Mus musculus TYR SRC SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src 6F3FA 2.418 Inactive DFGin BLBplus out-out out-out ADP Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F61A 1.8 Inactive DFGin BLBminus in-out none-none ADP Type1
Mycobacterium tuberculosis OTHER PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 4Y0XA 1.74 Inactive DFGin BLAminus out-out in-in ADP Type1
Oryctolagus cuniculus STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 7JUQC 3.22 Inactive DFGin BLBplus out-out out-out ADP Type1
Oryza sativa OTHER FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUVA 2.09 Inactive DFGin BLAminus in-in in-out ADP Type1
Pediculus humanus OTHER PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIA 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Pediculus humanus OTHER PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIB 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Rattus norvegicus AGC PRKACA KAPCA_RAT cAMP-dependent protein kinase catalytic subunit alpha 3TNQB 3.097 Inactive DFGin ABAminus in-in in-in ADP Type1
Rattus norvegicus CMGC MAPK1 MK01_RAT Mitogen-activated protein kinase 1 4GVAA 1.83 Inactive DFGin BLAminus out-out in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9HA 1.55 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9IA 2.5 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9JA 2.3 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2B9FA 1.8 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae CMGC FUS3 FUS3_YEAST Mitogen-activated protein kinase FUS3 2F9GA 2.1 None DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae CMGC KIN28 KIN28_YEAST Serine/threonine-protein kinase KIN28 6XI8A 3.64 Inactive DFGin BLAminus in-out in-in ADP Type1
Saccharomyces cerevisiae CMGC KIN28 KIN28_YEAST Serine/threonine-protein kinase KIN28 7KUEA 3.5 Inactive DFGin BLAminus in-out in-in ADP Type1
Saccharomyces cerevisiae CMGC SKY1 SKY1_YEAST Serine/threonine-protein kinase SKY1 1Q8YA 2.05 Active DFGin BLAminus in-in in-in ADP Type1
Saccharomyces cerevisiae OTHER BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW9A 1.951 Active DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae OTHER CDC7 CDC7_YEAST Cell division control protein 7 7PT78 3.8 Inactive DFGin ABAminus in-out in-in ADP BEF Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOA 2.4 None DFGin BLAminus out-in in-none ADP Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOB 2.4 None DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0A 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae OTHER IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0B 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Schistosoma mansoni TYR VKR2 A0A3Q0KQ92_SCHMA Guanylate cyclase 7ZVSA 3.07 Inactive DFGin ABAminus in-out in-in ADP Type1
Schistosoma mansoni TYR VKR2 A0A3Q0KQ92_SCHMA Guanylate cyclase 7ZVSB 3.07 Inactive DFGin ABAminus in-in in-in ADP Type1
Serratia sp. OTHER PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1TA 1.55 Inactive DFGin ABAminus in-out out-out ADP Type1