5Y80

GAK (Cyclin-G-associated kinase)
Group: OTHER
Uniprot: GAK_HUMAN
Organism: Homo sapiens
Domain boundary: 40 - 315
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric 25 - 332 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        32         42         52         62 
gSQSDFVGQT VELGELRLRV RRVLAEGGFA FVYEAQDVGS 
        72         82         92        102 
GREYALKRLL SNEEEKNRAI IQEVCFMKKL SGHPNIVQFC 
       112        122        132        142 
SAASIGKEES DTGQAEFLLL TELCKGQLVE FLKKMesrGP 
       152        162        172        182 
LSCDTVLKIF YQTCRAVQHM HRQKPPIIHR DLKVENLLLS 
       192        202        212        222 
NQGTIKLCDF GSATTISHYP DYSWSAQRRA LVEEEITRNT 
       232        242        252        262 
TPMYRTPEII DLYSNFPIGE KQDIWALGCI LYLLCFRQHP 
       272        282        292        302 
FEDGAKLRIV NGKYSIPPHD TQYTVFHSLI RAMLQVNPEE 
       312        322        332 
RLSIAEVVHQ LQEIAAARNV NPKSPITELL eqn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None