ABL2 (Tyrosine-protein kinase ABL2)

Group: TYR
Uniprot: ABL2_HUMAN
Domain boundary: 288 - 541


Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 4 AF-P42684-K1A
DFGinter None 1 3HMIA
DFGout BBAminus 1 3GVUA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-P42684-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 280 - 549 None None 0
2XYNA 2.81 None DFGin BLAminus in-none in-in VX6 Type1 280 - 545 None None 0
2XYNB 2.81 None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric 280 - 545 None None 0
2XYNC 2.81 None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric 281 - 544 None None 0
3HMIA 1.65 Inactive DFGinter None in-in out-in DKI Type1 279 - 546 None None 0
3GVUA 2.05 Inactive DFGout BBAminus in-in out-in STI STI Type2 Allosteric 279 - 546 None None 7

ABL2 (Tyrosine-protein kinase ABL2)

Group: TYR
Total number of chains: 8
Spatial Dihedral Chains Representative
DFGin BLAminus 6 AF-P42684-K1A
DFGinter None 1 3HMIA
DFGout BBAminus 1 3GVUA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens ABL2_HUMAN AF-P42684-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 280 - 549 None None 0
Homo sapiens ABL2_HUMAN 2XYNA 2.81 None DFGin BLAminus in-none in-in VX6 Type1 280 - 545 None None 0
Homo sapiens ABL2_HUMAN 2XYNB 2.81 None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric 280 - 545 None None 0
Homo sapiens ABL2_HUMAN 2XYNC 2.81 None DFGin BLAminus in-none in-in VX6 VX6 VX6 Type1 Allosteric Allosteric 281 - 544 None None 0
Homo sapiens ABL2_HUMAN 3HMIA 1.65 Inactive DFGinter None in-in out-in DKI Type1 279 - 546 None None 0
Homo sapiens ABL2_HUMAN 3GVUA 2.05 Inactive DFGout BBAminus in-in out-in STI STI Type2 Allosteric 279 - 546 None None 7
Mus musculus ABL2_MOUSE 4XLIA 2.5 Inactive DFGin BLAminus in-out in-in 1N1 Type1.5_Back 279 - 546 None None 0
Mus musculus ABL2_MOUSE 4XLIB 2.5 Active DFGin BLAminus in-in in-in 1N1 Type1.5_Back 279 - 546 None None 0

ABL2 (Tyrosine-protein kinase ABL2)

Group: TYR
Total number of chains: 2
Spatial Dihedral Chains Representative
DFGin BLAminus 2 4XLIA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Mus musculus ABL2_MOUSE 4XLIA 2.5 Inactive DFGin BLAminus in-out in-in 1N1 Type1.5_Back 279 - 546 None None 0
Mus musculus ABL2_MOUSE 4XLIB 2.5 Active DFGin BLAminus in-in in-in 1N1 Type1.5_Back 279 - 546 None None 0