DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)

Group: CMGC
Uniprot: DYR1A_HUMAN
Domain boundary: 159 - 479


Total number of chains: 215
Spatial Dihedral Chains Representative
DFGin BLAminus 212 AF-Q13627-K1A
DFGin ABAminus 2 6UIPB
DFGin None 1 6UIPA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
6UIPB 3.7 Inactive DFGin ABAminus in-in in-in Q8J Type1 136 - 478 None X321 0
6UIPC 3.7 Inactive DFGin ABAminus in-in none-in Q8J Type1 131 - 477 None X321 9
AF-Q13627-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 151 - 487 None None 0
6T6AD 2.8 Active DFGin BLAminus in-in in-in No_ligand No_ligand 135 - 481 None X321 0
6EILC 2.465 Active DFGin BLAminus in-in in-in No_ligand No_ligand 135 - 479 None X321 0
6LN1A 2.699 Active DFGin BLAminus in-in in-in EKU Type1 135 - 480 None X321 0
6LN1B 2.699 Active DFGin BLAminus in-in in-in EKU Type1 140 - 479 None X321 4
7A4RA 1.8 Active DFGin BLAminus in-in in-in QY8 Type1 148 - 479 None X321 0
7A4RB 1.8 Active DFGin BLAminus in-in in-in QY8 Type1 148 - 479 None X321 0
7A52A 2.1 Active DFGin BLAminus in-in in-in QYB Type1 148 - 479 None X321 0
7A52B 2.1 Active DFGin BLAminus in-in in-in QYB Type1 148 - 479 None X321 0
7AJMA 2.4 Active DFGin BLAminus in-in in-in RKW Type1 148 - 479 None X321 0
7AJMB 2.4 Active DFGin BLAminus in-in in-in RKW Type1 148 - 479 None X321 0
7AJSA 2.15 Active DFGin BLAminus in-in in-in RKH Type1 148 - 479 None X321 0
7AJSB 2.15 Active DFGin BLAminus in-in in-in RKH Type1 148 - 479 None X321 0
7OY6C 2.38 Active DFGin BLAminus in-in in-in 39I Type1 135 - 481 None X321 0
7A4SA 3.1 Active DFGin BLAminus in-in in-in QYE Type1 149 - 481 None X321 0
7A4ZA 1.9 Active DFGin BLAminus in-in in-in 6SD Type1 148 - 481 None X321 0
7A51A 1.9 Active DFGin BLAminus in-in in-in QYK Type1 148 - 481 None X321 0
7A53A 2.2 Active DFGin BLAminus in-in in-in QYZ Type1 148 - 481 None X321 0
7A53B 2.2 Active DFGin BLAminus in-in in-in QYZ Type1 148 - 481 None X321 0
7A5DA 1.8 Active DFGin BLAminus in-in in-in QYW Type1 148 - 481 None X321 0
7A5LA 2.1 Active DFGin BLAminus in-in in-in QZW Type1 148 - 481 None X321 0
7A5NA 2.3 Active DFGin BLAminus in-in in-in R05 Type1 148 - 481 None X321 0
7A5NB 2.3 Active DFGin BLAminus in-in in-in R05 Type1 148 - 481 None X321 0
7AJ2A 2.1 Active DFGin BLAminus in-in in-in RJ5 Type1 148 - 481 None X321 0
7AJ4A 2.0 Active DFGin BLAminus in-in in-in RHZ Type1 149 - 481 None X321 0
7AJ5A 2.0 Active DFGin BLAminus in-in in-in RHW Type1 149 - 481 None X321 0
7AJ7A 2.9 Active DFGin BLAminus in-in in-in RHT Type1 149 - 481 None X321 0
7AJ8A 2.0 Active DFGin BLAminus in-in in-in RJ8 Type1 148 - 481 None X321 0
7AJAA 2.2 Active DFGin BLAminus in-in in-in RJ2 Type1 148 - 481 None X321 0
7AJVA 2.1 Active DFGin BLAminus in-in in-in RKK Type1 148 - 481 None X321 0
7AJVB 2.1 Active DFGin BLAminus in-in in-in RKK Type1 148 - 481 None X321 0
7AJWA 2.8 Active DFGin BLAminus in-in in-in RKQ Type1 149 - 481 None X321 0
7AJYA 2.2 Active DFGin BLAminus in-in in-in RKZ Type1 148 - 481 None X321 0
7AJYB 2.2 Active DFGin BLAminus in-in in-in RKZ Type1 148 - 481 None X321 0
7AK2A 2.1 Active DFGin BLAminus in-in in-in RHH Type1 148 - 481 None X321 0
7AK2B 2.1 Active DFGin BLAminus in-in in-in RHH Type1 148 - 481 None X321 0
7AKAA 1.9 Active DFGin BLAminus in-in in-in RK2 Type1 148 - 481 None X321 0
7AKAB 1.9 Active DFGin BLAminus in-in in-in RK2 Type1 148 - 481 None X321 0
7AKBA 2.8 Active DFGin BLAminus in-in in-in RJZ Type1 148 - 481 None X321 0
7AKBB 2.8 Active DFGin BLAminus in-in in-in RJZ Type1 148 - 481 None X321 0
7AKEA 2.3 Active DFGin BLAminus in-in in-in RK8 Type1 148 - 481 None X321 0
7AKEB 2.3 Active DFGin BLAminus in-in in-in RK8 Type1 148 - 481 None X321 0
7AKLA 2.0 Active DFGin BLAminus in-in in-in RK5 Type1 148 - 481 None X321 0
6A1FA 1.5 Active DFGin BLAminus in-in in-in 9OF Type1 134 - 483 None X321 0
6A1GA 2.15 Active DFGin BLAminus in-in in-in 9OL Type1 134 - 480 None X321 0
6A1GB 2.15 Active DFGin BLAminus in-in in-in 9OL Type1 135 - 480 None X321 0
4MQ1A 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 480 None X321 0
4MQ1B 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 480 None X321 0
4MQ1C 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 479 None X321 0
4MQ1D 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 479 None X321 0
4MQ2A 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 136 - 481 None X321 0
4MQ2B 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 135 - 480 None X321 0
4MQ2C 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 135 - 480 None X321 0
4MQ2D 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 135 - 480 None X321 0
4YLJA 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 135 - 481 None X321 0
4YLJB 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 134 - 481 None X321 0
4YLJC 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 135 - 481 None X321 0
4YLJD 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 134 - 481 None X321 0
4YLKA 1.4 Active DFGin BLAminus in-in in-in 4E2 Type1 134 - 481 None X321 0
4YLLA 1.4 Active DFGin BLAminus in-in in-in 4E3 Type1 134 - 481 None X321 0
4YU2A 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 134 - 482 None X321 0
4YU2B 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 134 - 481 None X321 0
4YU2C 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 135 - 481 None X321 0
4YU2D 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 135 - 481 None X321 0
6QU2A 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
6QU2B 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
6QU2C 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
6QU2D 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
6S11A 2.445 Active DFGin BLAminus in-in in-in KQE Type1 134 - 480 None X321 0
6S11B 2.445 Active DFGin BLAminus in-in in-in KQE Type1 136 - 480 None X321 3
6S14A 1.05 Active DFGin BLAminus in-in in-in KQW Type1 135 - 481 None X321 0
6S17A 1.1 Active DFGin BLAminus in-in in-in KQK Type1 134 - 482 None X321 0
6S1BA 1.3 Active DFGin BLAminus in-in in-in KRQ Type1 135 - 481 None X321 0
6S1HA 1.05 Active DFGin BLAminus in-in in-in KQZ Type1 135 - 480 None X321 0
6S1IA 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 0
6S1IB 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 0
6S1IC 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 1
6S1ID 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 1
6S1JA 1.408 Active DFGin BLAminus in-in in-in KRK Type1 134 - 480 None X321 0
6T6AA 2.8 Active DFGin BLAminus in-in in-in MLW Type1 135 - 481 None X321 0
6T6AB 2.8 Active DFGin BLAminus in-in in-in MLW Type1 135 - 481 None X321 0
6T6AC 2.8 Active DFGin BLAminus in-in in-in MLW Type1 135 - 481 None X321 0
6UWYA 2.95 Active DFGin BLAminus in-in in-in QKG Type1 135 - 481 None X321 0
6UWYB 2.95 Active DFGin BLAminus in-in in-in QKG Type1 134 - 481 None X321 0
6UWYC 2.95 Active DFGin BLAminus in-in in-in QKG Type1 135 - 481 None X321 0
6UWYD 2.95 Active DFGin BLAminus in-in in-in QKG Type1 134 - 481 None X321 0
7FHSA 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 481 None X321 0
7FHSB 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 481 None X321 0
7FHSC 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 480 None X321 0
7FHSD 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 480 None X321 0
7FHTA 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 481 None X321 0
7FHTB 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 480 None X321 0
7FHTC 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 480 None X321 0
7FHTD 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 480 None X321 0
3ANQA 2.6 Active DFGin BLAminus in-in in-in EHB Type1 134 - 481 None X321 0
3ANQB 2.6 Active DFGin BLAminus in-in in-in EHB Type1 133 - 481 None X321 0
3ANQC 2.6 Active DFGin BLAminus in-in in-in EHB Type1 134 - 481 None X321 0
3ANQD 2.6 Active DFGin BLAminus in-in in-in EHB Type1 136 - 479 None X321 0
3ANRA 2.6 Active DFGin BLAminus in-in in-in HRM Type1 134 - 481 None X321 0
3ANRB 2.6 Active DFGin BLAminus in-in in-in HRM Type1 133 - 481 None X321 0
3ANRC 2.6 Active DFGin BLAminus in-in in-in HRM Type1 134 - 481 None X321 0
3ANRD 2.6 Active DFGin BLAminus in-in in-in HRM Type1 134 - 479 None X321 0
4NCTA 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 480 None X321 0
4NCTB 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 133 - 480 None X321 0
4NCTC 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 479 None X301,X321 0
4NCTD 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 480 None X321 0
5A3XA 2.26 Active DFGin BLAminus in-in in-in QIV Type1 134 - 481 None X321 0
5A3XB 2.26 Active DFGin BLAminus in-in in-in QIV Type1 133 - 481 None X321 0
5A3XC 2.26 Active DFGin BLAminus in-in in-in QIV Type1 134 - 481 None X321 0
5A3XD 2.26 Active DFGin BLAminus in-in in-in QIV Type1 134 - 480 None X321 0
5A4EA 2.68 Active DFGin BLAminus in-in in-in 7QQ Type1 134 - 480 None X321 0
5A4EB 2.68 Active DFGin BLAminus in-in in-in 7QQ Type1 133 - 480 None X321 0
5A4EC 2.68 Inactive DFGin BLAminus in-out in-in 7QQ Type1 134 - 473 None X321 0
5A4ED 2.68 Active DFGin BLAminus in-in in-in 7QQ Type1 134 - 480 None X321 0
5A4LA 2.73 Active DFGin BLAminus in-in in-in ZC3 Type1 134 - 480 None X321 0
5A4LB 2.73 Active DFGin BLAminus in-in in-in ZC3 Type1 133 - 480 None X321 0
5A4LC 2.73 Inactive DFGin BLAminus in-in out-in ZC3 Type1 135 - 479 None X321 0
5A4LD 2.73 Active DFGin BLAminus in-in in-in ZC3 Type1 134 - 479 None X321 0
5A4QA 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 134 - 480 None X321 0
5A4QB 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 133 - 480 None X321 0
5A4QC 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 135 - 479 None X321 0
5A4QD 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 134 - 479 None X321 0
5A4TA 2.15 Active DFGin BLAminus in-in in-in AJG Type1 134 - 480 None X321 0
5A4TB 2.15 Active DFGin BLAminus in-in in-in AJG Type1 133 - 480 None X321 0
5A4TC 2.15 Active DFGin BLAminus in-in in-in AJG Type1 135 - 479 None X321 0
5A4TD 2.15 Active DFGin BLAminus in-in in-in AJG Type1 134 - 479 None X321 0
5A54A 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 134 - 480 None X321 0
5A54B 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 133 - 480 None X321 0
5A54C 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 135 - 479 None X321 0
5A54D 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 134 - 479 None X321 0
6EIFA 2.22 Active DFGin BLAminus in-in in-in B5T Type1 134 - 480 None X321 0
6EIFB 2.22 Active DFGin BLAminus in-in in-in B5T Type1 133 - 480 None X321 0
6EIFC 2.22 Active DFGin BLAminus in-in in-in B5T Type1 135 - 479 None X321 0
6EIFD 2.22 Active DFGin BLAminus in-in in-in B5T Type1 134 - 479 None X321 0
6EIJA 2.42 Inactive DFGin BLAminus in-out in-in B5Z Type1 134 - 480 None X321 0
6EIJB 2.42 Active DFGin BLAminus in-in in-in B5Z Type1 133 - 480 None X321 0
6EIJD 2.42 Active DFGin BLAminus in-in in-in B5Z Type1 134 - 479 None X321 0
6EILA 2.465 Active DFGin BLAminus in-in in-in B6B Type1 134 - 480 None X321 0
6EILB 2.465 Active DFGin BLAminus in-in in-in B6B Type1 133 - 480 None X321 0
6EILD 2.465 Active DFGin BLAminus in-in in-in B6B Type1 134 - 479 None X321 0
6EIPA 2.56 Inactive DFGin BLAminus in-out in-in B7B Type1 134 - 480 None X321 0
6EIPB 2.56 Active DFGin BLAminus in-in in-in B7B Type1 133 - 480 None X321 0
6EIPC 2.56 Active DFGin BLAminus in-in in-in B7B Type1 135 - 479 None X321 0
6EIPD 2.56 Active DFGin BLAminus in-in in-in B7B Type1 134 - 479 None X321 0
6EIQA 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 134 - 480 None X321 0
6EIQB 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 133 - 480 None X321 0
6EIQC 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 135 - 479 None X321 0
6EIQD 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 134 - 479 None X321 0
6EIRA 2.4 Active DFGin BLAminus in-in in-in B6H Type1 134 - 480 None X321 0
6EIRB 2.4 Active DFGin BLAminus in-in in-in B6H Type1 133 - 480 None X321 0
6EIRC 2.4 Active DFGin BLAminus in-in in-in B6H Type1 135 - 479 None X321 0
6EIRD 2.4 Active DFGin BLAminus in-in in-in B6H Type1 134 - 479 None X321 0
6EISA 2.36 Active DFGin BLAminus in-in in-in B6N Type1 134 - 480 None X321 0
6EISB 2.36 Active DFGin BLAminus in-in in-in B6N Type1 133 - 480 None X321 0
6EISC 2.36 Active DFGin BLAminus in-in in-in B6N Type1 135 - 479 None X321 0
6EISD 2.36 Active DFGin BLAminus in-in in-in B6N Type1 134 - 479 None X321 0
6EIVA 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 134 - 480 None X321 0
6EIVB 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 133 - 480 None X321 0
6EIVC 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 135 - 479 None X321 0
6EIVD 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 134 - 479 None X321 0
6EJ4A 2.88 Inactive DFGin BLAminus in-out in-in B7W Type1 134 - 480 None X321 0
6EJ4B 2.88 Active DFGin BLAminus in-in in-in B7W Type1 133 - 480 None X321 0
6EJ4C 2.88 Active DFGin BLAminus in-in in-in B7W Type1 135 - 479 None X321 0
6EJ4D 2.88 Active DFGin BLAminus in-in in-in B7W Type1 134 - 479 None X321 0
6YF8A 3.198 Active DFGin BLAminus in-in in-in OPW Type1 134 - 480 None X321 0
6YF8B 3.198 Active DFGin BLAminus in-in in-in OPW Type1 133 - 480 None X321 0
6YF8C 3.198 Active DFGin BLAminus in-in in-in OPW Type1 135 - 479 None X321 0
6YF8D 3.198 Active DFGin BLAminus in-in in-in OPW Type1 134 - 479 None X321 0
7Z5NA 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
7Z5NB 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
7Z5NC 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 134 - 480 None X321 0
7Z5ND 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
7Z5NE 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
7Z5NF 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
7Z5NG 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 137 - 480 None X321 0
7Z5NH 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 4
8C3RA 2.06 Active DFGin BLAminus in-in in-in R7O Type1 135 - 480 None X321 0
8C3RB 2.06 Active DFGin BLAminus in-in in-in R7O Type1 136 - 480 None X321 0
8C3GA 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
8C3GB 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
8C3GC 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
8C3GD 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
2VX3A 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 481 None X321 0
2VX3B 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 480 None X321 0
2VX3C 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 480 None X321 0
2VX3D 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 480 None X321 0
2WO6A 2.5 Active DFGin BLAminus in-in in-in D15 Type1 133 - 481 None X321 0
2WO6B 2.5 Active DFGin BLAminus in-in in-in D15 Type1 136 - 480 None X321 0
4AZEA 3.15 Active DFGin BLAminus in-in in-in 3RA Type1 132 - 481 None X301,X321 0
4AZEB 3.15 Active DFGin BLAminus in-in in-in 3RA Type1 135 - 481 None X301,X321 0
4AZEC 3.15 Active DFGin BLAminus in-in in-in 3RA Type1 132 - 481 None X301,X321 0
5AIKA 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 481 None X321 0
5AIKB 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 481 None X321 0
5AIKC 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 481 None X321 0
5AIKD 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 480 None X321 0
7A4OA 1.9 Active DFGin BLAminus in-in in-in ANP Type1 136 - 481 None X321 0
7A4OB 1.9 Active DFGin BLAminus in-in in-in ANP Type1 134 - 481 None X321 0
7A4WA 2.7 Active DFGin BLAminus in-in in-in QYH Type1 136 - 481 None X321 0
7A4WB 2.7 Active DFGin BLAminus in-in in-in QYH Type1 134 - 481 None X321 0
7A55A 2.2 Active DFGin BLAminus in-in in-in QZ2 Type1 136 - 481 None X321 0
7A55B 2.2 Active DFGin BLAminus in-in in-in QZ2 Type1 134 - 481 None X321 0
7A5BA 2.6 Active DFGin BLAminus in-in in-in MFR Type1 136 - 481 None X321 0
7A5BB 2.6 Active DFGin BLAminus in-in in-in MFR Type1 134 - 481 None X321 0
7O7KA 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric 134 - 480 None X321 0
7O7KB 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric 133 - 480 None X321 0
7ZH8A 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 135 - 482 None X321 0
7ZH8B 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 135 - 481 None X321 0
7ZH8C 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 136 - 481 None X321 0
7ZH8D 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 135 - 480 None X321 0
8C3QA 2.32 Active DFGin BLAminus in-in in-in RUT Type1.5_Back 134 - 480 None X321 0
8C3QB 2.32 Active DFGin BLAminus in-in in-in RUT Type1.5_Back 136 - 480 None X321 0
6EIJC 2.42 Active DFGin BLAminus in-in in-in B5Z Type1.5_Front 135 - 479 None X321 0
6UIPA 3.7 Inactive DFGin None in-in in-in Q8J Type1 131 - 479 None X321 0

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)

Group: CMGC
Total number of chains: 215
Spatial Dihedral Chains Representative
DFGin BLAminus 212 AF-Q13627-K1A
DFGin ABAminus 2 6UIPB
DFGin None 1 6UIPA
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens DYR1A_HUMAN 6UIPB 3.7 Inactive DFGin ABAminus in-in in-in Q8J Type1 136 - 478 None X321 0
Homo sapiens DYR1A_HUMAN 6UIPC 3.7 Inactive DFGin ABAminus in-in none-in Q8J Type1 131 - 477 None X321 9
Homo sapiens DYR1A_HUMAN AF-Q13627-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 151 - 487 None None 0
Homo sapiens DYR1A_HUMAN 6T6AD 2.8 Active DFGin BLAminus in-in in-in No_ligand No_ligand 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6EILC 2.465 Active DFGin BLAminus in-in in-in No_ligand No_ligand 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6LN1A 2.699 Active DFGin BLAminus in-in in-in EKU Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6LN1B 2.699 Active DFGin BLAminus in-in in-in EKU Type1 140 - 479 None X321 4
Homo sapiens DYR1A_HUMAN 7A4RA 1.8 Active DFGin BLAminus in-in in-in QY8 Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7A4RB 1.8 Active DFGin BLAminus in-in in-in QY8 Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7A52A 2.1 Active DFGin BLAminus in-in in-in QYB Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7A52B 2.1 Active DFGin BLAminus in-in in-in QYB Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7AJMA 2.4 Active DFGin BLAminus in-in in-in RKW Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7AJMB 2.4 Active DFGin BLAminus in-in in-in RKW Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7AJSA 2.15 Active DFGin BLAminus in-in in-in RKH Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7AJSB 2.15 Active DFGin BLAminus in-in in-in RKH Type1 148 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7OY6C 2.38 Active DFGin BLAminus in-in in-in 39I Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A4SA 3.1 Active DFGin BLAminus in-in in-in QYE Type1 149 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A4ZA 1.9 Active DFGin BLAminus in-in in-in 6SD Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A51A 1.9 Active DFGin BLAminus in-in in-in QYK Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A53A 2.2 Active DFGin BLAminus in-in in-in QYZ Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A53B 2.2 Active DFGin BLAminus in-in in-in QYZ Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A5DA 1.8 Active DFGin BLAminus in-in in-in QYW Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A5LA 2.1 Active DFGin BLAminus in-in in-in QZW Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A5NA 2.3 Active DFGin BLAminus in-in in-in R05 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A5NB 2.3 Active DFGin BLAminus in-in in-in R05 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJ2A 2.1 Active DFGin BLAminus in-in in-in RJ5 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJ4A 2.0 Active DFGin BLAminus in-in in-in RHZ Type1 149 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJ5A 2.0 Active DFGin BLAminus in-in in-in RHW Type1 149 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJ7A 2.9 Active DFGin BLAminus in-in in-in RHT Type1 149 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJ8A 2.0 Active DFGin BLAminus in-in in-in RJ8 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJAA 2.2 Active DFGin BLAminus in-in in-in RJ2 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJVA 2.1 Active DFGin BLAminus in-in in-in RKK Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJVB 2.1 Active DFGin BLAminus in-in in-in RKK Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJWA 2.8 Active DFGin BLAminus in-in in-in RKQ Type1 149 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJYA 2.2 Active DFGin BLAminus in-in in-in RKZ Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AJYB 2.2 Active DFGin BLAminus in-in in-in RKZ Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AK2A 2.1 Active DFGin BLAminus in-in in-in RHH Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AK2B 2.1 Active DFGin BLAminus in-in in-in RHH Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKAA 1.9 Active DFGin BLAminus in-in in-in RK2 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKAB 1.9 Active DFGin BLAminus in-in in-in RK2 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKBA 2.8 Active DFGin BLAminus in-in in-in RJZ Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKBB 2.8 Active DFGin BLAminus in-in in-in RJZ Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKEA 2.3 Active DFGin BLAminus in-in in-in RK8 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKEB 2.3 Active DFGin BLAminus in-in in-in RK8 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7AKLA 2.0 Active DFGin BLAminus in-in in-in RK5 Type1 148 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6A1FA 1.5 Active DFGin BLAminus in-in in-in 9OF Type1 134 - 483 None X321 0
Homo sapiens DYR1A_HUMAN 6A1GA 2.15 Active DFGin BLAminus in-in in-in 9OL Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6A1GB 2.15 Active DFGin BLAminus in-in in-in 9OL Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ1A 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ1B 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ1C 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ1D 2.35 Active DFGin BLAminus in-in in-in 2C3 Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ2A 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 136 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ2B 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ2C 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4MQ2D 2.8 Active DFGin BLAminus in-in in-in 2C4 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4YLJA 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YLJB 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YLJC 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YLJD 2.58 Active DFGin BLAminus in-in in-in 4E1 Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YLKA 1.4 Active DFGin BLAminus in-in in-in 4E2 Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YLLA 1.4 Active DFGin BLAminus in-in in-in 4E3 Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YU2A 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 134 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 4YU2B 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YU2C 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 4YU2D 2.9 Active DFGin BLAminus in-in in-in 4H5 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6QU2A 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 6QU2B 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 6QU2C 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 6QU2D 2.9 Active DFGin BLAminus in-in in-in JHW Type1 134 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 6S11A 2.445 Active DFGin BLAminus in-in in-in KQE Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6S11B 2.445 Active DFGin BLAminus in-in in-in KQE Type1 136 - 480 None X321 3
Homo sapiens DYR1A_HUMAN 6S14A 1.05 Active DFGin BLAminus in-in in-in KQW Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6S17A 1.1 Active DFGin BLAminus in-in in-in KQK Type1 134 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 6S1BA 1.3 Active DFGin BLAminus in-in in-in KRQ Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6S1HA 1.05 Active DFGin BLAminus in-in in-in KQZ Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6S1IA 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6S1IB 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6S1IC 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 1
Homo sapiens DYR1A_HUMAN 6S1ID 2.38 Active DFGin BLAminus in-in in-in KR8 Type1 135 - 481 None X321 1
Homo sapiens DYR1A_HUMAN 6S1JA 1.408 Active DFGin BLAminus in-in in-in KRK Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6T6AA 2.8 Active DFGin BLAminus in-in in-in MLW Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6T6AB 2.8 Active DFGin BLAminus in-in in-in MLW Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6T6AC 2.8 Active DFGin BLAminus in-in in-in MLW Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6UWYA 2.95 Active DFGin BLAminus in-in in-in QKG Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6UWYB 2.95 Active DFGin BLAminus in-in in-in QKG Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6UWYC 2.95 Active DFGin BLAminus in-in in-in QKG Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 6UWYD 2.95 Active DFGin BLAminus in-in in-in QKG Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7FHSA 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7FHSB 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7FHSC 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7FHSD 2.42 Active DFGin BLAminus in-in in-in 4VZ Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7FHTA 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7FHTB 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7FHTC 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7FHTD 2.68 Active DFGin BLAminus in-in in-in 4WD Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 3ANQA 2.6 Active DFGin BLAminus in-in in-in EHB Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 3ANQB 2.6 Active DFGin BLAminus in-in in-in EHB Type1 133 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 3ANQC 2.6 Active DFGin BLAminus in-in in-in EHB Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 3ANQD 2.6 Active DFGin BLAminus in-in in-in EHB Type1 136 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 3ANRA 2.6 Active DFGin BLAminus in-in in-in HRM Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 3ANRB 2.6 Active DFGin BLAminus in-in in-in HRM Type1 133 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 3ANRC 2.6 Active DFGin BLAminus in-in in-in HRM Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 3ANRD 2.6 Active DFGin BLAminus in-in in-in HRM Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 4NCTA 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4NCTB 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4NCTC 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 479 None X301,X321 0
Homo sapiens DYR1A_HUMAN 4NCTD 2.597 Active DFGin BLAminus in-in in-in 2K2 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A3XA 2.26 Active DFGin BLAminus in-in in-in QIV Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 5A3XB 2.26 Active DFGin BLAminus in-in in-in QIV Type1 133 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 5A3XC 2.26 Active DFGin BLAminus in-in in-in QIV Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 5A3XD 2.26 Active DFGin BLAminus in-in in-in QIV Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4EA 2.68 Active DFGin BLAminus in-in in-in 7QQ Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4EB 2.68 Active DFGin BLAminus in-in in-in 7QQ Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4EC 2.68 Inactive DFGin BLAminus in-out in-in 7QQ Type1 134 - 473 None X321 0
Homo sapiens DYR1A_HUMAN 5A4ED 2.68 Active DFGin BLAminus in-in in-in 7QQ Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4LA 2.73 Active DFGin BLAminus in-in in-in ZC3 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4LB 2.73 Active DFGin BLAminus in-in in-in ZC3 Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4LC 2.73 Inactive DFGin BLAminus in-in out-in ZC3 Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A4LD 2.73 Active DFGin BLAminus in-in in-in ZC3 Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A4QA 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4QB 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4QC 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A4QD 2.37 Active DFGin BLAminus in-in in-in Y3L Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A4TA 2.15 Active DFGin BLAminus in-in in-in AJG Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4TB 2.15 Active DFGin BLAminus in-in in-in AJG Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A4TC 2.15 Active DFGin BLAminus in-in in-in AJG Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A4TD 2.15 Active DFGin BLAminus in-in in-in AJG Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A54A 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A54B 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 5A54C 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 5A54D 2.63 Active DFGin BLAminus in-in in-in 5PW Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIFA 2.22 Active DFGin BLAminus in-in in-in B5T Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIFB 2.22 Active DFGin BLAminus in-in in-in B5T Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIFC 2.22 Active DFGin BLAminus in-in in-in B5T Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIFD 2.22 Active DFGin BLAminus in-in in-in B5T Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIJA 2.42 Inactive DFGin BLAminus in-out in-in B5Z Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIJB 2.42 Active DFGin BLAminus in-in in-in B5Z Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIJD 2.42 Active DFGin BLAminus in-in in-in B5Z Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EILA 2.465 Active DFGin BLAminus in-in in-in B6B Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EILB 2.465 Active DFGin BLAminus in-in in-in B6B Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EILD 2.465 Active DFGin BLAminus in-in in-in B6B Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIPA 2.56 Inactive DFGin BLAminus in-out in-in B7B Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIPB 2.56 Active DFGin BLAminus in-in in-in B7B Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIPC 2.56 Active DFGin BLAminus in-in in-in B7B Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIPD 2.56 Active DFGin BLAminus in-in in-in B7B Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIQA 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIQB 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIQC 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIQD 2.3 Active DFGin BLAminus in-in in-in B6Z Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIRA 2.4 Active DFGin BLAminus in-in in-in B6H Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIRB 2.4 Active DFGin BLAminus in-in in-in B6H Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIRC 2.4 Active DFGin BLAminus in-in in-in B6H Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIRD 2.4 Active DFGin BLAminus in-in in-in B6H Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EISA 2.36 Active DFGin BLAminus in-in in-in B6N Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EISB 2.36 Active DFGin BLAminus in-in in-in B6N Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EISC 2.36 Active DFGin BLAminus in-in in-in B6N Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EISD 2.36 Active DFGin BLAminus in-in in-in B6N Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIVA 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIVB 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIVC 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EIVD 2.68 Active DFGin BLAminus in-in in-in B6Q Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EJ4A 2.88 Inactive DFGin BLAminus in-out in-in B7W Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EJ4B 2.88 Active DFGin BLAminus in-in in-in B7W Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EJ4C 2.88 Active DFGin BLAminus in-in in-in B7W Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6EJ4D 2.88 Active DFGin BLAminus in-in in-in B7W Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6YF8A 3.198 Active DFGin BLAminus in-in in-in OPW Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6YF8B 3.198 Active DFGin BLAminus in-in in-in OPW Type1 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6YF8C 3.198 Active DFGin BLAminus in-in in-in OPW Type1 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6YF8D 3.198 Active DFGin BLAminus in-in in-in OPW Type1 134 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NA 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NB 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NC 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5ND 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NE 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NF 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NG 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 137 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7Z5NH 2.77 Active DFGin BLAminus in-in in-in 3NG Type1 135 - 480 None X321 4
Homo sapiens DYR1A_HUMAN 8C3RA 2.06 Active DFGin BLAminus in-in in-in R7O Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3RB 2.06 Active DFGin BLAminus in-in in-in R7O Type1 136 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3GA 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3GB 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3GC 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3GD 2.08 Active DFGin BLAminus in-in in-in QS0 Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 2VX3A 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 2VX3B 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 2VX3C 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 2VX3D 2.4 Active DFGin BLAminus in-in in-in D15 Type1 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 2WO6A 2.5 Active DFGin BLAminus in-in in-in D15 Type1 133 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 2WO6B 2.5 Active DFGin BLAminus in-in in-in D15 Type1 136 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 4AZEA 3.15 Active DFGin BLAminus in-in in-in 3RA Type1 132 - 481 None X301,X321 0
Homo sapiens DYR1A_HUMAN 4AZEB 3.15 Active DFGin BLAminus in-in in-in 3RA Type1 135 - 481 None X301,X321 0
Homo sapiens DYR1A_HUMAN 4AZEC 3.15 Active DFGin BLAminus in-in in-in 3RA Type1 132 - 481 None X301,X321 0
Homo sapiens DYR1A_HUMAN 5AIKA 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 5AIKB 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 5AIKC 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 5AIKD 2.7 Active DFGin BLAminus in-in in-in AWR Type1 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7A4OA 1.9 Active DFGin BLAminus in-in in-in ANP Type1 136 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A4OB 1.9 Active DFGin BLAminus in-in in-in ANP Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A4WA 2.7 Active DFGin BLAminus in-in in-in QYH Type1 136 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A4WB 2.7 Active DFGin BLAminus in-in in-in QYH Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A55A 2.2 Active DFGin BLAminus in-in in-in QZ2 Type1 136 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A55B 2.2 Active DFGin BLAminus in-in in-in QZ2 Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A5BA 2.6 Active DFGin BLAminus in-in in-in MFR Type1 136 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7A5BB 2.6 Active DFGin BLAminus in-in in-in MFR Type1 134 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7O7KA 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7O7KB 1.82 Active DFGin BLAminus in-in in-in 6ZV LI Type1 Allosteric 133 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 7ZH8A 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 135 - 482 None X321 0
Homo sapiens DYR1A_HUMAN 7ZH8B 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 135 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7ZH8C 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 136 - 481 None X321 0
Homo sapiens DYR1A_HUMAN 7ZH8D 2.3 Active DFGin BLAminus in-in in-in IWU IWU Type1 Allosteric 135 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3QA 2.32 Active DFGin BLAminus in-in in-in RUT Type1.5_Back 134 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 8C3QB 2.32 Active DFGin BLAminus in-in in-in RUT Type1.5_Back 136 - 480 None X321 0
Homo sapiens DYR1A_HUMAN 6EIJC 2.42 Active DFGin BLAminus in-in in-in B5Z Type1.5_Front 135 - 479 None X321 0
Homo sapiens DYR1A_HUMAN 6UIPA 3.7 Inactive DFGin None in-in in-in Q8J Type1 131 - 479 None X321 0

DYRK1A (Dual specificity tyrosine-phosphorylation-regulated kinase 1A)

No non-human structures known.