Protein kinases in complex with BEZ

Total number of genes: 3
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 5WP1A
DFGin BLBtrans 1 8UOJA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CAMK MARK3 MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 8UOJA 1.6 Inactive DFGin BLBtrans out-out out-in X5I BEZ Type1 Allosteric
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Q38A 1.74 Active DFGin BLAminus in-in in-in BEZ Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Q4QA 1.45 Active DFGin BLAminus in-in in-in BEZ Type1
CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Q4QB 1.45 Active DFGin BLAminus in-in in-in BEZ Type1
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 5WP1A 1.4 Inactive DFGin BLAminus out-out in-in B7S BEZ Type1 Allosteric

Protein kinases in complex with BEZ

Total number of genes: 4
Total number of chains: 6
Spatial Dihedral Chains Representative
DFGin BLAminus 5 5WP1A
DFGin BLBtrans 1 8UOJA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6SNNA 1.817 Active DFGin BLAminus in-in in-in BEZ Type1
Homo sapiens CAMK MARK3 MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 8UOJA 1.6 Inactive DFGin BLBtrans out-out out-in X5I BEZ Type1 Allosteric
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Q38A 1.74 Active DFGin BLAminus in-in in-in BEZ Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Q4QA 1.45 Active DFGin BLAminus in-in in-in BEZ Type1
Homo sapiens CMGC CSNK2A1 CSK21_HUMAN Casein kinase II subunit alpha 6Q4QB 1.45 Active DFGin BLAminus in-in in-in BEZ Type1
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 5WP1A 1.4 Inactive DFGin BLAminus out-out in-in B7S BEZ Type1 Allosteric

Protein kinases in complex with BEZ

Total number of genes: 1
Total number of chains: 1
Spatial Dihedral Chains Representative
DFGin BLAminus 1 6SNNA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Cricetulus griseus AGC PRKACA KAPCA_CRIGR cAMP-dependent protein kinase catalytic subunit alpha 6SNNA 1.817 Active DFGin BLAminus in-in in-in BEZ Type1