Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLAminus | 19 | AF-P45983-K1A |
DFGin | ABAminus | 28 | 6ZR5B |
DFGin | None | 3 | 2G01B |
PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1UKHA | 2.35 | Inactive | DFGin | ABAminus | in-in | none-none | No_ligand | No_ligand | 9 - 363 | None | None | 17 |
4YR8A | 2.4 | Inactive | DFGin | ABAminus | in-in | none-out | No_ligand | No_ligand | 8 - 362 | None | None | 13 |
4YR8C | 2.4 | Inactive | DFGin | ABAminus | in-in | none-none | No_ligand | No_ligand | 10 - 362 | None | None | 16 |
4YR8E | 2.4 | Inactive | DFGin | ABAminus | out-out | out-out | No_ligand | No_ligand | 7 - 362 | None | None | 12 |
4YR8F | 2.4 | Inactive | DFGin | ABAminus | in-in | none-none | No_ligand | No_ligand | 10 - 362 | None | None | 16 |
6F5EB | 2.7 | Inactive | DFGin | ABAminus | in-in | out-out | No_ligand | No_ligand | 7 - 362 | None | None | 4 |
8X5MA | 2.0 | Inactive | DFGin | ABAminus | in-in | out-out | Y4O | Type1 | 7 - 363 | None | None | 12 |
6ZR5A | 2.699 | Inactive | DFGin | ABAminus | out-out | out-none | ANP | Type1 | 3 - 362 | None | None | 12 |
6ZR5B | 2.699 | Inactive | DFGin | ABAminus | out-out | out-out | ANP | Type1 | 4 - 362 | None | None | 0 |
1UKIA | 2.7 | Inactive | DFGin | ABAminus | in-in | out-none | 537 | Type1 | 9 - 363 | None | None | 13 |
4E73A | 2.27 | Inactive | DFGin | ABAminus | in-in | none-none | 0NR | Type1 | 8 - 361 | None | None | 15 |
4G1WA | 2.45 | Inactive | DFGin | ABAminus | in-in | none-none | G1W | Type1 | 8 - 361 | None | None | 15 |
4HYSA | 2.415 | Inactive | DFGin | ABAminus | in-in | none-none | 1BJ | Type1 | 8 - 361 | None | None | 15 |
4HYUA | 2.152 | Inactive | DFGin | ABAminus | in-in | none-none | 1BK | Type1 | 8 - 361 | None | None | 15 |
4IZYA | 2.3 | Inactive | DFGin | ABAminus | in-in | none-none | 1J2 | Type1 | 8 - 361 | None | None | 15 |
2XRWA | 1.33 | Inactive | DFGin | ABAminus | in-out | none-none | ANP | Type1 | 2 - 364 | None | None | 16 |
2XS0A | 2.6 | Inactive | DFGin | ABAminus | in-out | none-none | ANP | Type1 | 6 - 365 | T183V,Y185F | None | 14 |
3PZEA | 2.0 | Inactive | DFGin | ABAminus | in-in | none-out | CFK | Type1 | 7 - 362 | None | None | 9 |
4UX9A | 2.34 | Inactive | DFGin | ABAminus | in-out | in-in | ANP | Type1 | 8 - 363 | None | None | 5 |
4UX9C | 2.34 | Inactive | DFGin | ABAminus | in-out | in-in | ANP | Type1 | 8 - 363 | None | None | 7 |
4UX9D | 2.34 | Inactive | DFGin | ABAminus | in-in | in-out | ANP | Type1 | 9 - 364 | None | None | 0 |
4L7FA | 1.95 | Inactive | DFGin | ABAminus | in-in | none-out | 1V5 | Type1 | 7 - 362 | None | None | 13 |
3ELJA | 1.8 | Inactive | DFGin | ABAminus | in-in | none-out | GS7 | Type1 | 7 - 364 | None | None | 6 |
4AWIA | 1.91 | Inactive | DFGin | ABAminus | in-in | none-out | AQ2 | Type1 | 8 - 364 | None | None | 5 |
5LW1B | 3.2 | Inactive | DFGin | ABAminus | out-out | out-out | ADN | Type1 | 8 - 362 | None | None | 0 |
5LW1E | 3.2 | Inactive | DFGin | ABAminus | in-out | out-out | ADN | Type1 | 8 - 362 | None | None | 0 |
5LW1H | 3.2 | Inactive | DFGin | ABAminus | out-out | out-out | ADN | Type1 | 8 - 362 | None | None | 0 |
4QTDA | 1.5 | Inactive | DFGin | ABAminus | in-out | out-out | 38Z ANP | Type1 Allosteric | 6 - 363 | None | None | 3 |
3O2MA | 2.7 | Active | DFGin | BLAminus | in-in | in-in | 46A | Allosteric | 7 - 364 | T183E,Y185E | None | 0 |
3O2MB | 2.7 | Active | DFGin | BLAminus | in-in | in-in | 46A | Allosteric | 7 - 364 | T183E,Y185E | None | 0 |
3VULA | 2.81 | None | DFGin | BLAminus | in-in | in-none | No_ligand | No_ligand | 7 - 364 | C79V,C116S,C137V,C163A,C213V,C245S | None | 14 |
3VUIA | 2.8 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C79V,C116S,C163A,C245S | None | 3 |
3VUHA | 2.7 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C116S,C163A,C245S | None | 3 |
3VUDA | 3.5 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C245S | None | 3 |
3VUGA | 3.24 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C116S,C245S | None | 3 |
3VUKA | 2.95 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C79V,C116S,C137V,C163A,C245S | None | 3 |
3VUMA | 2.69 | None | DFGin | BLAminus | in-in | in-none | No_ligand | No_ligand | 7 - 364 | C41V,C79V,C116S,C137V,C163A,C213V,C245S | None | 14 |
AF-P45983-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 18 - 329 | None | None | 0 |
3O17A | 3.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 363 | T183E,Y185E | None | 0 |
3O17B | 3.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 363 | T183E,Y185E | None | 0 |
3V3VA | 2.7 | Active | DFGin | BLAminus | in-in | in-in | MYU | Type1 | 7 - 363 | None | None | 4 |
2G01A | 3.5 | Active | DFGin | BLAminus | out-in | in-in | 73Q | Type1 | 10 - 364 | T183E,Y185E | None | 0 |
2GMXA | 3.5 | Active | DFGin | BLAminus | in-in | in-in | 877 | Type1 | 8 - 364 | T183E,Y185E | None | 0 |
2H96A | 3.0 | Active | DFGin | BLAminus | in-in | in-in | 893 | Type1 | 7 - 364 | T183E,Y185E | None | 0 |
2H96B | 3.0 | Active | DFGin | BLAminus | in-in | in-in | 893 | Type1 | 7 - 364 | T183E,Y185E | None | 0 |
2NO3A | 3.2 | Active | DFGin | BLAminus | in-in | in-in | 859 | Type1 | 8 - 364 | T183E,Y185E | None | 0 |
2NO3B | 3.2 | Active | DFGin | BLAminus | in-in | in-in | 859 | Type1 | 7 - 363 | T183E,Y185E | None | 0 |
4UX9B | 2.34 | Inactive | DFGin | None | in-in | in-in | ANP | Type1 | 8 - 362 | None | None | 6 |
2G01B | 3.5 | Inactive | DFGin | None | in-in | in-in | 73Q | Type1 | 9 - 364 | T183E,Y185E | None | 0 |
2GMXB | 3.5 | Inactive | DFGin | None | in-out | in-in | 877 | Type1 | 7 - 364 | T183E,Y185E | None | 0 |
Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLAminus | 19 | AF-P45983-K1A |
DFGin | ABAminus | 28 | 6ZR5B |
DFGin | None | 3 | 2G01B |
Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homo sapiens | MK08_HUMAN | 1UKHA | 2.35 | Inactive | DFGin | ABAminus | in-in | none-none | No_ligand | No_ligand | 9 - 363 | None | None | 17 |
Homo sapiens | MK08_HUMAN | 4YR8A | 2.4 | Inactive | DFGin | ABAminus | in-in | none-out | No_ligand | No_ligand | 8 - 362 | None | None | 13 |
Homo sapiens | MK08_HUMAN | 4YR8C | 2.4 | Inactive | DFGin | ABAminus | in-in | none-none | No_ligand | No_ligand | 10 - 362 | None | None | 16 |
Homo sapiens | MK08_HUMAN | 4YR8E | 2.4 | Inactive | DFGin | ABAminus | out-out | out-out | No_ligand | No_ligand | 7 - 362 | None | None | 12 |
Homo sapiens | MK08_HUMAN | 4YR8F | 2.4 | Inactive | DFGin | ABAminus | in-in | none-none | No_ligand | No_ligand | 10 - 362 | None | None | 16 |
Homo sapiens | MK08_HUMAN | 6F5EB | 2.7 | Inactive | DFGin | ABAminus | in-in | out-out | No_ligand | No_ligand | 7 - 362 | None | None | 4 |
Homo sapiens | MK08_HUMAN | 8X5MA | 2.0 | Inactive | DFGin | ABAminus | in-in | out-out | Y4O | Type1 | 7 - 363 | None | None | 12 |
Homo sapiens | MK08_HUMAN | 6ZR5A | 2.699 | Inactive | DFGin | ABAminus | out-out | out-none | ANP | Type1 | 3 - 362 | None | None | 12 |
Homo sapiens | MK08_HUMAN | 6ZR5B | 2.699 | Inactive | DFGin | ABAminus | out-out | out-out | ANP | Type1 | 4 - 362 | None | None | 0 |
Homo sapiens | MK08_HUMAN | 1UKIA | 2.7 | Inactive | DFGin | ABAminus | in-in | out-none | 537 | Type1 | 9 - 363 | None | None | 13 |
Homo sapiens | MK08_HUMAN | 4E73A | 2.27 | Inactive | DFGin | ABAminus | in-in | none-none | 0NR | Type1 | 8 - 361 | None | None | 15 |
Homo sapiens | MK08_HUMAN | 4G1WA | 2.45 | Inactive | DFGin | ABAminus | in-in | none-none | G1W | Type1 | 8 - 361 | None | None | 15 |
Homo sapiens | MK08_HUMAN | 4HYSA | 2.415 | Inactive | DFGin | ABAminus | in-in | none-none | 1BJ | Type1 | 8 - 361 | None | None | 15 |
Homo sapiens | MK08_HUMAN | 4HYUA | 2.152 | Inactive | DFGin | ABAminus | in-in | none-none | 1BK | Type1 | 8 - 361 | None | None | 15 |
Homo sapiens | MK08_HUMAN | 4IZYA | 2.3 | Inactive | DFGin | ABAminus | in-in | none-none | 1J2 | Type1 | 8 - 361 | None | None | 15 |
Homo sapiens | MK08_HUMAN | 2XRWA | 1.33 | Inactive | DFGin | ABAminus | in-out | none-none | ANP | Type1 | 2 - 364 | None | None | 16 |
Homo sapiens | MK08_HUMAN | 2XS0A | 2.6 | Inactive | DFGin | ABAminus | in-out | none-none | ANP | Type1 | 6 - 365 | T183V,Y185F | None | 14 |
Homo sapiens | MK08_HUMAN | 3PZEA | 2.0 | Inactive | DFGin | ABAminus | in-in | none-out | CFK | Type1 | 7 - 362 | None | None | 9 |
Homo sapiens | MK08_HUMAN | 4UX9A | 2.34 | Inactive | DFGin | ABAminus | in-out | in-in | ANP | Type1 | 8 - 363 | None | None | 5 |
Homo sapiens | MK08_HUMAN | 4UX9C | 2.34 | Inactive | DFGin | ABAminus | in-out | in-in | ANP | Type1 | 8 - 363 | None | None | 7 |
Homo sapiens | MK08_HUMAN | 4UX9D | 2.34 | Inactive | DFGin | ABAminus | in-in | in-out | ANP | Type1 | 9 - 364 | None | None | 0 |
Homo sapiens | MK08_HUMAN | 4L7FA | 1.95 | Inactive | DFGin | ABAminus | in-in | none-out | 1V5 | Type1 | 7 - 362 | None | None | 13 |
Homo sapiens | MK08_HUMAN | 3ELJA | 1.8 | Inactive | DFGin | ABAminus | in-in | none-out | GS7 | Type1 | 7 - 364 | None | None | 6 |
Homo sapiens | MK08_HUMAN | 4AWIA | 1.91 | Inactive | DFGin | ABAminus | in-in | none-out | AQ2 | Type1 | 8 - 364 | None | None | 5 |
Homo sapiens | MK08_HUMAN | 5LW1B | 3.2 | Inactive | DFGin | ABAminus | out-out | out-out | ADN | Type1 | 8 - 362 | None | None | 0 |
Homo sapiens | MK08_HUMAN | 5LW1E | 3.2 | Inactive | DFGin | ABAminus | in-out | out-out | ADN | Type1 | 8 - 362 | None | None | 0 |
Homo sapiens | MK08_HUMAN | 5LW1H | 3.2 | Inactive | DFGin | ABAminus | out-out | out-out | ADN | Type1 | 8 - 362 | None | None | 0 |
Homo sapiens | MK08_HUMAN | 4QTDA | 1.5 | Inactive | DFGin | ABAminus | in-out | out-out | 38Z ANP | Type1 Allosteric | 6 - 363 | None | None | 3 |
Homo sapiens | MK08_HUMAN | 3O2MA | 2.7 | Active | DFGin | BLAminus | in-in | in-in | 46A | Allosteric | 7 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 3O2MB | 2.7 | Active | DFGin | BLAminus | in-in | in-in | 46A | Allosteric | 7 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 3VULA | 2.81 | None | DFGin | BLAminus | in-in | in-none | No_ligand | No_ligand | 7 - 364 | C79V,C116S,C137V,C163A,C213V,C245S | None | 14 |
Homo sapiens | MK08_HUMAN | 3VUIA | 2.8 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C79V,C116S,C163A,C245S | None | 3 |
Homo sapiens | MK08_HUMAN | 3VUHA | 2.7 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C116S,C163A,C245S | None | 3 |
Homo sapiens | MK08_HUMAN | 3VUDA | 3.5 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C245S | None | 3 |
Homo sapiens | MK08_HUMAN | 3VUGA | 3.24 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C116S,C245S | None | 3 |
Homo sapiens | MK08_HUMAN | 3VUKA | 2.95 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 364 | C79V,C116S,C137V,C163A,C245S | None | 3 |
Homo sapiens | MK08_HUMAN | 3VUMA | 2.69 | None | DFGin | BLAminus | in-in | in-none | No_ligand | No_ligand | 7 - 364 | C41V,C79V,C116S,C137V,C163A,C213V,C245S | None | 14 |
Homo sapiens | MK08_HUMAN | AF-P45983-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 18 - 329 | None | None | 0 |
Homo sapiens | MK08_HUMAN | 3O17A | 3.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 363 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 3O17B | 3.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 7 - 363 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 3V3VA | 2.7 | Active | DFGin | BLAminus | in-in | in-in | MYU | Type1 | 7 - 363 | None | None | 4 |
Homo sapiens | MK08_HUMAN | 2G01A | 3.5 | Active | DFGin | BLAminus | out-in | in-in | 73Q | Type1 | 10 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 2GMXA | 3.5 | Active | DFGin | BLAminus | in-in | in-in | 877 | Type1 | 8 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 2H96A | 3.0 | Active | DFGin | BLAminus | in-in | in-in | 893 | Type1 | 7 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 2H96B | 3.0 | Active | DFGin | BLAminus | in-in | in-in | 893 | Type1 | 7 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 2NO3A | 3.2 | Active | DFGin | BLAminus | in-in | in-in | 859 | Type1 | 8 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 2NO3B | 3.2 | Active | DFGin | BLAminus | in-in | in-in | 859 | Type1 | 7 - 363 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 4UX9B | 2.34 | Inactive | DFGin | None | in-in | in-in | ANP | Type1 | 8 - 362 | None | None | 6 |
Homo sapiens | MK08_HUMAN | 2G01B | 3.5 | Inactive | DFGin | None | in-in | in-in | 73Q | Type1 | 9 - 364 | T183E,Y185E | None | 0 |
Homo sapiens | MK08_HUMAN | 2GMXB | 3.5 | Inactive | DFGin | None | in-out | in-in | 877 | Type1 | 7 - 364 | T183E,Y185E | None | 0 |