8CGC

CSF1R (Macrophage colony-stimulating factor 1 receptor)
Group: TYR
Uniprot: CSF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 582 - 912
Resolu: 1.925

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-in LMR UIK Allosteric Type1 547 - 919 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        550        560        570 
mkkghhhhhh gqkpkyQVRW KIIESYEGNS YTFIDPTQLP 
       580        590        600        610 
YNEKWEFPRN NLQFGKTLGA GAFGKVVEAT AFGLGKEDAV 
       620        630        640        650 
LKVAVKMLKS TAHADEKEAL MSELKIMSHL GQHENIVNLL 
       660        670        680        690 
GACTHGGPVL VITEYCCYGD LLNFLRRKAE AMLGpslspg 
       746        756        766        776 
qdpegldked GRPLELRDLL HFSSQVAQGM AFLASKNCIH 
       786        796        806        816 
RDVAARNVLL TNGHVAKIGD FGLARDIMND SNYIVKGNAR 
       826        836        846        856 
LPVKWMAPES IFDCVYTVQS DVWSYGILLW EIFSLGLNPY 
       866        876        886        896 
PGILVNSKFY KLVKDGYQMA QPAFAPKNIY SIMQACWALE 
       906        916 
PTHRPTFQQI CSFLQEQAQE DRR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None