8SWE

FGFR2 (Fibroblast growth factor receptor 2)
Group: TYR
Uniprot: FGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 481 - 759
Resolu: 2.24

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in GSH WXQ Allosteric Type1 468 - 765 0
B Inactive DFGin BLAminus in-out in-in WXQ Type1 468 - 767 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       462        472        482        492 
shmgspmlag vseyeLPEDP KWEFPRDKLT LGKPLGEGCF 
       502        512        522        532 
GQVVMAEAVG IDKDKPKEAV TVAVKMLKDD ATEKDLSDLV 
       542        552        562        572 
SEMEMMKMIG KHKNIINLLG ACTQDGPLYV IVEYASKGNL 
       582        592        602        612 
REYLRARRPP gmeysydinr vpEEQMTFKD LVSCTYQLAR 
       622        632        642        652 
GMEYLASQKC IHRDLAARNV LVTENNVMKI ADFGLARDIN 
       662        672        682        692 
NIDYYKKTTN GRLPVKWMAP EALFDRVYTH QSDVWSFGVL 
       702        712        722        732 
MWEIFTLGGS PYPGIPVEEL FKLLKEGHRM DKPANCTNEL 
       742        752        762 
YMMMRDCWHA VPSQRPTFKQ LVEDLDRILT LTTNEe
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None