GAK (Cyclin-G-associated kinase)

Group: OTHER
Uniprot: GAK_HUMAN
Domain boundary: 40 - 315


Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 3 AF-O14976-K1A
DFGin ABAminus 7 4C57A
None None 2 4O38B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
5Y7ZA 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1 25 - 335 None None 0
5Y7ZB 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1 25 - 335 None None 0
4C57A 2.55 Inactive DFGin ABAminus in-out in-in FEF Type1 25 - 334 None None 0
4C57B 2.55 Inactive DFGin ABAminus out-out in-in FEF Type1 27 - 334 None None 0
4C59A 2.8 Inactive DFGin ABAminus in-in in-none FEF Type1 27 - 333 None None 27
5Y80A 2.5 Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric 25 - 332 None None 0
4C58A 2.16 Inactive DFGin ABAminus in-in in-none 824 Type1.5_Back 27 - 333 None None 27
AF-O14976-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 32 - 323 None None 0
4Y8DA 2.1 None DFGin BLAminus in-in in-none 49J Type1 27 - 333 None None 28
4Y8DB 2.1 None DFGin BLAminus in-in in-none 49J Type1 27 - 333 None None 28
4O38A 2.097 Inactive None None in-in in-none No_ligand No_ligand 25 - 334 None None 28
4O38B 2.097 Inactive None None in-in in-none No_ligand No_ligand 26 - 337 None None 24

GAK (Cyclin-G-associated kinase)

Group: OTHER
Total number of chains: 12
Spatial Dihedral Chains Representative
DFGin BLAminus 3 AF-O14976-K1A
DFGin ABAminus 7 4C57A
None None 2 4O38B
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens GAK_HUMAN 5Y7ZA 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1 25 - 335 None None 0
Homo sapiens GAK_HUMAN 5Y7ZB 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1 25 - 335 None None 0
Homo sapiens GAK_HUMAN 4C57A 2.55 Inactive DFGin ABAminus in-out in-in FEF Type1 25 - 334 None None 0
Homo sapiens GAK_HUMAN 4C57B 2.55 Inactive DFGin ABAminus out-out in-in FEF Type1 27 - 334 None None 0
Homo sapiens GAK_HUMAN 4C59A 2.8 Inactive DFGin ABAminus in-in in-none FEF Type1 27 - 333 None None 27
Homo sapiens GAK_HUMAN 5Y80A 2.5 Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric 25 - 332 None None 0
Homo sapiens GAK_HUMAN 4C58A 2.16 Inactive DFGin ABAminus in-in in-none 824 Type1.5_Back 27 - 333 None None 27
Homo sapiens GAK_HUMAN AF-O14976-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 32 - 323 None None 0
Homo sapiens GAK_HUMAN 4Y8DA 2.1 None DFGin BLAminus in-in in-none 49J Type1 27 - 333 None None 28
Homo sapiens GAK_HUMAN 4Y8DB 2.1 None DFGin BLAminus in-in in-none 49J Type1 27 - 333 None None 28
Homo sapiens GAK_HUMAN 4O38A 2.097 Inactive None None in-in in-none No_ligand No_ligand 25 - 334 None None 28
Homo sapiens GAK_HUMAN 4O38B 2.097 Inactive None None in-in in-none No_ligand No_ligand 26 - 337 None None 24

GAK (Cyclin-G-associated kinase)

No non-human structures known.