OTHER kinases in all conformations in complex with All ligands

Total number of genes: 49
Total number of chains: 453
Spatial Label Dihedral Label Chains Representative
DFGin BLAminus 252 AF-Q9NRP7-K1A
DFGin BLAplus 4 7JXUA
DFGin ABAminus 93 5I3OA
DFGin BLBminus 13 5O1VA
DFGin BLBplus 20 3P23C
DFGin BLBtrans 3 5J0AA
DFGin None 33 5O23A
DFGinter BABtrans 1 7QWKH
DFGinter None 1 7QWKF
DFGout BBAminus 5 6FDZU
DFGout None 13 7QWKA
None None 15 7BL1CCC
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Gene UniprotID Protein PDB Resol Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 AF-Q2M2I8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQA 1.95 Active DFGin BLAminus in-in in-in KSA Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQB 1.95 Active DFGin BLAminus in-in in-in KSA Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMCA 2.5 Active DFGin BLAminus in-in in-in YFV Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMCB 2.5 Active DFGin BLAminus in-in in-in YFV Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMDA 2.2 Active DFGin BLAminus in-in in-in ZRR Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMDB 2.2 Active DFGin BLAminus in-in in-in ZRR Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5L4QA 1.97 Active DFGin BLAminus in-in in-in LKB Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5L4QB 1.97 Active DFGin BLAminus in-in in-in LKB Type1
AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5TE0A 1.9 Active DFGin BLAminus in-in in-in XIN Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3OA 2.4 Inactive DFGin ABAminus in-in in-in IDV Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3OB 2.4 Inactive DFGin ABAminus in-in in-in IDV Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3RA 2.4 Inactive DFGin ABAminus in-in in-in IDK Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3RB 2.4 Inactive DFGin ABAminus in-in in-in IDK Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5IKWA 2.41 Inactive DFGin ABAminus in-in in-in 6BU Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase AF-Q9NSY1-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 4W9XA 2.14 Active DFGin BLAminus in-in in-in 3JW Type1
BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 4W9WA 1.72 Active DFGin BLAminus in-in in-in YDJ YDJ Type1 Allosteric
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 AF-O43683-K1A -1.0 Active DFGin BLAminus in-in in-out No_ligand No_ligand
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMA 2.202 Active DFGin BLAminus in-in in-out ADP Type1
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMB 2.202 Active DFGin BLAminus in-in in-out ADP Type1
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 6F7BA 2.0 Active DFGin BLAminus in-in in-out CVQ Type1
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4R8QA 2.31 Active DFGin BLAminus in-in in-out ADP Type1
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZA 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZB 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase AF-O00311-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F99A 2.33 None DFGin BLAminus in-in in-none ADP Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AA 2.17 None DFGin BLAminus in-in in-none ADP Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AC 2.17 None DFGin BLAminus in-in in-none ADP Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9BA 2.5 None DFGin BLAminus in-in in-none 0SY Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9BC 2.5 None DFGin BLAminus in-in in-none 0SY Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9CA 2.08 None DFGin BLAminus in-in in-none 0SX Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA7A 1.67 Active DFGin BLAminus in-in in-in ADP Type1
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA8A 1.79 Active DFGin BLAminus in-in in-in ADP BEF Type1 Allosteric
CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA6A 1.44 Active DFGin BLAminus in-in in-in 0SX BO3 Type1 Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha AF-O15111-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZA 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZB 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZC 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZD 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZE 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZF 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZG 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZH 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZI 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZJ 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZK 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZL 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQWA 5.6 Inactive None None in-in none-none No_ligand No_ligand
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQWB 5.6 Inactive None None in-in none-none No_ligand No_ligand
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQXA 5.4 Inactive None None in-out none-none No_ligand No_ligand
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQXB 5.4 Inactive None None in-out none-none No_ligand No_ligand
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQYA 5.2 Inactive None None in-out none-none No_ligand No_ligand
CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQYB 5.2 Inactive None None in-out none-none No_ligand No_ligand
DSTYK DUSTY_HUMAN Dual serine/threonine and tyrosine protein kinase AF-Q6XUX3-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
EIF2AK1 E2AK1_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 1 AF-Q9BQI3-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 2A1AB 2.8 Inactive DFGin ABAminus in-in in-out No_ligand No_ligand
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 8QELB 2.451 Inactive DFGin ABAminus in-in in-out UH3 Type1
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 2A19B 2.5 Inactive DFGin ABAminus in-in in-out ANP Type1
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 2A19C 2.5 Inactive DFGin ABAminus in-in none-none ANP Type1
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase AF-P19525-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KA 2.6 None DFGin BLAminus in-in in-none ADP Type1
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KB 2.6 None DFGin BLAminus in-in in-none ADP Type1
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KC 2.6 Inactive DFGin BLAminus in-in in-out ADP Type1
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3LA 3.1 Inactive DFGin None in-out in-none No_ligand No_ligand
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 3UIUA 2.903 Inactive DFGin None in-none in-none No_ligand No_ligand
EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 3UIUB 2.903 Inactive DFGin None in-none in-none No_ligand No_ligand
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 AF-Q9NZJ5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7OA 2.65 Inactive DFGin None out-out none-none 3Z6 Type1
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 7MF0AAA 2.809 Inactive DFGin None out-out none-none Z6P Type1
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 8EQ9AAA 2.86 Inactive DFGin None out-out none-none WPB Type1
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 8EQDAAA 2.92 Inactive DFGin None out-out out-none WPX Type1
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4G31A 2.28 Inactive DFGin None out-out none-out 0WH Type1.5_Back
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4G34A 2.7 Inactive DFGin None out-out none-out 924 Type1.5_Back
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4M7IA 2.34 Inactive DFGin None out-out none-out 27D Type1.5_Back
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 8EQEAAA 2.559 Inactive DFGin None out-out out-none WQ2 Type1.5_Back
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7JA 2.3 Inactive DFGout BBAminus out-out none-none 3Z1 Type1
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7KA 1.8 Inactive DFGout BBAminus out-out out-none 3Z3 Type2
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7LA 1.9 Inactive DFGout BBAminus out-out out-none 3Z4 Type2
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7NA 2.35 Inactive DFGout BBAminus out-out out-none 3Z5 Type2
EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7HA 2.0 Inactive DFGout None out-out none-none 3Z2 Type2
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 AF-Q9P2K8-K2A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3NA 3.01 None DFGin BLAminus out-out out-none KA4 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3OA 2.4 None DFGin BLAminus out-out out-none KA7 Type1.5_Back
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6A 2.8 Inactive DFGin None out-out none-out 38O Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6B 2.8 Inactive DFGin None out-out none-out 38O Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6C 2.8 Inactive DFGin None out-out out-out 38O Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6D 2.8 Inactive DFGin None out-out out-none 38O Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKH 2.3 Inactive DFGinter BABtrans out-out out-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKF 2.3 Inactive DFGinter None out-out out-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKA 2.3 Inactive DFGout None out-none none-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKB 2.3 Inactive DFGout None out-out out-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKC 2.3 Inactive DFGout None out-out out-none G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKD 2.3 Inactive DFGout None out-out out-out G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKE 2.3 Inactive DFGout None out-none none-none G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKG 2.3 Inactive DFGout None out-out out-none G41 Type1
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LA 2.61 Inactive DFGout None in-in none-none KAV Type2
EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LB 2.61 Inactive DFGout None in-in none-none KAV Type2
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7HB 2.9 Inactive DFGin ABAminus in-in in-in 4L5 Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 AF-O75460-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 5HGIA 2.584 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDFB 2.54 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3BA 2.57 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CA 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CB 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CC 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CD 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZCA 2.494 None DFGin BLAminus in-none in-in STU Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZCB 2.494 None DFGin BLAminus in-none in-in STU Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3KA 2.08 Active DFGin BLAminus in-in in-in SJS Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3EB 2.737 Inactive DFGin BLAminus out-out in-out SJV Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDFA 2.54 Inactive DFGin BLAminus out-out in-in N94 Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 7BMKA 1.85 Inactive DFGin BLAminus out-out in-in U4N Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 7BMKB 1.85 Inactive DFGin BLAminus out-out in-out U4N Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6URCA 2.2 Inactive DFGin BLAminus out-out in-in QFV Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6URCB 2.2 Inactive DFGin BLAminus out-out in-in QFV Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDDB 2.4 Inactive DFGin BLAminus in-out in-in N97 Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4U6RA 2.5 Inactive DFGin BLAminus out-out in-in 3E4 Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDBA 2.45 Inactive DFGin BLAminus out-out in-in N8S Type1.5_Back
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3EA 2.737 None DFGin BLAminus out-out none-none SJV Type1.5_Front
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDDA 2.4 Inactive DFGin BLAminus out-out in-out N97 Type1.5_Front
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDA 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDB 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDC 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W39A 1.736 Inactive DFGin BLBplus in-in none-none SJG Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W39B 1.736 Inactive DFGin BLBplus in-in none-none SJG Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23A 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23B 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23C 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23D 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3AA 2.606 Inactive DFGin BLBplus in-in none-out SJM Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3AB 2.606 Inactive DFGin BLBplus in-out none-out SJM Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7GA 2.6 Inactive DFGin None in-in none-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7GB 2.6 Inactive DFGin None in-in none-in No_ligand No_ligand
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7HA 2.9 Inactive DFGin None in-in in-in 4L5 Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9A 2.463 Inactive DFGout None out-out none-out 4K7 Type3
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9B 2.463 Inactive DFGout None out-out none-none 4K7 Type3
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9C 2.463 Inactive DFGout None out-out none-none 4K7 Type3
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6HX1A 2.14 Inactive None None none-none out-out GXK Type1
ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6HV0A 2.73 Inactive None None none-none out-out GUK Type1
ERN2 ERN2_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE2 AF-Q76MJ5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
GAK GAK_HUMAN Cyclin-G-associated kinase 5Y7ZA 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 5Y7ZB 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 4C57A 2.55 Inactive DFGin ABAminus in-out in-in FEF Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 4C57B 2.55 Inactive DFGin ABAminus out-out in-in FEF Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 4C59A 2.8 Inactive DFGin ABAminus in-in in-none FEF Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 5Y80A 2.5 Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric
GAK GAK_HUMAN Cyclin-G-associated kinase 4C58A 2.16 Inactive DFGin ABAminus in-in in-none 824 Type1.5_Back
GAK GAK_HUMAN Cyclin-G-associated kinase AF-O14976-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
GAK GAK_HUMAN Cyclin-G-associated kinase 4Y8DA 2.1 None DFGin BLAminus in-in in-none 49J Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 4Y8DB 2.1 None DFGin BLAminus in-in in-none 49J Type1
GAK GAK_HUMAN Cyclin-G-associated kinase 4O38A 2.097 Inactive None None in-in in-none No_ligand No_ligand
GAK GAK_HUMAN Cyclin-G-associated kinase 4O38B 2.097 Inactive None None in-in in-none No_ligand No_ligand
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin AF-Q8TF76-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 2WB8A 2.15 Active DFGin BLAminus in-in in-none No_ligand No_ligand
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 5HTBA 1.7 Active DFGin BLAminus in-in in-none No_ligand No_ligand
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 5HTCA 1.5 Active DFGin BLAminus in-in in-none No_ligand No_ligand
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G39A 1.45 Active DFGin BLAminus in-in in-none 5ID Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 2VUWA 1.8 Active DFGin BLAminus in-in in-none 5ID Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3DLZA 1.85 Active DFGin BLAminus in-in in-none AMP Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3E7VA 2.0 Active DFGin BLAminus in-in in-none DZO Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3F2NA 1.8 Active DFGin BLAminus in-in in-none IZZ Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3FMDA 2.0 Active DFGin BLAminus in-in in-none IQB Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3IQ7A 2.0 Active DFGin BLAminus in-in in-none 5ID Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 4OUCA 1.9 Active DFGin BLAminus in-in in-none 5ID Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 4QTCA 1.4 Active DFGin BLAminus in-in in-none 38Z Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G34A 1.76 Active DFGin BLAminus in-in in-none 5ID Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G35A 1.55 Active DFGin BLAminus in-in in-none EKK Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G36A 1.46 Active DFGin BLAminus in-in in-none EKH Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G37A 1.48 Active DFGin BLAminus in-in in-none FTU Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G38A 1.47 Active DFGin BLAminus in-in in-none TBN Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z57A 1.5 Active DFGin BLAminus in-in in-none Q8W Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z58A 1.8 Active DFGin BLAminus in-in in-none Q9B Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z59A 2.0 Active DFGin BLAminus in-in in-none Q98 Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5CA 1.75 Inactive DFGin BLAminus out-out in-none PQ5 Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5DA 1.75 Active DFGin BLAminus in-in in-none Q8Q Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5EA 1.5 Active DFGin BLAminus in-in in-none Q8K Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 7AVQA 1.65 Active DFGin BLAminus in-in in-none S1Z Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 7OPSA 2.38 Active DFGin BLAminus in-in in-none 07C Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 8RDKA 2.0 Active DFGin BLAminus in-in in-none YQT Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 7SQMA 1.78 Active DFGin BLAminus in-in in-none A5G Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G3AA 1.43 Inactive DFGin BLAminus in-out in-none 5ID Type1
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z56A 1.9 Inactive DFGin BLAminus out-out in-none Q7Q Type1.5_Back
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5BA 1.9 Inactive DFGin BLAminus out-out in-none Q7Z Type1.5_Back
HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5AA 1.55 Inactive DFGin BLAminus out-out in-none Q8B Type1.5_Front
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta AF-O14920-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CB 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CC 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CD 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CF 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CA 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand
IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CE 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand
IKBKE IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon AF-Q14164-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6O5ZA 2.285 Inactive DFGin BLAminus in-in out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JXUA 2.44 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JXUB 2.44 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7MONA 2.23 Inactive DFGin BLAplus out-out out-out ZL1 Type1
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4MWIA 1.7 Inactive DFGin BLBminus in-in out-out PXN Allosteric
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6BWKA 2.79 Inactive DFGin BLBminus in-none none-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JW7A 2.63 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 8SLZA 2.3 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4M67A 1.9 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK6A 2.41 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK5A 2.5 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KO1A 2.16 Inactive DFGin BLBminus in-in out-out 6UY Type1
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6O5ZB 2.285 Inactive DFGout None in-out none-out LN4 Type2
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KNJA 2.88 Inactive None None in-in none-out 6UX Type1
MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KNJB 2.88 Inactive None None in-in none-out 6UX Type1
MOS MOS_HUMAN Proto-oncogene serine/threonine-protein kinase mos AF-P00540-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
PBK TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase AF-Q96KB5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
PBK TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase 5J0AA 2.74 Inactive DFGin BLBtrans out-out in-in No_ligand No_ligand
PBK TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase 5J0AB 2.74 Inactive DFGin BLBtrans out-out in-in No_ligand No_ligand
PDIK1L PDK1L_HUMAN Serine/threonine-protein kinase PDIK1L AF-Q8N165-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
PEAK1 PEAK1_HUMAN Inactive tyrosine-protein kinase PEAK1 6BHCA 2.3 None DFGin BLAminus out-none in-out No_ligand No_ligand
PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SORA 3.96 Inactive DFGin BLBminus out-out out-out ADP Type1
PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SRQW 6.2 Inactive None None out-none out-out No_ligand No_ligand
PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 7BL1CCC 9.8 Inactive None None out-none out-out No_ligand No_ligand
PINK1 PINK1_HUMAN Serine/threonine-protein kinase PINK1, mitochondrial AF-Q9BXM7-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
PKDCC PKDCC_HUMAN Extracellular tyrosine-protein kinase PKDCC AF-Q504Y2-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase AF-Q99640-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 3P1AA 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCVA 1.92 Active DFGin BLAminus in-in in-in 1N1 Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCWA 2.25 Active DFGin BLAminus in-in in-in 93J Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCWB 2.25 Inactive DFGin BLAminus in-out in-in 93J Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCXA 2.7 Active DFGin BLAminus in-in in-in H8H Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCYA 1.56 Active DFGin BLAminus in-in in-in DB8 Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCZA 1.5 Active DFGin BLAminus in-in in-in XZN Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD0A 2.13 Active DFGin BLAminus in-in in-in 8X7 Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD1A 1.7 Active DFGin BLAminus in-in in-in P48 Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD3A 1.8 Active DFGin BLAminus in-in in-in H8H Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6CA 2.2 Active DFGin BLAminus in-in in-in QGR Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6CB 2.2 Active DFGin BLAminus in-in in-in QGR Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6DB 2.35 Active DFGin BLAminus in-in in-in QGY Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6EB 2.15 Active DFGin BLAminus in-in in-in QGI Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8WJYA 1.88 Active DFGin BLAminus in-in in-in W9X Type1
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6DA 2.35 Active DFGin BLAminus in-in in-in QGY Type1.5_Back
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6EA 2.15 Active DFGin BLAminus in-in in-in QGI Type1.5_Back
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6FA 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back
PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6FB 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back
PRAG1 PRAG1_HUMAN Inactive tyrosine-protein kinase PRAG1 5VE6A 2.953 Inactive None None none-none none-none No_ligand No_ligand
RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAUC 2.6 Active DFGin BLAminus in-in in-none ADP Type1
RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAVB 2.1 Active DFGin BLAminus in-in in-none ACP Type1
RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAVD 2.1 Active DFGin BLAminus in-in in-none ACP Type1
SBK1 SBK1_HUMAN Serine/threonine-protein kinase SBK1 AF-Q52WX2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
SBK2 SBK2_HUMAN Serine/threonine-protein kinase SBK2 AF-P0C263-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
SBK3 SBK3_HUMAN Uncharacterized serine/threonine-protein kinase SBK3 AF-P0C264-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
STK16 STK16_HUMAN Serine/threonine-protein kinase 16 AF-O75716-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
STK16 STK16_HUMAN Serine/threonine-protein kinase 16 2BUJA 2.6 Active DFGin BLAminus in-in in-in STU STU Type1 Allosteric
STK16 STK16_HUMAN Serine/threonine-protein kinase 16 2BUJB 2.6 Active DFGin BLAminus in-in in-in STU STU Type1 Type1
STK35 STK35_HUMAN Serine/threonine-protein kinase 35 AF-Q8TDR2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
STK36 STK36_HUMAN Serine/threonine-protein kinase 36 AF-Q9NRP7-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 AF-Q9UHD2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUUA 1.8 Active DFGin BLAminus in-in in-in BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUUB 1.8 Active DFGin BLAminus in-in in-in BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUTA 2.6 Inactive DFGin BLAminus in-in in-out BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUTB 2.6 Inactive DFGin BLAminus in-in in-out BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IW0A 4.0 Active DFGin BLAminus in-in in-in BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6O8BA 3.4 Inactive DFGin BLAminus out-out in-in BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6O8BB 3.4 Inactive DFGin BLAminus in-in out-in BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6NT9A 3.3 Inactive DFGin BLBplus out-out none-out No_ligand No_ligand
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6NT9B 3.3 Inactive DFGin BLBplus out-out none-out No_ligand No_ligand
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 5W5VA 3.645 Inactive DFGin BLBplus out-out none-none ANW Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6BODA 3.197 Inactive DFGin BLBplus out-out out-none E0P Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6RSTA 3.29 Inactive DFGin BLBplus out-out out-in KHQ Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IWOA 2.61 Inactive DFGin BLBplus out-out out-in 1H4 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IM0A 2.4 Inactive DFGin BLBplus out-out none-none 1FV Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IM2A 2.5 Inactive DFGin BLBplus out-out none-none BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IM3A 3.342 Inactive DFGin BLBplus out-out none-none BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6BNYA 3.341 Inactive DFGin None out-out none-none E0M Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6BOEA 3.598 Inactive DFGin None out-out none-in E0S Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6CQ0A 3.19 Inactive DFGin None out-out none-out F8M Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6CQ4A 3.2 Inactive DFGin None out-out none-in F8P Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6CQ5A 3.354 Inactive DFGin None out-out none-none F8S Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6RSRA 3.15 Inactive DFGin None out-out out-in KHT Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6RSUA 2.75 Inactive DFGin None out-out out-in KJB Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IWPA 3.065 Inactive DFGin None out-out out-in BX7 Type1
TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IWQA 3.0 Inactive DFGin None out-out out-in 1FV Type1
TLK1 TLK1_HUMAN Serine/threonine-protein kinase tousled-like 1 AF-Q9UKI8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
TLK2 TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 AF-Q86UE8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
TLK2 TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 5O0YA 2.86 Inactive DFGin BLAminus out-out in-in AGS Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK AF-Q96S44-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZAA 1.9 Active DFGin BLAminus in-in in-none DUI Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZAC 1.9 Active DFGin BLAminus in-in in-none DUI Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZBA 2.02 Active DFGin BLAminus in-in in-none DQ4 Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZBC 2.02 Active DFGin BLAminus in-in in-none DQ4 Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZCA 1.71 Active DFGin BLAminus in-in in-none DO0 Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZCC 1.71 Active DFGin BLAminus in-in in-none DO0 Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZDA 2.05 Active DFGin BLAminus in-in in-none DVO Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZDC 2.05 Active DFGin BLAminus in-in in-none DVO Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 6WQXC 2.53 Active DFGin BLAminus in-in in-none ANP Type1
TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 6WQXD 2.53 Active DFGin BLAminus in-in in-none ANP Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3CEKA 2.3 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
TTK TTK_HUMAN Dual specificity protein kinase TTK 3DBQA 2.7 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
TTK TTK_HUMAN Dual specificity protein kinase TTK 2ZMCA 3.14 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
TTK TTK_HUMAN Dual specificity protein kinase TTK 6GVJA 2.41 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
TTK TTK_HUMAN Dual specificity protein kinase TTK 5NTTA 2.75 Inactive DFGin ABAminus out-out out-out SVE Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5LJJA 3.0 Inactive DFGin ABAminus out-out out-out AD5 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5MRBA 2.2 Inactive DFGin ABAminus out-out out-out C5N Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EH0A 2.18 Inactive DFGin ABAminus out-out out-out 5NW Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 6H3KA 2.48 Inactive DFGin ABAminus out-out out-none FMW Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4JS8A 1.94 Inactive DFGin ABAminus in-out out-out 1PF Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4JT3A 2.2 Inactive DFGin ABAminus out-out out-out 1PH Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4O6LA 2.38 Inactive DFGin ABAminus out-out out-none 2QK Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4O6LB 2.38 Inactive DFGin ABAminus out-out out-out 2QK Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4ZEGA 2.33 Inactive DFGin ABAminus in-in out-none 052 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7CILA 2.3 Inactive DFGin ABAminus in-in out-out FZR Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7CHNA 2.4 Inactive DFGin ABAminus in-out out-out FZL Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7CHTA 2.4 Inactive DFGin ABAminus in-in out-none FZO Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7CJAA 2.49 Inactive DFGin ABAminus in-in out-out G0U Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7CLHA 2.9 Inactive DFGin ABAminus out-out out-out G5C Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4D2SA 2.5 Inactive DFGin ABAminus out-out none-none DYK Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 6TN9A 2.6 Inactive DFGin ABAminus in-out out-out NN5 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 6TNCA 2.3 Inactive DFGin ABAminus in-in out-out O23 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 6N6OA 2.6 Inactive DFGin ABAminus out-out out-none KE7 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3GFWA 2.74 Inactive DFGin ABAminus out-out none-out S22 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4BHZA 2.85 Inactive DFGin ABAminus out-out out-out Z0B Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4BI0A 2.84 Inactive DFGin ABAminus out-out out-out Z0W Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4BI1A 2.7 Inactive DFGin ABAminus out-out out-out ZO6 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4BI2A 3.11 Inactive DFGin ABAminus out-out out-out ZO8 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4EA 2.6 Inactive DFGin ABAminus out-out out-out 4T9 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4FA 2.36 Inactive DFGin ABAminus out-out out-out 7CE Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4GA 2.65 Inactive DFGin ABAminus out-out none-out 7RO Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4HA 2.8 Inactive DFGin ABAminus out-out none-none 7RO Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4IA 2.65 Inactive DFGin ABAminus out-out out-none X20 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4JA 2.5 Inactive DFGin ABAminus in-in out-out X21 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4CV8A 3.0 Inactive DFGin ABAminus out-none out-out 3D7 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4CV9A 2.5 Inactive DFGin ABAminus out-out out-out W2K Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 4CVAA 2.5 Inactive DFGin ABAminus out-out out-out WBI Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP0A 2.15 Inactive DFGin ABAminus out-out out-out AU5 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP1A 2.05 Inactive DFGin ABAminus in-out out-out O38 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP2A 2.8 Inactive DFGin ABAminus in-in out-out PWU Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EHLA 2.66 Inactive DFGin ABAminus out-none out-out 0SQ Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EHOA 2.18 Inactive DFGin ABAminus out-out out-out 5O1 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EHYA 2.26 Inactive DFGin ABAminus out-out out-out 5O4 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EI2A 2.67 Inactive DFGin ABAminus out-out out-out 5O7 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EI6A 2.01 Inactive DFGin ABAminus in-out out-out 5OQ Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5EI8A 2.17 Inactive DFGin ABAminus out-out out-out 5OE Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5N87A 2.29 Inactive DFGin ABAminus out-out out-out N66 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP6A 2.1 Inactive DFGin ABAminus in-in out-out PWU Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP7A 2.45 Inactive DFGin ABAminus out-out out-out SVE Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5O91A 3.2 Inactive DFGin ABAminus out-out out-out C5N Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 6B4WA 2.9 Inactive DFGin ABAminus in-none out-out CQ7 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 2X9EA 3.1 Inactive DFGin ABAminus out-out out-out SVE Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3VQUA 2.4 Inactive DFGin ABAminus out-out out-out O22 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3WYXA 2.9 Inactive DFGin ABAminus in-out out-out O38 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3WYYA 3.05 Inactive DFGin ABAminus in-out out-out O17 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5N7VA 2.52 Inactive DFGin ABAminus out-out out-out 8PT Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5N84A 2.3 Inactive DFGin ABAminus out-out out-out 8Q5 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5N93A 2.1 Inactive DFGin ABAminus out-out out-out 8QE Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5NA0A 2.9 Inactive DFGin ABAminus out-out out-out 8QZ Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMNA 2.7 Inactive DFGin ABAminus out-out out-out ATP Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMOA 2.4 Inactive DFGin ABAminus out-out out-out STU Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMPA 2.3 Inactive DFGin ABAminus out-out out-out CX4 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP3A 2.7 Inactive DFGin ABAminus out-out out-out AU5 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP4A 2.85 Inactive DFGin ABAminus out-out out-out O38 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 2ZMDA 2.88 Inactive DFGin ABAminus out-out out-out 537 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7LQDA 1.95 Inactive DFGin ABAminus out-out out-out YB4 TOE Type1 Allosteric
TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP5A 2.8 Inactive DFGin ABAminus out-out none-out 7RO 1KA Type1 Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 6TNDA 2.58 Inactive DFGin ABAminus in-in out-none 8RH Type1.5_Back
TTK TTK_HUMAN Dual specificity protein kinase TTK 3W1FA 2.7 Inactive DFGin ABAminus in-in out-out 1O5 Type1.5_Back
TTK TTK_HUMAN Dual specificity protein kinase TTK 3WZJA 2.75 Inactive DFGin ABAminus in-in out-out O43 Type1.5_Back
TTK TTK_HUMAN Dual specificity protein kinase TTK 3WZKA 2.3 Inactive DFGin ABAminus in-in out-out O23 Type1.5_Back
TTK TTK_HUMAN Dual specificity protein kinase TTK 5NADA 2.8 Inactive DFGin ABAminus in-in out-none 8RH Type1.5_Back
TTK TTK_HUMAN Dual specificity protein kinase TTK 6TNBA 2.65 Inactive DFGin ABAminus out-out out-out 8QW Type1.5_Front
TTK TTK_HUMAN Dual specificity protein kinase TTK 5N9SA 2.3 Inactive DFGin ABAminus out-out out-out 8QW Type1.5_Front
TTK TTK_HUMAN Dual specificity protein kinase TTK AF-P33981-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
TTK TTK_HUMAN Dual specificity protein kinase TTK 3H9FA 2.6 Inactive DFGin BLAplus in-none out-out 92M Type1
TTK TTK_HUMAN Dual specificity protein kinase TTK 7CHMA 2.65 Inactive DFGin None in-in out-out FZF Type1
UHMK1 UHMK1_HUMAN Serine/threonine-protein kinase Kist AF-Q8TAS1-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 AF-O75385-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6MNHA 1.73 Inactive DFGin BLAminus in-in in-out JVD Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 8SV9A 2.3 Active DFGin BLAminus in-in in-in WXH Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 8SV9B 2.3 Active DFGin BLAminus in-in in-in WXH Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNOA 1.56 Active DFGin BLAminus in-in in-in 3RF Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPA 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPB 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPC 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPD 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 5CI7A 1.74 Active DFGin BLAminus in-in in-in 51W Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6QASA 1.75 Active DFGin BLAminus in-in in-in 34W Type1
ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6QASB 1.75 Active DFGin BLAminus in-in in-in 34W 34W Type1 Allosteric
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 AF-Q8IYT8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATA 2.77 None DFGin BLAminus out-out in-none FE7 Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATB 2.77 None DFGin BLAminus out-out in-none FE7 Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATC 2.77 None DFGin BLAminus out-out in-none FE7 Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATD 2.77 None DFGin BLAminus in-out in-none FE7 Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAUA 2.48 Inactive DFGin BLAminus in-in in-out 1FV Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAUB 2.48 None DFGin BLAminus in-in in-none 1FV Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAUC 2.48 None DFGin BLAminus in-in in-none 1FV Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVA 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVB 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVC 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVD 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDA 2.7 None DFGin BLAminus out-out in-none EDJ Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDB 2.7 None DFGin BLAminus in-out in-none EDJ Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDC 2.7 None DFGin BLAminus out-out in-none EDJ Type1
ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDD 2.7 None DFGin BLAminus out-out in-none EDJ Type1
ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 AF-Q6PHR2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDYU 1.7 Inactive DFGin BLAminus out-out in-in DB8 DB8 Type1 Allosteric
ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDZU 2.55 Inactive DFGout BBAminus out-out out-out C87 Type1
ULK4 ULK4_HUMAN Serine/threonine-protein kinase ULK4 6U5LA 1.75 Inactive DFGin ABAminus out-none in-in 3RJ Type1
ULK4 ULK4_HUMAN Serine/threonine-protein kinase ULK4 6TSZU 1.9 Inactive DFGin ABAminus out-none in-in AGS Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase AF-P30291-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
WEE1 WEE1_HUMAN Wee1-like protein kinase 2Z2WA 2.22 Active DFGin BLAminus in-in in-in 770 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 7N3UA 2.65 Inactive DFGin BLAminus out-out in-in 05J Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 8BJUA 1.53 Inactive DFGin BLAminus in-out in-in QT9 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 2IN6A 1.9 Active DFGin BLAminus in-in in-in 839 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 2IO6A 2.2 Active DFGin BLAminus in-in in-in 330 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 3BI6A 2.2 Inactive DFGin BLAminus in-out in-in 396 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 3BIZA 2.2 Active DFGin BLAminus in-in in-in 61E Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 3CQEA 2.5 Inactive DFGin BLAminus in-out in-in P91 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 3CR0A 2.3 Inactive DFGin BLAminus in-out in-in 809 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5V5YA 1.9 Active DFGin BLAminus in-in in-in 8X7 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC3A 1.97 Inactive DFGin BLAminus out-out in-in DB8 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC4A 2.1 Inactive DFGin BLAminus in-out in-in XZN Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC5A 1.93 Inactive DFGin BLAminus in-out in-in 96M Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC6A 2.0 Active DFGin BLAminus in-in in-in P48 Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD2A 2.05 Inactive DFGin BLAminus out-out in-in 34W Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD4A 2.02 Active DFGin BLAminus in-in in-in 99J Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD5A 2.05 Active DFGin BLAminus in-in in-in 99M Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD7A 2.08 Active DFGin BLAminus in-in in-in 99V Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD8A 1.85 Active DFGin BLAminus in-in in-in 98M Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD9A 1.87 Inactive DFGin BLAminus in-out in-in 98G Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 5VDAA 2.1 Inactive DFGin BLAminus in-out in-in 98D Type1
WEE1 WEE1_HUMAN Wee1-like protein kinase 1X8BA 1.81 Active DFGin BLAminus in-in in-in 824 Type1
WEE2 WEE2_HUMAN Wee1-like protein kinase 2 AF-P0C1S8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
WEE2 WEE2_HUMAN Wee1-like protein kinase 2 5VDKA 2.7 Active DFGin BLAminus in-in in-in 8X7 Type1
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 AF-Q9H4A3-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYA 2.458 None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYB 2.458 None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8A 2.006 Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8B 2.006 Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9A 2.5 Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9B 2.5 Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 4PWNA 1.84 Inactive DFGin None out-none out-none No_ligand No_ligand
WNK2 WNK2_HUMAN Serine/threonine-protein kinase WNK2 AF-Q9Y3S1-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 AF-Q9BYP7-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O21A 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O21B 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 8EDHC 3.111 None DFGin BLAminus out-none out-none No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O26A 2.379 Active DFGin BLAminus out-none in-in ANP Type1
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O26B 2.379 Active DFGin BLAminus out-none in-in ANP Type1
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 8EDHA 3.111 None DFGin BLAminus out-none out-none WGK Type1
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VA 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VB 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2CA 2.4 Inactive DFGin BLBminus out-none out-in No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2BB 2.038 Inactive DFGin BLBminus out-none out-none KS1 Type1
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2BA 2.038 Inactive DFGin BLBtrans out-none out-out KS1 Type1
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O23A 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand
WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O23B 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand
WNK4 WNK4_HUMAN Serine/threonine-protein kinase WNK4 AF-Q96J92-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand

OTHER kinases in all conformations in complex with All ligands

Total number of genes: 74
Total number of chains: 753
Spatial Label Dihedral Label Chains Representative
DFGin BLAminus 387 AF-Q9NRP7-K1A
DFGin BLAplus 10 7JXUA
DFGin ABAminus 121 7Q52AAA
DFGin BLBminus 56 5O1VA
DFGin BLBplus 33 5UV4A
DFGin BLBtrans 6 5DRBA
DFGin None 69 5GZAA
DFGinter BABtrans 1 7QWKH
DFGinter None 3 7QWKF
DFGout BBAminus 8 6FDZU
DFGout None 28 4I93A
None None 31 7BL1CCC
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Resol Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68A 2.0 Inactive DFGin BLBminus out-out out-in PDO Allosteric
Arabidopsis thaliana BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68B 2.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I92A 1.6 Inactive DFGout None out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93A 1.5 Inactive DFGout None out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93B 1.5 Inactive DFGout None out-out out-none No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94A 1.8 Inactive DFGout None out-out out-out ANP Type1
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94B 1.8 Inactive DFGout None out-out out-out ANP Type1
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAA 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAB 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAC 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAD 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4A 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4B 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4C 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4D 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana T1N2412 Q94K14_ARATH non-specific serine/threonine protein kinase 8K20B 3.7 Inactive DFGin BLAminus in-out in-none No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TB 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TE 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TH 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TK 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TN 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5UB 3.9 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5VB 4.25 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J6IB 3.7 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5WB 3.7 Inactive DFGin BLAplus in-in out-none No_ligand No_ligand
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIA 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIB 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIC 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYID 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIE 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIF 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIG 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIH 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJA 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJB 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJC 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJD 2.59 Inactive DFGin None out-none out-none ATP Type1
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXJA 1.92 Inactive DFGinter None out-out in-in MAP Type1
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXKA 1.99 Inactive DFGinter None out-out in-in MAP Type1
Cydia pomonella granulosis virus PK1 A0A097P1P8_GVCP PK-1 6VVGA 2.01 Inactive DFGin BLAminus out-out in-in AMP Type1
Cydia pomonella granulosis virus PK1 A0A097P1P8_GVCP PK-1 6VVGB 2.01 Inactive DFGin BLAminus out-out in-in AMP Type1
Danio rerio POMK SG196_DANRE Protein O-mannose kinase 5GZAA 2.0 Inactive DFGin None none-none in-out ADP ZZ1 Type1 Allosteric
Drosophila melanogaster BUBR1 A1Z6I7_DROME Bub1-related kinase 6JKKA 1.85 Active DFGin BLAminus in-in in-out No_ligand No_ligand
Drosophila melanogaster BUBR1 A1Z6I7_DROME Bub1-related kinase 6JKMA 1.95 Active DFGin BLAminus in-in in-out ADP Type1
Drosophila melanogaster PAN3 PAN3_DROME PAN2-PAN3 deadenylation complex subunit PAN3 4BWPA 3.6 Inactive DFGin None out-none out-none AN2 Type1
Drosophila melanogaster PAN3 PAN3_DROME PAN2-PAN3 deadenylation complex subunit PAN3 4BWPB 3.6 Inactive DFGin None out-none out-none AN2 Type1
Equus caballus MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0A 2.746 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Equus caballus MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0B 2.746 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Equus caballus MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0C 2.746 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 AF-Q2M2I8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQA 1.95 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 4WSQB 1.95 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMCA 2.5 Active DFGin BLAminus in-in in-in YFV Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMCB 2.5 Active DFGin BLAminus in-in in-in YFV Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMDA 2.2 Active DFGin BLAminus in-in in-in ZRR Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 8GMDB 2.2 Active DFGin BLAminus in-in in-in ZRR Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5L4QA 1.97 Active DFGin BLAminus in-in in-in LKB Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5L4QB 1.97 Active DFGin BLAminus in-in in-in LKB Type1
Homo sapiens AAK1 AAK1_HUMAN AP2-associated protein kinase 1 5TE0A 1.9 Active DFGin BLAminus in-in in-in XIN Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3OA 2.4 Inactive DFGin ABAminus in-in in-in IDV Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3OB 2.4 Inactive DFGin ABAminus in-in in-in IDV Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3RA 2.4 Inactive DFGin ABAminus in-in in-in IDK Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5I3RB 2.4 Inactive DFGin ABAminus in-in in-in IDK Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 5IKWA 2.41 Inactive DFGin ABAminus in-in in-in 6BU Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase AF-Q9NSY1-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 4W9XA 2.14 Active DFGin BLAminus in-in in-in 3JW Type1
Homo sapiens BMP2K BMP2K_HUMAN BMP-2-inducible protein kinase 4W9WA 1.72 Active DFGin BLAminus in-in in-in YDJ YDJ Type1 Allosteric
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 AF-O43683-K1A -1.0 Active DFGin BLAminus in-in in-out No_ligand No_ligand
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMA 2.202 Active DFGin BLAminus in-in in-out ADP Type1
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4QPMB 2.202 Active DFGin BLAminus in-in in-out ADP Type1
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 6F7BA 2.0 Active DFGin BLAminus in-in in-out CVQ Type1
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 4R8QA 2.31 Active DFGin BLAminus in-in in-out ADP Type1
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZA 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
Homo sapiens BUB1 BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 5DMZB 2.4 Inactive DFGin BLAminus in-out in-in ADP Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase AF-O00311-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F99A 2.33 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AA 2.17 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9AC 2.17 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9BA 2.5 None DFGin BLAminus in-in in-none 0SY Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9BC 2.5 None DFGin BLAminus in-in in-none 0SY Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 4F9CA 2.08 None DFGin BLAminus in-in in-none 0SX Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA7A 1.67 Active DFGin BLAminus in-in in-in ADP Type1
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA8A 1.79 Active DFGin BLAminus in-in in-in ADP BEF Type1 Allosteric
Homo sapiens CDC7 CDC7_HUMAN Cell division cycle 7-related protein kinase 6YA6A 1.44 Active DFGin BLAminus in-in in-in 0SX BO3 Type1 Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha AF-O15111-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZA 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZB 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZC 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZD 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZE 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZF 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZG 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZH 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZI 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZJ 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZK 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5EBZL 4.5 Inactive DFGin BLAminus in-out in-out 5TL Type1
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQWA 5.6 Inactive None None in-in none-none No_ligand No_ligand
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQWB 5.6 Inactive None None in-in none-none No_ligand No_ligand
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQXA 5.4 Inactive None None in-out none-none No_ligand No_ligand
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQXB 5.4 Inactive None None in-out none-none No_ligand No_ligand
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQYA 5.2 Inactive None None in-out none-none No_ligand No_ligand
Homo sapiens CHUK IKKA_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit alpha 5TQYB 5.2 Inactive None None in-out none-none No_ligand No_ligand
Homo sapiens DSTYK DUSTY_HUMAN Dual serine/threonine and tyrosine protein kinase AF-Q6XUX3-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens EIF2AK1 E2AK1_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 1 AF-Q9BQI3-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 2A1AB 2.8 Inactive DFGin ABAminus in-in in-out No_ligand No_ligand
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 8QELB 2.451 Inactive DFGin ABAminus in-in in-out UH3 Type1
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 2A19B 2.5 Inactive DFGin ABAminus in-in in-out ANP Type1
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 2A19C 2.5 Inactive DFGin ABAminus in-in none-none ANP Type1
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase AF-P19525-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KA 2.6 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KB 2.6 None DFGin BLAminus in-in in-none ADP Type1
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3KC 2.6 Inactive DFGin BLAminus in-in in-out ADP Type1
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 6D3LA 3.1 Inactive DFGin None in-out in-none No_ligand No_ligand
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 3UIUA 2.903 Inactive DFGin None in-none in-none No_ligand No_ligand
Homo sapiens EIF2AK2 E2AK2_HUMAN Interferon-induced, double-stranded RNA-activated protein kinase 3UIUB 2.903 Inactive DFGin None in-none in-none No_ligand No_ligand
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 AF-Q9NZJ5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7OA 2.65 Inactive DFGin None out-out none-none 3Z6 Type1
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 7MF0AAA 2.809 Inactive DFGin None out-out none-none Z6P Type1
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 8EQ9AAA 2.86 Inactive DFGin None out-out none-none WPB Type1
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 8EQDAAA 2.92 Inactive DFGin None out-out out-none WPX Type1
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4G31A 2.28 Inactive DFGin None out-out none-out 0WH Type1.5_Back
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4G34A 2.7 Inactive DFGin None out-out none-out 924 Type1.5_Back
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4M7IA 2.34 Inactive DFGin None out-out none-out 27D Type1.5_Back
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 8EQEAAA 2.559 Inactive DFGin None out-out out-none WQ2 Type1.5_Back
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7JA 2.3 Inactive DFGout BBAminus out-out none-none 3Z1 Type1
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7KA 1.8 Inactive DFGout BBAminus out-out out-none 3Z3 Type2
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7LA 1.9 Inactive DFGout BBAminus out-out out-none 3Z4 Type2
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7NA 2.35 Inactive DFGout BBAminus out-out out-none 3Z5 Type2
Homo sapiens EIF2AK3 E2AK3_HUMAN Eukaryotic translation initiation factor 2-alpha kinase 3 4X7HA 2.0 Inactive DFGout None out-out none-none 3Z2 Type2
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 AF-Q9P2K8-K2A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3NA 3.01 None DFGin BLAminus out-out out-none KA4 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3OA 2.4 None DFGin BLAminus out-out out-none KA7 Type1.5_Back
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6A 2.8 Inactive DFGin None out-out none-out 38O Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6B 2.8 Inactive DFGin None out-out none-out 38O Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6C 2.8 Inactive DFGin None out-out out-out 38O Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QQ6D 2.8 Inactive DFGin None out-out out-none 38O Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKH 2.3 Inactive DFGinter BABtrans out-out out-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKF 2.3 Inactive DFGinter None out-out out-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKA 2.3 Inactive DFGout None out-none none-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKB 2.3 Inactive DFGout None out-out out-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKC 2.3 Inactive DFGout None out-out out-none G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKD 2.3 Inactive DFGout None out-out out-out G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKE 2.3 Inactive DFGout None out-none none-none G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 7QWKG 2.3 Inactive DFGout None out-out out-none G41 Type1
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LA 2.61 Inactive DFGout None in-in none-none KAV Type2
Homo sapiens EIF2AK4 E2AK4_HUMAN eIF-2-alpha kinase GCN2 6N3LB 2.61 Inactive DFGout None in-in none-none KAV Type2
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7HB 2.9 Inactive DFGin ABAminus in-in in-in 4L5 Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 AF-O75460-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 5HGIA 2.584 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDFB 2.54 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3BA 2.57 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CA 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CB 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CC 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3CD 2.3 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZCA 2.494 None DFGin BLAminus in-none in-in STU Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZCB 2.494 None DFGin BLAminus in-none in-in STU Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3KA 2.08 Active DFGin BLAminus in-in in-in SJS Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3EB 2.737 Inactive DFGin BLAminus out-out in-out SJV Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDFA 2.54 Inactive DFGin BLAminus out-out in-in N94 Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 7BMKA 1.85 Inactive DFGin BLAminus out-out in-in U4N Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 7BMKB 1.85 Inactive DFGin BLAminus out-out in-out U4N Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6URCA 2.2 Inactive DFGin BLAminus out-out in-in QFV Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6URCB 2.2 Inactive DFGin BLAminus out-out in-in QFV Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDDB 2.4 Inactive DFGin BLAminus in-out in-in N97 Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4U6RA 2.5 Inactive DFGin BLAminus out-out in-in 3E4 Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDBA 2.45 Inactive DFGin BLAminus out-out in-in N8S Type1.5_Back
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3EA 2.737 None DFGin BLAminus out-out none-none SJV Type1.5_Front
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6XDDA 2.4 Inactive DFGin BLAminus out-out in-out N97 Type1.5_Front
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDA 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDB 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZDC 3.102 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W39A 1.736 Inactive DFGin BLBplus in-in none-none SJG Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W39B 1.736 Inactive DFGin BLBplus in-in none-none SJG Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23A 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23B 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23C 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 3P23D 2.7 Inactive DFGin BLBplus out-out out-in ADP Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3AA 2.606 Inactive DFGin BLBplus in-in none-out SJM Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6W3AB 2.606 Inactive DFGin BLBplus in-out none-out SJM Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7GA 2.6 Inactive DFGin None in-in none-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7GB 2.6 Inactive DFGin None in-in none-in No_ligand No_ligand
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4Z7HA 2.9 Inactive DFGin None in-in in-in 4L5 Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9A 2.463 Inactive DFGout None out-out none-out 4K7 Type3
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9B 2.463 Inactive DFGout None out-out none-none 4K7 Type3
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 4YZ9C 2.463 Inactive DFGout None out-out none-none 4K7 Type3
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6HX1A 2.14 Inactive None None none-none out-out GXK Type1
Homo sapiens ERN1 ERN1_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE1 6HV0A 2.73 Inactive None None none-none out-out GUK Type1
Homo sapiens ERN2 ERN2_HUMAN Serine/threonine-protein kinase/endoribonuclease IRE2 AF-Q76MJ5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 5Y7ZA 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 5Y7ZB 2.804 Inactive DFGin ABAminus in-in in-in IRE Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4C57A 2.55 Inactive DFGin ABAminus in-out in-in FEF Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4C57B 2.55 Inactive DFGin ABAminus out-out in-in FEF Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4C59A 2.8 Inactive DFGin ABAminus in-in in-none FEF Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 5Y80A 2.5 Inactive DFGin ABAminus in-in in-out IRE IRE Type1 Allosteric
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4C58A 2.16 Inactive DFGin ABAminus in-in in-none 824 Type1.5_Back
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase AF-O14976-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4Y8DA 2.1 None DFGin BLAminus in-in in-none 49J Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4Y8DB 2.1 None DFGin BLAminus in-in in-none 49J Type1
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4O38A 2.097 Inactive None None in-in in-none No_ligand No_ligand
Homo sapiens GAK GAK_HUMAN Cyclin-G-associated kinase 4O38B 2.097 Inactive None None in-in in-none No_ligand No_ligand
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin AF-Q8TF76-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 2WB8A 2.15 Active DFGin BLAminus in-in in-none No_ligand No_ligand
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 5HTBA 1.7 Active DFGin BLAminus in-in in-none No_ligand No_ligand
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 5HTCA 1.5 Active DFGin BLAminus in-in in-none No_ligand No_ligand
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G39A 1.45 Active DFGin BLAminus in-in in-none 5ID Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 2VUWA 1.8 Active DFGin BLAminus in-in in-none 5ID Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3DLZA 1.85 Active DFGin BLAminus in-in in-none AMP Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3E7VA 2.0 Active DFGin BLAminus in-in in-none DZO Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3F2NA 1.8 Active DFGin BLAminus in-in in-none IZZ Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3FMDA 2.0 Active DFGin BLAminus in-in in-none IQB Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 3IQ7A 2.0 Active DFGin BLAminus in-in in-none 5ID Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 4OUCA 1.9 Active DFGin BLAminus in-in in-none 5ID Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 4QTCA 1.4 Active DFGin BLAminus in-in in-none 38Z Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G34A 1.76 Active DFGin BLAminus in-in in-none 5ID Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G35A 1.55 Active DFGin BLAminus in-in in-none EKK Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G36A 1.46 Active DFGin BLAminus in-in in-none EKH Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G37A 1.48 Active DFGin BLAminus in-in in-none FTU Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G38A 1.47 Active DFGin BLAminus in-in in-none TBN Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z57A 1.5 Active DFGin BLAminus in-in in-none Q8W Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z58A 1.8 Active DFGin BLAminus in-in in-none Q9B Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z59A 2.0 Active DFGin BLAminus in-in in-none Q98 Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5CA 1.75 Inactive DFGin BLAminus out-out in-none PQ5 Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5DA 1.75 Active DFGin BLAminus in-in in-none Q8Q Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5EA 1.5 Active DFGin BLAminus in-in in-none Q8K Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 7AVQA 1.65 Active DFGin BLAminus in-in in-none S1Z Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 7OPSA 2.38 Active DFGin BLAminus in-in in-none 07C Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 8RDKA 2.0 Active DFGin BLAminus in-in in-none YQT Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 7SQMA 1.78 Active DFGin BLAminus in-in in-none A5G Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6G3AA 1.43 Inactive DFGin BLAminus in-out in-none 5ID Type1
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z56A 1.9 Inactive DFGin BLAminus out-out in-none Q7Q Type1.5_Back
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5BA 1.9 Inactive DFGin BLAminus out-out in-none Q7Z Type1.5_Back
Homo sapiens HASPIN HASP_HUMAN Serine/threonine-protein kinase haspin 6Z5AA 1.55 Inactive DFGin BLAminus out-out in-none Q8B Type1.5_Front
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta AF-O14920-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CB 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CC 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CD 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CF 3.98 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKA 2.83 None DFGin BLAminus in-in none-out KSA Type1
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4KIKB 2.83 Active DFGin BLAminus in-in in-in KSA Type1
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CA 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand
Homo sapiens IKBKB IKKB_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit beta 4E3CE 3.98 Inactive DFGin None in-in in-out No_ligand No_ligand
Homo sapiens IKBKE IKKE_HUMAN Inhibitor of nuclear factor kappa-B kinase subunit epsilon AF-Q14164-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6O5ZA 2.285 Inactive DFGin BLAminus in-in out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JXUA 2.44 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JXUB 2.44 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7MONA 2.23 Inactive DFGin BLAplus out-out out-out ZL1 Type1
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4MWIA 1.7 Inactive DFGin BLBminus in-in out-out PXN Allosteric
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6BWKA 2.79 Inactive DFGin BLBminus in-none none-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JW7A 2.63 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 8SLZA 2.3 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4M67A 1.9 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK6A 2.41 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK5A 2.5 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KO1A 2.16 Inactive DFGin BLBminus in-in out-out 6UY Type1
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6O5ZB 2.285 Inactive DFGout None in-out none-out LN4 Type2
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KNJA 2.88 Inactive None None in-in none-out 6UX Type1
Homo sapiens MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KNJB 2.88 Inactive None None in-in none-out 6UX Type1
Homo sapiens MOS MOS_HUMAN Proto-oncogene serine/threonine-protein kinase mos AF-P00540-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens PBK TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase AF-Q96KB5-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens PBK TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase 5J0AA 2.74 Inactive DFGin BLBtrans out-out in-in No_ligand No_ligand
Homo sapiens PBK TOPK_HUMAN Lymphokine-activated killer T-cell-originated protein kinase 5J0AB 2.74 Inactive DFGin BLBtrans out-out in-in No_ligand No_ligand
Homo sapiens PDIK1L PDK1L_HUMAN Serine/threonine-protein kinase PDIK1L AF-Q8N165-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens PEAK1 PEAK1_HUMAN Inactive tyrosine-protein kinase PEAK1 6BHCA 2.3 None DFGin BLAminus out-none in-out No_ligand No_ligand
Homo sapiens PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SORA 3.96 Inactive DFGin BLBminus out-out out-out ADP Type1
Homo sapiens PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SRQW 6.2 Inactive None None out-none out-out No_ligand No_ligand
Homo sapiens PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 7BL1CCC 9.8 Inactive None None out-none out-out No_ligand No_ligand
Homo sapiens PINK1 PINK1_HUMAN Serine/threonine-protein kinase PINK1, mitochondrial AF-Q9BXM7-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens PKDCC PKDCC_HUMAN Extracellular tyrosine-protein kinase PKDCC AF-Q504Y2-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase AF-Q99640-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 3P1AA 1.7 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCVA 1.92 Active DFGin BLAminus in-in in-in 1N1 Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCWA 2.25 Active DFGin BLAminus in-in in-in 93J Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCWB 2.25 Inactive DFGin BLAminus in-out in-in 93J Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCXA 2.7 Active DFGin BLAminus in-in in-in H8H Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCYA 1.56 Active DFGin BLAminus in-in in-in DB8 Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VCZA 1.5 Active DFGin BLAminus in-in in-in XZN Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD0A 2.13 Active DFGin BLAminus in-in in-in 8X7 Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD1A 1.7 Active DFGin BLAminus in-in in-in P48 Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 5VD3A 1.8 Active DFGin BLAminus in-in in-in H8H Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6CA 2.2 Active DFGin BLAminus in-in in-in QGR Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6CB 2.2 Active DFGin BLAminus in-in in-in QGR Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6DB 2.35 Active DFGin BLAminus in-in in-in QGY Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6EB 2.15 Active DFGin BLAminus in-in in-in QGI Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8WJYA 1.88 Active DFGin BLAminus in-in in-in W9X Type1
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6DA 2.35 Active DFGin BLAminus in-in in-in QGY Type1.5_Back
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6EA 2.15 Active DFGin BLAminus in-in in-in QGI Type1.5_Back
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6FA 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back
Homo sapiens PKMYT1 PMYT1_HUMAN Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 8D6FB 2.49 Active DFGin BLAminus in-in in-in QG5 Type1.5_Back
Homo sapiens PRAG1 PRAG1_HUMAN Inactive tyrosine-protein kinase PRAG1 5VE6A 2.953 Inactive None None none-none none-none No_ligand No_ligand
Homo sapiens RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAUC 2.6 Active DFGin BLAminus in-in in-none ADP Type1
Homo sapiens RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAVB 2.1 Active DFGin BLAminus in-in in-none ACP Type1
Homo sapiens RNASEL RN5A_HUMAN 2-5A-dependent ribonuclease 4OAVD 2.1 Active DFGin BLAminus in-in in-none ACP Type1
Homo sapiens SBK1 SBK1_HUMAN Serine/threonine-protein kinase SBK1 AF-Q52WX2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens SBK2 SBK2_HUMAN Serine/threonine-protein kinase SBK2 AF-P0C263-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens SBK3 SBK3_HUMAN Uncharacterized serine/threonine-protein kinase SBK3 AF-P0C264-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens STK16 STK16_HUMAN Serine/threonine-protein kinase 16 AF-O75716-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens STK16 STK16_HUMAN Serine/threonine-protein kinase 16 2BUJA 2.6 Active DFGin BLAminus in-in in-in STU STU Type1 Allosteric
Homo sapiens STK16 STK16_HUMAN Serine/threonine-protein kinase 16 2BUJB 2.6 Active DFGin BLAminus in-in in-in STU STU Type1 Type1
Homo sapiens STK35 STK35_HUMAN Serine/threonine-protein kinase 35 AF-Q8TDR2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens STK36 STK36_HUMAN Serine/threonine-protein kinase 36 AF-Q9NRP7-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 AF-Q9UHD2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUUA 1.8 Active DFGin BLAminus in-in in-in BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUUB 1.8 Active DFGin BLAminus in-in in-in BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUTA 2.6 Inactive DFGin BLAminus in-in in-out BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4EUTB 2.6 Inactive DFGin BLAminus in-in in-out BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IW0A 4.0 Active DFGin BLAminus in-in in-in BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6O8BA 3.4 Inactive DFGin BLAminus out-out in-in BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6O8BB 3.4 Inactive DFGin BLAminus in-in out-in BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6NT9A 3.3 Inactive DFGin BLBplus out-out none-out No_ligand No_ligand
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6NT9B 3.3 Inactive DFGin BLBplus out-out none-out No_ligand No_ligand
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 5W5VA 3.645 Inactive DFGin BLBplus out-out none-none ANW Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6BODA 3.197 Inactive DFGin BLBplus out-out out-none E0P Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6RSTA 3.29 Inactive DFGin BLBplus out-out out-in KHQ Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IWOA 2.61 Inactive DFGin BLBplus out-out out-in 1H4 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IM0A 2.4 Inactive DFGin BLBplus out-out none-none 1FV Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IM2A 2.5 Inactive DFGin BLBplus out-out none-none BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IM3A 3.342 Inactive DFGin BLBplus out-out none-none BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6BNYA 3.341 Inactive DFGin None out-out none-none E0M Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6BOEA 3.598 Inactive DFGin None out-out none-in E0S Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6CQ0A 3.19 Inactive DFGin None out-out none-out F8M Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6CQ4A 3.2 Inactive DFGin None out-out none-in F8P Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6CQ5A 3.354 Inactive DFGin None out-out none-none F8S Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6RSRA 3.15 Inactive DFGin None out-out out-in KHT Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 6RSUA 2.75 Inactive DFGin None out-out out-in KJB Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IWPA 3.065 Inactive DFGin None out-out out-in BX7 Type1
Homo sapiens TBK1 TBK1_HUMAN Serine/threonine-protein kinase TBK1 4IWQA 3.0 Inactive DFGin None out-out out-in 1FV Type1
Homo sapiens TLK1 TLK1_HUMAN Serine/threonine-protein kinase tousled-like 1 AF-Q9UKI8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens TLK2 TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 AF-Q86UE8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens TLK2 TLK2_HUMAN Serine/threonine-protein kinase tousled-like 2 5O0YA 2.86 Inactive DFGin BLAminus out-out in-in AGS Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK AF-Q96S44-K1A -1.0 Active DFGin BLAminus in-in in-none No_ligand No_ligand
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZAA 1.9 Active DFGin BLAminus in-in in-none DUI Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZAC 1.9 Active DFGin BLAminus in-in in-none DUI Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZBA 2.02 Active DFGin BLAminus in-in in-none DQ4 Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZBC 2.02 Active DFGin BLAminus in-in in-none DQ4 Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZCA 1.71 Active DFGin BLAminus in-in in-none DO0 Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZCC 1.71 Active DFGin BLAminus in-in in-none DO0 Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZDA 2.05 Active DFGin BLAminus in-in in-none DVO Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 7SZDC 2.05 Active DFGin BLAminus in-in in-none DVO Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 6WQXC 2.53 Active DFGin BLAminus in-in in-none ANP Type1
Homo sapiens TP53RK PRPK_HUMAN EKC/KEOPS complex subunit TP53RK 6WQXD 2.53 Active DFGin BLAminus in-in in-none ANP Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3CEKA 2.3 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3DBQA 2.7 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 2ZMCA 3.14 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6GVJA 2.41 Inactive DFGin ABAminus out-out out-out No_ligand No_ligand
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5NTTA 2.75 Inactive DFGin ABAminus out-out out-out SVE Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5LJJA 3.0 Inactive DFGin ABAminus out-out out-out AD5 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5MRBA 2.2 Inactive DFGin ABAminus out-out out-out C5N Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EH0A 2.18 Inactive DFGin ABAminus out-out out-out 5NW Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6H3KA 2.48 Inactive DFGin ABAminus out-out out-none FMW Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4JS8A 1.94 Inactive DFGin ABAminus in-out out-out 1PF Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4JT3A 2.2 Inactive DFGin ABAminus out-out out-out 1PH Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4O6LA 2.38 Inactive DFGin ABAminus out-out out-none 2QK Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4O6LB 2.38 Inactive DFGin ABAminus out-out out-out 2QK Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4ZEGA 2.33 Inactive DFGin ABAminus in-in out-none 052 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7CILA 2.3 Inactive DFGin ABAminus in-in out-out FZR Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7CHNA 2.4 Inactive DFGin ABAminus in-out out-out FZL Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7CHTA 2.4 Inactive DFGin ABAminus in-in out-none FZO Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7CJAA 2.49 Inactive DFGin ABAminus in-in out-out G0U Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7CLHA 2.9 Inactive DFGin ABAminus out-out out-out G5C Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4D2SA 2.5 Inactive DFGin ABAminus out-out none-none DYK Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6TN9A 2.6 Inactive DFGin ABAminus in-out out-out NN5 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6TNCA 2.3 Inactive DFGin ABAminus in-in out-out O23 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6N6OA 2.6 Inactive DFGin ABAminus out-out out-none KE7 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3GFWA 2.74 Inactive DFGin ABAminus out-out none-out S22 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4BHZA 2.85 Inactive DFGin ABAminus out-out out-out Z0B Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4BI0A 2.84 Inactive DFGin ABAminus out-out out-out Z0W Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4BI1A 2.7 Inactive DFGin ABAminus out-out out-out ZO6 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4BI2A 3.11 Inactive DFGin ABAminus out-out out-out ZO8 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4EA 2.6 Inactive DFGin ABAminus out-out out-out 4T9 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4FA 2.36 Inactive DFGin ABAminus out-out out-out 7CE Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4GA 2.65 Inactive DFGin ABAminus out-out none-out 7RO Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4HA 2.8 Inactive DFGin ABAminus out-out none-none 7RO Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4IA 2.65 Inactive DFGin ABAminus out-out out-none X20 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4C4JA 2.5 Inactive DFGin ABAminus in-in out-out X21 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4CV8A 3.0 Inactive DFGin ABAminus out-none out-out 3D7 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4CV9A 2.5 Inactive DFGin ABAminus out-out out-out W2K Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 4CVAA 2.5 Inactive DFGin ABAminus out-out out-out WBI Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP0A 2.15 Inactive DFGin ABAminus out-out out-out AU5 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP1A 2.05 Inactive DFGin ABAminus in-out out-out O38 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP2A 2.8 Inactive DFGin ABAminus in-in out-out PWU Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EHLA 2.66 Inactive DFGin ABAminus out-none out-out 0SQ Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EHOA 2.18 Inactive DFGin ABAminus out-out out-out 5O1 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EHYA 2.26 Inactive DFGin ABAminus out-out out-out 5O4 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EI2A 2.67 Inactive DFGin ABAminus out-out out-out 5O7 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EI6A 2.01 Inactive DFGin ABAminus in-out out-out 5OQ Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5EI8A 2.17 Inactive DFGin ABAminus out-out out-out 5OE Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5N87A 2.29 Inactive DFGin ABAminus out-out out-out N66 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP6A 2.1 Inactive DFGin ABAminus in-in out-out PWU Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP7A 2.45 Inactive DFGin ABAminus out-out out-out SVE Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5O91A 3.2 Inactive DFGin ABAminus out-out out-out C5N Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6B4WA 2.9 Inactive DFGin ABAminus in-none out-out CQ7 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 2X9EA 3.1 Inactive DFGin ABAminus out-out out-out SVE Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3VQUA 2.4 Inactive DFGin ABAminus out-out out-out O22 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3WYXA 2.9 Inactive DFGin ABAminus in-out out-out O38 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3WYYA 3.05 Inactive DFGin ABAminus in-out out-out O17 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5N7VA 2.52 Inactive DFGin ABAminus out-out out-out 8PT Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5N84A 2.3 Inactive DFGin ABAminus out-out out-out 8Q5 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5N93A 2.1 Inactive DFGin ABAminus out-out out-out 8QE Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5NA0A 2.9 Inactive DFGin ABAminus out-out out-out 8QZ Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMNA 2.7 Inactive DFGin ABAminus out-out out-out ATP Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMOA 2.4 Inactive DFGin ABAminus out-out out-out STU Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3HMPA 2.3 Inactive DFGin ABAminus out-out out-out CX4 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP3A 2.7 Inactive DFGin ABAminus out-out out-out AU5 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP4A 2.85 Inactive DFGin ABAminus out-out out-out O38 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 2ZMDA 2.88 Inactive DFGin ABAminus out-out out-out 537 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7LQDA 1.95 Inactive DFGin ABAminus out-out out-out YB4 TOE Type1 Allosteric
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5AP5A 2.8 Inactive DFGin ABAminus out-out none-out 7RO 1KA Type1 Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6TNDA 2.58 Inactive DFGin ABAminus in-in out-none 8RH Type1.5_Back
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3W1FA 2.7 Inactive DFGin ABAminus in-in out-out 1O5 Type1.5_Back
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3WZJA 2.75 Inactive DFGin ABAminus in-in out-out O43 Type1.5_Back
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3WZKA 2.3 Inactive DFGin ABAminus in-in out-out O23 Type1.5_Back
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5NADA 2.8 Inactive DFGin ABAminus in-in out-none 8RH Type1.5_Back
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 6TNBA 2.65 Inactive DFGin ABAminus out-out out-out 8QW Type1.5_Front
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 5N9SA 2.3 Inactive DFGin ABAminus out-out out-out 8QW Type1.5_Front
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK AF-P33981-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 3H9FA 2.6 Inactive DFGin BLAplus in-none out-out 92M Type1
Homo sapiens TTK TTK_HUMAN Dual specificity protein kinase TTK 7CHMA 2.65 Inactive DFGin None in-in out-out FZF Type1
Homo sapiens UHMK1 UHMK1_HUMAN Serine/threonine-protein kinase Kist AF-Q8TAS1-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 AF-O75385-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6MNHA 1.73 Inactive DFGin BLAminus in-in in-out JVD Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 8SV9A 2.3 Active DFGin BLAminus in-in in-in WXH Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 8SV9B 2.3 Active DFGin BLAminus in-in in-in WXH Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNOA 1.56 Active DFGin BLAminus in-in in-in 3RF Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPA 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPB 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPC 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 4WNPD 1.88 Active DFGin BLAminus in-in in-in 3RJ Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 5CI7A 1.74 Active DFGin BLAminus in-in in-in 51W Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6QASA 1.75 Active DFGin BLAminus in-in in-in 34W Type1
Homo sapiens ULK1 ULK1_HUMAN Serine/threonine-protein kinase ULK1 6QASB 1.75 Active DFGin BLAminus in-in in-in 34W 34W Type1 Allosteric
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 AF-Q8IYT8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATA 2.77 None DFGin BLAminus out-out in-none FE7 Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATB 2.77 None DFGin BLAminus out-out in-none FE7 Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATC 2.77 None DFGin BLAminus out-out in-none FE7 Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QATD 2.77 None DFGin BLAminus in-out in-none FE7 Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAUA 2.48 Inactive DFGin BLAminus in-in in-out 1FV Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAUB 2.48 None DFGin BLAminus in-in in-none 1FV Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAUC 2.48 None DFGin BLAminus in-in in-none 1FV Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVA 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVB 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVC 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6QAVD 2.05 Inactive DFGin BLAminus in-in in-out HVH Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDA 2.7 None DFGin BLAminus out-out in-none EDJ Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDB 2.7 None DFGin BLAminus in-out in-none EDJ Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDC 2.7 None DFGin BLAminus out-out in-none EDJ Type1
Homo sapiens ULK2 ULK2_HUMAN Serine/threonine-protein kinase ULK2 6YIDD 2.7 None DFGin BLAminus out-out in-none EDJ Type1
Homo sapiens ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 AF-Q6PHR2-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDYU 1.7 Inactive DFGin BLAminus out-out in-in DB8 DB8 Type1 Allosteric
Homo sapiens ULK3 ULK3_HUMAN Serine/threonine-protein kinase ULK3 6FDZU 2.55 Inactive DFGout BBAminus out-out out-out C87 Type1
Homo sapiens ULK4 ULK4_HUMAN Serine/threonine-protein kinase ULK4 6U5LA 1.75 Inactive DFGin ABAminus out-none in-in 3RJ Type1
Homo sapiens ULK4 ULK4_HUMAN Serine/threonine-protein kinase ULK4 6TSZU 1.9 Inactive DFGin ABAminus out-none in-in AGS Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase AF-P30291-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 2Z2WA 2.22 Active DFGin BLAminus in-in in-in 770 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 7N3UA 2.65 Inactive DFGin BLAminus out-out in-in 05J Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 8BJUA 1.53 Inactive DFGin BLAminus in-out in-in QT9 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 2IN6A 1.9 Active DFGin BLAminus in-in in-in 839 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 2IO6A 2.2 Active DFGin BLAminus in-in in-in 330 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 3BI6A 2.2 Inactive DFGin BLAminus in-out in-in 396 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 3BIZA 2.2 Active DFGin BLAminus in-in in-in 61E Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 3CQEA 2.5 Inactive DFGin BLAminus in-out in-in P91 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 3CR0A 2.3 Inactive DFGin BLAminus in-out in-in 809 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5V5YA 1.9 Active DFGin BLAminus in-in in-in 8X7 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC3A 1.97 Inactive DFGin BLAminus out-out in-in DB8 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC4A 2.1 Inactive DFGin BLAminus in-out in-in XZN Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC5A 1.93 Inactive DFGin BLAminus in-out in-in 96M Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VC6A 2.0 Active DFGin BLAminus in-in in-in P48 Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD2A 2.05 Inactive DFGin BLAminus out-out in-in 34W Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD4A 2.02 Active DFGin BLAminus in-in in-in 99J Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD5A 2.05 Active DFGin BLAminus in-in in-in 99M Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD7A 2.08 Active DFGin BLAminus in-in in-in 99V Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD8A 1.85 Active DFGin BLAminus in-in in-in 98M Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VD9A 1.87 Inactive DFGin BLAminus in-out in-in 98G Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 5VDAA 2.1 Inactive DFGin BLAminus in-out in-in 98D Type1
Homo sapiens WEE1 WEE1_HUMAN Wee1-like protein kinase 1X8BA 1.81 Active DFGin BLAminus in-in in-in 824 Type1
Homo sapiens WEE2 WEE2_HUMAN Wee1-like protein kinase 2 AF-P0C1S8-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Homo sapiens WEE2 WEE2_HUMAN Wee1-like protein kinase 2 5VDKA 2.7 Active DFGin BLAminus in-in in-in 8X7 Type1
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 AF-Q9H4A3-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYA 2.458 None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WDYB 2.458 None DFGin BLAminus out-none in-none ANP A6S Type1 Type3
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8A 2.006 Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5WE8B 2.006 Inactive DFGin BLAminus out-none in-out ANP A7Y Type1 Type3
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9A 2.5 Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 5TF9B 2.5 Inactive DFGin BLAminus out-none in-out 7AV ANP Type3 Type1
Homo sapiens WNK1 WNK1_HUMAN Serine/threonine-protein kinase WNK1 4PWNA 1.84 Inactive DFGin None out-none out-none No_ligand No_ligand
Homo sapiens WNK2 WNK2_HUMAN Serine/threonine-protein kinase WNK2 AF-Q9Y3S1-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 AF-Q9BYP7-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O21A 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O21B 2.06 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 8EDHC 3.111 None DFGin BLAminus out-none out-none No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O26A 2.379 Active DFGin BLAminus out-none in-in ANP Type1
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O26B 2.379 Active DFGin BLAminus out-none in-in ANP Type1
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 8EDHA 3.111 None DFGin BLAminus out-none out-none WGK Type1
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VA 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VB 1.723 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2CA 2.4 Inactive DFGin BLBminus out-none out-in No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2BB 2.038 Inactive DFGin BLBminus out-none out-none KS1 Type1
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2BA 2.038 Inactive DFGin BLBtrans out-none out-out KS1 Type1
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O23A 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand
Homo sapiens WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O23B 2.25 Inactive DFGin None out-none out-out No_ligand No_ligand
Homo sapiens WNK4 WNK4_HUMAN Serine/threonine-protein kinase WNK4 AF-Q96J92-K1A -1.0 Active DFGin BLAminus out-none in-in No_ligand No_ligand
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBA 3.05 Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBB 3.05 Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9A 2.67 Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9B 2.67 Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHA 3.6 Inactive DFGin None in-in in-none TBR TBR TBR Allosteric Allosteric Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHB 3.6 Inactive DFGin None in-in in-none TBR TBR TBR TBR Allosteric Allosteric Allosteric Allosteric
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVIA 2.2 Inactive DFGin ABAminus in-in in-in YFY Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVHA 2.65 Active DFGin BLAminus in-in in-in YFS Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVHB 2.65 Active DFGin BLAminus in-in in-in YFV Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVIB 2.2 Active DFGin BLAminus in-in in-in YFV Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ6A 2.132 Active DFGin BLAminus in-in in-in YFV Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ6B 2.132 Active DFGin BLAminus in-in in-in 5OI Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ7A 2.124 Active DFGin BLAminus in-in in-in 5P6 Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ7B 2.124 Active DFGin BLAminus in-in in-in 5P6 Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8A 2.59 Active DFGin BLAminus in-in in-in 5QI PG6 Type1 Allosteric
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8B 2.59 Active DFGin BLAminus in-in in-in YFV PG6 Type1 Allosteric
Mus musculus EIF2AK3 E2AK3_MOUSE Eukaryotic translation initiation factor 2-alpha kinase 3 3QD2B 2.81 Inactive DFGin None in-in in-none No_ligand No_ligand
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3A 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3B 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4A 3.0 Inactive DFGin BLBplus out-out out-in 31K ADP Allosteric Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5A 3.4 Inactive DFGin BLBplus out-out out-in 31L ADP PEU Allosteric Type1 Allosteric
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4B 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4C 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4D 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5B 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5C 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5D 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus MLKL MLKL_MOUSE Mixed lineage kinase domain-like protein 4M68A 1.696 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
Mus musculus MLKL MLKL_MOUSE Mixed lineage kinase domain-like protein 4BTFA 2.604 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
Mus musculus MLKL MLKL_MOUSE Mixed lineage kinase domain-like protein 4M69B 2.497 Inactive None None out-out out-out No_ligand No_ligand
Mus musculus POMK SG196_MOUSE Protein O-mannose kinase 5GZ8A 2.5 Inactive DFGin ABAminus none-none in-out No_ligand No_ligand
Mus musculus POMK SG196_MOUSE Protein O-mannose kinase 5GZ9A 2.4 Inactive DFGin ABAminus none-none in-out ANP MAN Type1 Allosteric
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 4JL9A 3.1 Inactive DFGin BLAplus out-out out-out BX7 Type1
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 4JLCA 3.0 Inactive DFGin BLAplus out-out out-out SU6 Type1
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 6O8CA 3.17 Inactive DFGin BLBplus out-out none-none BX7 Type1
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 6O8CB 3.17 Inactive DFGin BLBplus out-out none-out BX7 Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QB 2.88 Inactive DFGin BLAminus in-in in-out CJJ Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QC 2.88 Inactive DFGin BLAminus in-in in-out CJJ Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QD 2.88 Inactive DFGin BLAminus in-in in-out CJJ Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QA 2.88 Inactive DFGin BLAminus in-in in-out CJJ 0BD Type1 Allosteric
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4OW8A 2.03 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FA 2.9 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FB 2.9 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FC 2.9 Inactive DFGin BLBminus out-none none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 1MRUA 3.0 Inactive DFGin ABAminus in-in in-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 1MRUB 3.0 Inactive DFGin ABAminus in-in in-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 6B2PA 3.01 None DFGin BLAminus in-in none-none CJJ Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 1O6YA 2.2 None DFGin BLAminus in-in in-none ACP Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMA 2.89 Inactive DFGin BLAminus in-in in-out MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMB 2.89 Inactive DFGin BLAminus in-in in-out MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMD 2.89 None DFGin BLAminus in-in none-out MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 5U94A 2.2 Active DFGin BLAminus in-in in-in G93 Type1.5_Back
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F61A 1.8 Inactive DFGin BLBminus in-out none-none ADP Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIA 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIB 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIC 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORID 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORKA 1.6 Inactive DFGin BLBminus in-out none-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORLA 2.9 Inactive DFGin BLBminus in-out none-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORPA 2.1 Inactive DFGin BLBminus out-out none-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORTA 1.9 Inactive DFGin BLBminus out-out out-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORMA 2.5 Inactive DFGin BLBminus in-out out-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3OROA 1.9 Inactive DFGin BLBminus in-out out-out AGS NHE Type1 Allosteric
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMC 2.89 Inactive DFGin None in-out none-none MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F69A 2.8 Inactive None None in-out out-none XDR Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F69B 2.8 Inactive None None in-out out-out XDR Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 6I2PA 2.37 Inactive None None in-out out-out ACP Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 6I2PB 2.37 Inactive None None in-out none-none ACP Type1
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34A 2.8 Inactive DFGout None out-out none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34B 2.8 Inactive DFGout None out-out none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAA 2.75 Inactive DFGin None out-none none-none V17 Type1
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAB 2.75 Inactive DFGin None out-none none-out V17 Type1
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAC 2.75 Inactive DFGin None out-none none-none V17 Type1
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAD 2.75 Inactive DFGin None out-none none-none V17 Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 7Q52AAA 2.35 Inactive DFGin ABAminus out-out in-in FE 8ZC Allosteric Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 2PZIA 2.4 Inactive DFGin ABAminus out-out in-in AXX Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 2PZIB 2.4 Inactive DFGin ABAminus out-out in-in AXX Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 4Y0XA 1.74 Inactive DFGin BLAminus out-out in-in ADP Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 4Y12A 1.9 None DFGin BLAminus out-none in-in AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWKA 3.3 Inactive DFGin None out-none out-none AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWKB 3.3 Inactive DFGin None out-none out-none AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4CZYB 3.4 Inactive DFGin None out-none out-none ANP Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4CZYD 3.4 Inactive DFGin None out-none out-none ANP Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWXA 2.85 Inactive DFGin None out-none out-none AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWXB 2.85 Inactive DFGin None out-none out-none AGS Type1
Oryza sativa FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUPA 1.98 Inactive DFGin BLAminus in-in in-out ATP Type1
Oryza sativa FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUVA 2.09 Inactive DFGin BLAminus in-in in-out ADP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 6EQIC 3.1 Inactive DFGin ABAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4KA 3.25 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4KB 3.25 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4LA 3.28 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4LB 3.28 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYFA 2.75 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYFB 2.75 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MA 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MB 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MC 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MD 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4ME 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MF 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MG 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MH 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MI 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MJ 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MK 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4ML 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4NA 2.35 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4NB 2.35 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYHA 2.84 Active DFGin BLAminus in-in in-in ANP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYHB 2.84 Active DFGin BLAminus in-in in-in ANP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIA 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIB 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T3XA 3.53 Inactive DFGin None in-in in-in No_ligand No_ligand
Plasmodium falciparum PK7 O96214_PLAFA mitogen-activated protein kinase kinase 2PMLX 2.6 Inactive DFGin BLAminus out-out in-in ANP Type1
Plasmodium falciparum PK7 Q7YTF7_PLAF7 mitogen-activated protein kinase kinase 2PMNX 2.8 Inactive DFGin BLAminus in-out in-in K51 Type1
Plasmodium falciparum PK7 Q7YTF7_PLAF7 mitogen-activated protein kinase kinase 2PMOX 2.9 Active DFGin BLAminus in-in in-in HMD Type1
Rattus norvegicus MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZA 2.192 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand
Rattus norvegicus MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZB 2.192 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand
Rattus norvegicus PRAG1 PRAG1_RAT Inactive tyrosine-protein kinase PRAG1 6EWXB 2.771 None DFGin BLAminus none-none in-out No_ligand No_ligand
Rattus norvegicus PRAG1 PRAG1_RAT Inactive tyrosine-protein kinase PRAG1 6EWXA 2.771 Inactive None None none-none in-none No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6CN9A 1.8 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 4Q2AA 3.5 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6CN9B 1.8 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 7UOSA 2.9 Inactive DFGin BLBminus out-none out-out WIB Type1
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6OL2A 2.1 Inactive DFGin BLBminus out-none out-out MU7 Type1.5_Back
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 5W7TA 2.01 Inactive DFGin BLBtrans out-none out-in ANP Type1
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 5W7TB 2.01 Inactive DFGin BLBtrans out-none out-in ANP Type1
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 5DRBA 1.65 Inactive DFGin BLBtrans out-none out-out 5FJ Type1.5_Front
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WWAA 2.953 None DFGin BLAminus in-none in-none No_ligand No_ligand
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW7A 1.669 Active DFGin BLAminus in-in in-none AMP Type1
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW9A 1.951 Active DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW5A 1.997 Active DFGin BLAminus in-in in-none ANP Type1.5_Front
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7PT68 3.2 Inactive DFGin ABAminus in-in in-in AGS Type1
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7PT6H 3.2 Inactive DFGin ABAminus in-in in-in AGS Type1
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7PT78 3.8 Inactive DFGin ABAminus in-out in-in ADP BEF Type1 Allosteric
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7V3VH 2.9 Active DFGin BLAminus in-in in-in AGS Type1
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7P5Z1 3.3 Inactive DFGin BLAplus in-out in-in No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4A 1.95 Inactive DFGin BLBminus out-out out-none No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4B 1.95 Inactive DFGin BLBminus out-out none-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCA 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCB 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCC 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCD 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEA 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEB 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEC 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXED 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEE 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEF 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5A 2.0 Inactive DFGin BLBminus out-out out-none ANP Type1
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5B 2.0 Inactive DFGin BLBminus out-out none-out ANP Type1
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDA 2.75 Inactive DFGin BLBminus out-out out-out ATP Type1
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDB 2.75 Inactive DFGin BLBminus out-out none-out ATP Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2A 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2B 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMA 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMB 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMC 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMD 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDME 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMF 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMG 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVA 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVB 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVC 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVD 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVE 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVF 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVG 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVH 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVI 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVJ 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVK 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVL 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVM 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVN 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJA 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJB 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJC 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJD 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJE 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJF 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJG 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJH 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJI 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJJ 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJK 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJL 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJM 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJN 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOA 2.4 None DFGin BLAminus out-in in-none ADP Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOB 2.4 None DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ1A 3.33 None DFGin BLAminus in-in in-none DKI Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ1B 3.33 None DFGin BLAminus in-in in-none DKI Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0A 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0B 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae VPS15 VPS15_YEAST Serine/threonine-protein kinase VPS15 5KC2B 28.0 Inactive None None out-none none-none No_ligand No_ligand
Saccharomyces cerevisiae VPS15 VPS15_YEAST Serine/threonine-protein kinase VPS15 5DFZB 4.4 Inactive None None out-none none-none No_ligand No_ligand
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1RA 1.6 Inactive DFGin ABAminus in-out out-out No_ligand No_ligand
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5HNVA 1.41 Inactive DFGin ABAminus in-out out-out ATP Type1
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1QA 1.602 Inactive DFGin ABAminus in-out out-out ATP Type1
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1SA 1.45 Inactive DFGin ABAminus in-out out-out ACP Type1
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1TA 1.55 Inactive DFGin ABAminus in-out out-out ADP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMA 3.0 None DFGin BLAminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMD 3.0 None DFGin BLAminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQME 3.0 None DFGin BLAminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMB 3.0 Inactive DFGin BLBminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMC 3.0 Inactive DFGin BLBminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMF 3.0 Inactive DFGin None out-out out-none ANP Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OA 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OB 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OC 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OD 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PA 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PB 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PC 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PD 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M11a 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M11b 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M12b 2.4 Active DFGin BLAminus in-in in-none 25L J60 Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DSYa 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DSYb 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DTSa 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DTSb 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7ELWa 3.55 Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7ELWb 3.55 Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M12a 2.4 Active DFGin BLAminus in-in in-none J60 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M13a 2.56 Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M13b 2.56 Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5YJ9D 2.53 Inactive DFGin ABAminus in-in in-in ANP Type1
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATA 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATB 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATC 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATD 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATE 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATF 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 7MP8A 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 7MP9A 2.8 Inactive DFGin None in-in in-in AN2 Type1
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3RZFA 4.0 Inactive DFGin BLAminus in-in in-out XNM Type1
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8A 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8B 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8C 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8D 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8E 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8F 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8G 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8H 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Zea mays DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6CPYA 1.7 Inactive DFGout BBAminus in-none out-none No_ligand No_ligand
Zea mays DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6CPYB 1.7 Inactive DFGout BBAminus out-none out-none No_ligand No_ligand
Zea mays DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6EASA 2.0 Inactive DFGout BBAminus out-none out-none J3A Type1
Zea mays SIRK1 K7VIQ3_MAIZE Putative leucine-rich repeat protein kinase family protein 5UV4A 2.3 Inactive DFGin BLBplus out-out out-out ANP Type1

OTHER kinases in all conformations in complex with All ligands

Total number of genes: 35
Total number of chains: 300
Spatial Label Dihedral Label Chains Representative
DFGin BLAminus 135 4Y0XA
DFGin BLAplus 6 4JLCA
DFGin ABAminus 28 7Q52AAA
DFGin BLBminus 43 6CN9B
DFGin BLBplus 13 5UV4A
DFGin BLBtrans 3 5DRBA
DFGin None 36 5GZAA
DFGinter None 2 7MXKA
DFGout BBAminus 3 6CPYA
DFGout None 15 4I93A
None None 16 3F69B
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Gene UniprotID Protein PDB Reso Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Arabidopsis thaliana BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68A 2.0 Inactive DFGin BLBminus out-out out-in PDO Allosteric
Arabidopsis thaliana BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68B 2.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I92A 1.6 Inactive DFGout None out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93A 1.5 Inactive DFGout None out-out out-out No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I93B 1.5 Inactive DFGout None out-out out-none No_ligand No_ligand
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94A 1.8 Inactive DFGout None out-out out-out ANP Type1
Arabidopsis thaliana BSK8 BSK8_ARATH Serine/threonine-protein kinase BSK8 4I94B 1.8 Inactive DFGout None out-out out-out ANP Type1
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAA 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAB 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAC 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL2 Q9FGG5_ARATH Protein kinase family protein 6LBAD 4.1 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4A 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4B 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4C 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana MLKL3 Q9LMN2_ARATH F22L4.1 protein 6KA4D 3.4 Inactive None None none-none out-none No_ligand No_ligand
Arabidopsis thaliana T1N2412 Q94K14_ARATH non-specific serine/threonine protein kinase 8K20B 3.7 Inactive DFGin BLAminus in-out in-none No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TB 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TE 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TH 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TK 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5TN 3.4 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5UB 3.9 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5VB 4.25 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J6IB 3.7 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Arabidopsis thaliana ZRK1 ZRK1_ARATH Serine/threonine-protein kinase ZRK1 6J5WB 3.7 Inactive DFGin BLAplus in-in out-none No_ligand No_ligand
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIA 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIB 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIC 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYID 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIE 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIF 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIG 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYIH 2.42 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJA 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJB 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJC 2.59 Inactive DFGin None out-none out-none ATP Type1
Chaetomium thermophilum PAN3 PAN3_CHATD PAN2-PAN3 deadenylation complex subunit PAN3 4CYJD 2.59 Inactive DFGin None out-none out-none ATP Type1
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXJA 1.92 Inactive DFGinter None out-out in-in MAP Type1
Corynebacterium glutamicum PKNG Q8NM29_CORGL Serine/threonine protein kinases 7MXKA 1.99 Inactive DFGinter None out-out in-in MAP Type1
Cydia pomonella granulosis virus PK1 A0A097P1P8_GVCP PK-1 6VVGA 2.01 Inactive DFGin BLAminus out-out in-in AMP Type1
Cydia pomonella granulosis virus PK1 A0A097P1P8_GVCP PK-1 6VVGB 2.01 Inactive DFGin BLAminus out-out in-in AMP Type1
Danio rerio POMK SG196_DANRE Protein O-mannose kinase 5GZAA 2.0 Inactive DFGin None none-none in-out ADP ZZ1 Type1 Allosteric
Drosophila melanogaster BUBR1 A1Z6I7_DROME Bub1-related kinase 6JKKA 1.85 Active DFGin BLAminus in-in in-out No_ligand No_ligand
Drosophila melanogaster BUBR1 A1Z6I7_DROME Bub1-related kinase 6JKMA 1.95 Active DFGin BLAminus in-in in-out ADP Type1
Drosophila melanogaster PAN3 PAN3_DROME PAN2-PAN3 deadenylation complex subunit PAN3 4BWPA 3.6 Inactive DFGin None out-none out-none AN2 Type1
Drosophila melanogaster PAN3 PAN3_DROME PAN2-PAN3 deadenylation complex subunit PAN3 4BWPB 3.6 Inactive DFGin None out-none out-none AN2 Type1
Equus caballus MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0A 2.746 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Equus caballus MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0B 2.746 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Equus caballus MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0C 2.746 Inactive DFGin BLBminus in-in out-out No_ligand No_ligand
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBA 3.05 Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 2VWBB 3.05 Inactive DFGin None in-in in-none ANP Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9A 2.67 Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3EN9B 2.67 Inactive DFGin None in-in in-none TBR Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHA 3.6 Inactive DFGin None in-in in-none TBR TBR TBR Allosteric Allosteric Allosteric
Methanocaldococcus jannaschii BUD32 KAE1B_METJA Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein 3ENHB 3.6 Inactive DFGin None in-in in-none TBR TBR TBR TBR Allosteric Allosteric Allosteric Allosteric
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVIA 2.2 Inactive DFGin ABAminus in-in in-in YFY Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVHA 2.65 Active DFGin BLAminus in-in in-in YFS Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVHB 2.65 Active DFGin BLAminus in-in in-in YFV Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7LVIB 2.2 Active DFGin BLAminus in-in in-in YFV Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ6A 2.132 Active DFGin BLAminus in-in in-in YFV Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ6B 2.132 Active DFGin BLAminus in-in in-in 5OI Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ7A 2.124 Active DFGin BLAminus in-in in-in 5P6 Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ7B 2.124 Active DFGin BLAminus in-in in-in 5P6 Type1
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8A 2.59 Active DFGin BLAminus in-in in-in 5QI PG6 Type1 Allosteric
Mus musculus AAK1 AAK1_MOUSE AP2-associated protein kinase 1 7RJ8B 2.59 Active DFGin BLAminus in-in in-in YFV PG6 Type1 Allosteric
Mus musculus EIF2AK3 E2AK3_MOUSE Eukaryotic translation initiation factor 2-alpha kinase 3 3QD2B 2.81 Inactive DFGin None in-in in-none No_ligand No_ligand
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3A 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL3B 2.9 Inactive DFGin BLBplus out-out out-in 31J ADP Allosteric Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4A 3.0 Inactive DFGin BLBplus out-out out-in 31K ADP Allosteric Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5A 3.4 Inactive DFGin BLBplus out-out out-in 31L ADP PEU Allosteric Type1 Allosteric
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4B 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4C 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL4D 3.0 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5B 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5C 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus ERN1 ERN1_MOUSE Serine/threonine-protein kinase/endoribonuclease IRE1 4PL5D 3.4 Inactive DFGin BLBplus out-out out-in ADP Type1
Mus musculus MLKL MLKL_MOUSE Mixed lineage kinase domain-like protein 4M68A 1.696 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
Mus musculus MLKL MLKL_MOUSE Mixed lineage kinase domain-like protein 4BTFA 2.604 Inactive DFGin BLAplus out-out out-out No_ligand No_ligand
Mus musculus MLKL MLKL_MOUSE Mixed lineage kinase domain-like protein 4M69B 2.497 Inactive None None out-out out-out No_ligand No_ligand
Mus musculus POMK SG196_MOUSE Protein O-mannose kinase 5GZ8A 2.5 Inactive DFGin ABAminus none-none in-out No_ligand No_ligand
Mus musculus POMK SG196_MOUSE Protein O-mannose kinase 5GZ9A 2.4 Inactive DFGin ABAminus none-none in-out ANP MAN Type1 Allosteric
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 4JL9A 3.1 Inactive DFGin BLAplus out-out out-out BX7 Type1
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 4JLCA 3.0 Inactive DFGin BLAplus out-out out-out SU6 Type1
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 6O8CA 3.17 Inactive DFGin BLBplus out-out none-none BX7 Type1
Mus musculus TBK1 TBK1_MOUSE Serine/threonine-protein kinase TBK1 6O8CB 3.17 Inactive DFGin BLBplus out-out none-out BX7 Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QB 2.88 Inactive DFGin BLAminus in-in in-out CJJ Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QC 2.88 Inactive DFGin BLAminus in-in in-out CJJ Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QD 2.88 Inactive DFGin BLAminus in-in in-out CJJ Type1
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 6B2QA 2.88 Inactive DFGin BLAminus in-in in-out CJJ 0BD Type1 Allosteric
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4OW8A 2.03 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FA 2.9 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FB 2.9 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FC 2.9 Inactive DFGin BLBminus out-none none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 1MRUA 3.0 Inactive DFGin ABAminus in-in in-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 1MRUB 3.0 Inactive DFGin ABAminus in-in in-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 6B2PA 3.01 None DFGin BLAminus in-in none-none CJJ Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 1O6YA 2.2 None DFGin BLAminus in-in in-none ACP Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMA 2.89 Inactive DFGin BLAminus in-in in-out MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMB 2.89 Inactive DFGin BLAminus in-in in-out MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMD 2.89 None DFGin BLAminus in-in none-out MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 5U94A 2.2 Active DFGin BLAminus in-in in-in G93 Type1.5_Back
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F61A 1.8 Inactive DFGin BLBminus in-out none-none ADP Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIA 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIB 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIC 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORID 2.0 Inactive DFGin BLBminus in-out out-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORKA 1.6 Inactive DFGin BLBminus in-out none-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORLA 2.9 Inactive DFGin BLBminus in-out none-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORPA 2.1 Inactive DFGin BLBminus out-out none-out AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORTA 1.9 Inactive DFGin BLBminus out-out out-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORMA 2.5 Inactive DFGin BLBminus in-out out-none AGS Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3OROA 1.9 Inactive DFGin BLBminus in-out out-out AGS NHE Type1 Allosteric
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 2FUMC 2.89 Inactive DFGin None in-out none-none MIX Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F69A 2.8 Inactive None None in-out out-none XDR Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F69B 2.8 Inactive None None in-out out-out XDR Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 6I2PA 2.37 Inactive None None in-out out-out ACP Type1
Mycobacterium tuberculosis PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 6I2PB 2.37 Inactive None None in-out none-none ACP Type1
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34A 2.8 Inactive DFGout None out-out none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNE PKNE_MYCTU Serine/threonine-protein kinase PknE 2H34B 2.8 Inactive DFGout None out-out none-out No_ligand No_ligand
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAA 2.75 Inactive DFGin None out-none none-none V17 Type1
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAB 2.75 Inactive DFGin None out-none none-out V17 Type1
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAC 2.75 Inactive DFGin None out-none none-none V17 Type1
Mycobacterium tuberculosis PKNF PKNF_MYCTU Serine/threonine-protein kinase PknF 7NAAD 2.75 Inactive DFGin None out-none none-none V17 Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 7Q52AAA 2.35 Inactive DFGin ABAminus out-out in-in FE 8ZC Allosteric Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 2PZIA 2.4 Inactive DFGin ABAminus out-out in-in AXX Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 2PZIB 2.4 Inactive DFGin ABAminus out-out in-in AXX Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 4Y0XA 1.74 Inactive DFGin BLAminus out-out in-in ADP Type1
Mycobacterium tuberculosis PKNG PKNG_MYCTU Serine/threonine-protein kinase PknG 4Y12A 1.9 None DFGin BLAminus out-none in-in AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWKA 3.3 Inactive DFGin None out-none out-none AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWKB 3.3 Inactive DFGin None out-none out-none AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4CZYB 3.4 Inactive DFGin None out-none out-none ANP Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4CZYD 3.4 Inactive DFGin None out-none out-none ANP Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWXA 2.85 Inactive DFGin None out-none out-none AGS Type1
Neurospora crassa PAN3 PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 4BWXB 2.85 Inactive DFGin None out-none out-none AGS Type1
Oryza sativa FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUPA 1.98 Inactive DFGin BLAminus in-in in-out ATP Type1
Oryza sativa FLS2 FLS2_ORYSJ LRR receptor-like serine/threonine-protein kinase FLS2 8JUVA 2.09 Inactive DFGin BLAminus in-in in-out ADP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 6EQIC 3.1 Inactive DFGin ABAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4KA 3.25 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4KB 3.25 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4LA 3.28 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4LB 3.28 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYFA 2.75 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYFB 2.75 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MA 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MB 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MC 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MD 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4ME 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MF 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MG 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MH 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MI 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MJ 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4MK 2.48 Inactive DFGin BLAminus in-out in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4ML 2.48 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4NA 2.35 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T4NB 2.35 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYHA 2.84 Active DFGin BLAminus in-in in-in ANP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYHB 2.84 Active DFGin BLAminus in-in in-in ANP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIA 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 8UYIB 3.13 Active DFGin BLAminus in-in in-in ADP Type1
Pediculus humanus PINK1 PINK1_PEDHC Serine/threonine-protein kinase Pink1, mitochondrial 7T3XA 3.53 Inactive DFGin None in-in in-in No_ligand No_ligand
Plasmodium falciparum PK7 O96214_PLAFA mitogen-activated protein kinase kinase 2PMLX 2.6 Inactive DFGin BLAminus out-out in-in ANP Type1
Plasmodium falciparum PK7 Q7YTF7_PLAF7 mitogen-activated protein kinase kinase 2PMNX 2.8 Inactive DFGin BLAminus in-out in-in K51 Type1
Plasmodium falciparum PK7 Q7YTF7_PLAF7 mitogen-activated protein kinase kinase 2PMOX 2.9 Active DFGin BLAminus in-in in-in HMD Type1
Rattus norvegicus MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZA 2.192 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand
Rattus norvegicus MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZB 2.192 Inactive DFGin BLBminus in-in none-out No_ligand No_ligand
Rattus norvegicus PRAG1 PRAG1_RAT Inactive tyrosine-protein kinase PRAG1 6EWXB 2.771 None DFGin BLAminus none-none in-out No_ligand No_ligand
Rattus norvegicus PRAG1 PRAG1_RAT Inactive tyrosine-protein kinase PRAG1 6EWXA 2.771 Inactive None None none-none in-none No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6CN9A 1.8 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 4Q2AA 3.5 Inactive DFGin BLAminus out-none out-out No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6CN9B 1.8 Inactive DFGin BLBminus out-none out-out No_ligand No_ligand
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 7UOSA 2.9 Inactive DFGin BLBminus out-none out-out WIB Type1
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6OL2A 2.1 Inactive DFGin BLBminus out-none out-out MU7 Type1.5_Back
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 5W7TA 2.01 Inactive DFGin BLBtrans out-none out-in ANP Type1
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 5W7TB 2.01 Inactive DFGin BLBtrans out-none out-in ANP Type1
Rattus norvegicus WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 5DRBA 1.65 Inactive DFGin BLBtrans out-none out-out 5FJ Type1.5_Front
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WWAA 2.953 None DFGin BLAminus in-none in-none No_ligand No_ligand
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW7A 1.669 Active DFGin BLAminus in-in in-none AMP Type1
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW9A 1.951 Active DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae BUD32 BUD32_YEAST EKC/KEOPS complex subunit BUD32 4WW5A 1.997 Active DFGin BLAminus in-in in-none ANP Type1.5_Front
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7PT68 3.2 Inactive DFGin ABAminus in-in in-in AGS Type1
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7PT6H 3.2 Inactive DFGin ABAminus in-in in-in AGS Type1
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7PT78 3.8 Inactive DFGin ABAminus in-out in-in ADP BEF Type1 Allosteric
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7V3VH 2.9 Active DFGin BLAminus in-in in-in AGS Type1
Saccharomyces cerevisiae CDC7 CDC7_YEAST Cell division control protein 7 7P5Z1 3.3 Inactive DFGin BLAplus in-out in-in No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4A 1.95 Inactive DFGin BLBminus out-out out-none No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4B 1.95 Inactive DFGin BLBminus out-out none-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCA 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCB 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCC 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCD 3.0 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEA 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEB 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEC 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXED 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEE 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEF 2.6 Inactive DFGin BLBminus out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5A 2.0 Inactive DFGin BLBminus out-out out-none ANP Type1
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5B 2.0 Inactive DFGin BLBminus out-out none-out ANP Type1
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDA 2.75 Inactive DFGin BLBminus out-out out-out ATP Type1
Saccharomyces cerevisiae GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDB 2.75 Inactive DFGin BLBminus out-out none-out ATP Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2A 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ2B 3.33 Inactive DFGin ABAminus in-in in-none IZA Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMA 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMB 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMC 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMD 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDME 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMF 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDMG 6.6 Inactive DFGin BLAminus in-in in-out No_ligand No_ligand
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVA 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVB 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVC 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVD 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVE 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVF 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVG 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVH 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVI 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVJ 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVK 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVL 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVM 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3FBVN 3.2 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJA 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJB 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJC 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJD 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJE 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJF 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJG 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJH 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJI 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJJ 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJK 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJL 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJM 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3SDJN 3.65 Inactive DFGin BLAminus in-in in-out APJ Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOA 2.4 None DFGin BLAminus out-in in-none ADP Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 2RIOB 2.4 None DFGin BLAminus in-in in-none ADP Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ1A 3.33 None DFGin BLAminus in-in in-none DKI Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ1B 3.33 None DFGin BLAminus in-in in-none DKI Type1
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0A 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae IRE1 IRE1_YEAST Serine/threonine-protein kinase/endoribonuclease IRE1 3LJ0B 3.2 None DFGin BLAminus in-in in-none ADP QUE Type1 Allosteric
Saccharomyces cerevisiae VPS15 VPS15_YEAST Serine/threonine-protein kinase VPS15 5KC2B 28.0 Inactive None None out-none none-none No_ligand No_ligand
Saccharomyces cerevisiae VPS15 VPS15_YEAST Serine/threonine-protein kinase VPS15 5DFZB 4.4 Inactive None None out-none none-none No_ligand No_ligand
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1RA 1.6 Inactive DFGin ABAminus in-out out-out No_ligand No_ligand
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5HNVA 1.41 Inactive DFGin ABAminus in-out out-out ATP Type1
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1QA 1.602 Inactive DFGin ABAminus in-out out-out ATP Type1
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1SA 1.45 Inactive DFGin ABAminus in-out out-out ACP Type1
Serratia sp. PPKA A0A1S4NYE5_SERSF PpkA N terminal 5X1TA 1.55 Inactive DFGin ABAminus in-out out-out ADP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMA 3.0 None DFGin BLAminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMD 3.0 None DFGin BLAminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQME 3.0 None DFGin BLAminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMB 3.0 Inactive DFGin BLBminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMC 3.0 Inactive DFGin BLBminus out-out out-none ANP Type1
Staphylococcus aureus PKNB A0A0H3JME9_STAAN Protein kinase 4EQMF 3.0 Inactive DFGin None out-out out-none ANP Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OA 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OB 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OC 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1OD 3.27 Inactive DFGin ABAminus in-in in-none 25L Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PA 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PB 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PC 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 4O1PD 2.5 Inactive DFGin ABAminus in-in in-none ANP 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M11a 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M11b 2.46 Active DFGin BLAminus in-in in-none 25A B49 Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M12b 2.4 Active DFGin BLAminus in-in in-none 25L J60 Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DSYa 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DSYb 2.651 Active DFGin BLAminus in-in in-none 25A HFX Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DTSa 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7DTSb 2.63 Active DFGin BLAminus in-in in-none 25A 27K Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7ELWa 3.55 Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 7ELWb 3.55 Active DFGin BLAminus in-in in-none 25L MYC Allosteric Type1
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M12a 2.4 Active DFGin BLAminus in-in in-none J60 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M13a 2.56 Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric
Sus scrofa RNASEL A5H025_PIG Ribonuclease L 6M13b 2.56 Active DFGin BLAminus in-in in-none BWC 25L Type1 Allosteric
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5YJ9D 2.53 Inactive DFGin ABAminus in-in in-in ANP Type1
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATA 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATB 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATC 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATD 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATE 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 5OATF 2.78 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 7MP8A 3.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand
Tribolium castaneum PINK1 PINK1_TRICA Serine/threonine-protein kinase Pink1, mitochondrial 7MP9A 2.8 Inactive DFGin None in-in in-in AN2 Type1
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3RZFA 4.0 Inactive DFGin BLAminus in-in in-out XNM Type1
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8A 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8B 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8C 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8D 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8E 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8F 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8G 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Xenopus laevis IKBKBL Q6INT1_XENLA IkappaB kinase 3QA8H 3.6 Inactive DFGout None in-in out-out No_ligand No_ligand
Zea mays DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6CPYA 1.7 Inactive DFGout BBAminus in-none out-none No_ligand No_ligand
Zea mays DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6CPYB 1.7 Inactive DFGout BBAminus out-none out-none No_ligand No_ligand
Zea mays DRIK1 C0P4K9_MAIZE Protein kinase superfamily protein 6EASA 2.0 Inactive DFGout BBAminus out-none out-none J3A Type1
Zea mays SIRK1 K7VIQ3_MAIZE Putative leucine-rich repeat protein kinase family protein 5UV4A 2.3 Inactive DFGin BLBplus out-out out-out ANP Type1