Protein kinases in complex with HUH

Total number of genes: 2
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 6QAGA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAGA 2.07 Inactive DFGin BLAminus out-out in-in HUH HUH Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75B 1.3 Inactive DFGin BLAminus in-out in-in LU8 HUH HUH Type1 Allosteric Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HUH HUH Type1 Allosteric Allosteric Allosteric Allosteric

Protein kinases in complex with HUH

Total number of genes: 2
Total number of chains: 3
Spatial Dihedral Chains Representative
DFGin BLAminus 3 6QAGA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6QAGA 2.07 Inactive DFGin BLAminus out-out in-in HUH HUH Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75B 1.3 Inactive DFGin BLAminus in-out in-in LU8 HUH HUH Type1 Allosteric Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S75A 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 HUH HUH Type1 Allosteric Allosteric Allosteric Allosteric

Protein kinases in complex with HUH

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type