Protein kinases with BLBminus conformation in complex with All ligands

Total number of genes: 40
Total number of chains: 270
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
BLBminus 1 9 0 136 1 0 29 23 58 13 5NKGA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Group Gene UniprotID Protein name PDB Resolution Activity Label Chelix-SaltBridge ActloopNT-ActLoopCT Ligand Type
AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S26C 2.744 Inactive in-in none-none 86K Type1
CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3ZXTA 2.65 Inactive in-in in-none ACP Type1
CAMK MARK3 MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 7P1LA 1.95 Inactive out-out out-none V5E Type1
CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5IHCA 2.14 Inactive out-out none-none 6BB Type1
CAMK MKNK2 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 8XFMA 2.6 Inactive in-in out-out A1LU6 Type1
CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 6KZIA 2.8 Inactive in-in in-in RTX Type1
CAMK PLK2 PLK2_HUMAN Serine/threonine-protein kinase PLK2 4I6HA 1.91 Inactive in-in in-out 1C8 Type1
CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 7MYJA 2.95 Inactive out-in in-in 4O7 ZQV Type1 Allosteric
CAMK SNRK SNRK_HUMAN SNF-related serine/threonine-protein kinase 5YKSA 2.9 Inactive out-out none-none No_ligand No_ligand
CAMK SNRK SNRK_HUMAN SNF-related serine/threonine-protein kinase 5YKSB 2.9 Inactive out-out out-out No_ligand No_ligand
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXFA 1.8 Inactive out-out out-out 2AN 2AN Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXZA 1.7 Inactive out-out out-out 2AN 2AN JWS Allosteric Type3 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6YL6A 1.7 Inactive out-out out-out No_ligand No_ligand
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UXIA 2.07 Inactive out-out out-out No_ligand No_ligand
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5OO3A 1.73 Inactive out-out out-out 9ZB Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6YL1A 1.66 Inactive out-out out-out OWN Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6YLKA 1.65 Inactive out-out out-out OY2 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1DM2A 2.1 Inactive out-out none-out HMD Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1G5SA 2.61 Inactive out-out none-out I17 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1P2AA 2.5 Inactive out-out none-out 5BN Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1PF8A 2.51 Inactive out-out out-out SU9 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2B52A 1.88 Inactive out-out none-out D42 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2B55A 1.85 Inactive out-out none-out D31 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2BHEA 1.9 Inactive out-out none-out BRY Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2BHHA 2.6 Inactive out-out none-out RYU Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2BTSA 1.99 Inactive out-out none-out U32 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2C5YA 2.25 Inactive out-out out-out MTW Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2FVDA 1.85 Inactive out-out none-out LIA Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2J9MA 2.5 Inactive out-out none-out PY8 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTNA 2.2 Inactive out-out none-out LZ7 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTQA 1.9 Inactive out-out none-out LZA Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTTA 1.68 Inactive out-out none-out LZD Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VU3A 1.85 Inactive out-out none-out LZE Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3TI1A 1.99 Inactive out-out out-out B49 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3TIZA 2.02 Inactive out-out out-out 3TI Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3UNJA 1.9 Inactive out-out out-out 0BX Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3UNKA 2.1 Inactive out-out out-out 0BY Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5ANGA 1.9 Inactive out-out none-out WY3 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7M2FA 1.632 Inactive out-out none-out YOS Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8ERDA 1.33 Inactive out-out out-out WQ6 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6INLA 1.75 Inactive out-out none-out AJR Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2R3NA 1.63 Inactive out-out none-out SCZ Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VV9A 1.9 Inactive out-out none-out IM9 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2W17A 2.15 Inactive out-out none-out I19 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3SW7A 1.8 Inactive out-out none-out 19K Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4BZDA 1.83 Inactive out-none none-out D6I Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4FKOA 1.55 Inactive out-out out-out 20K Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EZVA 1.99 Inactive out-out none-out EZV Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RA5A 1.67 Inactive out-out none-out 3I3 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXYA 1.8 Inactive out-out out-out JWS Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY0A 1.75 Inactive out-out out-out SU9 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQGA 1.9 Inactive out-out out-out X06 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQHA 1.87 Inactive out-out out-out X0A Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQKA 1.86 Inactive out-out out-out X02 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QRTA 1.75 Inactive out-out out-out X14 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QRUA 1.95 Inactive out-out out-out X19 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTQA 1.8 Inactive out-out out-out X35 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTRA 1.85 Inactive out-out out-out X36 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTUA 1.82 Inactive out-out out-out X44 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTXA 1.95 Inactive out-out out-out X43 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTZA 2.0 Inactive out-out out-out X42 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QWKA 1.85 Inactive out-out out-out X62 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QXPA 1.75 Inactive out-out out-out X64 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3R8MA 1.8 Inactive out-out out-out Z19 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3R8ZA 1.85 Inactive out-out out-out Z63 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RAKA 1.75 Inactive out-out none-out 03Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RALA 1.75 Inactive out-out none-out 04Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RJCA 1.85 Inactive out-out out-out 06Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RK9A 1.85 Inactive out-out out-out 09Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RMFA 1.75 Inactive out-out none-out 20Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RNIA 1.95 Inactive out-out out-out 21Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RPVA 1.8 Inactive out-out out-out 26Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RPYA 1.9 Inactive out-out none-out 27Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3S1HA 1.75 Inactive out-out none-out 56Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3SQQA 1.85 Inactive out-out out-out 99Z Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4ERWA 2.0 Inactive out-out out-out STU Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ3A 2.0 Inactive out-out out-out 0S0 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4GCJA 1.42 Inactive out-out out-out X64 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6GUHA 1.5 Inactive out-out none-out FB8 Type1
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4D1ZA 1.851 Inactive out-none none-none WG8 WG8 Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP5A 2.16 Inactive out-none none-none 1Y6 1Y6 Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP6A 1.85 Inactive out-out none-out MFZ MFZ Type1 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXQA 1.9 Inactive out-out out-out 2AN 2AN 2AN Type1 Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY1A 2.05 Inactive out-out out-out SU9 2AN 2AN Type1 Allosteric Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWEA 1.59 Inactive none-none none-none 7TH 7TH Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7SA0A 1.59 Inactive out-out out-out 8KQ 8KQ Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FOWA 1.6 Inactive out-out out-out 1QK 7TW Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP0A 1.6 Inactive out-out out-out RRC 7TW Type1 Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ7A 2.49 Inactive out-out out-out STU 2AN 2AN Type1 Type3 Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RXOA 1.38 Inactive out-none out-out 80E Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S4TA 1.91 Inactive out-out out-out 88O Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S7AA 1.7 Inactive out-none out-out 8FI Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S84A 2.0 Inactive out-out out-out 8IL Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S85A 1.98 Inactive out-out out-out 8IQ Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S9XA 1.69 Inactive out-out out-out 8KF Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWFA 1.5 Inactive out-out out-out 7TW Type3
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UG1A 1.84 Inactive out-out out-out N5R N5R Type3 Allosteric
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4G6LA 2.7 Inactive in-in out-none No_ligand No_ligand
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5FGKA 2.36 Inactive in-in none-out 5XG Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5HBEA 2.38 Inactive in-in out-out 5Y6 Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5HNBA 2.35 Inactive in-in out-none 62M Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5I5ZA 2.6 Inactive in-in out-none 68U Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5IDPA 2.65 Inactive in-in out-none 6A6 Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F7SA 2.2 Inactive in-in out-none 0SW Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5BNJA 2.64 Inactive in-in out-none 4TV Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6QTGA 2.7 Inactive in-in none-out JH8 Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4CRLA 2.4 Inactive in-in out-out C1I Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5CEIA 2.24 Inactive in-in out-none 50R Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6R3SA 2.19 Inactive in-in out-none JRE Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6Y0AA 2.19 Inactive in-in out-none JRE Type1
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6T41A 2.45 Inactive in-in out-none MFE Type1
CMGC CDKL2 CDKL2_HUMAN Cyclin-dependent kinase-like 2 4AAAA 1.53 Inactive out-none none-out DKI Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N68A 1.85 Inactive in-in none-none 8OK Allosteric
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2Y8OA 1.95 Inactive in-in out-none No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1R3CA 2.0 Inactive in-in out-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2LGCA 999.0 Inactive out-out out-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ETAA 2.8 Inactive out-out none-none No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ETAB 2.8 Inactive out-out none-none No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1R39A 2.3 Inactive in-out none-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2OKRA 2.0 Inactive in-in out-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2OKRD 2.0 Inactive in-in out-none No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ONLA 4.0 Inactive in-in out-none No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ONLB 4.0 Inactive in-in out-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ETFA 2.4 Inactive out-none none-out No_ligand No_ligand
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BMKA 2.4 Inactive in-out out-out SB5 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MW1A 2.8 Inactive in-in none-out MIH Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1DI9A 2.6 Inactive in-in out-out MSQ Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1W7HA 2.214 Inactive in-in out-out 3IP Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1W84A 2.2 Inactive in-in out-out L12 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ZB0A 2.1 Inactive in-in out-out GK3 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1M7QA 2.4 Inactive in-in out-out DQO Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1OUKA 2.5 Inactive in-in out-out 084 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1OUYA 2.5 Inactive in-in out-out 094 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1YQJA 2.0 Inactive in-out out-out 6NP Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZYAA 1.9 Inactive out-in none-out 2A8 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1OZ1A 2.1 Inactive in-in out-out FPH Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3FLQA 1.9 Inactive in-in out-out 891 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3FMJA 2.0 Inactive in-in out-out FMJ Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3FSFA 2.1 Inactive in-in none-out FSS Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1A9UA 2.5 Inactive in-in out-out SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BL6A 2.5 Inactive in-in out-out SB6 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BL7A 2.5 Inactive in-in out-out SB4 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MPAA 2.1 Inactive in-in none-none SB2 Type1
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ZB1A 2.5 Inactive in-in none-out GK4 Type1.5_Back
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5XYXA 2.61 Inactive in-in none-out FTZ Type1.5_Back
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5XYYA 1.7 Inactive in-in out-out P0F Type1.5_Back
NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M53A 1.9 Inactive out-out none-out 7GJ Type1
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4MWIA 1.7 Inactive in-in out-out PXN Allosteric
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6BWKA 2.79 Inactive in-none none-out No_ligand No_ligand
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JW7A 2.63 Inactive in-in none-out No_ligand No_ligand
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 8SLZA 2.3 Inactive in-in out-out No_ligand No_ligand
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4M67A 1.9 Inactive in-in out-out No_ligand No_ligand
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK6A 2.41 Inactive in-in out-out No_ligand No_ligand
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK5A 2.5 Inactive in-in out-out No_ligand No_ligand
OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KO1A 2.16 Inactive in-in out-out 6UY Type1
OTHER PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SORA 3.96 Inactive out-out out-out ADP Type1
OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VA 1.723 Inactive out-none out-out No_ligand No_ligand
OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VB 1.723 Inactive out-none out-out No_ligand No_ligand
OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2CA 2.4 Inactive out-none out-in No_ligand No_ligand
OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2BB 2.038 Inactive out-none out-none KS1 Type1
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8CHFE 4.25 Inactive out-out out-out No_ligand No_ligand
STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8CHFF 4.25 Inactive out-out out-out No_ligand No_ligand
STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 7QGPA 1.9 Inactive in-out out-out DJ8 Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3ZHPC 2.9 Inactive out-out out-out No_ligand No_ligand
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3ZHPD 2.9 Inactive out-none out-out No_ligand No_ligand
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8BZIA 1.72 Inactive out-out none-none SJL Type1.5_Back
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8BZJA 2.52 Inactive out-out none-none SJX Type1.5_Back
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B30A 2.1 Inactive out-out none-none 59T Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B31A 1.8 Inactive out-out none-none SQ8 Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B32A 1.75 Inactive out-out none-none SQQ Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B33A 1.9 Inactive out-out none-none SQE Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B34A 2.1 Inactive out-out none-none SQK Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B35A 2.4 Inactive out-out none-none SQB Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B35B 2.4 Inactive out-out none-none SQB Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8BZJB 2.52 Inactive out-out none-none SJX Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLRA 1.85 Inactive out-out none-none VYN Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLRB 1.85 Inactive out-out none-none VYN Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLSA 1.61 Inactive out-out none-none VYH Type1.5_Front
STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLTA 1.47 Inactive out-out none-none VZ2 Type1.5_Front
STE STK26 STK26_HUMAN Serine/threonine-protein kinase 26 7B36C 2.107 Inactive out-out none-out 59T Type1.5_Back
STE STK26 STK26_HUMAN Serine/threonine-protein kinase 26 7B36A 2.107 Inactive out-out none-out 59T Type1.5_Front
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4A 2.42 Inactive out-out out-out No_ligand No_ligand
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4B 2.42 Inactive out-out none-out No_ligand No_ligand
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4C 2.42 Inactive in-in out-out No_ligand No_ligand
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4E 2.42 Inactive out-out out-out No_ligand No_ligand
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDA 3.05 Inactive out-out out-out ANP Type1
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDB 3.05 Inactive out-out out-out ANP Type1
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDC 3.05 Inactive out-out out-out ANP Type1
STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDD 3.05 Inactive out-out out-out ANP Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 3SKCA 3.2 Inactive out-out none-out BR2 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4E26B 2.55 Inactive in-in in-out 734 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEA 3.0 Inactive out-out out-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEB 3.0 Inactive out-out out-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEC 3.0 Inactive out-out none-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIED 3.0 Inactive out-out none-out P06 Type1
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 7P3VA 2.37 Inactive out-out none-out 5I4 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 7P3VB 2.37 Inactive out-out out-out 5I4 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4CQEB 2.3 Inactive in-out none-out CQE Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2A 2.5 Inactive out-out none-out P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2B 2.5 Inactive in-out none-out P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CSWB 2.66 Inactive out-out none-none P06 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6V2UB 3.78 Inactive out-out none-none P06 Type1.5_Back
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 2NRYA 2.15 Inactive in-in in-in STU Type1
TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 2NRYB 2.15 Inactive in-out in-in STU Type1
TKL MAP3K12 M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 5CENA 1.7 Inactive out-out out-out No_ligand No_ligand
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 2EVAA 2.0 Inactive in-in none-out ADN Type1
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 4GS6A 2.2 Inactive in-in none-out 1FM Type1
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 4L3PA 2.68 Inactive in-in none-in 1UH Type1
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5JGBA 2.8 Inactive in-none none-out 6JV Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 6S1FA 3.11 Inactive in-in out-out KRE Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 6S1FC 3.11 Inactive in-in out-out KRE Type1
TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR8B 2.79 Inactive out-out none-out XYW Type1.5_Back
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXIC 3.0 Inactive out-out none-in 8BS Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RJ6A 2.7 Inactive in-in in-in 3R0 Type1
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5EM6A 2.78 Inactive in-in in-in 5Q3 Type1.5_Back
TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2DA 1.11 Inactive out-out none-in KXY Type3
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9WA 1.359 Inactive in-in none-in ANP Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9XA 1.427 Inactive in-in out-in DB8 Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9YA 1.228 Inactive in-in out-none 1N1 Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9ZA 1.698 Inactive in-in out-in 627 Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA0B 1.948 Inactive in-in out-in A5B Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA0C 1.948 Inactive in-in none-none A5B Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA3A 1.788 Inactive in-in out-in P17 Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NJZA 1.768 Inactive in-in none-in 8ZH Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK1A 1.548 Inactive in-in out-in 90N Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK2A 1.649 Inactive in-in out-in 8ZZ Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK4A 1.45 Inactive in-in out-in 90E Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK5A 1.329 Inactive in-in out-in 90K Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK6A 1.267 Inactive in-out out-in 90W Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK7A 1.889 Inactive in-in out-in 8ZZ Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK9A 1.588 Inactive in-out out-in 912 Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKBA 1.5 Inactive in-in out-in 8ZT Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKCA 1.448 Inactive in-in out-in 90T Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKDA 1.408 Inactive in-in out-in 91K Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKEA 1.39 Inactive in-in out-in 90B Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKFA 1.099 Inactive in-out out-in 8ZN Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKGA 1.1 Inactive in-out out-in 8ZK Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKHA 1.29 Inactive in-in out-in 8ZQ Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKIA 1.675 Inactive in-in none-none 8ZW Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 8BK0A 1.7 Inactive in-in out-in QJI Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 7KJCA 2.3 Inactive in-in out-in ACP Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 7KJCB 2.3 Inactive in-in none-none ACP Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 7KJAA 1.75 Inactive in-in none-none ACP Type1
TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA2A 1.619 Inactive in-out out-in L66 Type1.5_Back
TYR EPHA7 EPHA7_HUMAN Ephrin type-A receptor 7 7EEFA 2.6 Inactive in-in none-in No_ligand No_ligand
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 6FNKA 1.049 Inactive in-in out-in DXK Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 6FNMA 1.157 Inactive in-in out-in 1N1 Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 4AW5A 2.33 Inactive in-in none-in 30K Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VWXA 1.65 Inactive in-in out-in 7X4 Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VWYA 1.65 Inactive in-in out-in 7X5 Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VWZA 1.65 Inactive in-in out-in 7X6 Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VX0A 2.1 Inactive in-in out-in 7X7 Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VX1A 1.65 Inactive in-in out-in 7X8 Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2X9FA 1.75 Inactive in-in out-in X9F Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 4BB4A 1.65 Inactive in-in out-in 32W Type1
TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2XVDA 1.7 Inactive in-in out-in AS6 Type1.5_Back
TYR ERBB2 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 7PCDA 1.77 Inactive out-out out-in 70I Type1.5_Back
TYR ERBB2 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 7JXHA 3.27 Inactive out-out out-out VOY Type1.5_Back
TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 3KXXA 3.2 Inactive in-in in-in No_ligand No_ligand
TYR FGFR2 FGFR2_HUMAN Fibroblast growth factor receptor 2 6V6QC 2.46 Inactive in-in in-in ACP Type1
TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3QQUA 2.9 Inactive in-out out-in 01P Type1
TYR LCK LCK_HUMAN Tyrosine-protein kinase Lck 3B2WA 2.3 Inactive in-in out-in 9NH Type1
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AVYA 2.31 Inactive out-out none-none S4E Type1
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW2A 2.1 Inactive out-out none-none S4W Type1.5_Front
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7OLSA 1.89 Inactive out-out none-none VJZ Type1.5_Front
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7OLVA 2.13 Inactive out-out none-none VK2 Type1.5_Front
TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7OLXA 1.98 Inactive out-out none-none VK5 Type1.5_Front
TYR MET MET_HUMAN Hepatocyte growth factor receptor 3Q6UA 1.6 Inactive in-out none-in AME Allosteric
TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 2IJMB 2.187 Inactive in-out none-out ADP Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 1FMKA 1.5 Inactive out-out out-out No_ligand No_ligand

Protein kinases with BLBminus conformation in complex with All ligands

Total number of genes: 54
Total number of chains: 411
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
BLBminus 1 24 0 209 1 0 29 26 65 56 5NKGA
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein name PDB Resolution Activity Label Chelix-SaltBridge ActloopNT-ActLoopCT Ligand Type
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTA 2.3 Inactive out-out out-out CPS Type1
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTB 2.3 Inactive out-out out-out CPS Type1
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUA 1.9 Inactive out-out out-out CPS Type1
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTC 2.3 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUB 1.9 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUC 1.9 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUD 1.9 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTD 2.3 Inactive out-out out-out CPS CPS CPS Type1 Allosteric Allosteric
Arabidopsis thaliana CAMK CIPK24 CIPKO_ARATH CBL-interacting serine/threonine-protein kinase 24 4D28C 3.3 Inactive out-out out-out No_ligand No_ligand
Arabidopsis thaliana CMGC MPK6 MPK6_ARATH Mitogen-activated protein kinase 6 5CI6A 3.0 Inactive in-out out-out No_ligand No_ligand
Arabidopsis thaliana OTHER BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68A 2.0 Inactive out-out out-in PDO Allosteric
Arabidopsis thaliana OTHER BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68B 2.0 Inactive out-out out-out No_ligand No_ligand
Arabidopsis thaliana TKL SOBIR1 SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 7CTVA 2.886 Inactive out-none out-out ANP Type1
Arabidopsis thaliana TKL SOBIR1 SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 7CTVB 2.886 Inactive out-none out-out ANP Type1
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F0GA 2.0 Inactive in-in none-none No_ligand No_ligand
Equus caballus OTHER MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0A 2.746 Inactive in-in out-out No_ligand No_ligand
Equus caballus OTHER MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0B 2.746 Inactive in-in out-out No_ligand No_ligand
Equus caballus OTHER MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0C 2.746 Inactive in-in out-out No_ligand No_ligand
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3U51A 2.241 Inactive out-out none-out No_ligand No_ligand
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3U51B 2.241 Inactive out-out none-none No_ligand No_ligand
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3SVVA 2.204 Inactive in-in out-none VSP Type1.5_Back
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3SVVB 2.204 Inactive in-in none-none VSP Type1.5_Back
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 4DGGA 2.65 Inactive out-none none-out I76 Type1.5_Front
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5J5SA 2.153 Inactive out-out none-none 6G3 Type1.5_Front
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5J5SB 2.153 Inactive out-out none-none 6G3 Type1.5_Front
Giardia intestinalis CMGC CDK A8BZ95_GIAIC Kinase, CMGC CDK 3GBZA 1.85 Inactive out-none out-none No_ligand No_ligand
Giardia intestinalis CMGC CDK A8BZ95_GIAIC Kinase, CMGC CDK 3GC0A 2.0 Inactive out-none out-out AMP Type1
Homo sapiens AGC ROCK1 ROCK1_HUMAN Rho-associated protein kinase 1 7S26C 2.744 Inactive in-in none-none 86K Type1
Homo sapiens CAMK DAPK1 DAPK1_HUMAN Death-associated protein kinase 1 3ZXTA 2.65 Inactive in-in in-none ACP Type1
Homo sapiens CAMK MARK3 MARK3_HUMAN MAP/microtubule affinity-regulating kinase 3 7P1LA 1.95 Inactive out-out out-none V5E Type1
Homo sapiens CAMK MELK MELK_HUMAN Maternal embryonic leucine zipper kinase 5IHCA 2.14 Inactive out-out none-none 6BB Type1
Homo sapiens CAMK MKNK2 MKNK2_HUMAN MAP kinase-interacting serine/threonine-protein kinase 2 8XFMA 2.6 Inactive in-in out-out A1LU6 Type1
Homo sapiens CAMK PIM1 PIM1_HUMAN Serine/threonine-protein kinase pim-1 6KZIA 2.8 Inactive in-in in-in RTX Type1
Homo sapiens CAMK PLK2 PLK2_HUMAN Serine/threonine-protein kinase PLK2 4I6HA 1.91 Inactive in-in in-out 1C8 Type1
Homo sapiens CAMK PRKAA2 AAPK2_HUMAN 5'-AMP-activated protein kinase catalytic subunit alpha-2 7MYJA 2.95 Inactive out-in in-in 4O7 ZQV Type1 Allosteric
Homo sapiens CAMK SNRK SNRK_HUMAN SNF-related serine/threonine-protein kinase 5YKSA 2.9 Inactive out-out none-none No_ligand No_ligand
Homo sapiens CAMK SNRK SNRK_HUMAN SNF-related serine/threonine-protein kinase 5YKSB 2.9 Inactive out-out out-out No_ligand No_ligand
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXFA 1.8 Inactive out-out out-out 2AN 2AN Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXZA 1.7 Inactive out-out out-out 2AN 2AN JWS Allosteric Type3 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6YL6A 1.7 Inactive out-out out-out No_ligand No_ligand
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UXIA 2.07 Inactive out-out out-out No_ligand No_ligand
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5OO3A 1.73 Inactive out-out out-out 9ZB Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6YL1A 1.66 Inactive out-out out-out OWN Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6YLKA 1.65 Inactive out-out out-out OY2 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1DM2A 2.1 Inactive out-out none-out HMD Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1G5SA 2.61 Inactive out-out none-out I17 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1P2AA 2.5 Inactive out-out none-out 5BN Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 1PF8A 2.51 Inactive out-out out-out SU9 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2B52A 1.88 Inactive out-out none-out D42 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2B55A 1.85 Inactive out-out none-out D31 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2BHEA 1.9 Inactive out-out none-out BRY Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2BHHA 2.6 Inactive out-out none-out RYU Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2BTSA 1.99 Inactive out-out none-out U32 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2C5YA 2.25 Inactive out-out out-out MTW Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2FVDA 1.85 Inactive out-out none-out LIA Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2J9MA 2.5 Inactive out-out none-out PY8 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTNA 2.2 Inactive out-out none-out LZ7 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTQA 1.9 Inactive out-out none-out LZA Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VTTA 1.68 Inactive out-out none-out LZD Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VU3A 1.85 Inactive out-out none-out LZE Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3TI1A 1.99 Inactive out-out out-out B49 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3TIZA 2.02 Inactive out-out out-out 3TI Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3UNJA 1.9 Inactive out-out out-out 0BX Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3UNKA 2.1 Inactive out-out out-out 0BY Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5ANGA 1.9 Inactive out-out none-out WY3 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7M2FA 1.632 Inactive out-out none-out YOS Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8ERDA 1.33 Inactive out-out out-out WQ6 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6INLA 1.75 Inactive out-out none-out AJR Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2R3NA 1.63 Inactive out-out none-out SCZ Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2VV9A 1.9 Inactive out-out none-out IM9 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 2W17A 2.15 Inactive out-out none-out I19 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3SW7A 1.8 Inactive out-out none-out 19K Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4BZDA 1.83 Inactive out-none none-out D6I Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4FKOA 1.55 Inactive out-out out-out 20K Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3EZVA 1.99 Inactive out-out none-out EZV Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RA5A 1.67 Inactive out-out none-out 3I3 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXYA 1.8 Inactive out-out out-out JWS Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY0A 1.75 Inactive out-out out-out SU9 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQGA 1.9 Inactive out-out out-out X06 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQHA 1.87 Inactive out-out out-out X0A Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QQKA 1.86 Inactive out-out out-out X02 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QRTA 1.75 Inactive out-out out-out X14 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QRUA 1.95 Inactive out-out out-out X19 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTQA 1.8 Inactive out-out out-out X35 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTRA 1.85 Inactive out-out out-out X36 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTUA 1.82 Inactive out-out out-out X44 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTXA 1.95 Inactive out-out out-out X43 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QTZA 2.0 Inactive out-out out-out X42 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QWKA 1.85 Inactive out-out out-out X62 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3QXPA 1.75 Inactive out-out out-out X64 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3R8MA 1.8 Inactive out-out out-out Z19 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3R8ZA 1.85 Inactive out-out out-out Z63 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RAKA 1.75 Inactive out-out none-out 03Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RALA 1.75 Inactive out-out none-out 04Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RJCA 1.85 Inactive out-out out-out 06Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RK9A 1.85 Inactive out-out out-out 09Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RMFA 1.75 Inactive out-out none-out 20Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RNIA 1.95 Inactive out-out out-out 21Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RPVA 1.8 Inactive out-out out-out 26Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3RPYA 1.9 Inactive out-out none-out 27Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3S1HA 1.75 Inactive out-out none-out 56Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3SQQA 1.85 Inactive out-out out-out 99Z Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4ERWA 2.0 Inactive out-out out-out STU Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ3A 2.0 Inactive out-out out-out 0S0 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4GCJA 1.42 Inactive out-out out-out X64 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6GUHA 1.5 Inactive out-out none-out FB8 Type1
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4D1ZA 1.851 Inactive out-none none-none WG8 WG8 Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP5A 2.16 Inactive out-none none-none 1Y6 1Y6 Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 5FP6A 1.85 Inactive out-out none-out MFZ MFZ Type1 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PXQA 1.9 Inactive out-out out-out 2AN 2AN 2AN Type1 Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 3PY1A 2.05 Inactive out-out out-out SU9 2AN 2AN Type1 Allosteric Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWEA 1.59 Inactive none-none none-none 7TH 7TH Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7SA0A 1.59 Inactive out-out out-out 8KQ 8KQ Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FOWA 1.6 Inactive out-out out-out 1QK 7TW Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 8FP0A 1.6 Inactive out-out out-out RRC 7TW Type1 Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 4EZ7A 2.49 Inactive out-out out-out STU 2AN 2AN Type1 Type3 Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RXOA 1.38 Inactive out-none out-out 80E Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S4TA 1.91 Inactive out-out out-out 88O Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S7AA 1.7 Inactive out-none out-out 8FI Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S84A 2.0 Inactive out-out out-out 8IL Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S85A 1.98 Inactive out-out out-out 8IQ Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7S9XA 1.69 Inactive out-out out-out 8KF Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7RWFA 1.5 Inactive out-out out-out 7TW Type3
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 7UG1A 1.84 Inactive out-out out-out N5R N5R Type3 Allosteric
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4G6LA 2.7 Inactive in-in out-none No_ligand No_ligand
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5FGKA 2.36 Inactive in-in none-out 5XG Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5HBEA 2.38 Inactive in-in out-out 5Y6 Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5HNBA 2.35 Inactive in-in out-none 62M Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5I5ZA 2.6 Inactive in-in out-none 68U Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5IDPA 2.65 Inactive in-in out-none 6A6 Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4F7SA 2.2 Inactive in-in out-none 0SW Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5BNJA 2.64 Inactive in-in out-none 4TV Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6QTGA 2.7 Inactive in-in none-out JH8 Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 4CRLA 2.4 Inactive in-in out-out C1I Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 5CEIA 2.24 Inactive in-in out-none 50R Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6R3SA 2.19 Inactive in-in out-none JRE Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6Y0AA 2.19 Inactive in-in out-none JRE Type1
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 6T41A 2.45 Inactive in-in out-none MFE Type1
Homo sapiens CMGC CDKL2 CDKL2_HUMAN Cyclin-dependent kinase-like 2 4AAAA 1.53 Inactive out-none none-out DKI Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5N68A 1.85 Inactive in-in none-none 8OK Allosteric
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2Y8OA 1.95 Inactive in-in out-none No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1R3CA 2.0 Inactive in-in out-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2LGCA 999.0 Inactive out-out out-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ETAA 2.8 Inactive out-out none-none No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ETAB 2.8 Inactive out-out none-none No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1R39A 2.3 Inactive in-out none-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2OKRA 2.0 Inactive in-in out-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2OKRD 2.0 Inactive in-in out-none No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ONLA 4.0 Inactive in-in out-none No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ONLB 4.0 Inactive in-in out-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5ETFA 2.4 Inactive out-none none-out No_ligand No_ligand
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BMKA 2.4 Inactive in-out out-out SB5 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MW1A 2.8 Inactive in-in none-out MIH Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1DI9A 2.6 Inactive in-in out-out MSQ Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1W7HA 2.214 Inactive in-in out-out 3IP Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1W84A 2.2 Inactive in-in out-out L12 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ZB0A 2.1 Inactive in-in out-out GK3 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1M7QA 2.4 Inactive in-in out-out DQO Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1OUKA 2.5 Inactive in-in out-out 084 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1OUYA 2.5 Inactive in-in out-out 094 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1YQJA 2.0 Inactive in-out out-out 6NP Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3ZYAA 1.9 Inactive out-in none-out 2A8 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1OZ1A 2.1 Inactive in-in out-out FPH Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3FLQA 1.9 Inactive in-in out-out 891 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3FMJA 2.0 Inactive in-in out-out FMJ Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3FSFA 2.1 Inactive in-in none-out FSS Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1A9UA 2.5 Inactive in-in out-out SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BL6A 2.5 Inactive in-in out-out SB6 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 1BL7A 2.5 Inactive in-in out-out SB4 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3MPAA 2.1 Inactive in-in none-none SB2 Type1
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 2ZB1A 2.5 Inactive in-in none-out GK4 Type1.5_Back
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5XYXA 2.61 Inactive in-in none-out FTZ Type1.5_Back
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 5XYYA 1.7 Inactive in-in out-out P0F Type1.5_Back
Homo sapiens NEK NEK2 NEK2_HUMAN Serine/threonine-protein kinase Nek2 5M53A 1.9 Inactive out-out none-out 7GJ Type1
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4MWIA 1.7 Inactive in-in out-out PXN Allosteric
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6BWKA 2.79 Inactive in-none none-out No_ligand No_ligand
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 7JW7A 2.63 Inactive in-in none-out No_ligand No_ligand
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 8SLZA 2.3 Inactive in-in out-out No_ligand No_ligand
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 4M67A 1.9 Inactive in-in out-out No_ligand No_ligand
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK6A 2.41 Inactive in-in out-out No_ligand No_ligand
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 6LK5A 2.5 Inactive in-in out-out No_ligand No_ligand
Homo sapiens OTHER MLKL MLKL_HUMAN Mixed lineage kinase domain-like protein 5KO1A 2.16 Inactive in-in out-out 6UY Type1
Homo sapiens OTHER PIK3R4 PI3R4_HUMAN Phosphoinositide 3-kinase regulatory subunit 4 8SORA 3.96 Inactive out-out out-out ADP Type1
Homo sapiens OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VA 1.723 Inactive out-none out-out No_ligand No_ligand
Homo sapiens OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O1VB 1.723 Inactive out-none out-out No_ligand No_ligand
Homo sapiens OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2CA 2.4 Inactive out-none out-in No_ligand No_ligand
Homo sapiens OTHER WNK3 WNK3_HUMAN Serine/threonine-protein kinase WNK3 5O2BB 2.038 Inactive out-none out-none KS1 Type1
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8CHFE 4.25 Inactive out-out out-out No_ligand No_ligand
Homo sapiens STE MAP2K1 MP2K1_HUMAN Dual specificity mitogen-activated protein kinase kinase 1 8CHFF 4.25 Inactive out-out out-out No_ligand No_ligand
Homo sapiens STE STK10 STK10_HUMAN Serine/threonine-protein kinase 10 7QGPA 1.9 Inactive in-out out-out DJ8 Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3ZHPC 2.9 Inactive out-out out-out No_ligand No_ligand
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 3ZHPD 2.9 Inactive out-none out-out No_ligand No_ligand
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8BZIA 1.72 Inactive out-out none-none SJL Type1.5_Back
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8BZJA 2.52 Inactive out-out none-none SJX Type1.5_Back
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B30A 2.1 Inactive out-out none-none 59T Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B31A 1.8 Inactive out-out none-none SQ8 Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B32A 1.75 Inactive out-out none-none SQQ Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B33A 1.9 Inactive out-out none-none SQE Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B34A 2.1 Inactive out-out none-none SQK Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B35A 2.4 Inactive out-out none-none SQB Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 7B35B 2.4 Inactive out-out none-none SQB Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8BZJB 2.52 Inactive out-out none-none SJX Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLRA 1.85 Inactive out-out none-none VYN Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLRB 1.85 Inactive out-out none-none VYN Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLSA 1.61 Inactive out-out none-none VYH Type1.5_Front
Homo sapiens STE STK24 STK24_HUMAN Serine/threonine-protein kinase 24 8QLTA 1.47 Inactive out-out none-none VZ2 Type1.5_Front
Homo sapiens STE STK26 STK26_HUMAN Serine/threonine-protein kinase 26 7B36C 2.107 Inactive out-out none-out 59T Type1.5_Back
Homo sapiens STE STK26 STK26_HUMAN Serine/threonine-protein kinase 26 7B36A 2.107 Inactive out-out none-out 59T Type1.5_Front
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4A 2.42 Inactive out-out out-out No_ligand No_ligand
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4B 2.42 Inactive out-out none-out No_ligand No_ligand
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4C 2.42 Inactive in-in out-out No_ligand No_ligand
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LG4E 2.42 Inactive out-out out-out No_ligand No_ligand
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDA 3.05 Inactive out-out out-out ANP Type1
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDB 3.05 Inactive out-out out-out ANP Type1
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDC 3.05 Inactive out-out out-out ANP Type1
Homo sapiens STE STK3 STK3_HUMAN Serine/threonine-protein kinase 3 4LGDD 3.05 Inactive out-out out-out ANP Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 3SKCA 3.2 Inactive out-out none-out BR2 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4E26B 2.55 Inactive in-in in-out 734 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEA 3.0 Inactive out-out out-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEB 3.0 Inactive out-out out-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIEC 3.0 Inactive out-out none-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HIED 3.0 Inactive out-out none-out P06 Type1
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 7P3VA 2.37 Inactive out-out none-out 5I4 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 7P3VB 2.37 Inactive out-out out-out 5I4 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4CQEB 2.3 Inactive in-out none-out CQE Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2A 2.5 Inactive out-out none-out P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4XV2B 2.5 Inactive in-out none-out P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5CSWB 2.66 Inactive out-out none-none P06 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 6V2UB 3.78 Inactive out-out none-none P06 Type1.5_Back
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 2NRYA 2.15 Inactive in-in in-in STU Type1
Homo sapiens TKL IRAK4 IRAK4_HUMAN Interleukin-1 receptor-associated kinase 4 2NRYB 2.15 Inactive in-out in-in STU Type1
Homo sapiens TKL MAP3K12 M3K12_HUMAN Mitogen-activated protein kinase kinase kinase 12 5CENA 1.7 Inactive out-out out-out No_ligand No_ligand
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 2EVAA 2.0 Inactive in-in none-out ADN Type1
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 4GS6A 2.2 Inactive in-in none-out 1FM Type1
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 4L3PA 2.68 Inactive in-in none-in 1UH Type1
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5JGBA 2.8 Inactive in-none none-out 6JV Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 6S1FA 3.11 Inactive in-in out-out KRE Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 6S1FC 3.11 Inactive in-in out-out KRE Type1
Homo sapiens TKL RIPK2 RIPK2_HUMAN Receptor-interacting serine/threonine-protein kinase 2 5AR8B 2.79 Inactive out-out none-out XYW Type1.5_Back
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 7JXIC 3.0 Inactive out-out none-in 8BS Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 4RJ6A 2.7 Inactive in-in in-in 3R0 Type1
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 5EM6A 2.78 Inactive in-in in-in 5Q3 Type1.5_Back
Homo sapiens TYR EGFR EGFR_HUMAN Epidermal growth factor receptor 8A2DA 1.11 Inactive out-out none-in KXY Type3
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9WA 1.359 Inactive in-in none-in ANP Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9XA 1.427 Inactive in-in out-in DB8 Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9YA 1.228 Inactive in-in out-none 1N1 Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5I9ZA 1.698 Inactive in-in out-in 627 Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA0B 1.948 Inactive in-in out-in A5B Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA0C 1.948 Inactive in-in none-none A5B Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA3A 1.788 Inactive in-in out-in P17 Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NJZA 1.768 Inactive in-in none-in 8ZH Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK1A 1.548 Inactive in-in out-in 90N Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK2A 1.649 Inactive in-in out-in 8ZZ Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK4A 1.45 Inactive in-in out-in 90E Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK5A 1.329 Inactive in-in out-in 90K Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK6A 1.267 Inactive in-out out-in 90W Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK7A 1.889 Inactive in-in out-in 8ZZ Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NK9A 1.588 Inactive in-out out-in 912 Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKBA 1.5 Inactive in-in out-in 8ZT Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKCA 1.448 Inactive in-in out-in 90T Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKDA 1.408 Inactive in-in out-in 91K Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKEA 1.39 Inactive in-in out-in 90B Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKFA 1.099 Inactive in-out out-in 8ZN Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKGA 1.1 Inactive in-out out-in 8ZK Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKHA 1.29 Inactive in-in out-in 8ZQ Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5NKIA 1.675 Inactive in-in none-none 8ZW Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 8BK0A 1.7 Inactive in-in out-in QJI Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 7KJCA 2.3 Inactive in-in out-in ACP Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 7KJCB 2.3 Inactive in-in none-none ACP Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 7KJAA 1.75 Inactive in-in none-none ACP Type1
Homo sapiens TYR EPHA2 EPHA2_HUMAN Ephrin type-A receptor 2 5IA2A 1.619 Inactive in-out out-in L66 Type1.5_Back
Homo sapiens TYR EPHA7 EPHA7_HUMAN Ephrin type-A receptor 7 7EEFA 2.6 Inactive in-in none-in No_ligand No_ligand
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 6FNKA 1.049 Inactive in-in out-in DXK Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 6FNMA 1.157 Inactive in-in out-in 1N1 Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 4AW5A 2.33 Inactive in-in none-in 30K Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VWXA 1.65 Inactive in-in out-in 7X4 Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VWYA 1.65 Inactive in-in out-in 7X5 Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VWZA 1.65 Inactive in-in out-in 7X6 Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VX0A 2.1 Inactive in-in out-in 7X7 Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2VX1A 1.65 Inactive in-in out-in 7X8 Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2X9FA 1.75 Inactive in-in out-in X9F Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 4BB4A 1.65 Inactive in-in out-in 32W Type1
Homo sapiens TYR EPHB4 EPHB4_HUMAN Ephrin type-B receptor 4 2XVDA 1.7 Inactive in-in out-in AS6 Type1.5_Back
Homo sapiens TYR ERBB2 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 7PCDA 1.77 Inactive out-out out-in 70I Type1.5_Back
Homo sapiens TYR ERBB2 ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 7JXHA 3.27 Inactive out-out out-out VOY Type1.5_Back
Homo sapiens TYR FGFR1 FGFR1_HUMAN Fibroblast growth factor receptor 1 3KXXA 3.2 Inactive in-in in-in No_ligand No_ligand
Homo sapiens TYR FGFR2 FGFR2_HUMAN Fibroblast growth factor receptor 2 6V6QC 2.46 Inactive in-in in-in ACP Type1
Homo sapiens TYR IGF1R IGF1R_HUMAN Insulin-like growth factor 1 receptor 3QQUA 2.9 Inactive in-out out-in 01P Type1
Homo sapiens TYR LCK LCK_HUMAN Tyrosine-protein kinase Lck 3B2WA 2.3 Inactive in-in out-in 9NH Type1
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AVYA 2.31 Inactive out-out none-none S4E Type1
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7AW2A 2.1 Inactive out-out none-none S4W Type1.5_Front
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7OLSA 1.89 Inactive out-out none-none VJZ Type1.5_Front
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7OLVA 2.13 Inactive out-out none-none VK2 Type1.5_Front
Homo sapiens TYR MERTK MERTK_HUMAN Tyrosine-protein kinase Mer 7OLXA 1.98 Inactive out-out none-none VK5 Type1.5_Front
Homo sapiens TYR MET MET_HUMAN Hepatocyte growth factor receptor 3Q6UA 1.6 Inactive in-out none-in AME Allosteric
Homo sapiens TYR PTK2 FAK1_HUMAN Focal adhesion kinase 1 2IJMB 2.187 Inactive in-out none-out ADP Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 1FMKA 1.5 Inactive out-out out-out No_ligand No_ligand
Mus musculus CAMK BRSK2 BRSK2_MOUSE Serine/threonine-protein kinase BRSK2 4YNZA 2.0 Inactive out-out out-none No_ligand No_ligand
Mus musculus CAMK BRSK2 BRSK2_MOUSE Serine/threonine-protein kinase BRSK2 4YNZB 2.0 Inactive out-out out-none No_ligand No_ligand
Mus musculus CAMK BRSK2 BRSK2_MOUSE Serine/threonine-protein kinase BRSK2 4YOMB 2.49 Inactive out-out out-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8VA 1.479 Inactive in-in none-out SLV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8WA 1.5 Inactive in-in out-out JND Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8XA 1.73 Inactive in-in out-out SLY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R93A 1.489 Inactive in-in none-out SOJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R94A 1.45 Inactive in-in none-out SOV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R95A 1.59 Inactive in-in none-out SQ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R96A 1.767 Inactive in-in none-out SQ7 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R98A 1.68 Inactive in-in out-out SQG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9AA 1.53 Inactive in-in out-out SQM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9BA 1.657 Inactive in-in none-out JGM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9GA 1.73 Inactive in-in out-out RGY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9HA 1.49 Inactive in-in none-out SQV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9OA 1.6 Inactive in-in out-out 54F Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9SA 1.7 Inactive in-in out-out A9B Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9TA 1.8 Inactive in-in out-out 6T5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9VA 1.45 Inactive in-in out-out SSY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9XA 1.72 Inactive in-in out-out NZ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9ZA 1.66 Inactive in-in out-out AYS Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA3A 1.57 Inactive in-in out-out SVD Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA4A 1.59 Inactive in-in out-out SVG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA5A 1.54 Inactive in-in out-out SVJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOIA 1.55 Inactive in-in none-out LOK Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO1A 1.66 Inactive in-in none-out LO5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO2A 1.6 Inactive in-in none-out JGG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO4A 1.51 Inactive in-in none-out LO8 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SODA 1.87 Inactive in-none none-out LOE Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOTA 1.54 Inactive in-in none-out LOQ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9MA 1.809 Inactive in-in none-out A7K A7K Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 1LEWA 2.3 Inactive in-in out-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 1LEZA 2.3 Inactive in-in out-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4KA3A 2.707 Inactive in-in none-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P4KA 2.304 Inactive in-in none-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5UOJA 2.1 Inactive out-out none-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TAAA 2.6 Inactive in-out out-out 87B Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R90A 1.619 Inactive in-in none-out SNJ Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R91A 1.731 Inactive in-in out-out SNV Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R92A 1.66 Inactive in-in none-out SO7 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R99A 1.89 Inactive in-in out-out SU7 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9CA 1.74 Inactive in-in out-out 7ZC Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9FA 1.986 Inactive in-in none-out SQP Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9IA 1.813 Inactive in-in none-out SQY Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9JA 1.52 Inactive in-in none-out LXS Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9LA 1.47 Inactive in-in none-out SRJ Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9NA 1.688 Inactive out-out out-out JFS Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9PA 1.72 Inactive in-in out-out SFY Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9RA 1.76 Inactive in-in out-out K3D Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9YA 1.57 Inactive in-in none-out SU7 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA0A 1.91 Inactive in-out out-out JFS Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA2A 1.57 Inactive in-in out-out SV4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA6A 1.86 Inactive in-in out-out SVM Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPB 2.049 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPC 2.049 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQA 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQB 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQC 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQD 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8UA 1.48 Inactive in-in out-out SLS Type1.5_Back
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA7A 1.92 Inactive in-in out-out SW7 Type1.5_Back
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA8A 1.78 Inactive in-in out-out 2O6 Type1.5_Back
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8YA 1.679 Inactive in-in out-out SMV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8ZA 1.65 Inactive in-in out-out SN4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R97A 1.438 Inactive in-in out-out RUY Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9DA 1.69 Inactive in-in out-out N9J Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9EA 1.775 Inactive in-in none-out S7S Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9KA 1.498 Inactive in-in out-out SR4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9QA 1.645 Inactive in-in out-out LVD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9WA 1.89 Inactive in-in out-out STV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA1A 1.61 Inactive in-in out-out PO6 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA9A 1.68 Inactive in-in out-out SWD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB 2.6 Inactive out-out out-out 87B ATP Type3 Allosteric
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4OW8A 2.03 Inactive out-out out-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FA 2.9 Inactive out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FB 2.9 Inactive out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FC 2.9 Inactive out-none none-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F61A 1.8 Inactive in-out none-none ADP Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIA 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIB 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIC 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORID 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORKA 1.6 Inactive in-out none-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORLA 2.9 Inactive in-out none-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORPA 2.1 Inactive out-out none-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORTA 1.9 Inactive out-out out-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORMA 2.5 Inactive in-out out-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3OROA 1.9 Inactive in-out out-out AGS NHE Type1 Allosteric
Rattus norvegicus OTHER MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZA 2.192 Inactive in-in none-out No_ligand No_ligand
Rattus norvegicus OTHER MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZB 2.192 Inactive in-in none-out No_ligand No_ligand
Rattus norvegicus OTHER WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6CN9B 1.8 Inactive out-none out-out No_ligand No_ligand
Rattus norvegicus OTHER WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 7UOSA 2.9 Inactive out-none out-out WIB Type1
Rattus norvegicus OTHER WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6OL2A 2.1 Inactive out-none out-out MU7 Type1.5_Back
Saccharomyces cerevisiae CAMK RAD53 RAD53_YEAST Serine/threonine-protein kinase RAD53 5XZWB 2.8 Inactive out-out none-out No_ligand No_ligand
Saccharomyces cerevisiae CAMK RAD53 RAD53_YEAST Serine/threonine-protein kinase RAD53 5XZVB 3.1 Inactive out-out none-out ANP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4A 1.95 Inactive out-out out-none No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4B 1.95 Inactive out-out none-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCA 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCB 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCC 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCD 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEA 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEB 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEC 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXED 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEE 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEF 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5A 2.0 Inactive out-out out-none ANP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5B 2.0 Inactive out-out none-out ANP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDA 2.75 Inactive out-out out-out ATP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDB 2.75 Inactive out-out none-out ATP Type1
Staphylococcus aureus OTHER PKNB A0A0H3JME9_STAAN Protein kinase 4EQMB 3.0 Inactive out-out out-none ANP Type1
Staphylococcus aureus OTHER PKNB A0A0H3JME9_STAAN Protein kinase 4EQMC 3.0 Inactive out-out out-none ANP Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 4YGAE 2.94 Inactive out-none out-out No_ligand No_ligand

Protein kinases with BLBminus conformation in complex with All ligands

Total number of genes: 17
Total number of chains: 141
AGC CAMK CK1 CMGC NEK RGC STE TKL TYR OTHER Representative
BLBminus 0 15 0 73 0 0 0 3 7 43 5R97A
Representatives from each kinase
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein name PDB Resolution Activity Label Chelix-SaltBridge ActloopNT-ActLoopCT Ligand Type
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTA 2.3 Inactive out-out out-out CPS Type1
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTB 2.3 Inactive out-out out-out CPS Type1
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUA 1.9 Inactive out-out out-out CPS Type1
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTC 2.3 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUB 1.9 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUC 1.9 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZUD 1.9 Inactive out-out out-out CPS CPS Type1 Allosteric
Arabidopsis thaliana CAMK CIPK23 CIPKN_ARATH CBL-interacting serine/threonine-protein kinase 23 4CZTD 2.3 Inactive out-out out-out CPS CPS CPS Type1 Allosteric Allosteric
Arabidopsis thaliana CAMK CIPK24 CIPKO_ARATH CBL-interacting serine/threonine-protein kinase 24 4D28C 3.3 Inactive out-out out-out No_ligand No_ligand
Arabidopsis thaliana CMGC MPK6 MPK6_ARATH Mitogen-activated protein kinase 6 5CI6A 3.0 Inactive in-out out-out No_ligand No_ligand
Arabidopsis thaliana OTHER BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68A 2.0 Inactive out-out out-in PDO Allosteric
Arabidopsis thaliana OTHER BIR2 BIR2_ARATH Inactive LRR receptor-like serine/threonine-protein kinase BIR2 4L68B 2.0 Inactive out-out out-out No_ligand No_ligand
Arabidopsis thaliana TKL SOBIR1 SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 7CTVA 2.886 Inactive out-none out-out ANP Type1
Arabidopsis thaliana TKL SOBIR1 SBIR1_ARATH Leucine-rich repeat receptor-like serine/threonine/tyrosine-protein kinase SOBIR1 7CTVB 2.886 Inactive out-none out-out ANP Type1
Dictyostelium discoideum TKL ROCO4 ROCO4_DICDI Probable serine/threonine-protein kinase roco4 4F0GA 2.0 Inactive in-in none-none No_ligand No_ligand
Equus caballus OTHER MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0A 2.746 Inactive in-in out-out No_ligand No_ligand
Equus caballus OTHER MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0B 2.746 Inactive in-in out-out No_ligand No_ligand
Equus caballus OTHER MLKL F6S337_HORSE Mixed lineage kinase domain like pseudokinase 6VC0C 2.746 Inactive in-in out-out No_ligand No_ligand
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3U51A 2.241 Inactive out-out none-out No_ligand No_ligand
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3U51B 2.241 Inactive out-out none-none No_ligand No_ligand
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3SVVA 2.204 Inactive in-in out-none VSP Type1.5_Back
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 3SVVB 2.204 Inactive in-in none-none VSP Type1.5_Back
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 4DGGA 2.65 Inactive out-none none-out I76 Type1.5_Front
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5J5SA 2.153 Inactive out-out none-none 6G3 Type1.5_Front
Gallus gallus TYR SRC SRC_CHICK Proto-oncogene tyrosine-protein kinase Src 5J5SB 2.153 Inactive out-out none-none 6G3 Type1.5_Front
Giardia intestinalis CMGC CDK A8BZ95_GIAIC Kinase, CMGC CDK 3GBZA 1.85 Inactive out-none out-none No_ligand No_ligand
Giardia intestinalis CMGC CDK A8BZ95_GIAIC Kinase, CMGC CDK 3GC0A 2.0 Inactive out-none out-out AMP Type1
Mus musculus CAMK BRSK2 BRSK2_MOUSE Serine/threonine-protein kinase BRSK2 4YNZA 2.0 Inactive out-out out-none No_ligand No_ligand
Mus musculus CAMK BRSK2 BRSK2_MOUSE Serine/threonine-protein kinase BRSK2 4YNZB 2.0 Inactive out-out out-none No_ligand No_ligand
Mus musculus CAMK BRSK2 BRSK2_MOUSE Serine/threonine-protein kinase BRSK2 4YOMB 2.49 Inactive out-out out-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8VA 1.479 Inactive in-in none-out SLV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8WA 1.5 Inactive in-in out-out JND Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8XA 1.73 Inactive in-in out-out SLY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R93A 1.489 Inactive in-in none-out SOJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R94A 1.45 Inactive in-in none-out SOV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R95A 1.59 Inactive in-in none-out SQ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R96A 1.767 Inactive in-in none-out SQ7 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R98A 1.68 Inactive in-in out-out SQG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9AA 1.53 Inactive in-in out-out SQM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9BA 1.657 Inactive in-in none-out JGM Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9GA 1.73 Inactive in-in out-out RGY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9HA 1.49 Inactive in-in none-out SQV Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9OA 1.6 Inactive in-in out-out 54F Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9SA 1.7 Inactive in-in out-out A9B Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9TA 1.8 Inactive in-in out-out 6T5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9VA 1.45 Inactive in-in out-out SSY Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9XA 1.72 Inactive in-in out-out NZ4 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9ZA 1.66 Inactive in-in out-out AYS Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA3A 1.57 Inactive in-in out-out SVD Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA4A 1.59 Inactive in-in out-out SVG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA5A 1.54 Inactive in-in out-out SVJ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOIA 1.55 Inactive in-in none-out LOK Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO1A 1.66 Inactive in-in none-out LO5 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO2A 1.6 Inactive in-in none-out JGG Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SO4A 1.51 Inactive in-in none-out LO8 Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SODA 1.87 Inactive in-none none-out LOE Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 6SOTA 1.54 Inactive in-in none-out LOQ Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9MA 1.809 Inactive in-in none-out A7K A7K Allosteric Allosteric
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 1LEWA 2.3 Inactive in-in out-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 1LEZA 2.3 Inactive in-in out-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4KA3A 2.707 Inactive in-in none-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 3P4KA 2.304 Inactive in-in none-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5UOJA 2.1 Inactive out-out none-out No_ligand No_ligand
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TAAA 2.6 Inactive in-out out-out 87B Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R90A 1.619 Inactive in-in none-out SNJ Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R91A 1.731 Inactive in-in out-out SNV Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R92A 1.66 Inactive in-in none-out SO7 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R99A 1.89 Inactive in-in out-out SU7 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9CA 1.74 Inactive in-in out-out 7ZC Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9FA 1.986 Inactive in-in none-out SQP Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9IA 1.813 Inactive in-in none-out SQY Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9JA 1.52 Inactive in-in none-out LXS Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9LA 1.47 Inactive in-in none-out SRJ Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9NA 1.688 Inactive out-out out-out JFS Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9PA 1.72 Inactive in-in out-out SFY Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9RA 1.76 Inactive in-in out-out K3D Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9YA 1.57 Inactive in-in none-out SU7 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA0A 1.91 Inactive in-out out-out JFS Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA2A 1.57 Inactive in-in out-out SV4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA6A 1.86 Inactive in-in out-out SVM Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPB 2.049 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOPC 2.049 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQA 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQB 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQC 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 4LOQD 2.319 Inactive in-in out-out SB4 Type1
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8UA 1.48 Inactive in-in out-out SLS Type1.5_Back
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA7A 1.92 Inactive in-in out-out SW7 Type1.5_Back
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA8A 1.78 Inactive in-in out-out 2O6 Type1.5_Back
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8YA 1.679 Inactive in-in out-out SMV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R8ZA 1.65 Inactive in-in out-out SN4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R97A 1.438 Inactive in-in out-out RUY Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9DA 1.69 Inactive in-in out-out N9J Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9EA 1.775 Inactive in-in none-out S7S Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9KA 1.498 Inactive in-in out-out SR4 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9QA 1.645 Inactive in-in out-out LVD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5R9WA 1.89 Inactive in-in out-out STV Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA1A 1.61 Inactive in-in out-out PO6 Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 5RA9A 1.68 Inactive in-in out-out SWD Type3
Mus musculus CMGC MAPK14 MK14_MOUSE Mitogen-activated protein kinase 14 7Z9TBBB 2.6 Inactive out-out out-out 87B ATP Type3 Allosteric
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4OW8A 2.03 Inactive out-out out-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FA 2.9 Inactive out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FB 2.9 Inactive out-none out-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNA PKNA_MYCTU Serine/threonine-protein kinase PknA 4X3FC 2.9 Inactive out-none none-out No_ligand No_ligand
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3F61A 1.8 Inactive in-out none-none ADP Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIA 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIB 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORIC 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORID 2.0 Inactive in-out out-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORKA 1.6 Inactive in-out none-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORLA 2.9 Inactive in-out none-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORPA 2.1 Inactive out-out none-out AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORTA 1.9 Inactive out-out out-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3ORMA 2.5 Inactive in-out out-none AGS Type1
Mycobacterium tuberculosis OTHER PKNB PKNB_MYCTU Serine/threonine-protein kinase PknB 3OROA 1.9 Inactive in-out out-out AGS NHE Type1 Allosteric
Rattus norvegicus OTHER MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZA 2.192 Inactive in-in none-out No_ligand No_ligand
Rattus norvegicus OTHER MLKL D3ZKP6_RAT Mixed lineage kinase domain like pseudokinase 6VBZB 2.192 Inactive in-in none-out No_ligand No_ligand
Rattus norvegicus OTHER WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6CN9B 1.8 Inactive out-none out-out No_ligand No_ligand
Rattus norvegicus OTHER WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 7UOSA 2.9 Inactive out-none out-out WIB Type1
Rattus norvegicus OTHER WNK1 WNK1_RAT Serine/threonine-protein kinase WNK1 6OL2A 2.1 Inactive out-none out-out MU7 Type1.5_Back
Saccharomyces cerevisiae CAMK RAD53 RAD53_YEAST Serine/threonine-protein kinase RAD53 5XZWB 2.8 Inactive out-out none-out No_ligand No_ligand
Saccharomyces cerevisiae CAMK RAD53 RAD53_YEAST Serine/threonine-protein kinase RAD53 5XZVB 3.1 Inactive out-out none-out ANP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4A 1.95 Inactive out-out out-none No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY4B 1.95 Inactive out-out none-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCA 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCB 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCC 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYCD 3.0 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEA 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEB 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEC 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXED 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEE 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZXEF 2.6 Inactive out-out out-out No_ligand No_ligand
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5A 2.0 Inactive out-out out-none ANP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZY5B 2.0 Inactive out-out none-out ANP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDA 2.75 Inactive out-out out-out ATP Type1
Saccharomyces cerevisiae OTHER GCN2 GCN2_YEAST eIF-2-alpha kinase GCN2 1ZYDB 2.75 Inactive out-out none-out ATP Type1
Staphylococcus aureus OTHER PKNB A0A0H3JME9_STAAN Protein kinase 4EQMB 3.0 Inactive out-out out-none ANP Type1
Staphylococcus aureus OTHER PKNB A0A0H3JME9_STAAN Protein kinase 4EQMC 3.0 Inactive out-out out-none ANP Type1
Toxoplasma gondii CAMK CDPK1 Q9BJF5_TOXGO Calmodulin-domain protein kinase 1 4YGAE 2.94 Inactive out-none out-out No_ligand No_ligand