| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGinter | None | in-out | out-in | STI 1N1 | Allosteric Type1 | 233 - 498 | 13 |
| B | Active | DFGin | BLAminus | in-in | in-in | STI 1N1 | Allosteric Type1 | 233 - 498 | 0 |
| C | Inactive | DFGinter | None | in-none | out-in | STI 1N1 | Allosteric Type1 | 234 - 499 | 5 |
Representative sequence - Chain C
238 248 258 268
spnydKWEME RTDITMKHKL gggqygeVYE GVWkkyslTV
278 288 298 308
AVKTlkedtm EVEEFLKEAA VMKEIKHPNL VQLLgvctre
318 328 338 348
ppfyIITEFM TYGNLLDYLR ECNRQEVNAV VLLYMATQIS
358 368 378 388
SAMEYLEKKN FIHRDLAARN CLVGENHLVK VADFGLSRLM
398 408 418 428
TGDTYTAhag akFPIKWTAP ESLAYNKFSI KSDVWAFGVL
438 448 458 468
LWEIATYGMS PYPGIDLSQV YELLEKDYRM ERPEGCPEKV
478 488 498
YELMRACWQW NPSDRPSFAE IHQAFETMFQ E