Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLBplus | 6 | 6X3OA |
Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
---|---|---|---|---|---|---|---|---|---|---|---|---|
TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3NA | 1.95 | Inactive | DFGin | BLBplus | out-out | none-in | ULV 5WE | Type1 Allosteric |
TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 5FBOA | 1.894 | Inactive | DFGin | BLBplus | out-out | none-out | 5WH 5WE | Type1.5_Back Allosteric |
TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 5FBNC | 1.8 | Inactive | DFGin | BLBplus | out-out | out-out | 5WF 5WE | Type1.5_Front Allosteric |
TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3OA | 1.9 | Inactive | DFGin | BLBplus | out-out | out-out | ULY 5WE | Type1.5_Front Allosteric |
TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3OB | 1.9 | Inactive | DFGin | BLBplus | out-out | out-out | ULY 5WE | Type1.5_Front Allosteric |
TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 5FBND | 1.8 | Inactive | DFGin | BLBplus | out-out | out-in | 5WF 5WE 5WE 5WE | Type1.5_Front Allosteric Allosteric Allosteric |
Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLBplus | 6 | 6X3OA |
Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3NA | 1.95 | Inactive | DFGin | BLBplus | out-out | none-in | ULV 5WE | Type1 Allosteric |
Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 5FBOA | 1.894 | Inactive | DFGin | BLBplus | out-out | none-out | 5WH 5WE | Type1.5_Back Allosteric |
Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 5FBNC | 1.8 | Inactive | DFGin | BLBplus | out-out | out-out | 5WF 5WE | Type1.5_Front Allosteric |
Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3OA | 1.9 | Inactive | DFGin | BLBplus | out-out | out-out | ULY 5WE | Type1.5_Front Allosteric |
Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 6X3OB | 1.9 | Inactive | DFGin | BLBplus | out-out | out-out | ULY 5WE | Type1.5_Front Allosteric |
Homo sapiens | TYR | BTK | BTK_HUMAN | Tyrosine-protein kinase BTK | 5FBND | 1.8 | Inactive | DFGin | BLBplus | out-out | out-in | 5WF 5WE 5WE 5WE | Type1.5_Front Allosteric Allosteric Allosteric |
Spatial | Dihedral | Chains | Representative |
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Organism | Group | Gene | UniprotID | Protein | PDB | Resolu | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type |
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