PRKG1 (cGMP-dependent protein kinase 1)

Group: AGC

Uniprot: KGP1_HUMAN

Domain boundary: 360 - 619

Total number of chains: 18

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	12	AF-Q13976-K1A
DFGin	ABAminus	6	7T4UA

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
7T4UA	1.99	Inactive	DFGin	ABAminus	in-in	in-in	EX6	Allosteric	205 - 671	None	X517	0
7T4UB	1.99	Inactive	DFGin	ABAminus	in-in	in-in	EX6	Allosteric	205 - 671	None	X517	0
7T4WA	2.23	Inactive	DFGin	ABAminus	in-in	in-in	EZJ	Allosteric	205 - 671	None	X517	0
7T4WB	2.23	Inactive	DFGin	ABAminus	in-in	in-in	EZJ	Allosteric	205 - 671	None	X517	0
7T4TA	2.08	Inactive	DFGin	ABAminus	in-in	in-in	PCG ATP	Allosteric Type1	204 - 671	None	X517	0
7T4TB	2.08	Inactive	DFGin	ABAminus	in-in	in-in	PCG ATP	Allosteric Type1	204 - 671	None	X517	0
7T4VA	2.28	Inactive	DFGin	BLAminus	in-in	in-out	EXZ	Allosteric	205 - 671	None	X517	0
7T4VB	2.28	Active	DFGin	BLAminus	in-in	in-in	EXZ	Allosteric	205 - 671	None	X517	0
AF-Q13976-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	352 - 627	None	None	0
6BDLA	1.96	Inactive	DFGin	BLAminus	in-in	in-out	No_ligand	No_ligand	337 - 671	None	X517	0
6BDLB	1.96	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	337 - 671	None	X517	0
6BG2A	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	336 - 671	None	X517	0
6BG2B	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	346 - 671	None	X517	0
6BG2C	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	337 - 671	None	X517	0
6BG2D	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	344 - 671	None	X517	0
7LV3A	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	57 - 671	None	X517	0
7LV3B	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	58 - 671	None	X517	0
6C0TA	1.98	Active	DFGin	BLAminus	in-in	in-in	EE4	Type1.5_Front	337 - 671	None	X517	0

PRKG1 (cGMP-dependent protein kinase 1)

Group: AGC

Total number of chains: 18

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	12	AF-Q13976-K1A
DFGin	ABAminus	6	7T4UA

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	KGP1_HUMAN	7T4UA	1.99	Inactive	DFGin	ABAminus	in-in	in-in	EX6	Allosteric	205 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4UB	1.99	Inactive	DFGin	ABAminus	in-in	in-in	EX6	Allosteric	205 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4WA	2.23	Inactive	DFGin	ABAminus	in-in	in-in	EZJ	Allosteric	205 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4WB	2.23	Inactive	DFGin	ABAminus	in-in	in-in	EZJ	Allosteric	205 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4TA	2.08	Inactive	DFGin	ABAminus	in-in	in-in	PCG ATP	Allosteric Type1	204 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4TB	2.08	Inactive	DFGin	ABAminus	in-in	in-in	PCG ATP	Allosteric Type1	204 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4VA	2.28	Inactive	DFGin	BLAminus	in-in	in-out	EXZ	Allosteric	205 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7T4VB	2.28	Active	DFGin	BLAminus	in-in	in-in	EXZ	Allosteric	205 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	AF-Q13976-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	352 - 627	None	None	0
Homo sapiens	KGP1_HUMAN	6BDLA	1.96	Inactive	DFGin	BLAminus	in-in	in-out	No_ligand	No_ligand	337 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	6BDLB	1.96	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	337 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	6BG2A	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	336 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	6BG2B	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	346 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	6BG2C	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	337 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	6BG2D	1.83	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	344 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7LV3A	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	57 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	7LV3B	2.41	Active	DFGin	BLAminus	in-in	in-in	ANP	Type1	58 - 671	None	X517	0
Homo sapiens	KGP1_HUMAN	6C0TA	1.98	Active	DFGin	BLAminus	in-in	in-in	EE4	Type1.5_Front	337 - 671	None	X517	0

PRKG1 (cGMP-dependent protein kinase 1)

No non-human structures known.