6EMH

MAPK10 (Mitogen-activated protein kinase 10)
Group: CMGC
Uniprot: MK10_HUMAN
Organism: Homo sapiens
Domain boundary: 64 - 359
Resolu: 1.76

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in out-out BGE C15 Type1 Allosteric 46 - 400 5
B Inactive DFGin ABAminus in-in out-out BGE C15 Type1 Allosteric 46 - 400 5
C Inactive DFGin ABAminus in-in out-out BGE Type1 46 - 400 10
D Inactive DFGin ABAminus in-in out-none BGE Type1 46 - 400 11
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        45         55         65         75 
ggsmskskvd NQFYSVEVGD STFTVLKRYQ NLKPIgsgaq 
        85         95        105        115 
GIVCAAYDAV LDRNVAIKKL SRPFQNQTHA KRAYRELVLM 
       125        135        145        155 
KCVNHKNIIS LLNVFTPQKT LEEFQDVYLV MELMDANLCQ 
       165        175        185        195 
VIQMELDHER MSYLLYQMLC GIKHLHSAGI IHRDLKPSNI 
       205        215        225        235 
VVKSDCTLKI LDFGLARTAg tsfmmtpyvv TRYYRAPEVI 
       245        255        265        275 
LGMGYKENVD IWSVGCIMGE MVRHKILFPG RDYIDQWNKV 
       285        295        305        315 
IEQLGTPCPE FMKKLQPTVR NYVENRPKYA GLTFPKLFPD 
       325        335        345        355 
SLFPADSEHN KLKASQARDL LSKMLVIDPA KRISVDDALQ 
       365        375        385        395 
HPYINVWYDP AEVEAPPPQI ydkqlderEH TIEEWKELIY 

KEVMNse
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None