4MWI

MLKL (Mixed lineage kinase domain-like protein)
Pseudokinase
Group: OTHER
Uniprot: MLKL_HUMAN
Organism: Homo sapiens
Domain boundary: 201 - 468
Resolu: 1.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBminus in-in out-out PXN Allosteric 193 - 470 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       187        197        207        217 
gamgskcmqe ipqeqIKEIK KEQLSGSPWI LLRENEVSTL 
       227        237        247        257 
YKGEYHRAPV AIKVFKKLQA GSIAIVRQTF NKEIKTMKKF 
       267        277        287        297 
ESPNILRIFG ICIDETVTPP QFSIVMEYCE LGTLRELLDR 
       307        317        327        337 
EKDLTLGKRM VLVLGAARGL YRLHHSEAPE LHGKIRSSNF 
       347        357        367        377 
LVTQGYQVKL AGFELRKTQt smslgttrek tDRVKSTAYL 
       387        397        407        417 
SPQELEDVFY QYDVKSEIYS FGIVLWEIAT GDIPFQGCNS 
       427        437        447        457 
EKIRKLVAVK RQQEPLGEDC PSELREIIDE CRAHDPSVRP 
       467 
SVDEILKKLS TFSk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None