| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | ABAminus | in-in | in-out | 1M3 1M3 | Allosteric Type1 | 842 - 1132 | 0 |
| B | Inactive | DFGin | ABAminus | in-in | in-out | 1M3 1M3 | Allosteric Type1 | 842 - 1132 | 0 |
| C | Inactive | DFGin | ABAminus | in-in | in-out | 1M3 1M3 | Type1 Allosteric | 842 - 1132 | 0 |
| D | Inactive | DFGin | ABAminus | in-in | in-out | 1M3 1M3 | Allosteric Type1 | 842 - 1132 | 0 |
Representative sequence - Chain D
840 850 860 870
gssgafedrd pTQFEERHLK FLQQLGKGNF GSVEMCRYDP
880 890 900 910
LQDNTGEVVA VKKLQHSTEE HLRDFEREIE ILKSLQHDNI
920 930 940 950
VKYKGVCYSA GRRNLKLIME YLPYGSLRDY LQKHKERIDH
960 970 980 990
IKLLQYTSQI CKGMEYLGTK RYIHRDLATR NILVENENRV
1000 1010 1020 1030
KIGDFGLTKV LPQDKEYYKV KEPGESPIFW YAPESLTESK
1040 1050 1060 1070
FSVASDVWSF GVVLYELFTY IEKSKSAPAE FMRMIGNDKQ
1080 1090 1100 1110
GQMIVFHLIE LLKNNGRLPR PDGCPDEIYM IMTECWNNNV
1120 1130
NQRPSFRDLA LRVDQIRDNM AG