Ligand: HVB

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6QAHA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 6QAHA 1.58 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii HVB, HVB Allosteric, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1
TKL ACVR1 ACVR1_HUMAN 5S7HA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HVB, HVB Type1, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1

Ligand: HVB

Total number of chains: 2
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 6QAHA
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_HUMAN 6QAHA 1.58 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_oiii HVB, HVB Allosteric, Allosteric 11 - 357 0 None None Mitogen-activated protein kinase 1 Homo sapiens
TKL ACVR1 ACVR1_HUMAN 5S7HA 1.3 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_nooi LU8, LU8, LU8, HVB, HVB Type1, Allosteric, Allosteric, Allosteric, Allosteric 201 - 499 0 None Q207D Activin receptor type-1 Homo sapiens

Ligand: HVB

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Advanced page

Hover over column headers for tooltip help

Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism