Ligand

Protein kinases in complex with HVK

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	6QA1A

Database table as tsv

Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	6QA1A	1.58	Inactive	DFGin	BLAminus	out-out	in-in	HVK HVK HVK HVK HVK HVK HVK	Allosteric Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	5S7MB	1.32	Inactive	DFGin	BLAminus	in-out	in-in	LU8 HVK	Type1 Allosteric
TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	5S7MA	1.32	Inactive	DFGin	BLAminus	in-out	in-in	LU8 LU8 HVK HVK	Type1 Allosteric Allosteric Allosteric

Protein kinases in complex with HVK

Total number of genes: 2

Total number of chains: 3

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	3	6QA1A

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type
Homo sapiens	CMGC	MAPK1	MK01_HUMAN	Mitogen-activated protein kinase 1	6QA1A	1.58	Inactive	DFGin	BLAminus	out-out	in-in	HVK HVK HVK HVK HVK HVK HVK	Allosteric Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens	TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	5S7MB	1.32	Inactive	DFGin	BLAminus	in-out	in-in	LU8 HVK	Type1 Allosteric
Homo sapiens	TKL	ACVR1	ACVR1_HUMAN	Activin receptor type-1	5S7MA	1.32	Inactive	DFGin	BLAminus	in-out	in-in	LU8 LU8 HVK HVK	Type1 Allosteric Allosteric Allosteric

Protein kinases in complex with HVK

Total number of genes: 0

Total number of chains: 0

Spatial	Dihedral	Chains	Representative

Database table as tsv

Organism	Group	Gene	UniprotID	Protein	PDB	Resolu	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type