Protein kinases in complex with BAX (Sorafenib)

Total number of genes: 4
Total number of chains: 10
Spatial Dihedral Chains Representative
DFGout BBAminus 10 3WZEA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 3RGFA 2.2 Inactive DFGout BBAminus in-out out-out BAX Type2
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCSA 2.1 Inactive DFGout BBAminus in-out none-none BAX Type2
CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HEGA 2.2 Inactive DFGout BBAminus in-in none-out BAX Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HI2A 2.512 Inactive DFGout BBAminus in-in none-none BAX Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWJA 3.5 Inactive DFGout BBAminus in-in out-out BAX Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWJB 3.5 Inactive DFGout BBAminus in-in out-out BAX Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWHA 2.95 Inactive DFGout BBAminus in-in out-out BAX Type2
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWHB 2.95 Inactive DFGout BBAminus in-in out-out BAX Type2
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3WZEA 1.9 Inactive DFGout BBAminus in-in out-out BAX Type2
TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4ASDA 2.03 Inactive DFGout BBAminus in-in out-in BAX Type2

Protein kinases in complex with BAX

Total number of genes: 4
Total number of chains: 10
Spatial Dihedral Chains Representative
DFGout BBAminus 10 3WZEA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK8 CDK8_HUMAN Cyclin-dependent kinase 8 3RGFA 2.2 Inactive DFGout BBAminus in-out out-out BAX Type2
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3GCSA 2.1 Inactive DFGout BBAminus in-out none-none BAX Type2
Homo sapiens CMGC MAPK14 MK14_HUMAN Mitogen-activated protein kinase 14 3HEGA 2.2 Inactive DFGout BBAminus in-in none-out BAX Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 5HI2A 2.512 Inactive DFGout BBAminus in-in none-none BAX Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWJA 3.5 Inactive DFGout BBAminus in-in out-out BAX Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWJB 3.5 Inactive DFGout BBAminus in-in out-out BAX Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWHA 2.95 Inactive DFGout BBAminus in-in out-out BAX Type2
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 1UWHB 2.95 Inactive DFGout BBAminus in-in out-out BAX Type2
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 3WZEA 1.9 Inactive DFGout BBAminus in-in out-out BAX Type2
Homo sapiens TYR KDR VGFR2_HUMAN Vascular endothelial growth factor receptor 2 4ASDA 2.03 Inactive DFGout BBAminus in-in out-in BAX Type2

Protein kinases in complex with BAX

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type