TKL_ACVR2B (Activin receptor type-2B)

Total number of chains: 3
Active chains: 3
Uniprot: AVR2B_HUMAN
Kinase Domain Residues: 190 - 480
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q13705-K1A

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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q13705-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B
AF-Q13705-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B
2QLUA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 190 - 484 0 None None Activin receptor type-2B

TKL_ACVR2B (Activin receptor type-2B)

Total number of chains: 3
Active chains: 3
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% AF-Q13705-K1A

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
AVR2B_HUMAN AF-Q13705-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B Homo sapiens
AVR2B_HUMAN AF-Q13705-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 182 - 488 0 None None Activin receptor type-2B Homo sapiens
AVR2B_HUMAN 2QLUA 2.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii ADE Type1 190 - 484 0 None None Activin receptor type-2B Homo sapiens

TKL_ACVR2B (Activin receptor type-2B)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative

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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism