All / BBAminus / All

Total number of chains: 609
Active chains: 0
Total number of genes: 69
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 609 100.0% 5HG8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AGC AKT1 AKT1_HUMAN 8UVYA 2.11 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaiii APEdist_iiio XOO Allosteric 3 - 439 0 None E17K RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 8UW2A 2.2 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaioi APEdist_oooo XOO Allosteric 4 - 437 0 None None RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 8UW9A 1.9 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaiii APEdist_iiio XQ2 Allosteric 3 - 428 0 None None RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 8UW7A 1.972 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno XOO Allosteric 3 - 439 0 None None RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 3O96A 2.7 Inactive DFGout‑BBAminus none-none out-none nonTYR APEdihe_aannn APEdist_nnnn IQO Allosteric 2 - 429 0 None None RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 6HHHA 2.7 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaooi APEdist_nnno G4Q Allosteric 2 - 439 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 6HHJA 2.3 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo G4H Allosteric 3 - 444 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 6S9WA 2.3 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo L1Z Allosteric 3 - 444 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase
AGC AKT1 AKT1_HUMAN 4EJNA 2.19 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaiii APEdist_oioo 0R4 Type1 4 - 438 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 9C1WA 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XOO Allosteric 3 - 440 0 None P115A,G116A RAC-beta serine/threonine-protein kinase
AGC AKT2 AKT2_HUMAN 8Q61A 2.32 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn K06 Type3 1 - 435 0 None N2D RAC-beta serine/threonine-protein kinase
AGC PDPK1 PDPK1_HUMAN 3NAXA 1.75 Inactive DFGout‑BBAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn MP7 Type2 76 - 360 0 None None 3-phosphoinositide-dependent protein kinase 1
AGC PDPK1 PDPK1_HUMAN 3QC4A 1.8 Inactive DFGout‑BBAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii MP7 Type2 76 - 359 0 SEP241 E303A,K304A 3-phosphoinositide-dependent protein kinase 1
AGC ROCK2 ROCK2_HUMAN 9JCUA 3.02 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 27 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 9JCUC 3.02 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 27 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8GDSA 2.71 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nooo Z8O Type1 24 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8GDSB 2.71 Inactive DFGout‑BBAminus out-none in-out nonTYR APEdihe_aaiii APEdist_nooo Z8O Type1 24 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8GDSC 2.71 Inactive DFGout‑BBAminus out-none in-out nonTYR APEdihe_aaioi APEdist_nnno Z8O Type1 24 - 417 0 None None Rho-associated protein kinase 2
AGC ROCK2 ROCK2_HUMAN 8GDSD 2.71 Inactive DFGout‑BBAminus out-none in-none nonTYR APEdihe_aaiii APEdist_nnii Z8O Type1.5_Front 24 - 417 0 None None Rho-associated protein kinase 2
CAMK AURKA AURKA_HUMAN 2C6EA 2.1 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno HPM Type1.5_Back 127 - 389 0 None None Aurora kinase A
CAMK MKNK1 MKNK1_HUMAN 2HW6A 2.5 Inactive DFGout‑BBAminus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 39 - 376 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
CAMK MKNK1 MKNK1_HUMAN 2HW6B 2.5 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 375 0 None None MAP kinase-interacting serine/threonine-protein kinase 1
CAMK MKNK2 MKNK2_HUMAN 2AC3A 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 72 - 369 0 None None MAP kinase-interacting serine/threonine-protein kinase 2
CAMK PRKAA2 AAPK2_HUMAN 2H6DA 1.85 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2
CAMK PRKAA2 AAPK2_HUMAN 2YZAA 3.02 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2
CK1 CSNK1E KC1E_HUMAN 4HNIA 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 3 - 293 0 None None Casein kinase I isoform epsilon
CK1 CSNK1E KC1E_HUMAN 4HNIB 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 1 - 293 0 None None Casein kinase I isoform epsilon
CMGC CDK16 CDK16_HUMAN 5G6VA 2.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo 919 Type2 163 - 474 0 None S319D Cyclin-dependent kinase 16
CMGC CDK6 CDK6_HUMAN 1G3NA 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK6 CDK6_HUMAN 1G3NE 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6
CMGC CDK8 CDK8_HUMAN 3RGFA 2.2 Inactive DFGout‑BBAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 1 - 353 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F6UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnio 0SR Type2 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F6WA 2.39 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 0SS Type2 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F7LA 2.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 0SO Type2 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F7NA 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnio 0SV Type2 1 - 361 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 5HVYA 2.39 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oioo 66X Type2 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 6TPAA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn NZ8, NZ5, NZ5, NZ5 Type2, Allosteric, Allosteric, Allosteric 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F6SA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0SQ Type3 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN 4F7JA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0SU Type3 1 - 359 0 None None Cyclin-dependent kinase 8
CMGC MAPK11 MK11_HUMAN 3GP0A 1.9 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno NIL Type2 5 - 348 0 None None Mitogen-activated protein kinase 11
CMGC MAPK13 MK13_HUMAN 4EYJA 2.102 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno N61 Type2 2 - 351 0 None None Mitogen-activated protein kinase 13
CMGC MAPK14 MK14_HUMAN 9CJ3A 1.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo PDO, A1AWV Allosteric, Type2 4 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6QDZA 1.73 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno I46, HYK Allosteric, Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6QE1A 1.85 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno I46, HYW Allosteric, Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GCQA 2.0 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 1BU Type2 4 - 355 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GCSA 2.1 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aanii APEdist_nnnn BAX Type2 5 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GCVA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo SS6 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV3A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno R49 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFEA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z84 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFFA 1.5 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z83 Type2 5 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3PG3A 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno DG7 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6SFIA 1.6 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno LB5 Type2 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6SFJA 1.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo LBB Type2 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6SFOA 1.75 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno LBE Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 6ZWPA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno OE8 Type2 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3CTQA 1.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 337 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 5MZ3A 2.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 8EN Type2 4 - 353 0 None C162S Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HEGA 2.2 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BAX Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1W83A 2.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L11 Type2 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1WBNA 2.4 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L09 Type2 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3D83A 1.9 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK6 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 9CJ4A 1.8 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo B96 Type2 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GCUA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R48 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GCUB 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R48 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV4A 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo L51 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV4B 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo L51 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV5A 2.25 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R24 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV5B 2.25 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R24 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV6A 1.95 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno R39 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2BAKA 2.2 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno AQZ Type2 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4A9YA 2.2 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno AQZ Type2 5 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 4AA0A 1.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno AA0 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3E93A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 19B Type2 4 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3KQ7A 1.8 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo KQ7 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3GI3A 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno B10 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3IW8A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno HIZ Type3 4 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFBA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z87 Type3 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3LFCA 2.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z86 Type3 4 - 354 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNVA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 437 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3NNXA 2.28 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nioo EDD Type3 5 - 352 0 PTR182 None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1W82A 2.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L10 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 1WBVA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo LI3 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3HV7A 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1AU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2BAJA 2.25 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iooo 1PP Type3 2 - 353 0 None None Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3O8UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169Y Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3OBJA 2.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169R Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 3K3IA 1.7 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno JZJ, I46, I46 Type3, Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14
NEK NEK7 NEK7_HUMAN 8WS0B 2.12 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 19 - 299 0 None S195D Serine/threonine-protein kinase Nek7
NEK NEK7 NEK7_HUMAN 8WS1B 2.4 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 20 - 300 0 None D161N Serine/threonine-protein kinase Nek7
OTHER EIF2AK3 E2AK3_HUMAN 4X7JA 2.3 Inactive DFGout‑BBAminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 3Z1 Type1 585 - 1086 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7KA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z3 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7LA 1.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z4 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER EIF2AK3 E2AK3_HUMAN 4X7NA 2.35 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z5 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3
OTHER ULK3 ULK3_HUMAN 6FDZU 2.55 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo C87 Type1 8 - 274 0 None None Serine/threonine-protein kinase ULK3
STE MAP2K7 MP2K7_HUMAN 6YG7A 2.2 Inactive DFGout‑BBAminus na-na none-out nonTYR APEdihe_aanao APEdist_nnnn OQ2 Type2 102 - 403 0 None S271D,T275D Dual specificity mitogen-activated protein kinase kinase 7
STE MAP2K7 MP2K7_HUMAN 6YG7B 2.2 Inactive DFGout‑BBAminus na-na none-out nonTYR APEdihe_aaiao APEdist_nnno OQ2 Type2 103 - 403 0 None S271D,T275D Dual specificity mitogen-activated protein kinase kinase 7
STE MAP3K2 M3K2_HUMAN 9P6AA 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo 0LI Type2 351 - 617 0 None None Mitogen-activated protein kinase kinase kinase 2
STE MAP4K1 M4K1_HUMAN 7M0KA 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0KB 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 8 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0KC 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 8 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0KD 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0LA 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0LB 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 7 - 291 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0LC 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 5 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 7M0LD 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8XN7A 2.65 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo A1LVT Type1 6 - 292 0 None T165E,S171E Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 8XN7B 2.65 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo A1LVT Type1 6 - 293 0 None T165E,S171E Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 6NG0B 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo B49 Type1 7 - 293 0 None T165E,S171E Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 9BIKA 2.25 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_oooo A1APO Type1 6 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K1 M4K1_HUMAN 9N7RB 2.13 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo A1BWC Type1 8 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1
STE MAP4K4 M4K4_HUMAN 4U3YB 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 8 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4
STE PAK1 PAK1_HUMAN 4ZJIA 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJIB 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 540 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJIC 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 250 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJID 1.99 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 253 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJA 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 249 - 539 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJB 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 251 - 539 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJC 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 4OR Type3 251 - 542 0 None None Serine/threonine-protein kinase PAK 1
STE PAK1 PAK1_HUMAN 4ZJJD 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_oooo 4OR Type3 252 - 541 0 None None Serine/threonine-protein kinase PAK 1
STE PAK2 PAK2_HUMAN 9M41A 3.02 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 85 - 520 0 None K278R,D368N Serine/threonine-protein kinase PAK 2
STE SLK SLK_HUMAN 8BEMD 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase
STE SLK SLK_HUMAN 8BEMG 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase
STE SLK SLK_HUMAN 8BEMA 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 309 0 None None STE20-like serine/threonine-protein kinase
STE SLK SLK_HUMAN 8BEMB 2.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 310 0 None None STE20-like serine/threonine-protein kinase
STE STK10 STK10_HUMAN 6GTTA 2.25 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanio APEdist_nnnn B96 Type2 18 - 316 0 None None Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 6EIMA 1.43 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo B6E Type2 26 - 317 0 None None Serine/threonine-protein kinase 10
STE STK10 STK10_HUMAN 6EIMB 1.43 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo B6E Type2 23 - 317 0 None None Serine/threonine-protein kinase 10
TKL BRAF BRAF_HUMAN 4H58C 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9RB 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type1 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CSXA 2.51 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 54J Type1.5_Back 448 - 720 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7YA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7YB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno TXV Type2 449 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V34A 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnoo QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6V34B 3.15 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4R5YA 3.5 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4R5YB 3.5 Inactive DFGout‑BBAminus in-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XFPA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo V1Y Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XLOA 2.493 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo V5J Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6XLOB 2.493 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn V5J Type2 450 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VA 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VB 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VC 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno VQP Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 7K0VD 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P3DA 2.11 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnoo 0LI Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GA 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GC 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GD 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7OA 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iioo QOP Type2 449 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7OB 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo QOP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7PA 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8F7PB 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nioo K81 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGA 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGB 3.09 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGC 3.09 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4JVGD 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6CADA 2.55 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno EU4 Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6NSQA 3.05 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo KZP Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7XA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8C7XB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo TXV Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV9A 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nioo 1OO Type2 448 - 705 0 None R443S,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HI2A 2.512 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn BAX Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIDA 2.5 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIDB 2.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWJA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWJB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0PA 2.37 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0PB 2.37 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8QQGB 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 8QQGC 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5CT7A 3.17 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 55J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VALA 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 92D Type2 446 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VALB 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 92D Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VAMA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5VAMB 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6B8UA 2.68 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 8EN Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6B8UB 2.68 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 8EN Type2 447 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0QA 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno K7S Type2 446 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6N0QB 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno K7S Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3Q96A 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 0NF Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3Q96B 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0NF Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNA 3.15 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4DBNB 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FC0A 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4FC0B 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSPA 2.93 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSPB 2.93 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSQA 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SW Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4KSQB 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SW Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3IDPA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3IDPB 2.7 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9RA 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno B1E Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5C9CA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5C9CB 2.7 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWHA 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 1UWHB 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3II5A 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 831 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 3II5B 2.79 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 831 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9CA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nooo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4G9CB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 6P7GB 2.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo E7M, NHE Type2, Allosteric 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf
TKL LIMK1 LIMK1_HUMAN 7B8WA 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 633 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WB 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WC 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7B8WD 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 331 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1
TKL LIMK1 LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1
TKL LIMK2 LIMK2_HUMAN 7QHGA 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_oooo T3B Type2 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 7QHGB 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoao APEdist_iooo T3B Type2 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 631 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 632 0 None None LIM domain kinase 2
TKL LIMK2 LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2
TKL LRRK2 LRRK2_HUMAN 8TZBA 3.1 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U7LA 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U7LB 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8AB 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8AC 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8BA 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8U8BB 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2
TKL LRRK2 LRRK2_HUMAN 8TYQA 2.99 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1335 - 2525 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2
TKL MAP3K7 M3K7_HUMAN 5E7RA 2.11 Inactive DFGout‑BBAminus none-none none-out nonTYR APEdihe_aaooi APEdist_nnno 5KW Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 2YIYA 2.49 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno YIY Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 4O91A 2.393 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno NG2 Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL MAP3K7 M3K7_HUMAN 5GJDA 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno 6V3 Type2 31 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7
TKL RIPK1 RIPK1_HUMAN 9Q31B 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno TME, A1CNU Allosteric, Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZZA 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU5 Type1 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C3EB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type1 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7XMKA 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno GO4 Type1 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7XMKB 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn GO4 Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7YDXB 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 8I2NA 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5HX6B 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 65U Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5TX5B 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 7MJ Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6OCQA 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6RLNB 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn K8K Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTGB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IPG, RCM Type1, Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1HX Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITJB 1.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 1HX Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7YDXA 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 8I2NB 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FD0A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 3IU Type2 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FD0B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 3IU Type2 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4NEUA 2.57 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aaiii APEdist_nnni Q1A Type2 6 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4NEUB 2.57 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn Q1A Type2 7 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZYA 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZYB 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZZB 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU5 Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZXA 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9MZXB 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C3EA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type3 9 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITHB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITIA 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo 1HW Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 4ITIB 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1HW Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NYHA 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NYHB 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q31A 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNU Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32A 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32B 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32C 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9Q32D 2.49 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FCZA 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 3IF Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 7FCZB 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3IF Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8A 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX7 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY9A 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX9 Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9HY9B 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1IX9 Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DA 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DB 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DC 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6C4DD 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno EJP Type3 5 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5HX6A 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 65U Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 5TX5A 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 7MJ Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6HHOA 3.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno G4W Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6HHOB 3.49 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn G4W Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6OCQB 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FA 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FB 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FC 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6R5FD 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6RLNA 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno K8K Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NW2A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn L4Y Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 6NW2B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno L4Y Type3 11 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYA 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTGA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IPG Type3, Type1 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK1 RIPK1_HUMAN 9GTYB 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IKX Type3, Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1
TKL RIPK2 RIPK2_HUMAN 6ES0A 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno BW8 Type2 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 6ES0B 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BW8 Type2 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL RIPK2 RIPK2_HUMAN 5AR7B 2.71 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2
TKL TNNI3K TNI3K_HUMAN 7MGKA 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKB 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKC 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZGD Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGKD 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJA 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJB 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJC 2.95 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TKL TNNI3K TNI3K_HUMAN 7MGJD 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K
TYR ABL1 ABL1_HUMAN 6XRGA 999.0 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None G250E,M290L,T389Y Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRJA 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 234 - 496 0 None T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRJB 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 233 - 497 0 None T315I Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ0A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GIN Type2 233 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HZ0B 2.1 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan GIN Type2 228 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 235 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYC 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HYYD 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9A 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9B 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9C 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 232 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3CS9D 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRIA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRIB 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 232 - 498 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HIWA 2.2 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2HIWB 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2E2BA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2E2BB 2.2 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 497 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 5HU9A 1.529 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 66K, 66K Type2, Allosteric 229 - 499 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3PYYA 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, 3YY Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3PYYB 1.85 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao STI, 3YY Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPEA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWD Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPEB 2.15 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai STI, KWD Type2, Allosteric 233 - 511 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPUA 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPUB 2.33 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPVA 1.86 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 6NPVB 1.86 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 3QRKA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1
TYR ABL2 ABL2_HUMAN 3GVUA 2.05 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai STI, STI Type2, Allosteric 279 - 546 0 None None Tyrosine-protein kinase ABL2
TYR ALK ALK_HUMAN 5IUGA 1.93 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao 729 Type2 1093 - 1404 0 None C1097S ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 5IUHA 2.1 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao 34Y Type2 1093 - 1404 0 None C1097S ALK tyrosine kinase receptor
TYR CSF1R CSF1R_HUMAN 8CGCA 1.925 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai LMR, UIK Allosteric, Type1 547 - 919 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3BEAA 2.02 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai IXH Type1 547 - 921 0 None A933L Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I1MA 1.8 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 5CN Type1 547 - 921 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 8JOTA 1.69 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai UKI Type1 543 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 8W1LA 2.26 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1AE3 Type1 563 - 914 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I0VA 2.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 6C3 Type1 544 - 916 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 2I0YA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5CN Type1 548 - 916 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3KRJA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai KRJ Type1 544 - 914 0 None S686S Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3KRLA 2.4 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai KRL Type1 545 - 912 0 None S686S Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 7TNHA 2.7 Inactive DFGout‑BBAminus in-none out-in TYR APEdihe_iiiai APEdist_aaai I9W Type1 445 - 912 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6T2WA 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai M9T Type1 547 - 916 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3DPKA 1.95 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai 8C5 Type1.5_Back 548 - 912 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 4HW7A 2.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 64M Type2 566 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 4R7HA 2.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P31 Type2 544 - 915 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 4R7IA 2.75 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 567 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6N33A 2.25 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 622 Type2 566 - 915 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 7MFCA 2.8 Inactive DFGout‑BBAminus in-none out-in TYR APEdihe_iiiai APEdist_aaai Z6V Type2 567 - 913 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6WXJA 2.62 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_nniai APEdist_aaai UF4 Type2 559 - 917 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 3LCOA 3.4 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai LC0 Type2 551 - 915 0 None None Macrophage colony-stimulating factor 1 receptor
TYR CSF1R CSF1R_HUMAN 6IG8A 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A7O Type2 550 - 916 0 None S688A Macrophage colony-stimulating factor 1 receptor
TYR DDR1 DDR1_HUMAN 5SAUA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IF Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAVA 1.76 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAWA 1.601 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 603 - 907 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAXA 1.902 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAYA 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 907 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAYB 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SAZA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IW Type2 603 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SB0A 1.97 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IZ Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5SB1A 1.53 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1JI Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FEWA 1.44 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FEXA 1.291 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Z Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FILA 1.73 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FINA 1.67 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJQ Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FIOA 1.99 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJH Type2 598 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6FIQA 1.79 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai DJW Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 3ZOSB 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 4BKJA 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 4BKJB 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 4CKRA 2.2 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai DI1 Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6GWRA 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6GWRB 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6HP9A 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 601 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 6HP9B 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 603 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BCMA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BCMB 2.3 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7BE6A 1.871 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TJW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVNA 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5BVOA 1.98 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VE Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5FDPA 2.25 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5WR Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5FDXA 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 5FDXB 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 605 - 907 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 3ZOSA 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI, 0LI Type2, Allosteric 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR1 DDR1_HUMAN 7FEHA 1.61 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1
TYR DDR2 DDR2_HUMAN 6FERD 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERI 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 555 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERA 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERB 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERC 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERE 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERF 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERG 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERH 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERJ 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERK 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 555 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 6FERL 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 554 - 851 0 None None Discoidin domain-containing receptor 2
TYR DDR2 DDR2_HUMAN 7AYMA 2.12 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 558 - 849 0 None K826E,L847R Discoidin domain-containing receptor 2
TYR EGFR EGFR_HUMAN 2RF9A 3.5 Inactive DFGout‑BBAminus out-none in-out TYR APEdihe_ooiai APEdist_aaai No_ligand No_ligand 699 - 983 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZJVA 2.7 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 703 - 985 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 4ZJVB 2.7 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 703 - 982 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG5A 1.52 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 633 Type1 700 - 1001 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG7A 1.85 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 630 Type1 702 - 984 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG8A 1.42 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 634 Type1 700 - 999 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5HG9A 2.15 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 63A Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5U8LA 1.6 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai O44 Type1 702 - 990 0 None None Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UG8A 1.46 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BP Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UG9A 1.33 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UGAA 1.82 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BM Type1 703 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 5UGCA 1.58 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor
TYR EPHA2 EPHA2_HUMAN 8XPVA 1.55 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 4Z5 Type2 604 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNFA 1.556 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan DXH Type2 606 - 894 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6FNGA 1.038 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_niiai APEdist_aaai DWT Type2 599 - 897 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HESA 1.128 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G0H Type2 599 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HETA 1.208 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G0Q Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEUA 1.719 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G0N Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEVA 1.28 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai G0K Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEWA 1.268 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao G0E Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEXA 1.413 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G02 Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6HEYA 1.367 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_niiai APEdist_aaao FZW Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7BA 1.009 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao HO5 Type2 599 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7CA 1.049 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao HOK Type2 599 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7DA 0.978 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao HOT Type2 600 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7EA 1.059 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan HMW Type2 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 6Q7GA 1.047 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan HO8 Type2 601 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BM8A 1.68 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao QT1 Type2 605 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOCA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai QUF Type2 605 - 888 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BODA 1.5 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan QTX Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOGA 1.47 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan QUU Type2 600 - 895 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOHA 1.42 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao R0T Type2 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOIA 1.63 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao R0O Type2 604 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOKA 2.02 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai R0X Type2 605 - 890 0 None None Ephrin type-A receptor 2
TYR EPHA2 EPHA2_HUMAN 8BOMA 1.12 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan QU6 Type2 605 - 896 0 None None Ephrin type-A receptor 2
TYR EPHA3 EPHA3_HUMAN 3DZQA 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan IFC Type2 609 - 904 0 None None Ephrin type-A receptor 3
TYR EPHA7 EPHA7_HUMAN 3DKOA 2.0 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan IHZ Type2 607 - 899 0 None None Ephrin type-A receptor 7
TYR EPHB4 EPHB4_HUMAN 6FNIA 1.468 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_nniai APEdist_aaao DXH Type2 607 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNJA 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR EPHB4 EPHB4_HUMAN 6FNJB 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4
TYR FGFR1 FGFR1_HUMAN 4V04B 2.12 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4UXQA 1.85 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 452 - 750 0 None C477A Fibroblast growth factor receptor 4
TYR FGFR4 FGFR4_HUMAN 4TYJA 2.45 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 447 - 753 0 None None Fibroblast growth factor receptor 4
TYR FLT1 VGFR1_HUMAN 3HNGA 2.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ST Type2 803 - 1158 0 None None Vascular endothelial growth factor receptor 1
TYR FLT3 FLT3_HUMAN 4XUFA 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4XUFB 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR FLT3 FLT3_HUMAN 4RT7A 3.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3
TYR IGF1R IGF1R_HUMAN 3LW0A 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0B 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3LW0C 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor
TYR INSR INSR_HUMAN 1IRKA 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1008 - 1310 0 None None Insulin receptor
TYR INSR INSR_HUMAN 3ETAA 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 351 Type2 1017 - 1310 0 None None Insulin receptor
TYR INSR INSR_HUMAN 3ETAB 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 351 Type2 1017 - 1310 0 None None Insulin receptor
TYR JAK2-2 JAK2_HUMAN 7RN6A 1.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioai APEdist_aaao 046 Type2 839 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3UGCA 1.34 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oioai APEdist_aaao 046 Type2 843 - 1129 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 7TEUA 1.45 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oioai APEdist_aaao I6C Type2 843 - 1131 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2
TYR KDR VGFR2_HUMAN 4AG8A 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4AGDA 2.81 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 802 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPBB 2.7 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C92 Type1 820 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2XIRA 1.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 00J Type1.5_Back 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4AGCA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1.5_Back 801 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3WZEA 1.9 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao BAX Type2 815 - 1167 0 None T940V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2OH4A 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iioai APEdist_aaao GIG Type2 816 - 1171 0 PTR1054,PTR1059 None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2P2IA 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 608 Type2 817 - 1172 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3EFLA 2.2 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 706 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3EFLB 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 706 Type2 821 - 1165 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 5EW3A 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 5T2 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 5EW3B 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 5T2 Type2 820 - 1165 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6GQOA 1.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F82 Type2 811 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6GQPA 2.09 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6GQQA 1.52 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F8B Type2 813 - 1167 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6XVJA 1.78 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O35 Type2 813 - 1167 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 6XVKA 1.99 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O3E Type2 821 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4ASDA 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai BAX Type2 807 - 1168 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 4ASEA 1.83 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AV9 Type2 807 - 1169 0 None E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VHEA 1.55 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao 42Q Type2 811 - 1169 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3VHKA 2.49 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao BPK Type2 814 - 1168 0 None None Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2QU5A 2.95 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oooai APEdist_aaao 276 Type2 816 - 1170 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2QU6A 2.1 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 857 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 2RL5A 2.65 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oooai APEdist_aaao 2RL Type2 815 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3B8QB 2.75 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 900 Type2 820 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3BE2A 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan RAJ Type2 815 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CP9A 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C19 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CP9B 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C19 Type2 819 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3CPCB 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C52 Type2 820 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3DTWB 2.9 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nooai APEdist_aaao A96 Type2 820 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3EWHA 1.6 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_nniai APEdist_aaai K11 Type2 815 - 1171 0 None C817A,V916T,E990V Vascular endothelial growth factor receptor 2
TYR KDR VGFR2_HUMAN 3U6JA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 03X Type2 815 - 1171 0 None V916T,E990V Vascular endothelial growth factor receptor 2
TYR KIT KIT_HUMAN 8S13A 2.0 Inactive DFGout‑BBAminus in-none out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S14A 1.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 554 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S15A 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XIN Type1 554 - 929 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 3G0FA 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 566 - 930 0 None D816H Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 3G0FB 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 564 - 930 0 None D816H Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7ZW8A 2.119 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R Type1 554 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6KLAA 2.109 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJX Type1 554 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 4HVSA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 647 Type2 551 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,I690H,C691S,K693D,Q694T,E695S,I756S,L762N,V825D,C844S,L890S,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7KHGA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P31 Type2 547 - 931 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S16A 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S16B 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S17A 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S17B 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S18A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1H4U Type2 568 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S18B 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1H4U Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQJA 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F82 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQJB 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F82 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQKA 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQKB 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQLA 2.01 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F8B Type2 568 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQLB 2.01 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F8B Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQMA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F8H Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6GQMB 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F8H Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XV9A 3.38 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O35 Type2 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XV9B 3.38 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O35 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVAA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2K Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVAB 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2K Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVBA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2H Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6XVBB 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2H Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6HH1A 2.25 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_iiiai APEdist_aaan G4E Type2 565 - 929 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6MOBA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai JWY Type2 567 - 930 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 1T46A 1.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 565 - 933 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 4U0IA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 565 - 933 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 7ZY6A 3.09 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai KCI Type2 557 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6ITTA 2.103 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AWO Type2 563 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6ITTB 2.103 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AWO Type2 566 - 932 0 None None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 6ITVA 1.881 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AWO Type2 569 - 935 0 PTR570 None Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1BB 2.0 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R, K3R, K3R Type2, Allosteric, Allosteric 565 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit
TYR LCK LCK_HUMAN 6PDJA 1.81 Inactive DFGout‑BBAminus out-none in-in TYR APEdihe_iiiai APEdist_aaai ODJ Type1.5_Front 225 - 500 0 PTR394 None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OG8A 2.3 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 1N8 Type2 237 - 499 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2OG8B 2.3 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 1N8 Type2 237 - 499 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3BYSA 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnnao APEdist_aaan AM5 Type2 230 - 501 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 3BYUA 2.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioao APEdist_aaai AM6 Type2 231 - 501 0 None None Tyrosine-protein kinase Lck
TYR LCK LCK_HUMAN 2PL0A 2.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 231 - 498 0 None None Tyrosine-protein kinase Lck
TYR LMTK3 LMTK3_HUMAN 6SEQA 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 130 - 413 0 None None Serine/threonine-protein kinase LMTK3
TYR MERTK MERTK_HUMAN 9KS9B 2.8 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6L Type1 577 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7XHYA 2.16 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan E0X Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AAYA 1.87 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 9KRYB 2.25 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW4A 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer
TYR MERTK MERTK_HUMAN 7AW4B 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer
TYR MET MET_HUMAN 3RHKB 1.94 Inactive DFGout‑BBAminus out-none out-in TYR APEdihe_iiiai APEdist_aaai M97 Type1 1046 - 1344 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8ANSA 2.01 Inactive DFGout‑BBAminus out-none in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8VI1A 3.11 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao A1AB1 Type1.5_Front 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8VI1B 3.11 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai A1AB1 Type1.5_Front 1050 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AN8A 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nnnai APEdist_aaan MDI Type1.5_Front 1073 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8AN8B 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1058 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SDCA 1.67 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 88Z Type2 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SDDA 1.93 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai 353 Type2 1062 - 1344 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 9C1RA 1.59 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan A1ATS Type2 1048 - 1348 0 None D1228N Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3LQ8A 2.02 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 88Z Type2 1053 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 6SD9A 2.35 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 88Z Type2 1062 - 1345 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4EEVA 1.8 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_niiai APEdist_aaai L1X Type2 1045 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 4MXCA 1.632 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DWF Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 5HTIA 1.66 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 66L Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 7V3SA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5I9 Type2 1053 - 1346 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3VW8A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DF6 Type2 1024 - 1352 0 None None Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CE3A 2.4 Inactive DFGout‑BBAminus out-out none-out TYR APEdihe_oiiai APEdist_aaai 1FN Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3CTHA 2.3 Inactive DFGout‑BBAminus out-out none-out TYR APEdihe_oiiai APEdist_aaai 319 Type2 1052 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3F82A 2.5 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_niiai APEdist_aaai 353 Type2 1055 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 3L8VA 2.4 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_oiiai APEdist_aaai L8V Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUA 1.77 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai W49 Type3 1059 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUUB 1.77 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W49 Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUVA 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1053 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OUVB 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OV7A 1.95 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iioai APEdist_aaao W3W Type3 1051 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OVZA 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1061 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OVZB 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGA 2.631 Inactive DFGout‑BBAminus out-none out-none TYR APEdihe_nnnai APEdist_aaan W40 Type3 1060 - 1344 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGB 2.631 Inactive DFGout‑BBAminus out-none out-in TYR APEdihe_iiiai APEdist_aaai W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OWGC 2.631 Inactive DFGout‑BBAminus out-none none-out TYR APEdihe_nniai APEdist_aaao W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor
TYR MET MET_HUMAN 8OW3A 2.27 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nniai APEdist_aaai W40 Type3 1058 - 1345 0 None None Hepatocyte growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKGA 2.53 Inactive DFGout‑BBAminus in-out none-in TYR APEdihe_iiiai APEdist_aaai 22L, GO7 Allosteric, Type2 500 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKIA 2.11 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 22L, GOD Allosteric, Type2 500 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6D1ZA 1.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai FQD, FQM Allosteric, Type3 483 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7VKMA 2.55 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 502 - 795 0 None G595R High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4PMPA 1.8 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 31W Type1 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5H3QA 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7HF Type1 484 - 796 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 4PMMA 2.0 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 31V Type2 501 - 787 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFSA 2.07 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 6K0 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFVA 1.59 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nniai APEdist_aaai 6K1 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFWA 1.52 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nniai APEdist_aaai 6K2 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 5JFXA 1.63 Inactive DFGout‑BBAminus out-in none-none TYR APEdihe_nniai APEdist_aaai 6K4 Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKWA 2.91 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nniai APEdist_aaai GXA Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6DKWB 2.91 Inactive DFGout‑BBAminus in-out none-in TYR APEdihe_iiiai APEdist_aaai GXA Type2 502 - 793 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL2A 2.59 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai OOM Type2 499 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 7XBIA 2.16 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CVY Type2 497 - 795 0 None None High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 8J5XA 2.092 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A4U Type2 500 - 795 0 None G595R High affinity nerve growth factor receptor
TYR NTRK1 NTRK1_HUMAN 6PL4A 2.06 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai OO7 Type3 485 - 795 0 SEP677 None High affinity nerve growth factor receptor
TYR NTRK2 NTRK2_HUMAN 4AT4A 2.36 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai T6E Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor
TYR NTRK3 NTRK3_HUMAN 3V5QA 2.2 Inactive DFGout‑BBAminus out-out none-in TYR APEdihe_iiiai APEdist_aaai 0F4 Type2 530 - 832 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 3V5QB 2.2 Inactive DFGout‑BBAminus out-out none-in TYR APEdihe_iiiai APEdist_aaai 0F4 Type2 530 - 832 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 6KZCA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DZC Type2 528 - 837 0 None None NT-3 growth factor receptor
TYR NTRK3 NTRK3_HUMAN 6KZDA 1.708 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DZ6 Type2 528 - 837 0 None None NT-3 growth factor receptor
TYR PDGFRA PGFRA_HUMAN 9GZHA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1IRC Type2 583 - 958 0 None T674I Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 5GRNA 1.77 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 748 Type2 583 - 958 0 None None Platelet-derived growth factor receptor alpha
TYR PDGFRA PGFRA_HUMAN 6JOLA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 583 - 957 0 None None Platelet-derived growth factor receptor alpha
TYR PTK2 FAK1_HUMAN 4KAOA 2.39 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 415 - 686 0 None P410G Focal adhesion kinase 1
TYR PTK2 FAK1_HUMAN 4KAOB 2.39 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 414 - 686 0 None P410G Focal adhesion kinase 1
TYR PTK2B FAK2_HUMAN 3FZSA 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai B96 Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK2B FAK2_HUMAN 4H1MA 1.99 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 0YJ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta
TYR PTK6 PTK6_HUMAN 6CZ4A 1.5 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan FKY Type2 183 - 443 0 None None Protein-tyrosine kinase 6
TYR PTK7 PTK7_HUMAN 6VG3A 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1064 0 None None Inactive tyrosine-protein kinase 7
TYR PTK7 PTK7_HUMAN 6VG3B 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1066 0 None None Inactive tyrosine-protein kinase 7
TYR PTK7 PTK7_HUMAN 6VG3C 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 789 - 1063 0 None None Inactive tyrosine-protein kinase 7
TYR SRC SRC_HUMAN 7OTEA 2.49 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SRC SRC_HUMAN 7OTEB 2.49 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src
TYR SYK KSYK_HUMAN 3TUBA 2.23 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan FPU Type2 362 - 633 0 None None Tyrosine-protein kinase SYK
TYR TEK TIE2_HUMAN 2OO8X 2.2 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_iiiai APEdist_aaao RAJ Type2 836 - 1117 0 None None Angiopoietin-1 receptor
TYR TEK TIE2_HUMAN 2OSCA 2.8 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao MUH Type2 837 - 1116 0 None None Angiopoietin-1 receptor
TYR TEK TIE2_HUMAN 2P4IA 2.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai MR9 Type2 838 - 1117 0 None None Angiopoietin-1 receptor
TYR TEK TIE2_HUMAN 6MWEA 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor
TYR TEK TIE2_HUMAN 6MWEB 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor

All / BBAminus / All

Total number of chains: 682
Active chains: 0
Total number of genes: 70
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 682 100.0% 3KFAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 7D57A 2.104 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan 37O Type1 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3WA 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1BU Type2 257 - 533 0 None T338M,S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3WB 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1BU Type2 258 - 533 0 None T338M,S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G6HB 2.35 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan G6H Type2 258 - 533 0 None T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3OEZA 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao STI Type2 257 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3OEZB 2.4 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nnoai APEdist_aaao STI Type2 256 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 2OIQA 2.07 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao STI Type2 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G6GA 2.31 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao G6G Type2 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBJA 2.61 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 4A9 Type2 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBJB 2.61 Inactive DFGout‑BBAminus in-none none-out TYR APEdihe_nniai APEdist_aaao 4A9 Type2 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7WF5A 1.798 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7WF5B 1.798 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 254 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3VA 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 1BU Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3VB 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1BU Type2 256 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ7A 3.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao AQB Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ7B 3.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao AQB Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ8A 2.7 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao AQM Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ8B 2.7 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioai APEdist_aaao AQM Type2 256 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ9A 3.1 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao AQU Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5SYSA 2.8 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 72F Type2 258 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5SYSB 2.8 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 72F Type2 258 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3UB 2.5 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nniai APEdist_aaai 1AW Type3 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3TA 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1AU, 1AU Type3, Type1 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3UA 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1AW, 1AW Type3, Type1 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
AGC AKT1 AKT1_HUMAN 8UVYA 2.11 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaiii APEdist_iiio XOO Allosteric 3 - 439 0 None E17K RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 8UW2A 2.2 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaioi APEdist_oooo XOO Allosteric 4 - 437 0 None None RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 8UW9A 1.9 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaiii APEdist_iiio XQ2 Allosteric 3 - 428 0 None None RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 8UW7A 1.972 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno XOO Allosteric 3 - 439 0 None None RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 3O96A 2.7 Inactive DFGout‑BBAminus none-none out-none nonTYR APEdihe_aannn APEdist_nnnn IQO Allosteric 2 - 429 0 None None RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 6HHHA 2.7 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaooi APEdist_nnno G4Q Allosteric 2 - 439 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 6HHJA 2.3 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo G4H Allosteric 3 - 444 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 6S9WA 2.3 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo L1Z Allosteric 3 - 444 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT1 AKT1_HUMAN 4EJNA 2.19 Inactive DFGout‑BBAminus none-none out-out nonTYR APEdihe_aaiii APEdist_oioo 0R4 Type1 4 - 438 0 None E114A,E115A,E116A RAC-alpha serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 9C1WA 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno XOO Allosteric 3 - 440 0 None P115A,G116A RAC-beta serine/threonine-protein kinase Homo sapiens
AGC AKT2 AKT2_HUMAN 8Q61A 2.32 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn K06 Type3 1 - 435 0 None N2D RAC-beta serine/threonine-protein kinase Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3NAXA 1.75 Inactive DFGout‑BBAminus out-out in-none nonTYR APEdihe_aannn APEdist_nnnn MP7 Type2 76 - 360 0 None None 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC PDPK1 PDPK1_HUMAN 3QC4A 1.8 Inactive DFGout‑BBAminus out-out in-in nonTYR APEdihe_aaiii APEdist_iiii MP7 Type2 76 - 359 0 SEP241 E303A,K304A 3-phosphoinositide-dependent protein kinase 1 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 9JCUA 3.02 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiio No_ligand No_ligand 27 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 9JCUC 3.02 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaioi APEdist_iiii No_ligand No_ligand 27 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8GDSA 2.71 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_nooo Z8O Type1 24 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8GDSB 2.71 Inactive DFGout‑BBAminus out-none in-out nonTYR APEdihe_aaiii APEdist_nooo Z8O Type1 24 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8GDSC 2.71 Inactive DFGout‑BBAminus out-none in-out nonTYR APEdihe_aaioi APEdist_nnno Z8O Type1 24 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
AGC ROCK2 ROCK2_HUMAN 8GDSD 2.71 Inactive DFGout‑BBAminus out-none in-none nonTYR APEdihe_aaiii APEdist_nnii Z8O Type1.5_Front 24 - 417 0 None None Rho-associated protein kinase 2 Homo sapiens
CAMK AURKA AURKA_HUMAN 2C6EA 2.1 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno HPM Type1.5_Back 127 - 389 0 None None Aurora kinase A Homo sapiens
CAMK MKNK1 MKNK1_HUMAN 2HW6A 2.5 Inactive DFGout‑BBAminus in-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 39 - 376 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
CAMK MKNK1 MKNK1_HUMAN 2HW6B 2.5 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 40 - 375 0 None None MAP kinase-interacting serine/threonine-protein kinase 1 Homo sapiens
CAMK MKNK2 MKNK2_HUMAN 2AC3A 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo No_ligand No_ligand 72 - 369 0 None None MAP kinase-interacting serine/threonine-protein kinase 2 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 2H6DA 1.85 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None None 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
CAMK PRKAA2 AAPK2_HUMAN 2YZAA 3.02 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 10 - 278 0 None T172D 5'-AMP-activated protein kinase catalytic subunit alpha-2 Homo sapiens
CK1 CSNK1E KC1E_HUMAN 4HNIA 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 3 - 293 0 None None Casein kinase I isoform epsilon Homo sapiens
CK1 CSNK1E KC1E_HUMAN 4HNIB 2.74 Inactive DFGout‑BBAminus in-none in-in nonTYR APEdihe_aaiii APEdist_iiii 16W Type1 1 - 293 0 None None Casein kinase I isoform epsilon Homo sapiens
CMGC CDK16 CDK16_HUMAN 5G6VA 2.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo 919 Type2 163 - 474 0 None S319D Cyclin-dependent kinase 16 Homo sapiens
CMGC CDK6 CDK6_HUMAN 1G3NA 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK6 CDK6_HUMAN 1G3NE 2.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_oooo No_ligand No_ligand 9 - 301 0 None None Cyclin-dependent kinase 6 Homo sapiens
CMGC CDK8 CDK8_HUMAN 3RGFA 2.2 Inactive DFGout‑BBAminus in-out out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 1 - 353 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F6UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnio 0SR Type2 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F6WA 2.39 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 0SS Type2 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F7LA 2.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 0SO Type2 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F7NA 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnio 0SV Type2 1 - 361 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 5HVYA 2.39 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oioo 66X Type2 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 6TPAA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn NZ8, NZ5, NZ5, NZ5 Type2, Allosteric, Allosteric, Allosteric 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F6SA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0SQ Type3 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC CDK8 CDK8_HUMAN 4F7JA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0SU Type3 1 - 359 0 None None Cyclin-dependent kinase 8 Homo sapiens
CMGC MAPK11 MK11_HUMAN 3GP0A 1.9 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno NIL Type2 5 - 348 0 None None Mitogen-activated protein kinase 11 Homo sapiens
CMGC MAPK13 MK13_HUMAN 4EYJA 2.102 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno N61 Type2 2 - 351 0 None None Mitogen-activated protein kinase 13 Homo sapiens
CMGC MAPK14 MK14_HUMAN 9CJ3A 1.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo PDO, A1AWV Allosteric, Type2 4 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6QDZA 1.73 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno I46, HYK Allosteric, Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6QE1A 1.85 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno I46, HYW Allosteric, Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GCQA 2.0 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno 1BU Type2 4 - 355 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GCSA 2.1 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aanii APEdist_nnnn BAX Type2 5 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GCVA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo SS6 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV3A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno R49 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFEA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z84 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFFA 1.5 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z83 Type2 5 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3PG3A 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaooi APEdist_nnno DG7 Type2 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6SFIA 1.6 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno LB5 Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6SFJA 1.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo LBB Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6SFOA 1.75 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno LBE Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 6ZWPA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno OE8 Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3CTQA 1.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno 337 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 5MZ3A 2.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 8EN Type2 4 - 353 0 None C162S Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HEGA 2.2 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BAX Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1W83A 2.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L11 Type2 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1WBNA 2.4 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L09 Type2 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3D83A 1.9 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo GK6 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 9CJ4A 1.8 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo B96 Type2 5 - 352 0 TPO180,PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GCUA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R48 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GCUB 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R48 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV4A 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo L51 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV4B 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo L51 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV5A 2.25 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R24 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV5B 2.25 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo R24 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV6A 1.95 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno R39 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2BAKA 2.2 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno AQZ Type2 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4A9YA 2.2 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno AQZ Type2 5 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 4AA0A 1.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno AA0 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3E93A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_oooo 19B Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3KQ7A 1.8 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo KQ7 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3GI3A 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno B10 Type2 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3IW8A 2.0 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno HIZ Type3 4 - 352 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFBA 2.6 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z87 Type3 4 - 353 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3LFCA 2.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno Z86 Type3 4 - 354 0 None C119S,C162S,A172C,F327L Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NNVA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo 437 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3NNXA 2.28 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nioo EDD Type3 5 - 352 0 PTR182 None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1W82A 2.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo L10 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 1WBVA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo LI3 Type3 4 - 355 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3HV7A 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo 1AU Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 2BAJA 2.25 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iooo 1PP Type3 2 - 353 0 None None Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3O8UA 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno BMU Type3 5 - 352 0 None F169Y Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3OBJA 2.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno BMU Type3 5 - 352 0 None F169R Mitogen-activated protein kinase 14 Homo sapiens
CMGC MAPK14 MK14_HUMAN 3K3IA 1.7 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno JZJ, I46, I46 Type3, Allosteric, Allosteric 5 - 352 0 None None Mitogen-activated protein kinase 14 Homo sapiens
NEK NEK7 NEK7_HUMAN 8WS0B 2.12 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 19 - 299 0 None S195D Serine/threonine-protein kinase Nek7 Homo sapiens
NEK NEK7 NEK7_HUMAN 8WS1B 2.4 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanno APEdist_nnnn No_ligand No_ligand 20 - 300 0 None D161N Serine/threonine-protein kinase Nek7 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7JA 2.3 Inactive DFGout‑BBAminus out-out none-none nonTYR APEdihe_aannn APEdist_nnnn 3Z1 Type1 585 - 1086 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7KA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z3 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7LA 1.9 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z4 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER EIF2AK3 E2AK3_HUMAN 4X7NA 2.35 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 3Z5 Type2 585 - 1087 0 None D937N Eukaryotic translation initiation factor 2-alpha kinase 3 Homo sapiens
OTHER ULK3 ULK3_HUMAN 6FDZU 2.55 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_iooo C87 Type1 8 - 274 0 None None Serine/threonine-protein kinase ULK3 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6YG7A 2.2 Inactive DFGout‑BBAminus na-na none-out nonTYR APEdihe_aanao APEdist_nnnn OQ2 Type2 102 - 403 0 None S271D,T275D Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP2K7 MP2K7_HUMAN 6YG7B 2.2 Inactive DFGout‑BBAminus na-na none-out nonTYR APEdihe_aaiao APEdist_nnno OQ2 Type2 103 - 403 0 None S271D,T275D Dual specificity mitogen-activated protein kinase kinase 7 Homo sapiens
STE MAP3K2 M3K2_HUMAN 9P6AA 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo 0LI Type2 351 - 617 0 None None Mitogen-activated protein kinase kinase kinase 2 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0KA 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0KB 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 8 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0KC 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 8 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0KD 2.01 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK7 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0LA 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0LB 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 7 - 291 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0LC 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 5 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 7M0LD 2.43 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo YK4 Type1 6 - 294 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 8XN7A 2.65 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo A1LVT Type1 6 - 292 0 None T165E,S171E Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 8XN7B 2.65 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo A1LVT Type1 6 - 293 0 None T165E,S171E Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 6NG0B 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo B49 Type1 7 - 293 0 None T165E,S171E Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 9BIKA 2.25 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_oooo A1APO Type1 6 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K1 M4K1_HUMAN 9N7RB 2.13 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo A1BWC Type1 8 - 293 0 None None Mitogen-activated protein kinase kinase kinase kinase 1 Homo sapiens
STE MAP4K4 M4K4_HUMAN 4U3YB 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_oooo No_ligand No_ligand 8 - 311 0 None None Mitogen-activated protein kinase kinase kinase kinase 4 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJIA 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJIB 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OQ Type3 254 - 540 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJIC 1.99 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 250 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJID 1.99 Inactive DFGout‑BBAminus out-out in-out nonTYR APEdihe_aaiii APEdist_oooo 4OQ Type3 253 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJA 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 249 - 539 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJB 2.2 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_iioi 4OR Type3 251 - 539 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJC 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_nnno 4OR Type3 251 - 542 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK1 PAK1_HUMAN 4ZJJD 2.2 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaiii APEdist_oooo 4OR Type3 252 - 541 0 None None Serine/threonine-protein kinase PAK 1 Homo sapiens
STE PAK2 PAK2_HUMAN 9M41A 3.02 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaiio APEdist_oooo No_ligand No_ligand 85 - 520 0 None K278R,D368N Serine/threonine-protein kinase PAK 2 Homo sapiens
STE SLK SLK_HUMAN 8BEMD 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE SLK SLK_HUMAN 8BEMG 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE SLK SLK_HUMAN 8BEMA 2.6 Inactive DFGout‑BBAminus out-none none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 309 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE SLK SLK_HUMAN 8BEMB 2.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno AV9 Type1.5_Front 19 - 310 0 None None STE20-like serine/threonine-protein kinase Homo sapiens
STE STK10 STK10_HUMAN 6GTTA 2.25 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanio APEdist_nnnn B96 Type2 18 - 316 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STE STK10 STK10_HUMAN 6EIMA 1.43 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo B6E Type2 26 - 317 0 None None Serine/threonine-protein kinase 10 Homo sapiens
STE STK10 STK10_HUMAN 6EIMB 1.43 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo B6E Type2 23 - 317 0 None None Serine/threonine-protein kinase 10 Homo sapiens
TKL BRAF BRAF_HUMAN 4H58C 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_oooo No_ligand No_ligand 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9RB 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno B1E Type1 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CSXA 2.51 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 54J Type1.5_Back 448 - 720 0 None R443P,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7YA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7YB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno TXV Type2 449 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V34A 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnoo QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6V34B 3.15 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aannn APEdist_nnnn QOP Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4R5YA 3.5 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aanoi APEdist_nnnn 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4R5YB 3.5 Inactive DFGout‑BBAminus in-out out-out nonTYR APEdihe_aaoii APEdist_nnoo 3K3 Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XFPA 2.0 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo V1Y Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XLOA 2.493 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo V5J Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6XLOB 2.493 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn V5J Type2 450 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VA 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_iooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VB 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VC 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno VQP Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 7K0VD 1.93 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo VQP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P3DA 2.11 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnoo 0LI Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GA 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 720 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GC 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GD 2.65 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo E7M Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7OA 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_iioo QOP Type2 449 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7OB 3.54 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oooo QOP Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7PA 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8F7PB 2.74 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nioo K81 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGA 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGB 3.09 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGC 3.09 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4JVGD 3.09 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aanii APEdist_nnnn B96 Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6CADA 2.55 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno EU4 Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6NSQA 3.05 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_oooo KZP Type2 448 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7XA 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo TXV Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8C7XB 1.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnoo TXV Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV9A 2.0 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nioo 1OO Type2 448 - 705 0 None R443S,I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HI2A 2.512 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn BAX Type2 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIDA 2.5 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5HIDB 2.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iioo B1E Type2 449 - 722 0 None I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWJA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWJB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BAX Type2 448 - 723 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0PA 2.37 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0PB 2.37 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo K81 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8QQGB 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 8QQGC 2.979 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_oooo WJ9 Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5CT7A 3.17 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 55J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VALA 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aanoi APEdist_nnnn 92D Type2 446 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VALB 2.26 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 92D Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VAMA 2.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_oioo 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5VAMB 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 92J Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6B8UA 2.68 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 8EN Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6B8UB 2.68 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 8EN Type2 447 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0QA 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno K7S Type2 446 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6N0QB 2.04 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno K7S Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3Q96A 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 0NF Type2 449 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3Q96B 3.1 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0NF Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4DBNA 3.15 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4DBNB 3.15 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno 0JA Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FC0A 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4FC0B 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno 0T2 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSPA 2.93 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSPB 2.93 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 1SU Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSQA 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno 1SW Type2 448 - 722 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4KSQB 3.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 1SW Type2 449 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3IDPA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nnno L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3IDPB 2.7 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnoo L1E Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9RA 3.2 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno B1E Type2 448 - 721 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5C9CA 2.7 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aanoi APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 5C9CB 2.7 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanii APEdist_nnnn 4Z5 Type2 449 - 720 0 None V600E Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWHA 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 1UWHB 2.95 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nioo BAX Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3II5A 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 831 Type2 448 - 720 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 3II5B 2.79 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiii APEdist_nnno 831 Type2 449 - 721 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9CA 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nooo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4G9CB 3.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaiii APEdist_nioo 0WP Type2 448 - 723 0 None None Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 6P7GB 2.65 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_iooo E7M, NHE Type2, Allosteric 449 - 721 0 None I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G Serine/threonine-protein kinase B-raf Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WA 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 633 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WB 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WC 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn T3B Type2 330 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7B8WD 2.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanai APEdist_nnnn T3B Type2 331 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUA 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 634 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUB 2.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iioo RXN Type3 330 - 636 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUC 2.8 Inactive DFGout‑BBAminus out-none out-none nonTYR APEdihe_aanai APEdist_nnnn RXN Type3 350 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK1 LIMK1_HUMAN 7ATUD 2.8 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaini APEdist_nnno RXN Type3 354 - 632 0 None None LIM domain kinase 1 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 7QHGA 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_oooo T3B Type2 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 7QHGB 1.45 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoao APEdist_iooo T3B Type2 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 4TPTA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 631 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 4TPTB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiai APEdist_iooi 35H Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LIMK2 LIMK2_HUMAN 5NXDB 1.9 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 9D8 Type3 330 - 632 0 None None LIM domain kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TZBA 3.1 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1334 - 2522 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U7LA 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U7LB 3.6 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaini APEdist_nnno T3X Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8AB 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8AC 3.4 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaiii APEdist_nnno 0LI Type2 558 - 2526 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8BA 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8U8BB 3.7 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaioi APEdist_nnno 919 Type2 558 - 2527 0 None None Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL LRRK2 LRRK2_HUMAN 8TYQA 2.99 Inactive DFGout‑BBAminus in-out none-none nonTYR APEdihe_aannn APEdist_nnnn T3X Type2 1335 - 2525 0 None G2019S Leucine-rich repeat serine/threonine-protein kinase 2 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5E7RA 2.11 Inactive DFGout‑BBAminus none-none none-out nonTYR APEdihe_aaooi APEdist_nnno 5KW Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 2YIYA 2.49 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno YIY Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 4O91A 2.393 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno NG2 Type2 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5GJDA 2.79 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nnno 6V3 Type2 31 - 495 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q31B 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno TME, A1CNU Allosteric, Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZZA 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU5 Type1 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C3EB 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type1 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7XMKA 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno GO4 Type1 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7XMKB 2.376 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn GO4 Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7YDXB 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 8I2NA 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5HX6B 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 65U Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5TX5B 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 7MJ Type1 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6OCQA 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6RLNB 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn K8K Type1 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTGB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IPG, RCM Type1, Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITJA 1.8 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 1HX Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITJB 1.8 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn 1HX Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7YDXA 2.642 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3CI Type2 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 8I2NB 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo O4U Type2 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FD0A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aannn APEdist_nnnn 3IU Type2 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FD0B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 3IU Type2 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4NEUA 2.57 Inactive DFGout‑BBAminus in-in out-none nonTYR APEdihe_aaiii APEdist_nnni Q1A Type2 6 - 313 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4NEUB 2.57 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanni APEdist_nnnn Q1A Type2 7 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZYA 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZYB 2.32 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaoii APEdist_nnno A1BU6 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZZB 2.68 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1BU5 Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZXA 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9MZXB 2.53 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1BU4 Type3 6 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C3EA 2.6 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno EJY Type3 9 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITHA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITHB 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITIA 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnoo 1HW Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 4ITIB 2.86 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno 1HW Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NYHA 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NYHB 2.1 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno L8D Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q31A 2.05 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNU Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32A 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32B 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32C 2.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 6 - 293 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9Q32D 2.49 Inactive DFGout‑BBAminus out-none out-out nonTYR APEdihe_aaioi APEdist_nnno A1CNV Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FCZA 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 3IF Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 7FCZB 2.21 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno 3IF Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8A 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX7 Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY8B 2.98 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn 1HX Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY9A 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno A1IX9 Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9HY9B 2.29 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno A1IX9 Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DA 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DB 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 7 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DC 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno EJP Type3 10 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6C4DD 2.52 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno EJP Type3 5 - 293 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5HX6A 2.23 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 65U Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 5TX5A 2.56 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno 7MJ Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6HHOA 3.49 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno G4W Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6HHOB 3.49 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn G4W Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6OCQB 2.793 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn M5J Type3 7 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FA 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aanoi APEdist_nnnn JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FB 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 10 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FC 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 9 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6R5FD 3.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaioi APEdist_nnno JSW Type3 11 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6RLNA 2.87 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaiii APEdist_nnno K8K Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NW2A 2.0 Inactive DFGout‑BBAminus out-out out-none nonTYR APEdihe_aanii APEdist_nnnn L4Y Type3 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 6NW2B 2.0 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno L4Y Type3 11 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTYA 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM Type3 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTGA 2.25 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IPG Type3, Type1 8 - 294 0 None None Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK1 RIPK1_HUMAN 9GTYB 2.145 Inactive DFGout‑BBAminus out-out out-out nonTYR APEdihe_aaooi APEdist_nnno RCM, A1IKX Type3, Type1 8 - 294 0 None C34A,C127A,C233A,C240A Receptor-interacting serine/threonine-protein kinase 1 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6ES0A 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaooi APEdist_nnno BW8 Type2 5 - 316 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 6ES0B 2.38 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_nnno BW8 Type2 5 - 315 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL RIPK2 RIPK2_HUMAN 5AR7B 2.71 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno SR8 Type2 6 - 310 0 None None Receptor-interacting serine/threonine-protein kinase 2 Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKA 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKB 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKC 3.1 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZGD Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGKD 3.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZGD Type2 444 - 727 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJA 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnno ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJB 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJC 2.95 Inactive DFGout‑BBAminus in-in none-none nonTYR APEdihe_aanai APEdist_nnnn ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TKL TNNI3K TNI3K_HUMAN 7MGJD 2.95 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaiai APEdist_nnoo ZFS Type2 445 - 726 0 None None Serine/threonine-protein kinase TNNI3K Homo sapiens
TYR ABL1 ABL1_HUMAN 6XRGA 999.0 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai No_ligand No_ligand 229 - 515 0 None G250E,M290L,T389Y Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3QRJA 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 234 - 496 0 None T315I Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3QRJB 1.82 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 233 - 497 0 None T315I Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HZ0A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GIN Type2 233 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HZ0B 2.1 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan GIN Type2 228 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HYYA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 235 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HYYB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HYYC 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HYYD 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 233 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3CS9A 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3CS9B 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3CS9C 2.21 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan NIL Type2 232 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3CS9D 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai NIL Type2 233 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3QRIA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3QRIB 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 919 Type2 232 - 498 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HIWA 2.2 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2HIWB 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 7MP Type2 230 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2E2BA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2E2BB 2.2 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 406 Type2 229 - 497 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 5HU9A 1.529 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaao 66K, 66K Type2, Allosteric 229 - 499 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3PYYA 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, 3YY Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3PYYB 1.85 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao STI, 3YY Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6NPEA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWD Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6NPEB 2.15 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai STI, KWD Type2, Allosteric 233 - 511 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6NPUA 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6NPUB 2.33 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWV Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6NPVA 1.86 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 232 - 500 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 6NPVB 1.86 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai STI, KWP Type2, Allosteric 233 - 510 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 3QRKA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 9DP Type3 229 - 496 0 None None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL2 ABL2_HUMAN 3GVUA 2.05 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai STI, STI Type2, Allosteric 279 - 546 0 None None Tyrosine-protein kinase ABL2 Homo sapiens
TYR ALK ALK_HUMAN 5IUGA 1.93 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao 729 Type2 1093 - 1404 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR ALK ALK_HUMAN 5IUHA 2.1 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oiiai APEdist_aaao 34Y Type2 1093 - 1404 0 None C1097S ALK tyrosine kinase receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 8CGCA 1.925 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai LMR, UIK Allosteric, Type1 547 - 919 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 3BEAA 2.02 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai IXH Type1 547 - 921 0 None A933L Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 2I1MA 1.8 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 5CN Type1 547 - 921 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 8JOTA 1.69 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai UKI Type1 543 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 8W1LA 2.26 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1AE3 Type1 563 - 914 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 2I0VA 2.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 6C3 Type1 544 - 916 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 2I0YA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5CN Type1 548 - 916 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 3KRJA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai KRJ Type1 544 - 914 0 None S686S Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 3KRLA 2.4 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai KRL Type1 545 - 912 0 None S686S Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 7TNHA 2.7 Inactive DFGout‑BBAminus in-none out-in TYR APEdihe_iiiai APEdist_aaai I9W Type1 445 - 912 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 6T2WA 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai M9T Type1 547 - 916 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 3DPKA 1.95 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai 8C5 Type1.5_Back 548 - 912 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 4HW7A 2.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 64M Type2 566 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 4R7HA 2.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P31 Type2 544 - 915 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 4R7IA 2.75 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 567 - 914 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 6N33A 2.25 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 622 Type2 566 - 915 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 7MFCA 2.8 Inactive DFGout‑BBAminus in-none out-in TYR APEdihe_iiiai APEdist_aaai Z6V Type2 567 - 913 0 None C667T,C830S,C907T Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 6WXJA 2.62 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_nniai APEdist_aaai UF4 Type2 559 - 917 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 3LCOA 3.4 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai LC0 Type2 551 - 915 0 None None Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR CSF1R CSF1R_HUMAN 6IG8A 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A7O Type2 550 - 916 0 None S688A Macrophage colony-stimulating factor 1 receptor Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAUA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IF Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAVA 1.76 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAWA 1.601 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 603 - 907 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAXA 1.902 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IM Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAYA 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 907 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAYB 2.19 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IJ Type2 602 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SAZA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IW Type2 603 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SB0A 1.97 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1IZ Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5SB1A 1.53 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 1JI Type2 604 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6FEWA 1.44 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6FEXA 1.291 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Z Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6FILA 1.73 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6W Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6FINA 1.67 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJQ Type2 603 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6FIOA 1.99 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJH Type2 598 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6FIQA 1.79 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oiiai APEdist_aaai DJW Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 3ZOSB 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 4BKJA 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 4BKJB 1.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 4CKRA 2.2 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_niiai APEdist_aaai DI1 Type2 601 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6GWRA 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6GWRB 2.07 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FEW Type2 602 - 908 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6HP9A 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 601 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 6HP9B 1.96 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai GKB Type2 603 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 7BCMA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 7BCMB 2.3 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai TBK Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 7BE6A 1.871 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai TJW Type2 601 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5BVNA 2.21 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5BVOA 1.98 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 4VE Type2 604 - 911 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5FDPA 2.25 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5WR Type2 604 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5FDXA 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 604 - 909 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 5FDXB 2.65 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5X1 Type2 605 - 907 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 3ZOSA 1.92 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI, 0LI Type2, Allosteric 602 - 913 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR1 DDR1_HUMAN 7FEHA 1.61 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 3UI Type3 603 - 912 0 None None Epithelial discoidin domain-containing receptor 1 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERD 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERI 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type1 555 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERA 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERB 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERC 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERE 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERF 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERG 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERH 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERJ 2.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 553 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERK 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 555 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 6FERL 2.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai D6Q Type2 554 - 851 0 None None Discoidin domain-containing receptor 2 Homo sapiens
TYR DDR2 DDR2_HUMAN 7AYMA 2.12 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 4VD Type2 558 - 849 0 None K826E,L847R Discoidin domain-containing receptor 2 Homo sapiens
TYR EGFR EGFR_HUMAN 2RF9A 3.5 Inactive DFGout‑BBAminus out-none in-out TYR APEdihe_ooiai APEdist_aaai No_ligand No_ligand 699 - 983 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZJVA 2.7 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 703 - 985 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 4ZJVB 2.7 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 703 - 982 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HG5A 1.52 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 633 Type1 700 - 1001 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HG7A 1.85 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 630 Type1 702 - 984 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HG8A 1.42 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 634 Type1 700 - 999 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5HG9A 2.15 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 63A Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5U8LA 1.6 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai O44 Type1 702 - 990 0 None None Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5UG8A 1.46 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BP Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5UG9A 1.33 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8AM Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5UGAA 1.82 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BM Type1 703 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EGFR EGFR_HUMAN 5UGCA 1.58 Inactive DFGout‑BBAminus out-out in-in TYR APEdihe_iiiai APEdist_aaai 8BS Type1 702 - 985 0 None T790M,L858R,V948R Epidermal growth factor receptor Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8XPVA 1.55 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 4Z5 Type2 604 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNFA 1.556 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan DXH Type2 606 - 894 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6FNGA 1.038 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_niiai APEdist_aaai DWT Type2 599 - 897 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HESA 1.128 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G0H Type2 599 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HETA 1.208 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G0Q Type2 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HEUA 1.719 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G0N Type2 600 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HEVA 1.28 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai G0K Type2 600 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HEWA 1.268 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao G0E Type2 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HEXA 1.413 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan G02 Type2 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6HEYA 1.367 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_niiai APEdist_aaao FZW Type2 600 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6Q7BA 1.009 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao HO5 Type2 599 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6Q7CA 1.049 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao HOK Type2 599 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6Q7DA 0.978 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao HOT Type2 600 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6Q7EA 1.059 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan HMW Type2 601 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 6Q7GA 1.047 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan HO8 Type2 601 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BM8A 1.68 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao QT1 Type2 605 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BOCA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai QUF Type2 605 - 888 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BODA 1.5 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan QTX Type2 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BOGA 1.47 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan QUU Type2 600 - 895 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BOHA 1.42 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao R0T Type2 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BOIA 1.63 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao R0O Type2 604 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BOKA 2.02 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai R0X Type2 605 - 890 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA2 EPHA2_HUMAN 8BOMA 1.12 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan QU6 Type2 605 - 896 0 None None Ephrin type-A receptor 2 Homo sapiens
TYR EPHA3 EPHA3_HUMAN 3DZQA 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan IFC Type2 609 - 904 0 None None Ephrin type-A receptor 3 Homo sapiens
TYR EPHA7 EPHA7_HUMAN 3DKOA 2.0 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan IHZ Type2 607 - 899 0 None None Ephrin type-A receptor 7 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNIA 1.468 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_nniai APEdist_aaao DXH Type2 607 - 889 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNJA 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR EPHB4 EPHB4_HUMAN 6FNJB 1.239 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao DWT Type2 607 - 888 0 None Y774E,A803V,V870I Ephrin type-B receptor 4 Homo sapiens
TYR FGFR1 FGFR1_HUMAN 4V04B 2.12 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 458 - 765 0 None C488A,C584S Fibroblast growth factor receptor 1 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4QQ5A 2.203 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 37O Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4R6VA 2.353 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan FI3 Type1.5_Back 445 - 750 0 None V550L,R664E Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4UXQA 1.85 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iioai APEdist_aaao 0LI Type2 452 - 750 0 None C477A Fibroblast growth factor receptor 4 Homo sapiens
TYR FGFR4 FGFR4_HUMAN 4TYJA 2.45 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 447 - 753 0 None None Fibroblast growth factor receptor 4 Homo sapiens
TYR FLT1 VGFR1_HUMAN 3HNGA 2.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 8ST Type2 803 - 1158 0 None None Vascular endothelial growth factor receptor 1 Homo sapiens
TYR FLT3 FLT3_HUMAN 4XUFA 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 947 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
TYR FLT3 FLT3_HUMAN 4XUFB 3.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 600 - 946 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
TYR FLT3 FLT3_HUMAN 4RT7A 3.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P30 Type2 599 - 950 0 None None Receptor-type tyrosine-protein kinase FLT3 Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LW0A 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LW0B 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens
TYR IGF1R IGF1R_HUMAN 3LW0C 1.79 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CCX, CCX Type3, Allosteric 983 - 1286 0 None E1097A,E1099A Insulin-like growth factor 1 receptor Homo sapiens
TYR INSR INSR_HUMAN 1IRKA 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 1008 - 1310 0 None None Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 3ETAA 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 351 Type2 1017 - 1310 0 None None Insulin receptor Homo sapiens
TYR INSR INSR_HUMAN 3ETAB 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 351 Type2 1017 - 1310 0 None None Insulin receptor Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7RN6A 1.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioai APEdist_aaao 046 Type2 839 - 1130 0 PTR1007 None Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 3UGCA 1.34 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oioai APEdist_aaao 046 Type2 843 - 1129 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 7TEUA 1.45 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oioai APEdist_aaao I6C Type2 843 - 1131 0 None Y1007F,Y1008F Tyrosine-protein kinase JAK2 Homo sapiens
TYR KDR VGFR2_HUMAN 4AG8A 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 4AGDA 2.81 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 802 - 1169 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3CPBB 2.7 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C92 Type1 820 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2XIRA 1.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 00J Type1.5_Back 816 - 1168 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 4AGCA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AXI Type1.5_Back 801 - 1169 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3WZEA 1.9 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao BAX Type2 815 - 1167 0 None T940V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2OH4A 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iioai APEdist_aaao GIG Type2 816 - 1171 0 PTR1054,PTR1059 None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2P2IA 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 608 Type2 817 - 1172 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3EFLA 2.2 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 706 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3EFLB 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 706 Type2 821 - 1165 0 PTR1054,PTR1059 C817A,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 5EW3A 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 5T2 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 5EW3B 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 5T2 Type2 820 - 1165 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 6GQOA 1.87 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F82 Type2 811 - 1168 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 6GQPA 2.09 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 821 - 1168 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 6GQQA 1.52 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F8B Type2 813 - 1167 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 6XVJA 1.78 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O35 Type2 813 - 1167 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 6XVKA 1.99 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O3E Type2 821 - 1168 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 4ASDA 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai BAX Type2 807 - 1168 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 4ASEA 1.83 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AV9 Type2 807 - 1169 0 None E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3VHEA 1.55 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao 42Q Type2 811 - 1169 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3VHKA 2.49 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao BPK Type2 814 - 1168 0 None None Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2QU5A 2.95 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oooai APEdist_aaao 276 Type2 816 - 1170 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2QU6A 2.1 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 857 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 2RL5A 2.65 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_oooai APEdist_aaao 2RL Type2 815 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3B8QB 2.75 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 900 Type2 820 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3BE2A 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan RAJ Type2 815 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3CP9A 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C19 Type2 817 - 1171 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3CP9B 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C19 Type2 819 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3CPCB 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao C52 Type2 820 - 1165 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3DTWB 2.9 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nooai APEdist_aaao A96 Type2 820 - 1166 0 PTR1054,PTR1059 C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3EWHA 1.6 Inactive DFGout‑BBAminus in-in out-none TYR APEdihe_nniai APEdist_aaai K11 Type2 815 - 1171 0 None C817A,V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KDR VGFR2_HUMAN 3U6JA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 03X Type2 815 - 1171 0 None V916T,E990V Vascular endothelial growth factor receptor 2 Homo sapiens
TYR KIT KIT_HUMAN 8S13A 2.0 Inactive DFGout‑BBAminus in-none out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 554 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S14A 1.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 554 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S15A 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XIN Type1 554 - 929 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 3G0FA 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 566 - 930 0 None D816H Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 3G0FB 2.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B49 Type1 564 - 930 0 None D816H Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 7ZW8A 2.119 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R Type1 554 - 932 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6KLAA 2.109 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DJX Type1 554 - 931 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 4HVSA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 647 Type2 551 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,I690H,C691S,K693D,Q694T,E695S,I756S,L762N,V825D,C844S,L890S,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 7KHGA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai P31 Type2 547 - 931 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S16A 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 566 - 932 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S16B 1.85 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S17A 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S17B 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S18A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1H4U Type2 568 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S18B 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1H4U Type2 578 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQJA 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F82 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQJB 2.33 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F82 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQKA 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 567 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQKB 2.31 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F88 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQLA 2.01 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F8B Type2 568 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQLB 2.01 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao F8B Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQMA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F8H Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6GQMB 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai F8H Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6XV9A 3.38 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O35 Type2 566 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6XV9B 3.38 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O35 Type2 572 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6XVAA 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2K Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6XVAB 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2K Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6XVBA 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2H Type2 569 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6XVBB 2.15 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai O2H Type2 577 - 931 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6HH1A 2.25 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_iiiai APEdist_aaan G4E Type2 565 - 929 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6MOBA 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai JWY Type2 567 - 930 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 1T46A 1.6 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 565 - 933 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 4U0IA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 565 - 933 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 7ZY6A 3.09 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai KCI Type2 557 - 932 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6ITTA 2.103 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AWO Type2 563 - 932 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6ITTB 2.103 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AWO Type2 566 - 932 0 None None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 6ITVA 1.881 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai AWO Type2 569 - 935 0 PTR570 None Mast/stem cell growth factor receptor Kit Homo sapiens
TYR KIT KIT_HUMAN 8S1BB 2.0 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai K3R, K3R, K3R Type2, Allosteric, Allosteric 565 - 930 0 None I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D Mast/stem cell growth factor receptor Kit Homo sapiens
TYR LCK LCK_HUMAN 6PDJA 1.81 Inactive DFGout‑BBAminus out-none in-in TYR APEdihe_iiiai APEdist_aaai ODJ Type1.5_Front 225 - 500 0 PTR394 None Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 2OG8A 2.3 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 1N8 Type2 237 - 499 0 None None Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 2OG8B 2.3 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 1N8 Type2 237 - 499 0 None None Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 3BYSA 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnnao APEdist_aaan AM5 Type2 230 - 501 0 None None Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 3BYUA 2.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioao APEdist_aaai AM6 Type2 231 - 501 0 None None Tyrosine-protein kinase Lck Homo sapiens
TYR LCK LCK_HUMAN 2PL0A 2.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 231 - 498 0 None None Tyrosine-protein kinase Lck Homo sapiens
TYR LMTK3 LMTK3_HUMAN 6SEQA 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 130 - 413 0 None None Serine/threonine-protein kinase LMTK3 Homo sapiens
TYR MERTK MERTK_HUMAN 9KS9B 2.8 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6L Type1 577 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7XHYA 2.16 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan E0X Type1 571 - 862 0 None K591R,K693R,K702R,K856R Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7AAYA 1.87 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao L1X Type2 571 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 9KRYB 2.25 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nnnai APEdist_aaan A1L6J Type2 580 - 863 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7AW4A 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 576 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MERTK MERTK_HUMAN 7AW4B 1.98 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nnnai APEdist_aaan S5E Type3 574 - 862 0 None None Tyrosine-protein kinase Mer Homo sapiens
TYR MET MET_HUMAN 3RHKB 1.94 Inactive DFGout‑BBAminus out-none out-in TYR APEdihe_iiiai APEdist_aaai M97 Type1 1046 - 1344 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8ANSA 2.01 Inactive DFGout‑BBAminus out-none in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8VI1A 3.11 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao A1AB1 Type1.5_Front 1053 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8VI1B 3.11 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai A1AB1 Type1.5_Front 1050 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AN8A 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nnnai APEdist_aaan MDI Type1.5_Front 1073 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8AN8B 2.394 Inactive DFGout‑BBAminus out-out in-none TYR APEdihe_nniai APEdist_aaai MDI Type1.5_Front 1058 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 6SDCA 1.67 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 88Z Type2 1052 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 6SDDA 1.93 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai 353 Type2 1062 - 1344 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 9C1RA 1.59 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan A1ATS Type2 1048 - 1348 0 None D1228N Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3LQ8A 2.02 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 88Z Type2 1053 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 6SD9A 2.35 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 88Z Type2 1062 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4EEVA 1.8 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_niiai APEdist_aaai L1X Type2 1045 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 4MXCA 1.632 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DWF Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 5HTIA 1.66 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 66L Type2 1052 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 7V3SA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 5I9 Type2 1053 - 1346 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3VW8A 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DF6 Type2 1024 - 1352 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3CE3A 2.4 Inactive DFGout‑BBAminus out-out none-out TYR APEdihe_oiiai APEdist_aaai 1FN Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D,L1272L Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3CTHA 2.3 Inactive DFGout‑BBAminus out-out none-out TYR APEdihe_oiiai APEdist_aaai 319 Type2 1052 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3F82A 2.5 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_niiai APEdist_aaai 353 Type2 1055 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 3L8VA 2.4 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_oiiai APEdist_aaai L8V Type2 1054 - 1360 0 None Y1194F,Y1234F,Y1235D Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUUA 1.77 Inactive DFGout‑BBAminus out-out out-in TYR APEdihe_iiiai APEdist_aaai W49 Type3 1059 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUUB 1.77 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W49 Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUVA 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1053 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OUVB 1.783 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3R Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OV7A 1.95 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iioai APEdist_aaao W3W Type3 1051 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OVZA 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1061 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OVZB 2.206 Inactive DFGout‑BBAminus out-out out-out TYR APEdihe_iiiai APEdist_aaao W3N Type3 1057 - 1346 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OWGA 2.631 Inactive DFGout‑BBAminus out-none out-none TYR APEdihe_nnnai APEdist_aaan W40 Type3 1060 - 1344 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OWGB 2.631 Inactive DFGout‑BBAminus out-none out-in TYR APEdihe_iiiai APEdist_aaai W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OWGC 2.631 Inactive DFGout‑BBAminus out-none none-out TYR APEdihe_nniai APEdist_aaao W40 Type3 1060 - 1343 0 None D1228V Hepatocyte growth factor receptor Homo sapiens
TYR MET MET_HUMAN 8OW3A 2.27 Inactive DFGout‑BBAminus out-none none-none TYR APEdihe_nniai APEdist_aaai W40 Type3 1058 - 1345 0 None None Hepatocyte growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6DKGA 2.53 Inactive DFGout‑BBAminus in-out none-in TYR APEdihe_iiiai APEdist_aaai 22L, GO7 Allosteric, Type2 500 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6DKIA 2.11 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 22L, GOD Allosteric, Type2 500 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6D1ZA 1.87 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai FQD, FQM Allosteric, Type3 483 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 7VKMA 2.55 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 502 - 795 0 None G595R High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4PMPA 1.8 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 31W Type1 501 - 787 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5H3QA 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 7HF Type1 484 - 796 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 4PMMA 2.0 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai 31V Type2 501 - 787 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5JFSA 2.07 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 6K0 Type2 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5JFVA 1.59 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nniai APEdist_aaai 6K1 Type2 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5JFWA 1.52 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nniai APEdist_aaai 6K2 Type2 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 5JFXA 1.63 Inactive DFGout‑BBAminus out-in none-none TYR APEdihe_nniai APEdist_aaai 6K4 Type2 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6DKWA 2.91 Inactive DFGout‑BBAminus out-out none-none TYR APEdihe_nniai APEdist_aaai GXA Type2 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6DKWB 2.91 Inactive DFGout‑BBAminus in-out none-in TYR APEdihe_iiiai APEdist_aaai GXA Type2 502 - 793 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6PL2A 2.59 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai OOM Type2 499 - 795 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 7XBIA 2.16 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai CVY Type2 497 - 795 0 None None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 8J5XA 2.092 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A4U Type2 500 - 795 0 None G595R High affinity nerve growth factor receptor Homo sapiens
TYR NTRK1 NTRK1_HUMAN 6PL4A 2.06 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai OO7 Type3 485 - 795 0 SEP677 None High affinity nerve growth factor receptor Homo sapiens
TYR NTRK2 NTRK2_HUMAN 4AT4A 2.36 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai T6E Type2 527 - 822 0 None None BDNF/NT-3 growth factors receptor Homo sapiens
TYR NTRK3 NTRK3_HUMAN 3V5QA 2.2 Inactive DFGout‑BBAminus out-out none-in TYR APEdihe_iiiai APEdist_aaai 0F4 Type2 530 - 832 0 None None NT-3 growth factor receptor Homo sapiens
TYR NTRK3 NTRK3_HUMAN 3V5QB 2.2 Inactive DFGout‑BBAminus out-out none-in TYR APEdihe_iiiai APEdist_aaai 0F4 Type2 530 - 832 0 None None NT-3 growth factor receptor Homo sapiens
TYR NTRK3 NTRK3_HUMAN 6KZCA 2.0 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DZC Type2 528 - 837 0 None None NT-3 growth factor receptor Homo sapiens
TYR NTRK3 NTRK3_HUMAN 6KZDA 1.708 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai DZ6 Type2 528 - 837 0 None None NT-3 growth factor receptor Homo sapiens
TYR PDGFRA PGFRA_HUMAN 9GZHA 2.2 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai A1IRC Type2 583 - 958 0 None T674I Platelet-derived growth factor receptor alpha Homo sapiens
TYR PDGFRA PGFRA_HUMAN 5GRNA 1.77 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 748 Type2 583 - 958 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
TYR PDGFRA PGFRA_HUMAN 6JOLA 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 583 - 957 0 None None Platelet-derived growth factor receptor alpha Homo sapiens
TYR PTK2 FAK1_HUMAN 4KAOA 2.39 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 415 - 686 0 None P410G Focal adhesion kinase 1 Homo sapiens
TYR PTK2 FAK1_HUMAN 4KAOB 2.39 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nniai APEdist_aaao KAO Type2 414 - 686 0 None P410G Focal adhesion kinase 1 Homo sapiens
TYR PTK2B FAK2_HUMAN 3FZSA 1.75 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai B96 Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
TYR PTK2B FAK2_HUMAN 4H1MA 1.99 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nniai APEdist_aaai 0YJ Type2 420 - 690 0 None None Protein-tyrosine kinase 2-beta Homo sapiens
TYR PTK6 PTK6_HUMAN 6CZ4A 1.5 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan FKY Type2 183 - 443 0 None None Protein-tyrosine kinase 6 Homo sapiens
TYR PTK7 PTK7_HUMAN 6VG3A 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1064 0 None None Inactive tyrosine-protein kinase 7 Homo sapiens
TYR PTK7 PTK7_HUMAN 6VG3B 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 788 - 1066 0 None None Inactive tyrosine-protein kinase 7 Homo sapiens
TYR PTK7 PTK7_HUMAN 6VG3C 1.95 Pseudo DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai No_ligand No_ligand 789 - 1063 0 None None Inactive tyrosine-protein kinase 7 Homo sapiens
TYR SRC SRC_HUMAN 7OTEA 2.49 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SRC SRC_HUMAN 7OTEB 2.49 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 261 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens
TYR SYK KSYK_HUMAN 3TUBA 2.23 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan FPU Type2 362 - 633 0 None None Tyrosine-protein kinase SYK Homo sapiens
TYR TEK TIE2_HUMAN 2OO8X 2.2 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_iiiai APEdist_aaao RAJ Type2 836 - 1117 0 None None Angiopoietin-1 receptor Homo sapiens
TYR TEK TIE2_HUMAN 2OSCA 2.8 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao MUH Type2 837 - 1116 0 None None Angiopoietin-1 receptor Homo sapiens
TYR TEK TIE2_HUMAN 2P4IA 2.5 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai MR9 Type2 838 - 1117 0 None None Angiopoietin-1 receptor Homo sapiens
TYR TEK TIE2_HUMAN 6MWEA 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor Homo sapiens
TYR TEK TIE2_HUMAN 6MWEB 2.05 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_oooai APEdist_aaao 919 Type2 816 - 1122 0 None None Angiopoietin-1 receptor Homo sapiens
CMGC MAPK14 MK14_MOUSE 5LARA 1.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 6SH Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4TA 1.98 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nioo O8W Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4UA 1.86 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nioo O98 Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4VA 1.75 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nioo O8Z Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4WA 1.86 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nioo O8T Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4XA 1.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nioo O8Q Type2 1 - 360 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y6VA 2.1 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno OE5 Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6YJCA 1.741 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno OSZ Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6YK7A 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nioo OU2 Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6ZWRA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo OEB Type2 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7BDQA 2.75 Inactive DFGout‑BBAminus in-none none-out nonTYR APEdihe_aaooi APEdist_nnno TJZ Type2 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7BE4A 2.1 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno TK5 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7BE5A 1.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno TKB Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 2PUUA 2.5 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno G2G Type2 5 - 352 0 None N14A Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P5KA 2.09 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P5K Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P78A 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P78 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P79A 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P79 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7AA 2.31 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7A Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7BA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7B Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7CA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno P7C Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
TYR ABL1 ABL1_MOUSE 3K5VA 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3K5VB 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD4A 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD4B 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD6A 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYH, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3OY3A 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3OY3B 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3IK3A 1.9 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3IK3B 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3OXZA 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao 0LI Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3KFAA 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3KFAB 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1FPUA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1FPUB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1IEPA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1IEPB 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1OPJA 1.75 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1OPJB 1.75 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 512 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 2HZNA 2.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai KIN Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD6B 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MS9A 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 230 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MS9B 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSA 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSB 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSC 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSD 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
OTHER DRIK1 C0P4K9_MAIZE 6CPYA 1.7 Pseudo DFGout‑BBAminus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 187 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6CPYB 1.7 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 209 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6EASA 2.0 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn J3A Type1 208 - 492 0 None None Protein kinase superfamily protein Zea mays

All / BBAminus / All

Total number of chains: 73
Active chains: 0
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGout BBAminus 73 100.0% 3KFAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity_label Spatial_Dihedral_labels ChelixSaltbr_label ActLoopNT-ActLoopCT APEtype APEdihe_label APEdist_label Ligand Ligand_type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR SRC SRC_CHICK 7D57A 2.104 Inactive DFGout‑BBAminus out-out out-none TYR APEdihe_nnnai APEdist_aaan 37O Type1 258 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3WA 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1BU Type2 257 - 533 0 None T338M,S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3WB 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1BU Type2 258 - 533 0 None T338M,S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G6HB 2.35 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nnnai APEdist_aaan G6H Type2 258 - 533 0 None T338I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3OEZA 2.4 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao STI Type2 257 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3OEZB 2.4 Inactive DFGout‑BBAminus in-out none-out TYR APEdihe_nnoai APEdist_aaao STI Type2 256 - 533 0 None L317I Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 2OIQA 2.07 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao STI Type2 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3G6GA 2.31 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao G6G Type2 256 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBJA 2.61 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 4A9 Type2 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 4YBJB 2.61 Inactive DFGout‑BBAminus in-none none-out TYR APEdihe_nniai APEdist_aaao 4A9 Type2 259 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7WF5A 1.798 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 257 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 7WF5B 1.798 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 0LI Type2 254 - 533 0 None None Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3VA 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao 1BU Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3VB 2.6 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1BU Type2 256 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ7A 3.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao AQB Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ7B 3.3 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao AQB Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ8A 2.7 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao AQM Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ8B 2.7 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nioai APEdist_aaao AQM Type2 256 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3TZ9A 3.1 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nnoai APEdist_aaao AQU Type2 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5SYSA 2.8 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 72F Type2 258 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 5SYSB 2.8 Inactive DFGout‑BBAminus in-in none-none TYR APEdihe_nnnai APEdist_aaan 72F Type2 258 - 533 0 None V281C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3UB 2.5 Inactive DFGout‑BBAminus in-out none-none TYR APEdihe_nniai APEdist_aaai 1AW Type3 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3TA 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1AU, 1AU Type3, Type1 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
TYR SRC SRC_CHICK 3F3UA 2.5 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_nniai APEdist_aaao 1AW, 1AW Type3, Type1 257 - 533 0 None S345C Proto-oncogene tyrosine-protein kinase Src Gallus gallus
CMGC MAPK14 MK14_MOUSE 5LARA 1.5 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaioi APEdist_iioo 6SH Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4TA 1.98 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nioo O8W Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4UA 1.86 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nioo O98 Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4VA 1.75 Inactive DFGout‑BBAminus in-in out-out nonTYR APEdihe_aaoii APEdist_nioo O8Z Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4WA 1.86 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nioo O8T Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y4XA 1.6 Inactive DFGout‑BBAminus out-out none-out nonTYR APEdihe_aaoii APEdist_nioo O8Q Type2 1 - 360 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6Y6VA 2.1 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno OE5 Type2 4 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6YJCA 1.741 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_nnno OSZ Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6YK7A 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nioo OU2 Type2 5 - 355 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 6ZWRA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnoo OEB Type2 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7BDQA 2.75 Inactive DFGout‑BBAminus in-none none-out nonTYR APEdihe_aaooi APEdist_nnno TJZ Type2 5 - 353 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7BE4A 2.1 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno TK5 Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 7BE5A 1.8 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno TKB Type2 4 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 2PUUA 2.5 Inactive DFGout‑BBAminus in-out none-out nonTYR APEdihe_aaooi APEdist_nnno G2G Type2 5 - 352 0 None N14A Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P5KA 2.09 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P5K Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P78A 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P78 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P79A 2.1 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P79 Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7AA 2.31 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7A Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7BA 1.9 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaoii APEdist_nnno P7B Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
CMGC MAPK14 MK14_MOUSE 3P7CA 2.3 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaooi APEdist_nnno P7C Type3 5 - 352 0 None None Mitogen-activated protein kinase 14 Mus musculus
TYR ABL1 ABL1_MOUSE 3K5VA 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3K5VB 1.74 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STJ, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD4A 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD4B 2.03 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYW, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD6A 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai FYH, STI Allosteric, Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3OY3A 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3OY3B 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai XY3 Type2 229 - 511 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3IK3A 1.9 Inactive DFGout‑BBAminus in-in none-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3IK3B 1.9 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai 0LI Type2 229 - 513 0 None T315I Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3OXZA 2.2 Inactive DFGout‑BBAminus in-in none-out TYR APEdihe_iiiai APEdist_aaao 0LI Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3KFAA 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3KFAB 1.22 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai B91 Type2 229 - 511 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1FPUA 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1FPUB 2.4 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai PRC Type2 229 - 499 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1IEPA 2.1 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1IEPB 2.1 Inactive DFGout‑BBAminus in-out out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1OPJA 1.75 Inactive DFGout‑BBAminus in-in out-out TYR APEdihe_iiiai APEdist_aaao STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 1OPJB 1.75 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 512 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 2HZNA 2.7 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai KIN Type2 229 - 502 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 6HD6B 2.3 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI Type2 229 - 510 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MS9A 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 230 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MS9B 1.8 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS9 Type2, Allosteric 229 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSA 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSB 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSC 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
TYR ABL1 ABL1_MOUSE 3MSSD 1.95 Inactive DFGout‑BBAminus in-in out-in TYR APEdihe_iiiai APEdist_aaai STI, MS7 Type2, Allosteric 232 - 498 0 None None Tyrosine-protein kinase ABL1 Mus musculus
OTHER DRIK1 C0P4K9_MAIZE 6CPYA 1.7 Pseudo DFGout‑BBAminus in-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 187 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6CPYB 1.7 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn No_ligand No_ligand 209 - 492 0 None None Protein kinase superfamily protein Zea mays
OTHER DRIK1 C0P4K9_MAIZE 6EASA 2.0 Pseudo DFGout‑BBAminus out-na out-none nonTYR APEdihe_aannn APEdist_nnnn J3A Type1 208 - 492 0 None None Protein kinase superfamily protein Zea mays