Protein kinases in complex with 032 (Vemurafenib)

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAplus 5 4RZVB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZVA 2.994 Inactive DFGin BLAplus out-out out-out 032 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZVB 2.994 Inactive DFGin BLAplus out-out out-out 032 Type1.5_Back
TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 3OG7A 2.45 Inactive DFGin BLAplus out-out none-out 032 Type1.5_Back
TKL MAP3K20 M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 5HESB 2.14 Inactive DFGin BLAplus out-out none-out 032 Type1
TKL MAP3K20 M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 5HESA 2.14 Inactive DFGin BLAplus out-out out-out 032 Type1.5_Back

Protein kinases in complex with 032

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAplus 5 4RZVB
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZVA 2.994 Inactive DFGin BLAplus out-out out-out 032 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 4RZVB 2.994 Inactive DFGin BLAplus out-out out-out 032 Type1.5_Back
Homo sapiens TKL BRAF BRAF_HUMAN Serine/threonine-protein kinase B-raf 3OG7A 2.45 Inactive DFGin BLAplus out-out none-out 032 Type1.5_Back
Homo sapiens TKL MAP3K20 M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 5HESB 2.14 Inactive DFGin BLAplus out-out none-out 032 Type1
Homo sapiens TKL MAP3K20 M3K20_HUMAN Mitogen-activated protein kinase kinase kinase 20 5HESA 2.14 Inactive DFGin BLAplus out-out out-out 032 Type1.5_Back

Protein kinases in complex with 032

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type