8UWR

ACVR1 (Activin receptor type-1)
Group: TKL
Uniprot: ACVR1_HUMAN
Organism: Homo sapiens
Domain boundary: 208 - 497
Resolu: 2.04

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in XQX Type1 203 - 499 0
Representative sequence - Chain A
- - 206 216
mghhhhhhss gvdlgtenly fqsmqrTVAR DITLLECVGK
226 236 246 256
GRYGEVWRGS WQGENVAVKI FSSRDEKSWF RETELYNTVM
266 276 286 296
LRHENILGFI ASDMTSRHSS TQLWLITHYH EMGSLYDYLQ
306 316 326 336
LTTLDTVSCL RIVLSIASGL AHLHIEIFGT QGKPAIAHRD
346 356 366 376
LKSKNILVKK NGQCCIADLG LAVMHSQSTN QLDVGNNPRV
386 396 406 416
GTKRYMAPEV LDETIQVDCF DSYKRVDIWA FGLVLWEVAR
426 436 446 456
RMVSNGIVED YKPPFYDVVP NDPSFEDMRK VVCVDQQRPN
466 476 486 496
IPNRWFSDPT LTSLAKLMKE CWYQNPSARL TALRIKKTLT

KID
Lower-case residues are disordered in structure.
Mutations: Q207D
Phosphorylation: None