PDB: 4XV2 — TKL BRAF_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 2 100.0% 4XV2B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf

PDB: 4XV2 — TKL BRAF_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 2 100.0% 4XV2B

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TKL BRAF BRAF_HUMAN 4XV2A 2.5 Inactive DFGin‑BLBminus out-out none-out nonTYR APEdihe_aaioi APEdist_nnno P06 Type1.5_Back 449 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens
TKL BRAF BRAF_HUMAN 4XV2B 2.5 Inactive DFGin‑BLBminus in-out none-out nonTYR APEdihe_aaoii APEdist_nnno P06 Type1.5_Back 448 - 705 0 None S446A,S447A,I543A,I544S,I551K,Q562R,L588N,V600E,K630S,F667E,Y673S,A688R Serine/threonine-protein kinase B-raf Homo sapiens

PDB: 4XV2 — TKL BRAF_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism