Protein kinases in complex with 6H3

Total number of genes: 4
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 6G54A
DFGout None 1 5J7SA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6G54A 2.05 Active DFGin BLAminus out-in in-in 6H3 Type1
CMGC MAPK3 MK03_HUMAN Mitogen-activated protein kinase 3 6GESB 2.07 Active DFGin BLAminus in-in in-in 6H3 Type1
CMGC MAPK3 MK03_HUMAN Mitogen-activated protein kinase 3 6GESA 2.07 Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric
TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5J7SA 2.368 Inactive DFGout None out-out none-out 6H3 Type1
TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 6ATEA 2.402 None DFGin BLAminus in-in in-none 6H3 Type1

Protein kinases in complex with 6H3

Total number of genes: 4
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 6G54A
DFGout None 1 5J7SA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC MAPK1 MK01_HUMAN Mitogen-activated protein kinase 1 6G54A 2.05 Active DFGin BLAminus out-in in-in 6H3 Type1
Homo sapiens CMGC MAPK3 MK03_HUMAN Mitogen-activated protein kinase 3 6GESB 2.07 Active DFGin BLAminus in-in in-in 6H3 Type1
Homo sapiens CMGC MAPK3 MK03_HUMAN Mitogen-activated protein kinase 3 6GESA 2.07 Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric
Homo sapiens TKL MAP3K7 M3K7_HUMAN Mitogen-activated protein kinase kinase kinase 7 5J7SA 2.368 Inactive DFGout None out-out none-out 6H3 Type1
Homo sapiens TYR SRC SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src 6ATEA 2.402 None DFGin BLAminus in-in in-none 6H3 Type1

Protein kinases in complex with 6H3

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type