Ligand: 6H3

Total number of chains: 5
Active chains: 1
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 80.0% 6G54A
DFGout None 1 20.0% 5J7SA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CMGC MAPK1 MK01_HUMAN 6G54A 2.05 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6H3 Type1 10 - 356 0 None None Mitogen-activated protein kinase 1
CMGC MAPK3 MK03_HUMAN 6GESB 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3 Type1 25 - 374 0 None None Mitogen-activated protein kinase 3
CMGC MAPK3 MK03_HUMAN 6GESA 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3, EWH Type1, Allosteric 25 - 374 0 None None Mitogen-activated protein kinase 3
TKL MAP3K7 M3K7_HUMAN 5J7SA 2.368 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6H3 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7
TYR SRC SRC_HUMAN 6ATEA 2.402 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan 6H3 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src

Ligand: 6H3

Total number of chains: 5
Active chains: 1
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 80.0% 6G54A
DFGout None 1 20.0% 5J7SA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CMGC MAPK1 MK01_HUMAN 6G54A 2.05 Active DFGin‑BLAminus out-in in-in nonTYR APEdihe_aaiii APEdist_iiii 6H3 Type1 10 - 356 0 None None Mitogen-activated protein kinase 1 Homo sapiens
CMGC MAPK3 MK03_HUMAN 6GESB 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3 Type1 25 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens
CMGC MAPK3 MK03_HUMAN 6GESA 2.07 Inactive DFGin‑BLAminus in-in in-out nonTYR APEdihe_aaiii APEdist_oiii 6H3, EWH Type1, Allosteric 25 - 374 0 None None Mitogen-activated protein kinase 3 Homo sapiens
TKL MAP3K7 M3K7_HUMAN 5J7SA 2.368 Inactive DFGout‑None out-out none-out nonTYR APEdihe_aaoii APEdist_nnno 6H3 Type1 31 - 496 0 None None Mitogen-activated protein kinase kinase kinase 7 Homo sapiens
TYR SRC SRC_HUMAN 6ATEA 2.402 None DFGin‑BLAminus in-in in-none TYR APEdihe_nnnai APEdist_aaan 6H3 Type1 260 - 536 0 None None Proto-oncogene tyrosine-protein kinase Src Homo sapiens

Ligand: 6H3

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism