Protein kinases in complex with BYZ

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 5S7ZB
None None 1 6Q3CA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 9ETPC 2.48 Active DFGin BLAminus in-in in-in BYZ BYZ BYZ Type1 Allosteric Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 9ETPA 2.48 Active DFGin BLAminus in-in in-in BYZ BYZ BYZ BYZ BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q3CA 1.29 Inactive None None out-out out-out BYZ BYZ Type1 Type1
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZB 1.3 Inactive DFGin BLAminus in-out in-in LU8 BYZ Type1 Allosteric
TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric

Protein kinases in complex with BYZ

Total number of genes: 2
Total number of chains: 5
Spatial Dihedral Chains Representative
DFGin BLAminus 4 5S7ZB
None None 1 6Q3CA
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv
Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 9ETPC 2.48 Active DFGin BLAminus in-in in-in BYZ BYZ BYZ Type1 Allosteric Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 9ETPA 2.48 Active DFGin BLAminus in-in in-in BYZ BYZ BYZ BYZ BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric Allosteric
Homo sapiens CMGC CDK2 CDK2_HUMAN Cyclin-dependent kinase 2 6Q3CA 1.29 Inactive None None out-out out-out BYZ BYZ Type1 Type1
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZB 1.3 Inactive DFGin BLAminus in-out in-in LU8 BYZ Type1 Allosteric
Homo sapiens TKL ACVR1 ACVR1_HUMAN Activin receptor type-1 5S7ZA 1.3 Inactive DFGin BLAminus in-out in-in LU8 LU8 LU8 BYZ BYZ Type1 Allosteric Allosteric Allosteric Allosteric

Protein kinases in complex with BYZ

Total number of genes: 0
Total number of chains: 0
Spatial Dihedral Chains Representative
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism Group Gene UniprotID Protein PDB Resolu Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type