Ligand: IYZ

Total number of chains: 4
Active chains: 3
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9I17A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
CAMK PIM1 PIM1_HUMAN 2C3IB 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IYZ Type1 37 - 305 0 None R250G Serine/threonine-protein kinase pim-1
CMGC CLK1 CLK1_HUMAN 6YTAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IYZ Type1 148 - 483 0 None None Dual specificity protein kinase CLK1
CMGC CSNK2A1 CSK21_HUMAN 9I17A 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IYZ Type1 3 - 330 0 None None Casein kinase II subunit alpha
TKL ACVR1 ACVR1_HUMAN 4DYMA 2.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IYZ Type1 207 - 499 0 None R206H Activin receptor type-1

Ligand: IYZ

Total number of chains: 4
Active chains: 3
Total number of genes: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 9I17A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
CAMK PIM1 PIM1_HUMAN 2C3IB 1.9 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IYZ Type1 37 - 305 0 None R250G Serine/threonine-protein kinase pim-1 Homo sapiens
CMGC CLK1 CLK1_HUMAN 6YTAA 2.3 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii IYZ Type1 148 - 483 0 None None Dual specificity protein kinase CLK1 Homo sapiens
CMGC CSNK2A1 CSK21_HUMAN 9I17A 1.55 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii A1IYZ Type1 3 - 330 0 None None Casein kinase II subunit alpha Homo sapiens
TKL ACVR1 ACVR1_HUMAN 4DYMA 2.42 Inactive DFGin‑BLAminus in-out in-out nonTYR APEdihe_aaiii APEdist_iooi IYZ Type1 207 - 499 0 None R206H Activin receptor type-1 Homo sapiens

Ligand: IYZ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism